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The map label for this gene is napA [H]

Identifier: 83311720

GI number: 83311720

Start: 2806949

End: 2808193

Strand: Reverse

Name: napA [H]

Synonym: amb2621

Alternate gene names: 83311720

Gene position: 2808193-2806949 (Counterclockwise)

Preceding gene: 83311721

Following gene: 83311696

Centisome position: 56.54

GC content: 70.28

Gene sequence:

>1245_bases
GTGAGCCTTTTTCTCGTCCAGACGGCGCTGATCATCGGCTTGCCTTATGCCGTGTGGCGGCTGGGGCTGATCGGCCGCCT
GATGCCGCTGGCCGCCGTGCAGATGGCCGTGGGCATCGCCCTGGGGCCGAGCCTGCTGGGCTGGGTGGCCCCGGATGTCT
CGGCGCGGCTGTTTCCGCCGGAATCGCTGGTCGCCCTGGAAGGGCTGGTGCGGCTTGCCGTGGTCTTCTTCGCCTTCTCC
ATCGGCCTGCATTTCGATCTGGCGCAGATCAGGGGGCAGGGGCGCTGCTTCACCGTGCTGGCCCTGTCCAGCGTGGTGGT
GCCGACCCTGGCGGGGGCGGCGGGGGGCTGGTGGCTGTTCGCCGCCGTTCCGGGCGCGGCCGGGGGGCTGGCAAGCCAGT
CCCTATTCGCCGCCGCCATGGGTATCGCCGCCGGAGTGACGGCGCTGCCCGTCCTGGGCGCCGTGGTGCGCGAGATGGGG
CTCGAACGTCACAAGGTGGGCGTGATGGCCCTGGGCGCGGCGGCGTTCAACGATGCTGCCCTATGGGTCGCCGTGGCTCT
GCTGCTGGCGATCAGCCATGGCGGCGACCCCTGGGAGGCCGGGCTGGTGGCCCTGGGCGCTCTGCTGTTCGCCGGGGCGA
TGGTGACGGTGGTGCGTCCGCTGCTGCGCCGCCTGTTCGCCCGCGCCGAGGCCAGCGGCAAGGTTGGCGCCGGCGACGTG
GTGATCCTCACGGTCGGGCTGGCCTTGGCCGCGCTGATCTGCGAGATCATCGGCCTGCATGCGGTGATCGGCGCCTTCCT
GTTCGGGGCGGTGATGCCCCGGCGGGTGGCCCAGGCCATCGTCGGCAGTTTCGAGACCTTCGTGCAGGTGGTGCTGCTGC
CGTTCTTCTTCATCTCGGTGGGGCTGAAGACCCATGCGGCGCTGGGCGGCGGGGCGGCGGCCATCTTCTGGGTGATGAGC
GCGGCGGCGATCCTGGGCAAGCTGGCCTCGGCGCTGCCCGCCTGGATGGGCGGCTGCACCGGGCGGGAAGCCCTGACGCT
GGGCGGGCTGCTGACCTGCAAGGGACTGATGGAACTGGTGGTTCTCACCCTGCTGGCCGAAGCCGGTCTGATCTCCCAGA
CCAGCTTCGGGGCCATGGTGCTGATGGCGCTGTTCGCGACCGTGATGACCAAGCCGCTGGCATCGGTGGGCTGCCGCCCA
CACCCGCCCGGAGGAAAATCCTCCGAACCTCCTTTTCATTCATAA

Upstream 100 bases:

>100_bases
GTCCGGAGATCAACGCCCTGGCCACCATCGTCGTCGCGCTGGTGGGCGTCGCCATCGCCGTGGCGGGCCGGGTGATGATG
ACCAGGGAGAAGCAGGGCGG

Downstream 100 bases:

>100_bases
ATAAACGGAGGGTTCGGGAGGCATGCCTCCCGATCGGGGGCCGGGGCGGAAGCCCCGCATCTCTCCGTTCAGAACTCCTT
CTGCACCTTGGCCCGCAATT

Product: Kef-type K+ transport systems

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MSLFLVQTALIIGLPYAVWRLGLIGRLMPLAAVQMAVGIALGPSLLGWVAPDVSARLFPPESLVALEGLVRLAVVFFAFS
IGLHFDLAQIRGQGRCFTVLALSSVVVPTLAGAAGGWWLFAAVPGAAGGLASQSLFAAAMGIAAGVTALPVLGAVVREMG
LERHKVGVMALGAAAFNDAALWVAVALLLAISHGGDPWEAGLVALGALLFAGAMVTVVRPLLRRLFARAEASGKVGAGDV
VILTVGLALAALICEIIGLHAVIGAFLFGAVMPRRVAQAIVGSFETFVQVVLLPFFFISVGLKTHAALGGGAAAIFWVMS
AAAILGKLASALPAWMGGCTGREALTLGGLLTCKGLMELVVLTLLAEAGLISQTSFGAMVLMALFATVMTKPLASVGCRP
HPPGGKSSEPPFHS

