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The map label for this gene is nrdR

Identifier: 83311173

GI number: 83311173

Start: 2254013

End: 2254474

Strand: Reverse

Name: nrdR

Synonym: amb2074

Alternate gene names: 83311173

Gene position: 2254474-2254013 (Counterclockwise)

Preceding gene: 83311174

Following gene: 83311172

Centisome position: 45.39

GC content: 56.93

Gene sequence:

>462_bases
ATGCGATGCCCGTTTTGCGGACAGGATGACACCCAGGTAAAGGATTCACGCCCAACCGATGACAATGCGGCCATCCGACG
CCGCCGAGCTTGTCCAGGGTGTGGATCGCGGTTCACCACTTTCGAGCGGGTTCAAATCCGTGATCTGGTCGTGGTCAAAA
AGGACGGATCACGCTCGACCTTCGACCGGGAGAAGGTGGTCAAGTCACTTCAGATCGCCCTGCGGAAACGCCCTGTCGAA
GATGACCAGATCGAACGCATTGCCAATGGCATCTACCGCCGCCTTGAGAGCTTGGGAGAAAACGAGGTTCCGTCCAAGCT
CATCGGTGAACTGGTGATGGACGTGCTGATGGAGATGGATCAGGTGGCCTATTTGCGGTACGCCTCGGTCTACCGGAACT
TCCGCGAAGCCAAAGATTTTGGGGATTTCCTGGGGAAGATGGGAACCAGCAGCGGGGATTGA

Upstream 100 bases:

>100_bases
ACTGGTGCCGAAATTCTGGGCAAGTGATGTCACCGCTCTTGCTGAAGGCAGCCATTTCCTGAAAAGATTGCCGTAAGTAA
CGATAGAGGGAAGCAATCCA

Downstream 100 bases:

>100_bases
TACGCCCTGACGATCACAGCACAAGGCATTGCCCTACCATACCCTTCCGTTGGAATGTGCTTATCATGTTCAGCCGTTAT
GTGGGCATCGACTACTCCGG

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MRCPFCGQDDTQVKDSRPTDDNAAIRRRRACPGCGSRFTTFERVQIRDLVVVKKDGSRSTFDREKVVKSLQIALRKRPVE
DDQIERIANGIYRRLESLGENEVPSKLIGELVMDVLMEMDQVAYLRYASVYRNFREAKDFGDFLGKMGTSSGD

Sequences:

>Translated_153_residues
MRCPFCGQDDTQVKDSRPTDDNAAIRRRRACPGCGSRFTTFERVQIRDLVVVKKDGSRSTFDREKVVKSLQIALRKRPVE
DDQIERIANGIYRRLESLGENEVPSKLIGELVMDVLMEMDQVAYLRYASVYRNFREAKDFGDFLGKMGTSSGD
>Mature_153_residues
MRCPFCGQDDTQVKDSRPTDDNAAIRRRRACPGCGSRFTTFERVQIRDLVVVKKDGSRSTFDREKVVKSLQIALRKRPVE
DDQIERIANGIYRRLESLGENEVPSKLIGELVMDVLMEMDQVAYLRYASVYRNFREAKDFGDFLGKMGTSSGD

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=147, Percent_Identity=46.2585034013605, Blast_Score=136, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR2_MAGSA (Q2W5J7)

Other databases:

- EMBL:   AP007255
- RefSeq:   YP_421437.1
- STRING:   Q2W5J7
- GeneID:   3804904
- GenomeReviews:   AP007255_GR
- KEGG:   mag:amb2074
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   ERRWIAT
- PhylomeDB:   Q2W5J7
- ProtClustDB:   PRK00464
- BioCyc:   MMAG342108:AMB2074-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17505; Mature: 17505

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPFCGQDDTQVKDSRPTDDNAAIRRRRACPGCGSRFTTFERVQIRDLVVVKKDGSRST
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHEEEEECCCCCCH
FDREKVVKSLQIALRKRPVEDDQIERIANGIYRRLESLGENEVPSKLIGELVMDVLMEMD
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
QVAYLRYASVYRNFREAKDFGDFLGKMGTSSGD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRCPFCGQDDTQVKDSRPTDDNAAIRRRRACPGCGSRFTTFERVQIRDLVVVKKDGSRST
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHEEEEECCCCCCH
FDREKVVKSLQIALRKRPVEDDQIERIANGIYRRLESLGENEVPSKLIGELVMDVLMEMD
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
QVAYLRYASVYRNFREAKDFGDFLGKMGTSSGD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA