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The map label for this gene is aphA [H]

Identifier: 83311105

GI number: 83311105

Start: 2177093

End: 2179357

Strand: Reverse

Name: aphA [H]

Synonym: amb2006

Alternate gene names: 83311105

Gene position: 2179357-2177093 (Counterclockwise)

Preceding gene: 83311112

Following gene: 83311104

Centisome position: 43.88

GC content: 63.53

Gene sequence:

>2265_bases
GTGAGCGACGGGCTCTCTGTTTCAGGCGAGATTCCCACCCTTGCCGACGTAACCGCCAAGGTCGTGCGTTACGCCGCCGC
CGGGCTGTTCAGCTGGAGTCTTCTGCTGGGAGGCTCGCTGGCCTGGAATATCGCCAAGCAACGGGAGATCACCCTGGAGC
TGGCGACCAATACCGCCCAAGCCAATTTCAACAAGGACGTGGCCTATCGCCTGTGGGCGTCGTCCCATGGCGGCGTCTAT
GTGGAGCCCGATGCCAAGACGCCACCCAGCCCGTGGATGGCCCACCTGCCCGACCGCGACCTGATCGCCAATGACGGGCG
CAAGCTGACCTTGATGAACCCCGCCTACATGCTGCGGCAGATGATGCAGGACCATGGCGAGTTGTACGGCATCAAGGGGC
GCATCGTCGGCATCGTCACCCTCAATTCCGACAACACCGCGGATCCGTGGGAGGCCGAGGCCATCCGGCAGTTCGCCGCC
GGAACCAAATCCGAGGTGATGGAGGTTTCCGATATCGACGGAAAGCCCTTCCTGCGCCTGTTCAAGCCGTTCCGGATGGA
GCCCAGTTGCCAGAAATGCCACGGCCATCTCGGCTTTCAGGACGGCGAAGTGCGCGGCGGCATCGGTGTTTCGGTGCCAT
TGGCGCCCTATCTGACCGGCGAAGCGAACGTTGTCCGGACCATGGCCACCACCCACGGCGCCATCTGGGGATTGGGCATG
CTGGCCATCGGCTGGATCGCCCGGCGCAGCCATTCCCGCCTAGCCGCCAACGCCAGGATGACCCGGGCGCTTCACGACAG
CGAAAAGCATTACCGCGCCATCGTCGAGACCTCTTCCGATGGATTTTGGATGACAGACAACCGGGGGCAGCTCCTGGAGG
TCAACCACGCCTATGCCGCCCGCTCGGGGTACAGTCGGGAGCAATTGCTGTCCATGTCCATCCAGGATCTGGAAGCCATC
GAGACCGATGACGCCACCCACGCCCGCATCGCCGCCGTCATGGCCGGACAGGACCTGCGCTTCGAAACCCGCCATCGCAC
CCGGAATGGCGAGATCTGGGACGTGGAGGTCAGCACCTCGTATTTTGCCGGCGGCGACGGGCGGCTGTTCGTCTTCCTGC
GCGACATCTCCGAACGCAAGCGCGACGAGCGCGTCCTGGCGGAAAGCGAACGGCGGTTCCGTGAGATGGCCGAGACCATC
GATCAGGTATTCTACGTCGCCGACCAGGATTACAGCCGCTTCCACTACATCAGCCCGGCCTTCCTCCGCCTTTGGGGACA
CGCCCCCGAGGTTCTCATGGCCGAGCCCTCCTTGTGGCGCGATTGGGTCCACCCCGAAGACCGCGACGGCGTGATGAACC
TCTTGGCCGCCCGGATCGGATCGGGCGAGTACGCCGCCGACTTCCGGATCATCCGGCCAGATGGCGAGATCGTCTGGCTG
CACGCCAAGGCCTTCGAGGTGGCCAATCCGACCTCTGGCCAGCCCTATGTCCTGGGCTTCCACACCGATATCACCATGGC
CAAATCCATCGAGGCCGAACTGCGCGACAAGAATCAGGCCCTGGAACGGTCCAACGCCGAACTGGAGGCCTATGCCTATG
TGGCCTCGCACGACCTGCGCGAGCCGCTGCGCAACATCACGGCCTTCTCCACCTTGCTGAGGCGACGCCTGGAGGGCCGC
CTGGACGACGAGGAGCAGGAGTTCCTGAAAATCGTCACTGATGCCGCCAACCGCATGGATTGCCTGGTCCGCGATCTGCT
GGAACTCAGCCGCATCGGGCGAAACGAGCGCGACATGCACCTGGTCTCCTTGTCAGAGTTGATGCAGGCGGCAAAAAGCA
GCCTGCGCAGCCAGATGGAGGCCGCCCAGGCCGATATTTCCATCACCTCGCCCCTGCCCGTGATCATGGGCAATGATGAC
GAGCTTTACCGCGTGCTGCTCAACCTGTTCGGCAACGCGATCAAATATCGGGGAGAGGGGCCGGTGCACATCGCCGTTCA
TTGCGAGGCCGAGGGGCCCGAATTGTGGAGAATGACCATCGCCGACAACGGCATCGGAATGGAATTGGGCAAAGGCTATG
AAGAGCGGATCTTCGGCCTGTTCCAACGCCTGCACCAGCGCGACGAGTATGGCGGCGGAACAGGAATCGGCCTGCCGGTC
TGCCGCAAGATCATCGAGCGCCACGGCGGCCGCATCTGGGCCGAAACCGATGGCCCCGGCAAGGGCACCCGCATGATATT
CGTCCTGCCGAAACTGCCGGACTGA

Upstream 100 bases:

>100_bases
CGGCAGTCAGGTTTCGTTACCAGATGCCATGATACCTCATGCACGCATATTTGTTAAAATCGGCCTGTCGGCTCCGGCCA
GGGCCAAATGGGGGACATTT

Downstream 100 bases:

>100_bases
CGCATTCACTGTGCCACAAGAACAACTTTCTGGTAGCCTCAGCATCCAAAGGCGTCCACCAATCCGAGGGAATTCATCGC
ATTGAAAGTTTCCTGGCGCA

Product: Signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 754; Mature: 753

Protein sequence:

>754_residues
MSDGLSVSGEIPTLADVTAKVVRYAAAGLFSWSLLLGGSLAWNIAKQREITLELATNTAQANFNKDVAYRLWASSHGGVY
VEPDAKTPPSPWMAHLPDRDLIANDGRKLTLMNPAYMLRQMMQDHGELYGIKGRIVGIVTLNSDNTADPWEAEAIRQFAA
GTKSEVMEVSDIDGKPFLRLFKPFRMEPSCQKCHGHLGFQDGEVRGGIGVSVPLAPYLTGEANVVRTMATTHGAIWGLGM
LAIGWIARRSHSRLAANARMTRALHDSEKHYRAIVETSSDGFWMTDNRGQLLEVNHAYAARSGYSREQLLSMSIQDLEAI
ETDDATHARIAAVMAGQDLRFETRHRTRNGEIWDVEVSTSYFAGGDGRLFVFLRDISERKRDERVLAESERRFREMAETI
DQVFYVADQDYSRFHYISPAFLRLWGHAPEVLMAEPSLWRDWVHPEDRDGVMNLLAARIGSGEYAADFRIIRPDGEIVWL
HAKAFEVANPTSGQPYVLGFHTDITMAKSIEAELRDKNQALERSNAELEAYAYVASHDLREPLRNITAFSTLLRRRLEGR
LDDEEQEFLKIVTDAANRMDCLVRDLLELSRIGRNERDMHLVSLSELMQAAKSSLRSQMEAAQADISITSPLPVIMGNDD
ELYRVLLNLFGNAIKYRGEGPVHIAVHCEAEGPELWRMTIADNGIGMELGKGYEERIFGLFQRLHQRDEYGGGTGIGLPV
CRKIIERHGGRIWAETDGPGKGTRMIFVLPKLPD

Sequences:

>Translated_754_residues
MSDGLSVSGEIPTLADVTAKVVRYAAAGLFSWSLLLGGSLAWNIAKQREITLELATNTAQANFNKDVAYRLWASSHGGVY
VEPDAKTPPSPWMAHLPDRDLIANDGRKLTLMNPAYMLRQMMQDHGELYGIKGRIVGIVTLNSDNTADPWEAEAIRQFAA
GTKSEVMEVSDIDGKPFLRLFKPFRMEPSCQKCHGHLGFQDGEVRGGIGVSVPLAPYLTGEANVVRTMATTHGAIWGLGM
LAIGWIARRSHSRLAANARMTRALHDSEKHYRAIVETSSDGFWMTDNRGQLLEVNHAYAARSGYSREQLLSMSIQDLEAI
ETDDATHARIAAVMAGQDLRFETRHRTRNGEIWDVEVSTSYFAGGDGRLFVFLRDISERKRDERVLAESERRFREMAETI
DQVFYVADQDYSRFHYISPAFLRLWGHAPEVLMAEPSLWRDWVHPEDRDGVMNLLAARIGSGEYAADFRIIRPDGEIVWL
HAKAFEVANPTSGQPYVLGFHTDITMAKSIEAELRDKNQALERSNAELEAYAYVASHDLREPLRNITAFSTLLRRRLEGR
LDDEEQEFLKIVTDAANRMDCLVRDLLELSRIGRNERDMHLVSLSELMQAAKSSLRSQMEAAQADISITSPLPVIMGNDD
ELYRVLLNLFGNAIKYRGEGPVHIAVHCEAEGPELWRMTIADNGIGMELGKGYEERIFGLFQRLHQRDEYGGGTGIGLPV
CRKIIERHGGRIWAETDGPGKGTRMIFVLPKLPD
>Mature_753_residues
SDGLSVSGEIPTLADVTAKVVRYAAAGLFSWSLLLGGSLAWNIAKQREITLELATNTAQANFNKDVAYRLWASSHGGVYV
EPDAKTPPSPWMAHLPDRDLIANDGRKLTLMNPAYMLRQMMQDHGELYGIKGRIVGIVTLNSDNTADPWEAEAIRQFAAG
TKSEVMEVSDIDGKPFLRLFKPFRMEPSCQKCHGHLGFQDGEVRGGIGVSVPLAPYLTGEANVVRTMATTHGAIWGLGML
AIGWIARRSHSRLAANARMTRALHDSEKHYRAIVETSSDGFWMTDNRGQLLEVNHAYAARSGYSREQLLSMSIQDLEAIE
TDDATHARIAAVMAGQDLRFETRHRTRNGEIWDVEVSTSYFAGGDGRLFVFLRDISERKRDERVLAESERRFREMAETID
QVFYVADQDYSRFHYISPAFLRLWGHAPEVLMAEPSLWRDWVHPEDRDGVMNLLAARIGSGEYAADFRIIRPDGEIVWLH
AKAFEVANPTSGQPYVLGFHTDITMAKSIEAELRDKNQALERSNAELEAYAYVASHDLREPLRNITAFSTLLRRRLEGRL
DDEEQEFLKIVTDAANRMDCLVRDLLELSRIGRNERDMHLVSLSELMQAAKSSLRSQMEAAQADISITSPLPVIMGNDDE
LYRVLLNLFGNAIKYRGEGPVHIAVHCEAEGPELWRMTIADNGIGMELGKGYEERIFGLFQRLHQRDEYGGGTGIGLPVC
RKIIERHGGRIWAETDGPGKGTRMIFVLPKLPD

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=286, Percent_Identity=26.2237762237762, Blast_Score=91, Evalue=4e-19,
Organism=Escherichia coli, GI1790346, Length=238, Percent_Identity=31.5126050420168, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1786912, Length=219, Percent_Identity=31.0502283105023, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1788713, Length=266, Percent_Identity=25.5639097744361, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786600, Length=264, Percent_Identity=28.030303030303, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1788381, Length=275, Percent_Identity=24.3636363636364, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790436, Length=217, Percent_Identity=26.2672811059908, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788549, Length=222, Percent_Identity=26.5765765765766, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI87081816, Length=244, Percent_Identity=26.2295081967213, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1789149, Length=263, Percent_Identity=25.0950570342205, Blast_Score=66, Evalue=9e-12,
Organism=Escherichia coli, GI145693157, Length=257, Percent_Identity=24.9027237354086, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 84558; Mature: 84427

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDGLSVSGEIPTLADVTAKVVRYAAAGLFSWSLLLGGSLAWNIAKQREITLELATNTAQ
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEEEECCCCC
ANFNKDVAYRLWASSHGGVYVEPDAKTPPSPWMAHLPDRDLIANDGRKLTLMNPAYMLRQ
CCCCCCEEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHH
MMQDHGELYGIKGRIVGIVTLNSDNTADPWEAEAIRQFAAGTKSEVMEVSDIDGKPFLRL
HHHHCCCEEEECEEEEEEEEECCCCCCCCHHHHHHHHHHCCCHHHCEEEECCCCCHHHHH
FKPFRMEPSCQKCHGHLGFQDGEVRGGIGVSVPLAPYLTGEANVVRTMATTHGAIWGLGM
HHHCCCCCCHHHHCCCCCCCCCCCCCCCEECCCCCCEECCCCHHHHHHHHHHHHHHHHHH
LAIGWIARRSHSRLAANARMTRALHDSEKHYRAIVETSSDGFWMTDNRGQLLEVNHAYAA
HHHHHHHHHCCHHHHHHHHHHHHHHCCHHHEEEEEEECCCCEEEECCCCCEEEECCHHHH
RSGYSREQLLSMSIQDLEAIETDDATHARIAAVMAGQDLRFETRHRTRNGEIWDVEVSTS
CCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEHHHHCCCCCCEEEEEECCE
YFAGGDGRLFVFLRDISERKRDERVLAESERRFREMAETIDQVFYVADQDYSRFHYISPA
EEECCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEECCHH
FLRLWGHAPEVLMAEPSLWRDWVHPEDRDGVMNLLAARIGSGEYAADFRIIRPDGEIVWL
HHHHHCCCCCEEEECCHHHHHCCCCCCCHHHHHHHHHHCCCCCEEECEEEECCCCCEEEE
HAKAFEVANPTSGQPYVLGFHTDITMAKSIEAELRDKNQALERSNAELEAYAYVASHDLR
EEEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHH
EPLRNITAFSTLLRRRLEGRLDDEEQEFLKIVTDAANRMDCLVRDLLELSRIGRNERDMH
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
LVSLSELMQAAKSSLRSQMEAAQADISITSPLPVIMGNDDELYRVLLNLFGNAIKYRGEG
HHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCEEECCCHHHHHHHHHHHCCCEEECCCC
PVHIAVHCEAEGPELWRMTIADNGIGMELGKGYEERIFGLFQRLHQRDEYGGGTGIGLPV
CEEEEEEEECCCCCEEEEEEECCCCCCHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHH
CRKIIERHGGRIWAETDGPGKGTRMIFVLPKLPD
HHHHHHHCCCEEEEECCCCCCCCEEEEEECCCCC
>Mature Secondary Structure 
SDGLSVSGEIPTLADVTAKVVRYAAAGLFSWSLLLGGSLAWNIAKQREITLELATNTAQ
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEEEECCCCC
ANFNKDVAYRLWASSHGGVYVEPDAKTPPSPWMAHLPDRDLIANDGRKLTLMNPAYMLRQ
CCCCCCEEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHH
MMQDHGELYGIKGRIVGIVTLNSDNTADPWEAEAIRQFAAGTKSEVMEVSDIDGKPFLRL
HHHHCCCEEEECEEEEEEEEECCCCCCCCHHHHHHHHHHCCCHHHCEEEECCCCCHHHHH
FKPFRMEPSCQKCHGHLGFQDGEVRGGIGVSVPLAPYLTGEANVVRTMATTHGAIWGLGM
HHHCCCCCCHHHHCCCCCCCCCCCCCCCEECCCCCCEECCCCHHHHHHHHHHHHHHHHHH
LAIGWIARRSHSRLAANARMTRALHDSEKHYRAIVETSSDGFWMTDNRGQLLEVNHAYAA
HHHHHHHHHCCHHHHHHHHHHHHHHCCHHHEEEEEEECCCCEEEECCCCCEEEECCHHHH
RSGYSREQLLSMSIQDLEAIETDDATHARIAAVMAGQDLRFETRHRTRNGEIWDVEVSTS
CCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEHHHHCCCCCCEEEEEECCE
YFAGGDGRLFVFLRDISERKRDERVLAESERRFREMAETIDQVFYVADQDYSRFHYISPA
EEECCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEECCHH
FLRLWGHAPEVLMAEPSLWRDWVHPEDRDGVMNLLAARIGSGEYAADFRIIRPDGEIVWL
HHHHHCCCCCEEEECCHHHHHCCCCCCCHHHHHHHHHHCCCCCEEECEEEECCCCCEEEE
HAKAFEVANPTSGQPYVLGFHTDITMAKSIEAELRDKNQALERSNAELEAYAYVASHDLR
EEEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHH
EPLRNITAFSTLLRRRLEGRLDDEEQEFLKIVTDAANRMDCLVRDLLELSRIGRNERDMH
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
LVSLSELMQAAKSSLRSQMEAAQADISITSPLPVIMGNDDELYRVLLNLFGNAIKYRGEG
HHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCEEECCCHHHHHHHHHHHCCCEEECCCC
PVHIAVHCEAEGPELWRMTIADNGIGMELGKGYEERIFGLFQRLHQRDEYGGGTGIGLPV
CEEEEEEEECCCCCEEEEEEECCCCCCHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHH
CRKIIERHGGRIWAETDGPGKGTRMIFVLPKLPD
HHHHHHHCCCEEEEECCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]