Sequences:

>Translated_414_residues
MSLFLVQTALIIGLPYAVWRLGLIGRLMPLAAVQMAVGIALGPSLLGWVAPDVSARLFPPESLVALEGLVRLAVVFFAFS
IGLHFDLAQIRGQGRCFTVLALSSVVVPTLAGAAGGWWLFAAVPGAAGGLASQSLFAAAMGIAAGVTALPVLGAVVREMG
LERHKVGVMALGAAAFNDAALWVAVALLLAISHGGDPWEAGLVALGALLFAGAMVTVVRPLLRRLFARAEASGKVGAGDV
VILTVGLALAALICEIIGLHAVIGAFLFGAVMPRRVAQAIVGSFETFVQVVLLPFFFISVGLKTHAALGGGAAAIFWVMS
AAAILGKLASALPAWMGGCTGREALTLGGLLTCKGLMELVVLTLLAEAGLISQTSFGAMVLMALFATVMTKPLASVGCRP
HPPGGKSSEPPFHS
>Mature_413_residues
SLFLVQTALIIGLPYAVWRLGLIGRLMPLAAVQMAVGIALGPSLLGWVAPDVSARLFPPESLVALEGLVRLAVVFFAFSI
GLHFDLAQIRGQGRCFTVLALSSVVVPTLAGAAGGWWLFAAVPGAAGGLASQSLFAAAMGIAAGVTALPVLGAVVREMGL
ERHKVGVMALGAAAFNDAALWVAVALLLAISHGGDPWEAGLVALGALLFAGAMVTVVRPLLRRLFARAEASGKVGAGDVV
ILTVGLALAALICEIIGLHAVIGAFLFGAVMPRRVAQAIVGSFETFVQVVLLPFFFISVGLKTHAALGGGAAAIFWVMSA
AAILGKLASALPAWMGGCTGREALTLGGLLTCKGLMELVVLTLLAEAGLISQTSFGAMVLMALFATVMTKPLASVGCRPH
PPGGKSSEPPFHS

Specific function: This is a Na(+)/H(+) antiporter. It can mediate sodium uptake when a transmembrane pH gradient is applied [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322367, Length=414, Percent_Identity=28.0193236714976, Blast_Score=138, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 42197; Mature: 42066

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFLVQTALIIGLPYAVWRLGLIGRLMPLAAVQMAVGIALGPSLLGWVAPDVSARLFPP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
ESLVALEGLVRLAVVFFAFSIGLHFDLAQIRGQGRCFTVLALSSVVVPTLAGAAGGWWLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEHE
AAVPGAAGGLASQSLFAAAMGIAAGVTALPVLGAVVREMGLERHKVGVMALGAAAFNDAA
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEECHHHHHHHH
LWVAVALLLAISHGGDPWEAGLVALGALLFAGAMVTVVRPLLRRLFARAEASGKVGAGDV
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
VILTVGLALAALICEIIGLHAVIGAFLFGAVMPRRVAQAIVGSFETFVQVVLLPFFFISV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLKTHAALGGGAAAIFWVMSAAAILGKLASALPAWMGGCTGREALTLGGLLTCKGLMELV
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
VLTLLAEAGLISQTSFGAMVLMALFATVMTKPLASVGCRPHPPGGKSSEPPFHS
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLFLVQTALIIGLPYAVWRLGLIGRLMPLAAVQMAVGIALGPSLLGWVAPDVSARLFPP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
ESLVALEGLVRLAVVFFAFSIGLHFDLAQIRGQGRCFTVLALSSVVVPTLAGAAGGWWLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEHE
AAVPGAAGGLASQSLFAAAMGIAAGVTALPVLGAVVREMGLERHKVGVMALGAAAFNDAA
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEECHHHHHHHH
LWVAVALLLAISHGGDPWEAGLVALGALLFAGAMVTVVRPLLRRLFARAEASGKVGAGDV
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
VILTVGLALAALICEIIGLHAVIGAFLFGAVMPRRVAQAIVGSFETFVQVVLLPFFFISV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLKTHAALGGGAAAIFWVMSAAAILGKLASALPAWMGGCTGREALTLGGLLTCKGLMELV
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
VLTLLAEAGLISQTSFGAMVLMALFATVMTKPLASVGCRPHPPGGKSSEPPFHS
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1312090; 1325937 [H]