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The map label for this gene is murA

Identifier: 83311081

GI number: 83311081

Start: 2141499

End: 2142797

Strand: Reverse

Name: murA

Synonym: amb1982

Alternate gene names: 83311081

Gene position: 2142797-2141499 (Counterclockwise)

Preceding gene: 83311085

Following gene: 83311079

Centisome position: 43.14

GC content: 67.98

Gene sequence:

>1299_bases
ATGGACAGGATCCGCATTGTCGGCGGGACGCCGCTCAAGGGCACCATCACCATCGGCGGCGCCAAGAACGCCGCCCTGGC
GCTGATGCCCGCCTGCCTGCTGACCGAGGAAACCCTGGCGCTGTCCAACCTGCCCCATCTGGTGGATATCACCACCATGG
CCAATTTGTTGGCCCAGCACGGGGTGACCATGGCGTTGAACGGTGACGCCGCCAATGGCGGACATACGGGCCGCGTCCTG
GAGCTGACCGCCGCCCATATCGGCAACACCACGGCGCCTTATGATCTGGTGCGCAAGATGCGCGCTTCGGTGCTGGTGCT
GGGGCCGCTGCTGGCCCGCTTCGGCGAGGCCCGGGTGTCGCTTCCCGGCGGCTGCGCCATCGGCACCCGCCCCGTCGACC
TGCACCTGAAGGCGCTGGAGCAGATGGGCGCCAAGATCGAGCTGGACGGCGGCTACATCATCGCCTCCGTCCAAGGCCGC
CTCAAGGGCGCCCACGTCATCTTCCCGCAGATCACCGTGGGCGGCACCGAGAACATCCTGATGGCCGCCACCCTGGCCGA
GGGCGAGACGGTGATCGCCAACGCCGCGCGCGAGCCCGAGATCACCGATCTGGCCGAATGCCTGGTGGCCATGGGCGCCA
AGATCGAGGGCATCGGCACCGGCACCCTGAAGGTCCAGGGCGTCGAGCGCCTGCACGGCGCCGAATACTCCGTGGTCCCC
GACCGCATCGAGACCGGCACCTATGCGGTGGCCGCCGCCATCACCCGAGGCGATATCGAGCTGGTGGGCGCCCGCTTCGA
TCTGATGGAATCCGTCAACAAGGTGCTGACGGAATGCGGCGTCCACGTGGAGGAAACGCCGCGTGGCATGCGGGTGCGCG
CCGATCAGGGCGAGATCACCGGCGTCGACATCATGACCGAGCCCTATCCCGGCTTTCCCACCGACATGCAGGCCCAGTTG
ATGGCCCTGATGTCCACGGCCAAGGGCGCCTCCATGATCACCGAGACCATCTTCGAGAACCGCTTCATGCATGTTCCCGA
GATGACCCGCATGGGGGCGCGCATCAACGTCCACGGCTCGTCGGCCATCGTGCGCGGCGCTCCCAAGCTGTCGGGCGCCC
AGGTGATGGCCACCGATCTGCGCGCCTCGGTCTCCCTGGTCCTGGCCGCCCTGGCCGCCGAGGGCGAGACCATCGTCAAC
CGCGTCTACCACCTGGACCGCGGCTACGAGCGGGTCGAGGAAAAGCTGGCCGCCTGCGGCGCGAAGATCGAACGCCTCAA
GGACGGCGTGGCGGAGTAG

Upstream 100 bases:

>100_bases
TATAATTTGATTCTGACCTCGCCTCTCCCCCTCCCCTTGACCGGGGGAACTCGGACGGGCTAAAGGGTGCCTTTGATTCC
CCTTCACTCAAGGACCAAGC

Downstream 100 bases:

>100_bases
CCCCCCTTACTTGTGCACCAGGGCCACCAGTTTGGCGATCCAGCCCAGCTTCCAGGCCAGGGCCAGCGCCGCCAGCACCA
CGCCGGCGAACACCGCCGAA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MDRIRIVGGTPLKGTITIGGAKNAALALMPACLLTEETLALSNLPHLVDITTMANLLAQHGVTMALNGDAANGGHTGRVL
ELTAAHIGNTTAPYDLVRKMRASVLVLGPLLARFGEARVSLPGGCAIGTRPVDLHLKALEQMGAKIELDGGYIIASVQGR
LKGAHVIFPQITVGGTENILMAATLAEGETVIANAAREPEITDLAECLVAMGAKIEGIGTGTLKVQGVERLHGAEYSVVP
DRIETGTYAVAAAITRGDIELVGARFDLMESVNKVLTECGVHVEETPRGMRVRADQGEITGVDIMTEPYPGFPTDMQAQL
MALMSTAKGASMITETIFENRFMHVPEMTRMGARINVHGSSAIVRGAPKLSGAQVMATDLRASVSLVLAALAAEGETIVN
RVYHLDRGYERVEEKLAACGAKIERLKDGVAE

Sequences:

