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The map label for this gene is hypB [H]

Identifier: 83310741

GI number: 83310741

Start: 1780511

End: 1781449

Strand: Reverse

Name: hypB [H]

Synonym: amb1642

Alternate gene names: 83310741

Gene position: 1781449-1780511 (Counterclockwise)

Preceding gene: 83310742

Following gene: 83310740

Centisome position: 35.86

GC content: 63.68

Gene sequence:

>939_bases
ATGTGCACGGTTTGCGGCTGCGGCGACGCCAAGGTGGACGGCCACGCTCATTCCCCCCATTCCCATGACCACGACCATGA
GCACCATCATGGCCATAGCCACGATCACAGCCATGACCATCCCCATGGCCACGACCACCATCATCACGACCACGATTCCG
ACAAAGACATCCATTATGGCCGCGGCATCGCCGGCGTCCATGTGCCGGGCATGAGCCAGAAGCGCATCGTCCAGATCGAG
AAGGACATCCTGTCCCACAACGACGACTTCGCCGGACGCAACCGCGCCTGGCTGGCCGAGCATGGCGTCTTTGCCCTGAA
CCTGGTGTCCAGCCCCGGCTCGGGCAAGACCACCTTGCTGTGTCGCACCGCCGAGGCCTTGAAGGGGCGCTATCCGCTGG
CGGTGATCGAGGGCGACCAGCAGACCAGCTTCGACGCCGACCGCATCCGCGCCACCGGAATTCCCGCCATCCAGGTCAAT
ACCGGCAAGGGCTGCCACCTGGACGCCCATATGGTGGAAAGCGCCATGGCCAAGCTGAACGTTGCCGACGATTCGGTGCT
GTTCATCGAGAATGTGGGCAATCTGGTCTGCCCCGCCGCCTTCGACCTGGGCGAGGCCTACAAGGTGGCGATTCTGTCGG
TGACCGAGGGCGAGGACAAGCCTCTGAAGTATCCCGACATGTTCCATGCCGCCTCCATGATGATCCTCAACAAGACCGAC
CTGCTGCCCCATACCGATTTCGACGTGGAGCGCTGCATCGGCTTTGCCCGCCGCGTCAATCCCGACATCGTGGTGCTCCA
GCTCTCGGCCCGCACCGGCGAGGGCTTCGATGAATGGCTGGCCTGGATCAACGAGGGCCGCAAGCGCATGGTGACGGAGC
GCATCCGCCGCCTGGAAGCCAAGCTGGCCGCCGCCAAGGCGAGTCTGGAGGGTAAGTGA

Upstream 100 bases:

>100_bases
ATGTCACCTCGCGGGTGGACCTCTGCCCCGATTGCGGTGGCGCCAAGCTGGCGGTGACCACGGGCGAGGAAATGCGGATC
AAGGAAATGGAGGTGGAGTG

Downstream 100 bases:

>100_bases
CCTCGGCCATCGCCCAGATCGTCGCCCTGCCCCGCGCCGTGCCGCCGGTGCTGGCCGTCGGCGCCTTTCTTAAGAATGCC
GTCTGCGTGACCAGGGGGGC

Product: Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MCTVCGCGDAKVDGHAHSPHSHDHDHEHHHGHSHDHSHDHPHGHDHHHHDHDSDKDIHYGRGIAGVHVPGMSQKRIVQIE
KDILSHNDDFAGRNRAWLAEHGVFALNLVSSPGSGKTTLLCRTAEALKGRYPLAVIEGDQQTSFDADRIRATGIPAIQVN
TGKGCHLDAHMVESAMAKLNVADDSVLFIENVGNLVCPAAFDLGEAYKVAILSVTEGEDKPLKYPDMFHAASMMILNKTD
LLPHTDFDVERCIGFARRVNPDIVVLQLSARTGEGFDEWLAWINEGRKRMVTERIRRLEAKLAAAKASLEGK

