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The map label for this gene is dctD [H]

Identifier: 83310755

GI number: 83310755

Start: 1794388

End: 1795725

Strand: Reverse

Name: dctD [H]

Synonym: amb1656

Alternate gene names: 83310755

Gene position: 1795725-1794388 (Counterclockwise)

Preceding gene: 83310758

Following gene: 83310753

Centisome position: 36.15

GC content: 69.96

Gene sequence:

>1338_bases
ATGAGCGCCGGTCAGATTCTGTTCGTCGACGACGAAGAACCCATGCGGATCGCCGTCAAGCAATGGCTTGGACTGGCGGG
ATTCGACGTGACCGTCCTGGCCCGGCCCGAAGGGGCGTTGGGCCGGCTGTCCCGGGACTTTCCCGGCATCCTGGTCAGCG
ACGTGCGCATGCCGGGCCTGGACGGCATCGGGCTTCTGAAGGCGGCCCAGGCCCAGGACCCCGATCTGCCGGTAATCCTG
GTCACCGGCCACGGCGATATTCCGCTGGCGGTGGAAGCCATGCGCGAAGGCGCCTACGACTTCATCGAAAAGCCCTTCGC
CCCCGAGCGTTTGGCCCAGGCGGTGGGCCGCGCCTGCGAGAAGCGGCGGCTGGTGCTGGAAAATCGCCGCCTGCGCGCCC
TGGGGGCCGGCGACGACATGGCGCGGCGCCTGATCGGCCCGTCCCAGGCCATGGAGAACGTCCGCGCCCAGGTCCGAGAA
CTGGCGCCGCTGCCGCTCAACGTGGTGATCTTCGGCGATACCGGCTGCGGCAAGGAACTGGTGGCCCGCTGCCTGCACGA
TTGCGGCCCCCGCGCCGCCCGGCCCTTCGTGGCGGTCAACTGCGCCGCCATCCCCGAAACCATGTTCGAAAGCGAGTTCT
TCGGCCACGAGGCCGGGGCCTTCACCGGCGCCGCCCAGCGCCGGGCCGGCAAGGTCGAGCACGCCCATGGCGGCACCTTG
TTCCTGGACGAGGTGGAAAGCATGCCGCTGGCGCTTCAGGCCAAGCTGCTGCGCGTGCTGCAGGAACGCTGCATCGAACC
CCTGGGCGGCAACCGCACCATTCCCGTCGACCTGCGGGTGATCACCGCCGCCAAGGCCGATCTGCTGGCCGAAGTCCGCG
CCGGCCGCTTCCGCGAGGATCTGTATTACCGCCTGCATGTGGCGGAAATCCGCTTGCCCCCCCTGGCCGAGCGCCGCGAG
GACATCGTCGCCCTGTTCGAGAGCTTCGCCGCCCTGGCCGCCAATGCCCACGGCCGCACGCCCCCGACCCTGACCGAAGG
CAATGTGCAGGCCCTGCTGGCCCATGACTGGCCGGGCAATGTGCGGGAATTGCGCAACGAGGCGGAACGCTTCGCCCTGG
GCCTGGGGCTGCGGGCGGCGGCGCCGGTCGCGGCGGAAGCCCAGGGGGATGGATTGCAGGCCAGCGTCGCCCTGTTCGAG
CGCCAGCGCATCGAGGCGGCCTTCATTCAGGCCCAGGGGGATGTCGCCGAGGTCATGCGCCTGCTGGACCTGCCGCGCCG
GACGCTCAACGAGAAGATGGCCAAGTACGGCATCGACCGCCGTCGCTTCCTGGGCTGA

Upstream 100 bases:

>100_bases
CGGAGGGTGGAGCGGCGGGCCGGGTCATGCCCTCAAGGCAAACACGGCAGCCCCACCCCCGGCAATTTGATTTTCATCCC
GGCTGCGGTATGGTCCTGAC

Downstream 100 bases:

>100_bases
AAAGGCTCGCCGGTCGCCTGTGACCGGCGAGCCCCTCCCTCATTTGGTATTAACGGTCAGCGACTTGCACGTGGCGTAGG
AATTGGTCGACTTCGAGCAG

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MSAGQILFVDDEEPMRIAVKQWLGLAGFDVTVLARPEGALGRLSRDFPGILVSDVRMPGLDGIGLLKAAQAQDPDLPVIL
VTGHGDIPLAVEAMREGAYDFIEKPFAPERLAQAVGRACEKRRLVLENRRLRALGAGDDMARRLIGPSQAMENVRAQVRE
LAPLPLNVVIFGDTGCGKELVARCLHDCGPRAARPFVAVNCAAIPETMFESEFFGHEAGAFTGAAQRRAGKVEHAHGGTL
FLDEVESMPLALQAKLLRVLQERCIEPLGGNRTIPVDLRVITAAKADLLAEVRAGRFREDLYYRLHVAEIRLPPLAERRE
DIVALFESFAALAANAHGRTPPTLTEGNVQALLAHDWPGNVRELRNEAERFALGLGLRAAAPVAAEAQGDGLQASVALFE
RQRIEAAFIQAQGDVAEVMRLLDLPRRTLNEKMAKYGIDRRRFLG

Sequences:

>Translated_445_residues
MSAGQILFVDDEEPMRIAVKQWLGLAGFDVTVLARPEGALGRLSRDFPGILVSDVRMPGLDGIGLLKAAQAQDPDLPVIL
VTGHGDIPLAVEAMREGAYDFIEKPFAPERLAQAVGRACEKRRLVLENRRLRALGAGDDMARRLIGPSQAMENVRAQVRE
LAPLPLNVVIFGDTGCGKELVARCLHDCGPRAARPFVAVNCAAIPETMFESEFFGHEAGAFTGAAQRRAGKVEHAHGGTL
FLDEVESMPLALQAKLLRVLQERCIEPLGGNRTIPVDLRVITAAKADLLAEVRAGRFREDLYYRLHVAEIRLPPLAERRE
DIVALFESFAALAANAHGRTPPTLTEGNVQALLAHDWPGNVRELRNEAERFALGLGLRAAAPVAAEAQGDGLQASVALFE
RQRIEAAFIQAQGDVAEVMRLLDLPRRTLNEKMAKYGIDRRRFLG
>Mature_444_residues
SAGQILFVDDEEPMRIAVKQWLGLAGFDVTVLARPEGALGRLSRDFPGILVSDVRMPGLDGIGLLKAAQAQDPDLPVILV
TGHGDIPLAVEAMREGAYDFIEKPFAPERLAQAVGRACEKRRLVLENRRLRALGAGDDMARRLIGPSQAMENVRAQVREL
APLPLNVVIFGDTGCGKELVARCLHDCGPRAARPFVAVNCAAIPETMFESEFFGHEAGAFTGAAQRRAGKVEHAHGGTLF
LDEVESMPLALQAKLLRVLQERCIEPLGGNRTIPVDLRVITAAKADLLAEVRAGRFREDLYYRLHVAEIRLPPLAERRED
IVALFESFAALAANAHGRTPPTLTEGNVQALLAHDWPGNVRELRNEAERFALGLGLRAAAPVAAEAQGDGLQASVALFER
QRIEAAFIQAQGDVAEVMRLLDLPRRTLNEKMAKYGIDRRRFLG