>Translated_432_residues
MDRIRIVGGTPLKGTITIGGAKNAALALMPACLLTEETLALSNLPHLVDITTMANLLAQHGVTMALNGDAANGGHTGRVL
ELTAAHIGNTTAPYDLVRKMRASVLVLGPLLARFGEARVSLPGGCAIGTRPVDLHLKALEQMGAKIELDGGYIIASVQGR
LKGAHVIFPQITVGGTENILMAATLAEGETVIANAAREPEITDLAECLVAMGAKIEGIGTGTLKVQGVERLHGAEYSVVP
DRIETGTYAVAAAITRGDIELVGARFDLMESVNKVLTECGVHVEETPRGMRVRADQGEITGVDIMTEPYPGFPTDMQAQL
MALMSTAKGASMITETIFENRFMHVPEMTRMGARINVHGSSAIVRGAPKLSGAQVMATDLRASVSLVLAALAAEGETIVN
RVYHLDRGYERVEEKLAACGAKIERLKDGVAE
>Mature_432_residues
MDRIRIVGGTPLKGTITIGGAKNAALALMPACLLTEETLALSNLPHLVDITTMANLLAQHGVTMALNGDAANGGHTGRVL
ELTAAHIGNTTAPYDLVRKMRASVLVLGPLLARFGEARVSLPGGCAIGTRPVDLHLKALEQMGAKIELDGGYIIASVQGR
LKGAHVIFPQITVGGTENILMAATLAEGETVIANAAREPEITDLAECLVAMGAKIEGIGTGTLKVQGVERLHGAEYSVVP
DRIETGTYAVAAAITRGDIELVGARFDLMESVNKVLTECGVHVEETPRGMRVRADQGEITGVDIMTEPYPGFPTDMQAQL
MALMSTAKGASMITETIFENRFMHVPEMTRMGARINVHGSSAIVRGAPKLSGAQVMATDLRASVSLVLAALAAEGETIVN
RVYHLDRGYERVEEKLAACGAKIERLKDGVAE

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=427, Percent_Identity=52.6932084309134, Blast_Score=440, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_MAGSA (Q2W5T9)

Other databases:

- EMBL:   AP007255
- RefSeq:   YP_421345.1
- HSSP:   P33038
- ProteinModelPortal:   Q2W5T9
- SMR:   Q2W5T9
- STRING:   Q2W5T9
- GeneID:   3804518
- GenomeReviews:   AP007255_GR
- KEGG:   mag:amb1982
- NMPDR:   fig|342108.5.peg.1740
- eggNOG:   COG0766
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- PhylomeDB:   Q2W5T9
- ProtClustDB:   PRK09369
- BioCyc:   MMAG342108:AMB1982-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 45543; Mature: 45543

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: ACT_SITE 125-125

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRIRIVGGTPLKGTITIGGAKNAALALMPACLLTEETLALSNLPHLVDITTMANLLAQH
CCCEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
GVTMALNGDAANGGHTGRVLELTAAHIGNTTAPYDLVRKMRASVLVLGPLLARFGEARVS
CEEEEECCCCCCCCCCCEEEEEEEHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LPGGCAIGTRPVDLHLKALEQMGAKIELDGGYIIASVQGRLKGAHVIFPQITVGGTENIL
CCCCCEECCCCHHHHHHHHHHCCCEEEECCCEEEEEECCCCCCCEEEEEEEEECCCCCEE
MAATLAEGETVIANAAREPEITDLAECLVAMGAKIEGIGTGTLKVQGVERLHGAEYSVVP
EEEEECCCCEEEECCCCCCCHHHHHHHHHHCCCEEEEECCCEEEEECHHHHCCCCCEECC
DRIETGTYAVAAAITRGDIELVGARFDLMESVNKVLTECGVHVEETPRGMRVRADQGEIT
CCCCCCCEEEEEEEECCCEEEEEHHHHHHHHHHHHHHHCCCEEECCCCCCEEECCCCCEE
GVDIMTEPYPGFPTDMQAQLMALMSTAKGASMITETIFENRFMHVPEMTRMGARINVHGS
EEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHCCCEEEECCC
SAIVRGAPKLSGAQVMATDLRASVSLVLAALAAEGETIVNRVYHLDRGYERVEEKLAACG
CEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHH
AKIERLKDGVAE
HHHHHHHCCCCC
>Mature Secondary Structure
MDRIRIVGGTPLKGTITIGGAKNAALALMPACLLTEETLALSNLPHLVDITTMANLLAQH
CCCEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
GVTMALNGDAANGGHTGRVLELTAAHIGNTTAPYDLVRKMRASVLVLGPLLARFGEARVS
CEEEEECCCCCCCCCCCEEEEEEEHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LPGGCAIGTRPVDLHLKALEQMGAKIELDGGYIIASVQGRLKGAHVIFPQITVGGTENIL
CCCCCEECCCCHHHHHHHHHHCCCEEEECCCEEEEEECCCCCCCEEEEEEEEECCCCCEE
MAATLAEGETVIANAAREPEITDLAECLVAMGAKIEGIGTGTLKVQGVERLHGAEYSVVP
EEEEECCCCEEEECCCCCCCHHHHHHHHHHCCCEEEEECCCEEEEECHHHHCCCCCEECC
DRIETGTYAVAAAITRGDIELVGARFDLMESVNKVLTECGVHVEETPRGMRVRADQGEIT
CCCCCCCEEEEEEEECCCEEEEEHHHHHHHHHHHHHHHCCCEEECCCCCCEEECCCCCEE
GVDIMTEPYPGFPTDMQAQLMALMSTAKGASMITETIFENRFMHVPEMTRMGARINVHGS
EEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHCCCEEEECCC
SAIVRGAPKLSGAQVMATDLRASVSLVLAALAAEGETIVNRVYHLDRGYERVEEKLAACG
CEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHH
AKIERLKDGVAE
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA