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The map label for this gene is iorA [H]

Identifier: 83310401

GI number: 83310401

Start: 1422794

End: 1423201

Strand: Reverse

Name: iorA [H]

Synonym: amb1303

Alternate gene names: 83310401

Gene position: 1423201-1422794 (Counterclockwise)

Preceding gene: 83310407

Following gene: 83310400

Centisome position: 28.65

GC content: 70.83

Gene sequence:

>408_bases
ATGCCGCTGGTCTACTGGCTGCGCGAGGAACTGGGCCTGACCGGGACCCATCTGGGATGCGGCAAGGGGGAATGCGGCGC
CTGCACGGTGCTGATCGACGGCCAGCCCGCCCGGTCGTGCCGGACCACCCTGGGCGAGGCGGCGGGCAAGGTGGTGACCA
CCATCGAGGGCCTGGGCACCCCCGAGGCTCCCCATCCGGTCCAGGCCGCCTTCGTGGAAGAGCAGGCGGCCCAATGCGGT
TTCTGCACACCGGGAATGGTGGTGGAGGGCGCCGCCCTGCTGGCCCGCACGGCCCAGCCGGATCTGGCGGAGGTCAAGGA
GGCGCTGGACGGCCATCTCTGCCGCTGCGGCAGCCACCAAAGAGTTCTCAAGGCCGTGATGCGCGCCGGCGGGAGGGACA
AGTCATGA

Upstream 100 bases:

>100_bases
GGCCGGAAAACCCGCGACCGCCGCGAAGGCGAAATCCCCCGCCCAACTCTCCCTCACCGTCAACGGCACGGAACGCCGCG
CCGCGCTGGCCGACGGCGAC

Downstream 100 bases:

>100_bases
GCCTCGATCTGTCCCGGCGCGCCCTGCTGGGCTCCATGGCGGCCCTGACCGTGGCCTTCGCCCTGCCCCGCCCCTCTGGA
GCCGCCGCCGCCTTGGCCAA

Product: aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 135; Mature: 134

Protein sequence:

>135_residues
MPLVYWLREELGLTGTHLGCGKGECGACTVLIDGQPARSCRTTLGEAAGKVVTTIEGLGTPEAPHPVQAAFVEEQAAQCG
FCTPGMVVEGAALLARTAQPDLAEVKEALDGHLCRCGSHQRVLKAVMRAGGRDKS

Sequences:

>Translated_135_residues
MPLVYWLREELGLTGTHLGCGKGECGACTVLIDGQPARSCRTTLGEAAGKVVTTIEGLGTPEAPHPVQAAFVEEQAAQCG
FCTPGMVVEGAALLARTAQPDLAEVKEALDGHLCRCGSHQRVLKAVMRAGGRDKS
>Mature_134_residues
PLVYWLREELGLTGTHLGCGKGECGACTVLIDGQPARSCRTTLGEAAGKVVTTIEGLGTPEAPHPVQAAFVEEQAAQCGF
CTPGMVVEGAALLARTAQPDLAEVKEALDGHLCRCGSHQRVLKAVMRAGGRDKS

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=133, Percent_Identity=38.3458646616541, Blast_Score=77, Evalue=4e-15,
Organism=Homo sapiens, GI71773480, Length=98, Percent_Identity=38.7755102040816, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI1786480, Length=148, Percent_Identity=39.1891891891892, Blast_Score=110, Evalue=5e-26,
Organism=Escherichia coli, GI1789232, Length=128, Percent_Identity=41.40625, Blast_Score=93, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17540638, Length=135, Percent_Identity=40.7407407407407, Blast_Score=108, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17539860, Length=136, Percent_Identity=35.2941176470588, Blast_Score=102, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI32566215, Length=136, Percent_Identity=36.0294117647059, Blast_Score=101, Evalue=1e-22,
Organism=Drosophila melanogaster, GI17737937, Length=133, Percent_Identity=39.8496240601504, Blast_Score=96, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24647197, Length=133, Percent_Identity=33.8345864661654, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24647199, Length=127, Percent_Identity=33.8582677165354, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24647195, Length=142, Percent_Identity=33.0985915492958, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24647201, Length=127, Percent_Identity=33.0708661417323, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24647193, Length=147, Percent_Identity=31.9727891156463, Blast_Score=73, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 14057; Mature: 13926

Theoretical pI: Translated: 6.49; Mature: 6.49

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
6.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLVYWLREELGLTGTHLGCGKGECGACTVLIDGQPARSCRTTLGEAAGKVVTTIEGLGT
CCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCC
PEAPHPVQAAFVEEQAAQCGFCTPGMVVEGAALLARTAQPDLAEVKEALDGHLCRCGSHQ
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCHHHCCCCHH
RVLKAVMRAGGRDKS
HHHHHHHHCCCCCCC
>Mature Secondary Structure 
PLVYWLREELGLTGTHLGCGKGECGACTVLIDGQPARSCRTTLGEAAGKVVTTIEGLGT
CHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCC
PEAPHPVQAAFVEEQAAQCGFCTPGMVVEGAALLARTAQPDLAEVKEALDGHLCRCGSHQ
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCHHHCCCCHH
RVLKAVMRAGGRDKS
HHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]