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The map label for this gene is rpe [H]

Identifier: 83310478

GI number: 83310478

Start: 1495639

End: 1496331

Strand: Reverse

Name: rpe [H]

Synonym: amb1379

Alternate gene names: 83310478

Gene position: 1496331-1495639 (Counterclockwise)

Preceding gene: 83310479

Following gene: 83310477

Centisome position: 30.12

GC content: 63.92

Gene sequence:

>693_bases
ATGGCCGGGTCACGCCCGGCCATGACGATTTCTAAGACAGGACCCAAGCCCATGACCGTCAAGATCGCCCCCAGCATCCT
GTCCGCCGATTTCGCCCGCCTGGGCGAAGAGGTCAAGGCCATCGACGAGGCCGGCTGCGACTGGGTGCATATCGACGTCA
TGGACGGCCATTTCGTGCCCAACCTGACCTTCGGCCCGGCCATCATCAAGGCCATCCGGCCCTATACCACCAAGGTCTTC
GACGTCCATCTGATGATCGACCCGGCCCAGCCCTATATCGAGGACTATGCCAAGGCCGGGGCCGACATCATCGTGGTCCA
TGCCGAGGCCGACAAGCATCTGGACCGCTCGCTGCAGCTGATCCGCTCGCTGGGCAAGAAGGCCGGCGTGTCGCTCAATC
CCTCCACGCCGGAAAGCGTCATCCAATACGTCATGGACAAGCTGGACCTCGTCCTGGTGATGAGCGTCAATCCCGGCTTC
GGCGGCCAGAGCTTCATCGAAGCCCAACTGGACAAGATCGCCCGCATCAAGGCGATGATCGGCACGCGGCCCATCGACCT
GGAAGTGGACGGCGGCGTCACCGCCGACAACGCCCACCGCGTTGTCGCCGCCGGCGCCAACGTCCTGGTGGCCGGTTCGG
CGGTGTTCAAGACCAAGGACTATGCCGCCAACATCGCGGCGTTGCGACGCTGA

Upstream 100 bases:

>100_bases
GGTGAACTGAGAAGCTTCTATCATTTCGTCACCCCCGGGCCACCGGGTCTGGCCGAAAGGCCAGCCCGGCGGTGAACTTC
ACGCCCCGGGGGTCCCATGG

Downstream 100 bases:

>100_bases
CGCCCCCTTGGCAATTGGCGCAGCCATAGGATACTATAGACATATCCTGAATGGCGGGGTCAGTTCTATGAGCGAGCACA
TTTCCTGGTCAGACGACCTC

Product: Pentose-5-phosphate-3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MAGSRPAMTISKTGPKPMTVKIAPSILSADFARLGEEVKAIDEAGCDWVHIDVMDGHFVPNLTFGPAIIKAIRPYTTKVF
DVHLMIDPAQPYIEDYAKAGADIIVVHAEADKHLDRSLQLIRSLGKKAGVSLNPSTPESVIQYVMDKLDLVLVMSVNPGF
GGQSFIEAQLDKIARIKAMIGTRPIDLEVDGGVTADNAHRVVAAGANVLVAGSAVFKTKDYAANIAALRR

Sequences:

>Translated_230_residues
MAGSRPAMTISKTGPKPMTVKIAPSILSADFARLGEEVKAIDEAGCDWVHIDVMDGHFVPNLTFGPAIIKAIRPYTTKVF
DVHLMIDPAQPYIEDYAKAGADIIVVHAEADKHLDRSLQLIRSLGKKAGVSLNPSTPESVIQYVMDKLDLVLVMSVNPGF
GGQSFIEAQLDKIARIKAMIGTRPIDLEVDGGVTADNAHRVVAAGANVLVAGSAVFKTKDYAANIAALRR
>Mature_229_residues
AGSRPAMTISKTGPKPMTVKIAPSILSADFARLGEEVKAIDEAGCDWVHIDVMDGHFVPNLTFGPAIIKAIRPYTTKVFD
VHLMIDPAQPYIEDYAKAGADIIVVHAEADKHLDRSLQLIRSLGKKAGVSLNPSTPESVIQYVMDKLDLVLVMSVNPGFG
GQSFIEAQLDKIARIKAMIGTRPIDLEVDGGVTADNAHRVVAAGANVLVAGSAVFKTKDYAANIAALRR

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=213, Percent_Identity=38.0281690140845, Blast_Score=165, Evalue=4e-41,
Organism=Homo sapiens, GI219879828, Length=213, Percent_Identity=36.150234741784, Blast_Score=155, Evalue=4e-38,
Organism=Homo sapiens, GI24307923, Length=166, Percent_Identity=30.7228915662651, Blast_Score=92, Evalue=4e-19,
Organism=Escherichia coli, GI1789788, Length=211, Percent_Identity=54.9763033175355, Blast_Score=225, Evalue=1e-60,
Organism=Escherichia coli, GI1790523, Length=210, Percent_Identity=40, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1790754, Length=207, Percent_Identity=32.3671497584541, Blast_Score=108, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17552948, Length=220, Percent_Identity=40, Blast_Score=162, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6322341, Length=212, Percent_Identity=40.5660377358491, Blast_Score=166, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24586301, Length=215, Percent_Identity=38.6046511627907, Blast_Score=154, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 24616; Mature: 24485

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGSRPAMTISKTGPKPMTVKIAPSILSADFARLGEEVKAIDEAGCDWVHIDVMDGHFVP
CCCCCCCEEEECCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
NLTFGPAIIKAIRPYTTKVFDVHLMIDPAQPYIEDYAKAGADIIVVHAEADKHLDRSLQL
CCCCCHHHHHHHCCCCEEEEEEEEEECCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHH
IRSLGKKAGVSLNPSTPESVIQYVMDKLDLVLVMSVNPGFGGQSFIEAQLDKIARIKAMI
HHHHHHHCCCCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
GTRPIDLEVDGGVTADNAHRVVAAGANVLVAGSAVFKTKDYAANIAALRR
CCCCEEEEECCCCCCCCCCEEEEECCCEEEECCEEEECHHHHHHHHHHCC
>Mature Secondary Structure 
AGSRPAMTISKTGPKPMTVKIAPSILSADFARLGEEVKAIDEAGCDWVHIDVMDGHFVP
CCCCCCEEEECCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
NLTFGPAIIKAIRPYTTKVFDVHLMIDPAQPYIEDYAKAGADIIVVHAEADKHLDRSLQL
CCCCCHHHHHHHCCCCEEEEEEEEEECCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHH
IRSLGKKAGVSLNPSTPESVIQYVMDKLDLVLVMSVNPGFGGQSFIEAQLDKIARIKAMI
HHHHHHHCCCCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
GTRPIDLEVDGGVTADNAHRVVAAGANVLVAGSAVFKTKDYAANIAALRR
CCCCEEEEECCCCCCCCCCEEEEECCCEEEECCEEEECHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231; 9298645 [H]