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The map label for this gene is pphA [C]

Identifier: 83310548

GI number: 83310548

Start: 1580620

End: 1581441

Strand: Reverse

Name: pphA [C]

Synonym: amb1449

Alternate gene names: 83310548

Gene position: 1581441-1580620 (Counterclockwise)

Preceding gene: 83310551

Following gene: 83310542

Centisome position: 31.84

GC content: 67.88

Gene sequence:

>822_bases
ATGTCCATCCTGGAAACCCTGATCCGGCCGTTCCGGCGAAACCGCGGGATCGCCCGGCCGTTCCGCCCCCCCGACGGGAC
GAGGATTTATGCCTTCGGCGATGTCCATGGCCGCGCCGATCTGCTGCAATCACTGATGGATTCCGTCGTCGGCGATCTGG
CCCGAGCCGAACGGTCCTGGGATCGCTGCGAGGTGGTGGGACTTGGCGACTATCTGGATCGTGGCCCCCAGTCGCGCCGG
GTCCTGGATCTGTTGATCGGTGCCGCCCTTCCAGCGGGTTGCCGCCTGACCGCCCTTCGGGGCAACCACGAGGACGCCTT
CCTGCACGCCCTGGCCGACCCCATGGCCATTCCCGACTGGCTGGAATACGGCGGAGCTGCCACCCTGGTCAGCTATGGCG
TCGTCCCCATCGCCGGCGCCCCCAGCCGCGAGCGCTCGGAACGCATGCAGGCCGAACTGGCCGCCGCGCTGCCCCCCGCC
CACAAGGCCTTTCTGGCGGCGATGCCGACATCGTTGCGGCTGGGAGATTATCTCTTCGTCCATGCCGGCGTGCGGCCGGG
GCGCCCCCTGGAGCAGCAGGCCCCCGAGGATCTGCTGTGGATCCGCCACGAATTCCTGGCCAGCCGCCGATTCCACGGCG
CCATGATCGTCCACGGCCACCACATCGTTCCCCAGCCGGAGATCCTGGACAACCGCATGGGCATCGACACCGGCGCCTAT
TGCACCAATGTGCTGTCCTGTCTGGTTCTGGAGGGGGACACGGCCGGGCTGATCCAGGCTACGCCGGCCGGGATCAGAAG
AAGCGCTCTCCCACCCAGATGA

Upstream 100 bases:

>100_bases
TGACGTTCTTTCTGGTGCACGCTACGAACCTGGGGCGATATTAAGGGAAAGCCCCGACCGTTTCTAACTCTAATCGCTTT
GGAAAGTCCTCAATCCCCGT

Downstream 100 bases:

>100_bases
CGTCGCCGGGCATGACGGTGCTTTCCATCTGGCCCTTGATCTCGGTCTTGCCCTGGGCGCCCTCGCGGGTGATCTTGATG
TCTTTCTTGTCGGCGCGGTA

Product: diadenosine tetraphosphatase-like protein

Products: A Protein; Orthophosphate. [C]

Alternate protein names: Serine/Threonine Protein Phosphatase; Bis(5Nucleosyl)-Tetraphosphatase ApaH; Serine/Threonine Protein Phosphatase Family Protein; Ser/Thr Protein Phosphatase Family Protein; Serine/Threonine Specific Protein Phosphatase Protein; Serine/Threonine Protein Phosphatase I; Diadenosine Tetraphosphatase; Diadenosine Tetraphosphatase-Like Protein; Phosphatase; Serinethreonine Protein Phosphatase; Phosphoprotein Phosphatase; Calcineurin-Like Phosphoesterase; Bis(5-Nucleosyl)-Tetraphosphatase; Serine/Threonine Protein Phosphatase Protein; Protein Phosphatase; Serine/Threonine-Protein Phosphatase

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MSILETLIRPFRRNRGIARPFRPPDGTRIYAFGDVHGRADLLQSLMDSVVGDLARAERSWDRCEVVGLGDYLDRGPQSRR
VLDLLIGAALPAGCRLTALRGNHEDAFLHALADPMAIPDWLEYGGAATLVSYGVVPIAGAPSRERSERMQAELAAALPPA
HKAFLAAMPTSLRLGDYLFVHAGVRPGRPLEQQAPEDLLWIRHEFLASRRFHGAMIVHGHHIVPQPEILDNRMGIDTGAY
CTNVLSCLVLEGDTAGLIQATPAGIRRSALPPR

Sequences:

>Translated_273_residues
MSILETLIRPFRRNRGIARPFRPPDGTRIYAFGDVHGRADLLQSLMDSVVGDLARAERSWDRCEVVGLGDYLDRGPQSRR
VLDLLIGAALPAGCRLTALRGNHEDAFLHALADPMAIPDWLEYGGAATLVSYGVVPIAGAPSRERSERMQAELAAALPPA
HKAFLAAMPTSLRLGDYLFVHAGVRPGRPLEQQAPEDLLWIRHEFLASRRFHGAMIVHGHHIVPQPEILDNRMGIDTGAY
CTNVLSCLVLEGDTAGLIQATPAGIRRSALPPR
>Mature_272_residues
SILETLIRPFRRNRGIARPFRPPDGTRIYAFGDVHGRADLLQSLMDSVVGDLARAERSWDRCEVVGLGDYLDRGPQSRRV
LDLLIGAALPAGCRLTALRGNHEDAFLHALADPMAIPDWLEYGGAATLVSYGVVPIAGAPSRERSERMQAELAAALPPAH
KAFLAAMPTSLRLGDYLFVHAGVRPGRPLEQQAPEDLLWIRHEFLASRRFHGAMIVHGHHIVPQPEILDNRMGIDTGAYC
TNVLSCLVLEGDTAGLIQATPAGIRRSALPPR

Specific function: Plays A Key Role In Signaling Protein Misfolding Via The Cpxr/Cpxa Transducing System. It Also Modulates The Phosphorylated Status Of Many Phosphoproteins In E. coli, Some Of Which Acting As Major Chaperones. Has Been Shown, In Vitro, To Act On Ser, Thr A

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.3.16 [C]

Molecular weight: Translated: 29838; Mature: 29707

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS00125 SER_THR_PHOSPHATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILETLIRPFRRNRGIARPFRPPDGTRIYAFGDVHGRADLLQSLMDSVVGDLARAERSW
CHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCC
DRCEVVGLGDYLDRGPQSRRVLDLLIGAALPAGCRLTALRGNHEDAFLHALADPMAIPDW
CCEEEEECCHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCCCHH
LEYGGAATLVSYGVVPIAGAPSRERSERMQAELAAALPPAHKAFLAAMPTSLRLGDYLFV
HHHCCHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEE
HAGVRPGRPLEQQAPEDLLWIRHEFLASRRFHGAMIVHGHHIVPQPEILDNRMGIDTGAY
ECCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHCCCCCCHHHH
CTNVLSCLVLEGDTAGLIQATPAGIRRSALPPR
HHHHHHHHHCCCCCCCEEECCCCHHHCCCCCCC
>Mature Secondary Structure 
SILETLIRPFRRNRGIARPFRPPDGTRIYAFGDVHGRADLLQSLMDSVVGDLARAERSW
HHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCC
DRCEVVGLGDYLDRGPQSRRVLDLLIGAALPAGCRLTALRGNHEDAFLHALADPMAIPDW
CCEEEEECCHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCCCHH
LEYGGAATLVSYGVVPIAGAPSRERSERMQAELAAALPPAHKAFLAAMPTSLRLGDYLFV
HHHCCHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEE
HAGVRPGRPLEQQAPEDLLWIRHEFLASRRFHGAMIVHGHHIVPQPEILDNRMGIDTGAY
ECCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHCCCCCCHHHH
CTNVLSCLVLEGDTAGLIQATPAGIRRSALPPR
HHHHHHHHHCCCCCCCEEECCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: A Phosphoprotein; H2O [C]

Specific reaction: A Phosphoprotein + H2O = A Protein + Orthophosphate. [C]

General reaction: Phosphoric ester hydrolysis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA