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The map label for this gene is aphA [H]

Identifier: 83311104

GI number: 83311104

Start: 2175635

End: 2177011

Strand: Reverse

Name: aphA [H]

Synonym: amb2005

Alternate gene names: 83311104

Gene position: 2177011-2175635 (Counterclockwise)

Preceding gene: 83311105

Following gene: 83311096

Centisome position: 43.83

GC content: 63.69

Gene sequence:

>1377_bases
TTGAAAGTTTCCTGGCGCATAACGGGCATCTATGCCGCCGTCGGACTGGGCTGGATTTTCCTCTCGTCCCTAGCCGTCTG
GATTGGTGTCGGCGAGCCGCCAGGCATTGCCTCCCTGCTGGAACTCGGCAAGGGCTGCGTCTTCATCCTGGTGACGGCAC
TCATGCTGCTGGTGCTGCTGCGGCGCTGGGAGACCGAGTTGAACCGCCGGGGAGCTGCCCTGGCGGAAAGCAACCGGGAA
TTGTCCGAGGTGAATACCCGCCTATCGGGCATCATGCGCGGGTCTCAGGATCTGATCGCCGCCTGGGACCGCGACAAACG
CCTTACAGCCTTTAATCCCCGCTATCAGGCCGTGTGCTGGAACTTCTTTGAATGCGACGTAAAGATCGGCATGCCCATTG
AGGAAGTCTTCGGCAGGGTCCCGGATCGCCTCCAACTGTTCTCAGAATGCTGGGACCGGACCCTGGCCGGCGAATCCTTC
GTCCAGCTGCAGTCGCTGACCACCGATGGCGATATCGGCTGGTTCGAGACCAGCTATGGCTCCCTGGCCGGGGAAGACGG
CCGCCCGTGCGGCGGCTTTCATATCGTGCGGGATGTCACCGACCGCGTCCGGGCCGAGGAAAGCGGCCGCCTGCAGGCGG
AAAAGCTGGCCAAGGCCGTGGAGACCCTGACCGAAGCCAATGCCGAACTGGAACGCTTCGCCTTCGTCGCCTCCCACGAT
CTGCAGGAGCCGCTGCGCACCGTCGCCTGCTTCGCCCAATTGGTCGAGCGCGACTACGGCGAAGGACTGGATGATCGAGG
CCGGCAGTACCTGGAACTGGTCACCGGCGGCGCCATTCGCATGCATGAAATGGTCAACGATCTGCTGGCCTATTCCCGCA
CCAGCCGCAGCGAAGGCCGAATCGAACGGGTGTCGGCGGCAACGGCCTGCCAGAGCGCACTGAACAACCTGCGCGAAGCC
ATCGATTCCAGCGGGGCGGAGATCACGGTCGCCCCGCTGCCCGAGGTGGATGCCGACCCAGTCATGCTGATCCAGGTTTT
CCAGAACCTGGTCGGCAACGCGGTCAAATACCGCAAGGAGGGGCTTGTTCCGCACATCCAGGTGAGCGCGGAGCAGGCCG
GGCGCTACTGGCAGTTCTCGGTCGCCGACAACGGAATCGGCTTCGACCCGAAGGAACAGGATGTATTCGAGCTGTTCCGC
CGCCTACACCCCCATTCCAGCTATGCCGGCACCGGTGTGGGCCTGGCCATATGCAAACGGATCGTCAACCGGCTGGGCGG
CCATATCTGGGTAGAATCAACCCCTGGCGCGGGCAGCGTCTTCCGCTTCACCCTGCCGCTGGGCGAAGAGAGTCCGCCAG
CGCCCGCGCCTGTTTGA

Upstream 100 bases:

>100_bases
GCCGAAACTGCCGGACTGACGCATTCACTGTGCCACAAGAACAACTTTCTGGTAGCCTCAGCATCCAAAGGCGTCCACCA
ATCCGAGGGAATTCATCGCA

Downstream 100 bases:

>100_bases
GAGCGGCCTCGAATTCCGGCTGAACCCCGCGGGTCCCAGCGGCGTACATCAGGTTCTCCACCAGGCCGAAATCCTCCACC
AGCATGCCGTGCTGGCGACA

Product: Signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MKVSWRITGIYAAVGLGWIFLSSLAVWIGVGEPPGIASLLELGKGCVFILVTALMLLVLLRRWETELNRRGAALAESNRE
LSEVNTRLSGIMRGSQDLIAAWDRDKRLTAFNPRYQAVCWNFFECDVKIGMPIEEVFGRVPDRLQLFSECWDRTLAGESF
VQLQSLTTDGDIGWFETSYGSLAGEDGRPCGGFHIVRDVTDRVRAEESGRLQAEKLAKAVETLTEANAELERFAFVASHD
LQEPLRTVACFAQLVERDYGEGLDDRGRQYLELVTGGAIRMHEMVNDLLAYSRTSRSEGRIERVSAATACQSALNNLREA
IDSSGAEITVAPLPEVDADPVMLIQVFQNLVGNAVKYRKEGLVPHIQVSAEQAGRYWQFSVADNGIGFDPKEQDVFELFR
RLHPHSSYAGTGVGLAICKRIVNRLGGHIWVESTPGAGSVFRFTLPLGEESPPAPAPV

Sequences:

>Translated_458_residues
MKVSWRITGIYAAVGLGWIFLSSLAVWIGVGEPPGIASLLELGKGCVFILVTALMLLVLLRRWETELNRRGAALAESNRE
LSEVNTRLSGIMRGSQDLIAAWDRDKRLTAFNPRYQAVCWNFFECDVKIGMPIEEVFGRVPDRLQLFSECWDRTLAGESF
VQLQSLTTDGDIGWFETSYGSLAGEDGRPCGGFHIVRDVTDRVRAEESGRLQAEKLAKAVETLTEANAELERFAFVASHD
LQEPLRTVACFAQLVERDYGEGLDDRGRQYLELVTGGAIRMHEMVNDLLAYSRTSRSEGRIERVSAATACQSALNNLREA
IDSSGAEITVAPLPEVDADPVMLIQVFQNLVGNAVKYRKEGLVPHIQVSAEQAGRYWQFSVADNGIGFDPKEQDVFELFR
RLHPHSSYAGTGVGLAICKRIVNRLGGHIWVESTPGAGSVFRFTLPLGEESPPAPAPV
>Mature_458_residues
MKVSWRITGIYAAVGLGWIFLSSLAVWIGVGEPPGIASLLELGKGCVFILVTALMLLVLLRRWETELNRRGAALAESNRE
LSEVNTRLSGIMRGSQDLIAAWDRDKRLTAFNPRYQAVCWNFFECDVKIGMPIEEVFGRVPDRLQLFSECWDRTLAGESF
VQLQSLTTDGDIGWFETSYGSLAGEDGRPCGGFHIVRDVTDRVRAEESGRLQAEKLAKAVETLTEANAELERFAFVASHD
LQEPLRTVACFAQLVERDYGEGLDDRGRQYLELVTGGAIRMHEMVNDLLAYSRTSRSEGRIERVSAATACQSALNNLREA
IDSSGAEITVAPLPEVDADPVMLIQVFQNLVGNAVKYRKEGLVPHIQVSAEQAGRYWQFSVADNGIGFDPKEQDVFELFR
RLHPHSSYAGTGVGLAICKRIVNRLGGHIWVESTPGAGSVFRFTLPLGEESPPAPAPV

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=212, Percent_Identity=32.0754716981132, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788549, Length=401, Percent_Identity=26.1845386533666, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI145693157, Length=272, Percent_Identity=26.8382352941176, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI48994928, Length=297, Percent_Identity=26.2626262626263, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789149, Length=260, Percent_Identity=27.3076923076923, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87081816, Length=310, Percent_Identity=26.7741935483871, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788713, Length=268, Percent_Identity=23.8805970149254, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790436, Length=227, Percent_Identity=28.6343612334802, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790346, Length=229, Percent_Identity=26.6375545851528, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50562; Mature: 50562

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVSWRITGIYAAVGLGWIFLSSLAVWIGVGEPPGIASLLELGKGCVFILVTALMLLVLL
CCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHH
RRWETELNRRGAALAESNRELSEVNTRLSGIMRGSQDLIAAWDRDKRLTAFNPRYQAVCW
HHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEECCCCHHHHHH
NFFECDVKIGMPIEEVFGRVPDRLQLFSECWDRTLAGESFVQLQSLTTDGDIGWFETSYG
HHEEECEEECCCHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEECCCC
SLAGEDGRPCGGFHIVRDVTDRVRAEESGRLQAEKLAKAVETLTEANAELERFAFVASHD
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQEPLRTVACFAQLVERDYGEGLDDRGRQYLELVTGGAIRMHEMVNDLLAYSRTSRSEGR
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCH
IERVSAATACQSALNNLREAIDSSGAEITVAPLPEVDADPVMLIQVFQNLVGNAVKYRKE
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GLVPHIQVSAEQAGRYWQFSVADNGIGFDPKEQDVFELFRRLHPHSSYAGTGVGLAICKR
CCCCEEEEEHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
IVNRLGGHIWVESTPGAGSVFRFTLPLGEESPPAPAPV
HHHHCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MKVSWRITGIYAAVGLGWIFLSSLAVWIGVGEPPGIASLLELGKGCVFILVTALMLLVLL
CCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHH
RRWETELNRRGAALAESNRELSEVNTRLSGIMRGSQDLIAAWDRDKRLTAFNPRYQAVCW
HHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEECCCCHHHHHH
NFFECDVKIGMPIEEVFGRVPDRLQLFSECWDRTLAGESFVQLQSLTTDGDIGWFETSYG
HHEEECEEECCCHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEECCCC
SLAGEDGRPCGGFHIVRDVTDRVRAEESGRLQAEKLAKAVETLTEANAELERFAFVASHD
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQEPLRTVACFAQLVERDYGEGLDDRGRQYLELVTGGAIRMHEMVNDLLAYSRTSRSEGR
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCH
IERVSAATACQSALNNLREAIDSSGAEITVAPLPEVDADPVMLIQVFQNLVGNAVKYRKE
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GLVPHIQVSAEQAGRYWQFSVADNGIGFDPKEQDVFELFRRLHPHSSYAGTGVGLAICKR
CCCCEEEEEHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
IVNRLGGHIWVESTPGAGSVFRFTLPLGEESPPAPAPV
HHHHCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]