Click here to switch to the map view.

The map label for this gene is ytfL [C]

Identifier: 83311250

GI number: 83311250

Start: 2327781

End: 2329091

Strand: Reverse

Name: ytfL [C]

Synonym: amb2151

Alternate gene names: 83311250

Gene position: 2329091-2327781 (Counterclockwise)

Preceding gene: 83311255

Following gene: 83311248

Centisome position: 46.89

GC content: 67.81

Gene sequence:

>1311_bases
ATGCGCCTCGCTTTCGAAATTGCCGTGATCATCGCCCTGGTTGTCCTCAACGGCTGCTTCGCCATGTCCGAACTGGCCAT
CGTCTCCGCCCGCCGCGCCCGGCTGGCCACCCTGGCCGCCGAGGGCAGCAAGGGAGCCCGGGCAGCCCTGGACCTGGCCG
ACAACCCCACCCGCTTCCTGTCCTCGGTGCAGATCGGCATCACCCTGGTGGGCGTGCTGGCCGGCGCCTATTCCGGCGCC
ACCCTGGCCGAACAGTTGGGAGCCTGGATCGCGGCGGAATTTCCCGTGGCGGCGTCAGTGGCGCCGGGCGTCGCCATCGC
CCTGGTCGTGGGCGCCATCACCTATGCCTCGCTGATCGTCGGCGAACTGGTGCCAAAGCACATCGCCCTGGCCAATCCCG
AGGGCATCGCCGAGCGGGTGGCGCGGCCCATGGCCATGGTGGCCCGCCTGACCTCGCCGCTGATCTGGCTGCTGGAAGGG
TCCAGCCATGCCGTGATCCGCATGCTGGGAATCCGCCGGTCGGATGATCACGCCGTCACCGAGGAGGAAGTGCGGGCCAT
GATCGCCGAAGGTACCGAAAGCGGTGTCTTCGAGCCGGAGGAAGAGGAGATGATCTCCGGCGTCATGCGCTTTGGCGACC
GCCGCATCCGGGGAATCATGACACCCCGCGCCAACATGGTCTGGATCGATCTCGACTGGGATGCCGACGATATCCTGAAG
ACGCTGCGCGACTGCCCCCATTCCCGCCTGCCGGTCTGCCGGGGCGGCCTCGACGAGACACTGGGCGTGGTCCAGGCCAA
GGACCTCCTCAACGCCGCCATCGACCAGCGCCCGGTGGACGTCGCGGCGGCCGTCAAGGTGCTGGCGGTGGTGCACGACA
ACGCCCCCGCGCTGCACGTTCTGGATGTTCTGAAACAGTCGGACATCCACATGGCGCTGGTGGTGGACGAATACGGCAGC
GTCGAGGGCATCGTCACCGCCGCCGACATCCTGGGCTCGATCCTCGGCACCTTGTCCGAACACGGCGAGGAATACCAGGG
CACCATCACCGAGCGGGAGGACGGCTCCTGGCTGATGGACGGCGACGTGGCGGTGGATCTGGCCGCCGAGCGGCTGGGCT
GCCGGGTGATGAAGGAAGGCGGCGGCGACTACACCACCGCCGCCGGGTTCATCCTGTCCCAGGTCCGCACCATCCCGTCG
GCCGGCGACCACTTCATCAGGGACGGCTGGCGCTTCGAGGTGGTGGACATGGACGGGCGGCGCATCGACAAGATCCTGGT
GTCAAGGGAGACCGGGACTTTGGGGATGTGA

Upstream 100 bases:

>100_bases
CCATCAGCGGCAATCGCTTCGGATCGCGCGCACCACCCCGGTCAGGGGGGAGCGGAGAAACCATGATTGCCCCGTGGGGG
GAATCAGGCATCATCACCCC

Downstream 100 bases:

>100_bases
AGAAAGGCGGCCGGGACGGCCGCCCCCGCCCTCAGATATACTGTCCCGAATCCACCTTGATCACCTCGCCGGTGATGCAG
CGGGCCGCGTCCGACAGCAG

Product: hemolysin-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MRLAFEIAVIIALVVLNGCFAMSELAIVSARRARLATLAAEGSKGARAALDLADNPTRFLSSVQIGITLVGVLAGAYSGA
TLAEQLGAWIAAEFPVAASVAPGVAIALVVGAITYASLIVGELVPKHIALANPEGIAERVARPMAMVARLTSPLIWLLEG
SSHAVIRMLGIRRSDDHAVTEEEVRAMIAEGTESGVFEPEEEEMISGVMRFGDRRIRGIMTPRANMVWIDLDWDADDILK
TLRDCPHSRLPVCRGGLDETLGVVQAKDLLNAAIDQRPVDVAAAVKVLAVVHDNAPALHVLDVLKQSDIHMALVVDEYGS
VEGIVTAADILGSILGTLSEHGEEYQGTITEREDGSWLMDGDVAVDLAAERLGCRVMKEGGGDYTTAAGFILSQVRTIPS
AGDHFIRDGWRFEVVDMDGRRIDKILVSRETGTLGM

Sequences:

>Translated_436_residues
MRLAFEIAVIIALVVLNGCFAMSELAIVSARRARLATLAAEGSKGARAALDLADNPTRFLSSVQIGITLVGVLAGAYSGA
TLAEQLGAWIAAEFPVAASVAPGVAIALVVGAITYASLIVGELVPKHIALANPEGIAERVARPMAMVARLTSPLIWLLEG
SSHAVIRMLGIRRSDDHAVTEEEVRAMIAEGTESGVFEPEEEEMISGVMRFGDRRIRGIMTPRANMVWIDLDWDADDILK
TLRDCPHSRLPVCRGGLDETLGVVQAKDLLNAAIDQRPVDVAAAVKVLAVVHDNAPALHVLDVLKQSDIHMALVVDEYGS
VEGIVTAADILGSILGTLSEHGEEYQGTITEREDGSWLMDGDVAVDLAAERLGCRVMKEGGGDYTTAAGFILSQVRTIPS
AGDHFIRDGWRFEVVDMDGRRIDKILVSRETGTLGM
>Mature_436_residues
MRLAFEIAVIIALVVLNGCFAMSELAIVSARRARLATLAAEGSKGARAALDLADNPTRFLSSVQIGITLVGVLAGAYSGA
TLAEQLGAWIAAEFPVAASVAPGVAIALVVGAITYASLIVGELVPKHIALANPEGIAERVARPMAMVARLTSPLIWLLEG
SSHAVIRMLGIRRSDDHAVTEEEVRAMIAEGTESGVFEPEEEEMISGVMRFGDRRIRGIMTPRANMVWIDLDWDADDILK
TLRDCPHSRLPVCRGGLDETLGVVQAKDLLNAAIDQRPVDVAAAVKVLAVVHDNAPALHVLDVLKQSDIHMALVVDEYGS
VEGIVTAADILGSILGTLSEHGEEYQGTITEREDGSWLMDGDVAVDLAAERLGCRVMKEGGGDYTTAAGFILSQVRTIPS
AGDHFIRDGWRFEVVDMDGRRIDKILVSRETGTLGM

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=380, Percent_Identity=28.1578947368421, Blast_Score=179, Evalue=5e-45,
Organism=Escherichia coli, GI1790664, Length=427, Percent_Identity=30.4449648711944, Blast_Score=238, Evalue=8e-64,
Organism=Escherichia coli, GI145693175, Length=417, Percent_Identity=26.8585131894484, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87082033, Length=274, Percent_Identity=28.1021897810219, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1788119, Length=270, Percent_Identity=29.6296296296296, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786879, Length=251, Percent_Identity=27.4900398406374, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 46546; Mature: 46546

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLAFEIAVIIALVVLNGCFAMSELAIVSARRARLATLAAEGSKGARAALDLADNPTRFL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHH
SSVQIGITLVGVLAGAYSGATLAEQLGAWIAAEFPVAASVAPGVAIALVVGAITYASLIV
HHHHHHHHHHHHHHHCCCCHHHHHHHCCHHEECCCCHHHCCCHHHHHHHHHHHHHHHHHH
GELVPKHIALANPEGIAERVARPMAMVARLTSPLIWLLEGSSHAVIRMLGIRRSDDHAVT
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEHEECCCCCCCCCCC
EEEVRAMIAEGTESGVFEPEEEEMISGVMRFGDRRIRGIMTPRANMVWIDLDWDADDILK
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHEEECCCCCEEEEEECCCHHHHHH
TLRDCPHSRLPVCRGGLDETLGVVQAKDLLNAAIDQRPVDVAAAVKVLAVVHDNAPALHV
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHH
LDVLKQSDIHMALVVDEYGSVEGIVTAADILGSILGTLSEHGEEYQGTITEREDGSWLMD
HHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHCCCEEECCCCCEEEC
GDVAVDLAAERLGCRVMKEGGGDYTTAAGFILSQVRTIPSAGDHFIRDGWRFEVVDMDGR
CCCHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEEECCCC
RIDKILVSRETGTLGM
HHHHHHEECCCCCCCC
>Mature Secondary Structure
MRLAFEIAVIIALVVLNGCFAMSELAIVSARRARLATLAAEGSKGARAALDLADNPTRFL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHH
SSVQIGITLVGVLAGAYSGATLAEQLGAWIAAEFPVAASVAPGVAIALVVGAITYASLIV
HHHHHHHHHHHHHHHCCCCHHHHHHHCCHHEECCCCHHHCCCHHHHHHHHHHHHHHHHHH
GELVPKHIALANPEGIAERVARPMAMVARLTSPLIWLLEGSSHAVIRMLGIRRSDDHAVT
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEHEECCCCCCCCCCC
EEEVRAMIAEGTESGVFEPEEEEMISGVMRFGDRRIRGIMTPRANMVWIDLDWDADDILK
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHEEECCCCCEEEEEECCCHHHHHH
TLRDCPHSRLPVCRGGLDETLGVVQAKDLLNAAIDQRPVDVAAAVKVLAVVHDNAPALHV
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHH
LDVLKQSDIHMALVVDEYGSVEGIVTAADILGSILGTLSEHGEEYQGTITEREDGSWLMD
HHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHCCCEEECCCCCEEEC
GDVAVDLAAERLGCRVMKEGGGDYTTAAGFILSQVRTIPSAGDHFIRDGWRFEVVDMDGR
CCCHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEEECCCC
RIDKILVSRETGTLGM
HHHHHHEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]