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. When activated by dctB acts in conjunction with sigma-54 to activate the transcription of dctA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=453, Percent_Identity=38.8520971302428, Blast_Score=296, Evalue=2e-81,
Organism=Escherichia coli, GI1790299, Length=473, Percent_Identity=36.7864693446089, Blast_Score=279, Evalue=2e-76,
Organism=Escherichia coli, GI1790437, Length=441, Percent_Identity=37.18820861678, Blast_Score=271, Evalue=6e-74,
Organism=Escherichia coli, GI1788905, Length=452, Percent_Identity=35.1769911504425, Blast_Score=265, Evalue=6e-72,
Organism=Escherichia coli, GI87082117, Length=371, Percent_Identity=40.9703504043127, Blast_Score=234, Evalue=9e-63,
Organism=Escherichia coli, GI1789087, Length=351, Percent_Identity=43.019943019943, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1789233, Length=228, Percent_Identity=46.4912280701754, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI87082152, Length=317, Percent_Identity=39.4321766561514, Blast_Score=205, Evalue=5e-54,
Organism=Escherichia coli, GI1786524, Length=247, Percent_Identity=46.5587044534413, Blast_Score=202, Evalue=5e-53,
Organism=Escherichia coli, GI87081872, Length=229, Percent_Identity=45.8515283842795, Blast_Score=192, Evalue=5e-50,
Organism=Escherichia coli, GI1787583, Length=330, Percent_Identity=35.1515151515151, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI87081858, Length=300, Percent_Identity=33.3333333333333, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1789828, Length=224, Percent_Identity=36.1607142857143, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1789809, Length=107, Percent_Identity=32.7102803738318, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 48552; Mature: 48420

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAGQILFVDDEEPMRIAVKQWLGLAGFDVTVLARPEGALGRLSRDFPGILVSDVRMPGL
CCCCCEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCHHHHHCCCCCCEEEECCCCCCC
DGIGLLKAAQAQDPDLPVILVTGHGDIPLAVEAMREGAYDFIEKPFAPERLAQAVGRACE
CCCHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHH
KRRLVLENRRLRALGAGDDMARRLIGPSQAMENVRAQVRELAPLPLNVVIFGDTGCGKEL
HHHHHHHCCCEEEECCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHH
VARCLHDCGPRAARPFVAVNCAAIPETMFESEFFGHEAGAFTGAAQRRAGKVEHAHGGTL
HHHHHHHCCCCCCCCEEEEEHHHCCHHHHHHHHCCCCCCCCCCHHHHHCCCCEECCCCEE
FLDEVESMPLALQAKLLRVLQERCIEPLGGNRTIPVDLRVITAAKADLLAEVRAGRFRED
EEEHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEHHHHHHHHHHHHCHHHHH
LYYRLHVAEIRLPPLAERREDIVALFESFAALAANAHGRTPPTLTEGNVQALLAHDWPGN
HHEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCH
VRELRNEAERFALGLGLRAAAPVAAEAQGDGLQASVALFERQRIEAAFIQAQGDVAEVMR
HHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LLDLPRRTLNEKMAKYGIDRRRFLG
HHHCCHHHHHHHHHHHCCCHHHHCC
>Mature Secondary Structure 
SAGQILFVDDEEPMRIAVKQWLGLAGFDVTVLARPEGALGRLSRDFPGILVSDVRMPGL
CCCCEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCHHHHHCCCCCCEEEECCCCCCC
DGIGLLKAAQAQDPDLPVILVTGHGDIPLAVEAMREGAYDFIEKPFAPERLAQAVGRACE
CCCHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHH
KRRLVLENRRLRALGAGDDMARRLIGPSQAMENVRAQVRELAPLPLNVVIFGDTGCGKEL
HHHHHHHCCCEEEECCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHH
VARCLHDCGPRAARPFVAVNCAAIPETMFESEFFGHEAGAFTGAAQRRAGKVEHAHGGTL
HHHHHHHCCCCCCCCEEEEEHHHCCHHHHHHHHCCCCCCCCCCHHHHHCCCCEECCCCEE
FLDEVESMPLALQAKLLRVLQERCIEPLGGNRTIPVDLRVITAAKADLLAEVRAGRFRED
EEEHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEHHHHHHHHHHHHCHHHHH
LYYRLHVAEIRLPPLAERREDIVALFESFAALAANAHGRTPPTLTEGNVQALLAHDWPGN
HHEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCH
VRELRNEAERFALGLGLRAAAPVAAEAQGDGLQASVALFERQRIEAAFIQAQGDVAEVMR
HHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LLDLPRRTLNEKMAKYGIDRRRFLG
HHHCCHHHHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431 [H]