Sequences:

>Translated_312_residues
MCTVCGCGDAKVDGHAHSPHSHDHDHEHHHGHSHDHSHDHPHGHDHHHHDHDSDKDIHYGRGIAGVHVPGMSQKRIVQIE
KDILSHNDDFAGRNRAWLAEHGVFALNLVSSPGSGKTTLLCRTAEALKGRYPLAVIEGDQQTSFDADRIRATGIPAIQVN
TGKGCHLDAHMVESAMAKLNVADDSVLFIENVGNLVCPAAFDLGEAYKVAILSVTEGEDKPLKYPDMFHAASMMILNKTD
LLPHTDFDVERCIGFARRVNPDIVVLQLSARTGEGFDEWLAWINEGRKRMVTERIRRLEAKLAAAKASLEGK
>Mature_312_residues
MCTVCGCGDAKVDGHAHSPHSHDHDHEHHHGHSHDHSHDHPHGHDHHHHDHDSDKDIHYGRGIAGVHVPGMSQKRIVQIE
KDILSHNDDFAGRNRAWLAEHGVFALNLVSSPGSGKTTLLCRTAEALKGRYPLAVIEGDQQTSFDADRIRATGIPAIQVN
TGKGCHLDAHMVESAMAKLNVADDSVLFIENVGNLVCPAAFDLGEAYKVAILSVTEGEDKPLKYPDMFHAASMMILNKTD
LLPHTDFDVERCIGFARRVNPDIVVLQLSARTGEGFDEWLAWINEGRKRMVTERIRRLEAKLAAAKASLEGK

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=289, Percent_Identity=55.7093425605536, Blast_Score=327, Evalue=6e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 34393; Mature: 34393

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCTVCGCGDAKVDGHAHSPHSHDHDHEHHHGHSHDHSHDHPHGHDHHHHDHDSDKDIHYG
CCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RGIAGVHVPGMSQKRIVQIEKDILSHNDDFAGRNRAWLAEHGVFALNLVSSPGSGKTTLL
CCCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCEEEEEEECCCCCCCEEEE
CRTAEALKGRYPLAVIEGDQQTSFDADRIRATGIPAIQVNTGKGCHLDAHMVESAMAKLN
EEEHHHHCCCCCEEEEECCCCCCCCHHHEEECCCCEEEEECCCCCEEHHHHHHHHHHHEE
VADDSVLFIENVGNLVCPAAFDLGEAYKVAILSVTEGEDKPLKYPDMFHAASMMILNKTD
CCCCCEEEEECCCCEECCCHHCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHEEEEECCC
LLPHTDFDVERCIGFARRVNPDIVVLQLSARTGEGFDEWLAWINEGRKRMVTERIRRLEA
CCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KLAAAKASLEGK
HHHHHHHCCCCC
>Mature Secondary Structure
MCTVCGCGDAKVDGHAHSPHSHDHDHEHHHGHSHDHSHDHPHGHDHHHHDHDSDKDIHYG
CCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RGIAGVHVPGMSQKRIVQIEKDILSHNDDFAGRNRAWLAEHGVFALNLVSSPGSGKTTLL
CCCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCEEEEEEECCCCCCCEEEE
CRTAEALKGRYPLAVIEGDQQTSFDADRIRATGIPAIQVNTGKGCHLDAHMVESAMAKLN
EEEHHHHCCCCCEEEEECCCCCCCCHHHEEECCCCEEEEECCCCCEEHHHHHHHHHHHEE
VADDSVLFIENVGNLVCPAAFDLGEAYKVAILSVTEGEDKPLKYPDMFHAASMMILNKTD
CCCCCEEEEECCCCEECCCHHCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHEEEEECCC
LLPHTDFDVERCIGFARRVNPDIVVLQLSARTGEGFDEWLAWINEGRKRMVTERIRRLEA
CCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KLAAAKASLEGK
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486288 [H]