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The map label for this gene is iorB [H]

Identifier: 83310400

GI number: 83310400

Start: 1420614

End: 1422797

Strand: Reverse

Name: iorB [H]

Synonym: amb1301

Alternate gene names: 83310400

Gene position: 1422797-1420614 (Counterclockwise)

Preceding gene: 83310401

Following gene: 83310399

Centisome position: 28.64

GC content: 71.25

Gene sequence:

>2184_bases
ATGAGCCTCGATCTGTCCCGGCGCGCCCTGCTGGGCTCCATGGCGGCCCTGACCGTGGCCTTCGCCCTGCCCCGCCCCTC
TGGAGCCGCCGCCGCCTTGGCCAAGACCAACGATCCCGCCGAGGTGGACGGGTTCTTGGCCATCGGCGCCGACGGCAAGG
TCACCGTCTATTGCGGCAAGGTCGATCTCGGCCAGGGCCTGCGCGTCGCCATCCGCCAGATGGCCGCCGAGGAACTGGGT
ATCGGCATTGACTCCATCGCCCTGGTCGAGGGCGACACGGCGCTGACCCCCGACCAGGGACCCACCGCCGGCTCCACCGG
CGTGGCCAAGGGCGGCGTGCAGATCCGCCAGGCGGCCGCCACGGCGCGTCAGGCCCTGATCCGCCTCGCCGCCGCAAGGC
TGGACCTACCCGCCGAGGAACTGGATCTCCGCGACGGCGTGGTGGGCCCCCGGGAATCTGGCCGCTCCATCGCCATGGGC
GATCTGGTGGGCGAGGGCGGCTTCGCCCTGAAGTTGGACCCCAAGGCGCCGCTGCGCAATCCCGCCGACTATCGCGTGGT
GGGCAAGCCCCTGCCCCGCCCCGACCTGCCGGCCAAGGTCTGCGGCACCCATGTTTATGTCCACGACTTCAAGCTGCCCG
GCATGCTGCATGGCCGCGTCATCCGCCCGCCCTCGGTGGGCGCCAGCCTGCTCCGGGTGGACGAGGCCTCCATCAAGGCC
ATCCGCGGCGCCCGCGTGGTGCGCCTCAAGGACTTCCTGGCCGTGGTGGCCCCCCGCGAATGGGACGCCGTCCGCGCCGC
CGGGATGCTGAAGGCGCAATGGTCGGATTCCGCCCCGCTGATGGGTCATCAGGCGGTGCGCGACTGGCTGAAGACCCCGC
CCTTCGCCGCCGAGGAGGTGTTGAAGGCCAAGGGCGACGCCGCCGCCGCCCTGGCCGACGCGCCGCCCGCCGCCGAGTAT
TACTGGCCGGTGCAGTCCCACGGCTCGCTGGGGCCGAGCTGCGCGGTGGCCCAGGTCAAAGACGGCGCCGCCACCATCTG
GACCGCGTCGCAGGCCACCCACAAGTTCCGCCCCGCCTTGGCCGCCCTGCTGGGCCTGGGCGTGGACAAGGTGCGCATGG
TCTATCTGGACGGCTCGGGCTGCTACGGCATGAACGGCCATGACGACGCCAGCGCCGACGCCGCCCTGCTGGCCAAGGCC
ACGGGCAAGCCGGTCCGGGTCGCCTGGAGCCGGGATGACGAGCTGGCCTGGGACCCCAAGGGTCCGCCGCAATTGCTGGC
CATTCGCGGCGCCATGGCGCCCTCCGGCCTGCTGGCCGGCTGGAGCACCGAGATGTGGCTCCCCAAGGCCACCGCCGGAC
TGGTCAACGTGCCGTTGCTGGCCCCCGAGGCGGCGGGCATCGCCCAGCCCCAGGGCCTGATCACCGGCCTGATCTCCCAG
AACGGCGATCCGCCCTATGCCGTCGCCGATCTGGAGGTCAAGGTCCACTGGCAGGCCGAAGCCCCCTTGCGCCCCAGCAA
CATCCGCGCGCCGGGCAAGATCGCCAACACCTTCGCGGTGGAAGGCTATTTCGATGAGCTGTGCGCTGGCGTGGGGCTGG
ACCCCCTGGTCACCCGCCTGATCGGCCTCCGGGATCTGCGGGGCGTCGCCGTGCTGACCAAGGCCGCGTCCATGATGGCC
TGGGCGCCGCGCCCCTCGCCCAACCCCGCCGGCGACGGCACCGGGCGCGGCATCGCCTATGTTCACTACAAGCACTCGGA
AACCTATGTGGGCATGGCCATGGAGGTCATGGTCGACCGCGACACCGGGCGCATCGCCATCAAGAAGGTGACCTGCGCCC
ATGATTGCGGGCTGGTGATCAATCCCGACGCGCTGAAGATGCAGATCGAGGGCTGCATCCTCCAGACCCTGTCGCGCACC
CTGCTGGAAGAGGTGGCCTTCGACGCCTCGCGCGTCACCTCCACCGACCAGTCCACCTACCCCATCCTCGGTTTCGGCGC
GGTCCCCGACATCGCCATCGAGCTGCTGGACCGGCCCGACCAACCGCCCATGGGTGGCGGCGAAGCGGCCTGCGCCCCGG
TGCCCGCCGCCCTGGCCAACGCGGTGTTCGACGCGGTGGGGGCAAGGCTGCGCACCGTGCCGTTCACGCCCGAGCGGGTG
AAGGGAGTTTTACAGGCCTTGTAG

Upstream 100 bases:

>100_bases
TGGCGGAGGTCAAGGAGGCGCTGGACGGCCATCTCTGCCGCTGCGGCAGCCACCAAAGAGTTCTCAAGGCCGTGATGCGC
GCCGGCGGGAGGGACAAGTC

Downstream 100 bases:

>100_bases
CCCACGATCCGACTAGCTACATTATTGCAATGGCAATTAGACGGAAACTACACAAACCATGACGGACATTCGCGACGGCT
TCCTCGATTCCATCGGCAAC

Product: aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 727; Mature: 726

Protein sequence:

>727_residues
MSLDLSRRALLGSMAALTVAFALPRPSGAAAALAKTNDPAEVDGFLAIGADGKVTVYCGKVDLGQGLRVAIRQMAAEELG
IGIDSIALVEGDTALTPDQGPTAGSTGVAKGGVQIRQAAATARQALIRLAAARLDLPAEELDLRDGVVGPRESGRSIAMG
DLVGEGGFALKLDPKAPLRNPADYRVVGKPLPRPDLPAKVCGTHVYVHDFKLPGMLHGRVIRPPSVGASLLRVDEASIKA
IRGARVVRLKDFLAVVAPREWDAVRAAGMLKAQWSDSAPLMGHQAVRDWLKTPPFAAEEVLKAKGDAAAALADAPPAAEY
YWPVQSHGSLGPSCAVAQVKDGAATIWTASQATHKFRPALAALLGLGVDKVRMVYLDGSGCYGMNGHDDASADAALLAKA
TGKPVRVAWSRDDELAWDPKGPPQLLAIRGAMAPSGLLAGWSTEMWLPKATAGLVNVPLLAPEAAGIAQPQGLITGLISQ
NGDPPYAVADLEVKVHWQAEAPLRPSNIRAPGKIANTFAVEGYFDELCAGVGLDPLVTRLIGLRDLRGVAVLTKAASMMA
WAPRPSPNPAGDGTGRGIAYVHYKHSETYVGMAMEVMVDRDTGRIAIKKVTCAHDCGLVINPDALKMQIEGCILQTLSRT
LLEEVAFDASRVTSTDQSTYPILGFGAVPDIAIELLDRPDQPPMGGGEAACAPVPAALANAVFDAVGARLRTVPFTPERV
KGVLQAL

Sequences:

