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The map label for this gene is ycfH [C]

Identifier: 83311546

GI number: 83311546

Start: 2623182

End: 2623961

Strand: Reverse

Name: ycfH [C]

Synonym: amb2447

Alternate gene names: 83311546

Gene position: 2623961-2623182 (Counterclockwise)

Preceding gene: 83311547

Following gene: 83311545

Centisome position: 52.83

GC content: 64.74

Gene sequence:

>780_bases
ATGCTGGTCGACAGCCACTGCCACCTGGATTTTCCCGATTTCGCCGACGACCTCGATGGCGTGGTCGGGCGCGCGGGCGC
GGCGGGAGTAGGGGTGCTGCTGACCATTGGCACCCACGTCACCCGCTATGATCAGGTCGTCAAGGTCGCCGAGCGTTTCG
ACAATGTCTGGGCCACCGTGGGCATCCATCCGCACGAGGCGGGCGTCGAGCCCTACGCCGATCTGGACACCCTGCTGCGC
TTGGCCGAGCATCCCAAGGTGGTGGCGTTCGGCGAGACCGGGCTGGACTATTACTACGACAAGAGCCCACGCGAGCAGCA
GCGGCATTCGTTCCGCATCCATATCGAGGCAGCCCGGCGAACGGGTCTGCCGGTGATCGTCCATACCCGCGATGCCGACG
ACGATACTGCGGCGATCCTGGCCGAGGAGATGGGGAAGGGGGCCTTCACCGGGCTGATTCACTGTTTCAGCTCACGGCCG
GACTTCGCTGAAAAGGCTGTGAAATTGGGCCTGTTCATCTCGGCGTCTGGCATCATGACCTTCAAGACCGCCGACATCTT
GCGCGACACCCTGGCCGGCGTGCCGCTGGACCGCCTGCTGGTGGAAACCGACGCCCCCTATCTGGCGCCCATCCCGTTTC
GCGGCAAACGGAACGAACCTGCCTATGTGGCCCACACCGCCGCCCGGCTGGCCGAGGTCAAGGGCGTCACCATGGCCGAG
ATGGAAACCGCCACCACCGACAACTTCCACCGTCTGTTCAAGAAGGTGGCGCGGCCATGA

Upstream 100 bases:

>100_bases
CTTCGCCTTCTTCGGCCCCGGTCATGCCCTGAAGGCCGGGATTTCCCTGCCGACGCCCCAGGGCGTGTTCCCGCGCTATG
TGGAAGAGGTTTCCGCCTAA

Downstream 100 bases:

>100_bases
AGGTCACCATCCTCGGCTGTGGCGGCGCCGCCGGCGTTCCGACCATTTCCGGGGGCTGGGGGGCCTGCGATCCCGCCAAT
CCGCGCAACCGCCGCCTGCG

Product: Mg-dependent DNase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MLVDSHCHLDFPDFADDLDGVVGRAGAAGVGVLLTIGTHVTRYDQVVKVAERFDNVWATVGIHPHEAGVEPYADLDTLLR
LAEHPKVVAFGETGLDYYYDKSPREQQRHSFRIHIEAARRTGLPVIVHTRDADDDTAAILAEEMGKGAFTGLIHCFSSRP
DFAEKAVKLGLFISASGIMTFKTADILRDTLAGVPLDRLLVETDAPYLAPIPFRGKRNEPAYVAHTAARLAEVKGVTMAE
METATTDNFHRLFKKVARP

Sequences:

>Translated_259_residues
MLVDSHCHLDFPDFADDLDGVVGRAGAAGVGVLLTIGTHVTRYDQVVKVAERFDNVWATVGIHPHEAGVEPYADLDTLLR
LAEHPKVVAFGETGLDYYYDKSPREQQRHSFRIHIEAARRTGLPVIVHTRDADDDTAAILAEEMGKGAFTGLIHCFSSRP
DFAEKAVKLGLFISASGIMTFKTADILRDTLAGVPLDRLLVETDAPYLAPIPFRGKRNEPAYVAHTAARLAEVKGVTMAE
METATTDNFHRLFKKVARP
>Mature_259_residues
MLVDSHCHLDFPDFADDLDGVVGRAGAAGVGVLLTIGTHVTRYDQVVKVAERFDNVWATVGIHPHEAGVEPYADLDTLLR
LAEHPKVVAFGETGLDYYYDKSPREQQRHSFRIHIEAARRTGLPVIVHTRDADDDTAAILAEEMGKGAFTGLIHCFSSRP
DFAEKAVKLGLFISASGIMTFKTADILRDTLAGVPLDRLLVETDAPYLAPIPFRGKRNEPAYVAHTAARLAEVKGVTMAE
METATTDNFHRLFKKVARP

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=275, Percent_Identity=34.9090909090909, Blast_Score=134, Evalue=8e-32,
Organism=Homo sapiens, GI110349734, Length=273, Percent_Identity=35.1648351648352, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI226061853, Length=279, Percent_Identity=34.0501792114695, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI226061614, Length=260, Percent_Identity=33.0769230769231, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI226061595, Length=233, Percent_Identity=33.9055793991416, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI225903424, Length=266, Percent_Identity=28.1954887218045, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI14042943, Length=267, Percent_Identity=26.2172284644195, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI225903439, Length=249, Percent_Identity=24.4979919678715, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1787342, Length=256, Percent_Identity=48.046875, Blast_Score=214, Evalue=3e-57,
Organism=Escherichia coli, GI48994985, Length=259, Percent_Identity=33.5907335907336, Blast_Score=143, Evalue=9e-36,
Organism=Escherichia coli, GI87082439, Length=257, Percent_Identity=35.0194552529183, Blast_Score=142, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17559024, Length=282, Percent_Identity=29.0780141843972, Blast_Score=121, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71980746, Length=265, Percent_Identity=26.4150943396226, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17565396, Length=302, Percent_Identity=28.476821192053, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17543026, Length=300, Percent_Identity=26.3333333333333, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24648690, Length=218, Percent_Identity=32.5688073394495, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI221330018, Length=209, Percent_Identity=29.1866028708134, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24586117, Length=209, Percent_Identity=29.1866028708134, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28464; Mature: 28464

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVDSHCHLDFPDFADDLDGVVGRAGAAGVGVLLTIGTHVTRYDQVVKVAERFDNVWATV
CEECCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEE
GIHPHEAGVEPYADLDTLLRLAEHPKVVAFGETGLDYYYDKSPREQQRHSFRIHIEAARR
CCCCHHCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHCCEEEEEEEEHHH
TGLPVIVHTRDADDDTAAILAEEMGKGAFTGLIHCFSSRPDFAEKAVKLGLFISASGIMT
CCCEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHEEEECCCEEE
FKTADILRDTLAGVPLDRLLVETDAPYLAPIPFRGKRNEPAYVAHTAARLAEVKGVTMAE
EHHHHHHHHHHHCCCHHHHEEECCCCEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCHHH
METATTDNFHRLFKKVARP
HHHHCCHHHHHHHHHHCCC
>Mature Secondary Structure
MLVDSHCHLDFPDFADDLDGVVGRAGAAGVGVLLTIGTHVTRYDQVVKVAERFDNVWATV
CEECCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEE
GIHPHEAGVEPYADLDTLLRLAEHPKVVAFGETGLDYYYDKSPREQQRHSFRIHIEAARR
CCCCHHCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHCCEEEEEEEEHHH
TGLPVIVHTRDADDDTAAILAEEMGKGAFTGLIHCFSSRPDFAEKAVKLGLFISASGIMT
CCCEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHEEEECCCEEE
FKTADILRDTLAGVPLDRLLVETDAPYLAPIPFRGKRNEPAYVAHTAARLAEVKGVTMAE
EHHHHHHHHHHHCCCHHHHEEECCCCEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCHHH
METATTDNFHRLFKKVARP
HHHHCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]