>Translated_727_residues
MSLDLSRRALLGSMAALTVAFALPRPSGAAAALAKTNDPAEVDGFLAIGADGKVTVYCGKVDLGQGLRVAIRQMAAEELG
IGIDSIALVEGDTALTPDQGPTAGSTGVAKGGVQIRQAAATARQALIRLAAARLDLPAEELDLRDGVVGPRESGRSIAMG
DLVGEGGFALKLDPKAPLRNPADYRVVGKPLPRPDLPAKVCGTHVYVHDFKLPGMLHGRVIRPPSVGASLLRVDEASIKA
IRGARVVRLKDFLAVVAPREWDAVRAAGMLKAQWSDSAPLMGHQAVRDWLKTPPFAAEEVLKAKGDAAAALADAPPAAEY
YWPVQSHGSLGPSCAVAQVKDGAATIWTASQATHKFRPALAALLGLGVDKVRMVYLDGSGCYGMNGHDDASADAALLAKA
TGKPVRVAWSRDDELAWDPKGPPQLLAIRGAMAPSGLLAGWSTEMWLPKATAGLVNVPLLAPEAAGIAQPQGLITGLISQ
NGDPPYAVADLEVKVHWQAEAPLRPSNIRAPGKIANTFAVEGYFDELCAGVGLDPLVTRLIGLRDLRGVAVLTKAASMMA
WAPRPSPNPAGDGTGRGIAYVHYKHSETYVGMAMEVMVDRDTGRIAIKKVTCAHDCGLVINPDALKMQIEGCILQTLSRT
LLEEVAFDASRVTSTDQSTYPILGFGAVPDIAIELLDRPDQPPMGGGEAACAPVPAALANAVFDAVGARLRTVPFTPERV
KGVLQAL
>Mature_726_residues
SLDLSRRALLGSMAALTVAFALPRPSGAAAALAKTNDPAEVDGFLAIGADGKVTVYCGKVDLGQGLRVAIRQMAAEELGI
GIDSIALVEGDTALTPDQGPTAGSTGVAKGGVQIRQAAATARQALIRLAAARLDLPAEELDLRDGVVGPRESGRSIAMGD
LVGEGGFALKLDPKAPLRNPADYRVVGKPLPRPDLPAKVCGTHVYVHDFKLPGMLHGRVIRPPSVGASLLRVDEASIKAI
RGARVVRLKDFLAVVAPREWDAVRAAGMLKAQWSDSAPLMGHQAVRDWLKTPPFAAEEVLKAKGDAAAALADAPPAAEYY
WPVQSHGSLGPSCAVAQVKDGAATIWTASQATHKFRPALAALLGLGVDKVRMVYLDGSGCYGMNGHDDASADAALLAKAT
GKPVRVAWSRDDELAWDPKGPPQLLAIRGAMAPSGLLAGWSTEMWLPKATAGLVNVPLLAPEAAGIAQPQGLITGLISQN
GDPPYAVADLEVKVHWQAEAPLRPSNIRAPGKIANTFAVEGYFDELCAGVGLDPLVTRLIGLRDLRGVAVLTKAASMMAW
APRPSPNPAGDGTGRGIAYVHYKHSETYVGMAMEVMVDRDTGRIAIKKVTCAHDCGLVINPDALKMQIEGCILQTLSRTL
LEEVAFDASRVTSTDQSTYPILGFGAVPDIAIELLDRPDQPPMGGGEAACAPVPAALANAVFDAVGARLRTVPFTPERVK
GVLQAL

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786478, Length=145, Percent_Identity=29.6551724137931, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012368
- InterPro:   IPR006311 [H]

Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 76017; Mature: 75886

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLDLSRRALLGSMAALTVAFALPRPSGAAAALAKTNDPAEVDGFLAIGADGKVTVYCGK
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEECCCCEEEEEECC
VDLGQGLRVAIRQMAAEELGIGIDSIALVEGDTALTPDQGPTAGSTGVAKGGVQIRQAAA
EECCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
TARQALIRLAAARLDLPAEELDLRDGVVGPRESGRSIAMGDLVGEGGFALKLDPKAPLRN
HHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCEEEEEEEECCCCEEEEECCCCCCCC
PADYRVVGKPLPRPDLPAKVCGTHVYVHDFKLPGMLHGRVIRPPSVGASLLRVDEASIKA
CCCCEEECCCCCCCCCCHHHHCCEEEEEEECCCCCCCCCEECCCCCCCHHEEECHHHHHH
IRGARVVRLKDFLAVVAPREWDAVRAAGMLKAQWSDSAPLMGHQAVRDWLKTPPFAAEEV
HCCCEEEEEHHHHHHHCCCCHHHHHHCCEEEECCCCCCCCCCHHHHHHHHCCCCHHHHHH
LKAKGDAAAALADAPPAAEYYWPVQSHGSLGPSCAVAQVKDGAATIWTASQATHKFRPAL
HHCCCCCCEEECCCCCCCCEECCCCCCCCCCCCEEEEEECCCCEEEEECCHHHHHHHHHH
AALLGLGVDKVRMVYLDGSGCYGMNGHDDASADAALLAKATGKPVRVAWSRDDELAWDPK
HHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCC
GPPQLLAIRGAMAPSGLLAGWSTEMWLPKATAGLVNVPLLAPEAAGIAQPQGLITGLISQ
CCCCEEEEECCCCCCCEEECCCCCCCCCCCCCCEEECCEECCCCCCCCCCHHHHHHHHHC
NGDPPYAVADLEVKVHWQAEAPLRPSNIRAPGKIANTFAVEGYFDELCAGVGLDPLVTRL
CCCCCEEEEEEEEEEEEEECCCCCCCCCCCCCCCCCEEEECCHHHHHHHCCCCHHHHHHH
IGLRDLRGVAVLTKAASMMAWAPRPSPNPAGDGTGRGIAYVHYKHSETYVGMAMEVMVDR
HHHHHHCHHHHHHHHHHHHEECCCCCCCCCCCCCCCCEEEEEEECCCEEEEEEEEEEEEC
DTGRIAIKKVTCAHDCGLVINPDALKMQIEGCILQTLSRTLLEEVAFDASRVTSTDQSTY
CCCEEEEEEEEECCCCCEEECCHHHEEEHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCC
PILGFGAVPDIAIELLDRPDQPPMGGGEAACAPVPAALANAVFDAVGARLRTVPFTPERV
CEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCHHHH
KGVLQAL
HHHHHCC
>Mature Secondary Structure 
SLDLSRRALLGSMAALTVAFALPRPSGAAAALAKTNDPAEVDGFLAIGADGKVTVYCGK
CCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEECCCCEEEEEECC
VDLGQGLRVAIRQMAAEELGIGIDSIALVEGDTALTPDQGPTAGSTGVAKGGVQIRQAAA
EECCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
TARQALIRLAAARLDLPAEELDLRDGVVGPRESGRSIAMGDLVGEGGFALKLDPKAPLRN
HHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCEEEEEEEECCCCEEEEECCCCCCCC
PADYRVVGKPLPRPDLPAKVCGTHVYVHDFKLPGMLHGRVIRPPSVGASLLRVDEASIKA
CCCCEEECCCCCCCCCCHHHHCCEEEEEEECCCCCCCCCEECCCCCCCHHEEECHHHHHH
IRGARVVRLKDFLAVVAPREWDAVRAAGMLKAQWSDSAPLMGHQAVRDWLKTPPFAAEEV
HCCCEEEEEHHHHHHHCCCCHHHHHHCCEEEECCCCCCCCCCHHHHHHHHCCCCHHHHHH
LKAKGDAAAALADAPPAAEYYWPVQSHGSLGPSCAVAQVKDGAATIWTASQATHKFRPAL
HHCCCCCCEEECCCCCCCCEECCCCCCCCCCCCEEEEEECCCCEEEEECCHHHHHHHHHH
AALLGLGVDKVRMVYLDGSGCYGMNGHDDASADAALLAKATGKPVRVAWSRDDELAWDPK
HHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCC
GPPQLLAIRGAMAPSGLLAGWSTEMWLPKATAGLVNVPLLAPEAAGIAQPQGLITGLISQ
CCCCEEEEECCCCCCCEEECCCCCCCCCCCCCCEEECCEECCCCCCCCCCHHHHHHHHHC
NGDPPYAVADLEVKVHWQAEAPLRPSNIRAPGKIANTFAVEGYFDELCAGVGLDPLVTRL
CCCCCEEEEEEEEEEEEEECCCCCCCCCCCCCCCCCEEEECCHHHHHHHCCCCHHHHHHH
IGLRDLRGVAVLTKAASMMAWAPRPSPNPAGDGTGRGIAYVHYKHSETYVGMAMEVMVDR
HHHHHHCHHHHHHHHHHHHEECCCCCCCCCCCCCCCCEEEEEEECCCEEEEEEEEEEEEC
DTGRIAIKKVTCAHDCGLVINPDALKMQIEGCILQTLSRTLLEEVAFDASRVTSTDQSTY
CCCEEEEEEEEECCCCCEEECCHHHEEEHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCC
PILGFGAVPDIAIELLDRPDQPPMGGGEAACAPVPAALANAVFDAVGARLRTVPFTPERV
CEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCHHHH
KGVLQAL
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]