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The map label for this gene is cya1 [H]

Identifier: 83310325

GI number: 83310325

Start: 1301287

End: 1303428

Strand: Reverse

Name: cya1 [H]

Synonym: amb1226

Alternate gene names: 83310325

Gene position: 1303428-1301287 (Counterclockwise)

Preceding gene: 83310326

Following gene: 83310324

Centisome position: 26.24

GC content: 67.55

Gene sequence:

>2142_bases
ATGCCACCGAAAGGATTCCGCATCCGCTTGCGGGTCGGCATTACCGTCATGTTCCTCAGCGTCATGCTGCCGCTGACGGC
GTTGATGACCGCTGTTCTCTATCGCCAGAACTCCCAGTTGGCCATCCAGCTGGCCGAACACGCCATGGACAGCGCCACCA
CCGACGTGGTGTCCGGGGTCGGTTCGCTGCTGGGCCCCATGGGCCGGGTGGCCGACCTGTCGGTGGCTTTTGGCAAGGCG
GAAGGCGATTCCATTCGCCGGGTCGAAGGACTGCGCCCGCTGGTCGAGGCGCTGGAGAAGTTCCCCGATATCTACGCCCT
GTTCTTCGGCTTCGCCCGCGACGGCGCCTTCTACGAGGTGATCCGGGTTCCCCCTCCCGGTTCGGGCATCACGCTGAAGG
GCCGCAATCCCCCGCCGAACGCCAATTACGCCCTGCGCTTCATCGACACGGTGGATGACGAGCGGGTCGACAACTGGATC
TACATCACCCATTGGGGCGAGGTGGTCGGGCTGGAGCGCGCGGCCAAGGCCACTTACGACCCGCGCAACCGGCCCTGGTA
TCTGGCGGCGCTCAAAACCAACGAAATCGCCACCTCCAGCCTGCATGTCTTCAGCAGCATCGGGCGTCCGGGCCTGACCC
TGTCGCGCCAGCTGGCCACCGACGACGGGCAGGTCATCGCGGTTTTCGGCGCCGACCTGTCCATCGACACCCTGTCCAAA
GTGCTGGCCGACCACCGGATCGGCGACAACGGCCAGGTCTTCATCCTGGACGAGGAAGGGCGGCTGCTGGGATATCCCGA
CCCCCAGCGCGTCCTGGTCCAGCAGGGCGGCCATGTGGAGATCGCCAAGGCAGAGGAGTTCTCCGACCCCGTCCTGGCCG
GCGCGGTCAGGAAGCGGGCCGCCGGAGCCGGTGACCGCTTCCGCGCCACCCTGGGTCCCGACGGCGACGAATATCTGGTG
GCGTTCTCGCGCTTTCCCGAAAGCTTCGGCAAGAACTGGACCATCGGCGTCATCGCCGCCGAGGCCGACTTCGTCGGTCC
CCTGCGCAAGGCCAGCGGCATGATCCTGCTGATCGGCGCAGGCTTCCTGCTGCTGTCGAGCGTCGCGGTGGTCTGGGCGT
CGAGCCTGCTGACCACCCCCATCCGGGCCCTGACCGACGAGGCCGACCGCATCCGCAGGCTGGAACTGGATCACGACATC
ACGGTAAACAGCCCGGTGGTGGAGGTTCAGTCCCTGGCGGCGGGGCTTGCCACCATGAAGGCCGCGCTGAGGAGCTTTGG
CGCCTATGTGCCCAAGGGTATCCTCAGGCGCATCGTCGAGTCGGGCACCAGCACCGAGATCGGCGGCGAGCGGCGCGAGC
TGACCATCCTGTTCACCGACATCAAGGGCTTCACCCGCACCAGCGAGGATATGGCGCCCGAGGACGTCCTGCATCACCTG
TCCGTCTATCTGGAAGGCATGTCCGGCGCCATCGCCGCCCATAACGGCACCGTGGACAAGTTCATCGGCGACGCGGTCAT
GGCGCTGTGGAACGCCCCCCAGCACGACCCCGACCACGTGCTGCACGCCTGCCGCGCCATGCTGGCCTGCCGGGCCGCCA
CGGCGGGGCTCAATGCCGAGCTGATCGCCAACAATTACCCTCCCATGCCCACCCGCTACGGCCTCCACACCGGCATGGCG
GTGGCGGGAAACGTGGGGTGCCGCGACCGCATGCAATACACCGCCCTGGGCGCGGCGGTGAACCTGGCCTCGCGGGTGGA
ATCCCTGAACAAGCATTTCGGCACCGAGATGCTGGTCACCGGCGAGGTTGAGGACGTGGTCCGCGACCAGTTCGTCCTGC
GCCCCCTGGGGCCGGTGGTCGCTTCGGGAACCAGCATCCCCATCCTGCTGTTCGAACTGGTGGGCGCGCTGGAAGGCCAG
CCCCACGCGGCCAGCCCCGAGGATCTGGCGCGGGTCGCCCGCTGGCGCGAGGCCTTCTCCGCCTATGTGGACGGCGATTG
GGCCAGGGCGGCGGAGCTGTTCCGCGCCTATGGCGCGGTCTACTCCAACGACGAGGCCGGGCGGTTGCTGCAGGCACGCG
CCGCGGCCAACGCCGCCGACCCCGGCCATGCCGAATTCGCCATTCAGTTTGCCGAGAAATAG

Upstream 100 bases:

>100_bases
GGCGAGGCCTTCTGATACTTCCCCTGAAACGGGCGTTTGCGCCGCAGCAAATAGTACTATAACTTAGGCATCGCAATCGC
TGCGAAGAGGGGGGAGCGAG

Downstream 100 bases:

>100_bases
GCCATGCCCCATCGCCTCCTCGCCGCCTTTCTCCTGCTGGTGCTGCTCGGCGGCCCGCAAGCCCTCGCCCAGACCAGCGT
TCATCTGGCCCATTCCCAGC

Product: adenylate cyclase 1

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 1; Adenylyl cyclase 1 [H]

Number of amino acids: Translated: 713; Mature: 712

Protein sequence:

>713_residues
MPPKGFRIRLRVGITVMFLSVMLPLTALMTAVLYRQNSQLAIQLAEHAMDSATTDVVSGVGSLLGPMGRVADLSVAFGKA
EGDSIRRVEGLRPLVEALEKFPDIYALFFGFARDGAFYEVIRVPPPGSGITLKGRNPPPNANYALRFIDTVDDERVDNWI
YITHWGEVVGLERAAKATYDPRNRPWYLAALKTNEIATSSLHVFSSIGRPGLTLSRQLATDDGQVIAVFGADLSIDTLSK
VLADHRIGDNGQVFILDEEGRLLGYPDPQRVLVQQGGHVEIAKAEEFSDPVLAGAVRKRAAGAGDRFRATLGPDGDEYLV
AFSRFPESFGKNWTIGVIAAEADFVGPLRKASGMILLIGAGFLLLSSVAVVWASSLLTTPIRALTDEADRIRRLELDHDI
TVNSPVVEVQSLAAGLATMKAALRSFGAYVPKGILRRIVESGTSTEIGGERRELTILFTDIKGFTRTSEDMAPEDVLHHL
SVYLEGMSGAIAAHNGTVDKFIGDAVMALWNAPQHDPDHVLHACRAMLACRAATAGLNAELIANNYPPMPTRYGLHTGMA
VAGNVGCRDRMQYTALGAAVNLASRVESLNKHFGTEMLVTGEVEDVVRDQFVLRPLGPVVASGTSIPILLFELVGALEGQ
PHAASPEDLARVARWREAFSAYVDGDWARAAELFRAYGAVYSNDEAGRLLQARAAANAADPGHAEFAIQFAEK

Sequences:

>Translated_713_residues
MPPKGFRIRLRVGITVMFLSVMLPLTALMTAVLYRQNSQLAIQLAEHAMDSATTDVVSGVGSLLGPMGRVADLSVAFGKA
EGDSIRRVEGLRPLVEALEKFPDIYALFFGFARDGAFYEVIRVPPPGSGITLKGRNPPPNANYALRFIDTVDDERVDNWI
YITHWGEVVGLERAAKATYDPRNRPWYLAALKTNEIATSSLHVFSSIGRPGLTLSRQLATDDGQVIAVFGADLSIDTLSK
VLADHRIGDNGQVFILDEEGRLLGYPDPQRVLVQQGGHVEIAKAEEFSDPVLAGAVRKRAAGAGDRFRATLGPDGDEYLV
AFSRFPESFGKNWTIGVIAAEADFVGPLRKASGMILLIGAGFLLLSSVAVVWASSLLTTPIRALTDEADRIRRLELDHDI
TVNSPVVEVQSLAAGLATMKAALRSFGAYVPKGILRRIVESGTSTEIGGERRELTILFTDIKGFTRTSEDMAPEDVLHHL
SVYLEGMSGAIAAHNGTVDKFIGDAVMALWNAPQHDPDHVLHACRAMLACRAATAGLNAELIANNYPPMPTRYGLHTGMA
VAGNVGCRDRMQYTALGAAVNLASRVESLNKHFGTEMLVTGEVEDVVRDQFVLRPLGPVVASGTSIPILLFELVGALEGQ
PHAASPEDLARVARWREAFSAYVDGDWARAAELFRAYGAVYSNDEAGRLLQARAAANAADPGHAEFAIQFAEK
>Mature_712_residues
PPKGFRIRLRVGITVMFLSVMLPLTALMTAVLYRQNSQLAIQLAEHAMDSATTDVVSGVGSLLGPMGRVADLSVAFGKAE
GDSIRRVEGLRPLVEALEKFPDIYALFFGFARDGAFYEVIRVPPPGSGITLKGRNPPPNANYALRFIDTVDDERVDNWIY
ITHWGEVVGLERAAKATYDPRNRPWYLAALKTNEIATSSLHVFSSIGRPGLTLSRQLATDDGQVIAVFGADLSIDTLSKV
LADHRIGDNGQVFILDEEGRLLGYPDPQRVLVQQGGHVEIAKAEEFSDPVLAGAVRKRAAGAGDRFRATLGPDGDEYLVA
FSRFPESFGKNWTIGVIAAEADFVGPLRKASGMILLIGAGFLLLSSVAVVWASSLLTTPIRALTDEADRIRRLELDHDIT
VNSPVVEVQSLAAGLATMKAALRSFGAYVPKGILRRIVESGTSTEIGGERRELTILFTDIKGFTRTSEDMAPEDVLHHLS
VYLEGMSGAIAAHNGTVDKFIGDAVMALWNAPQHDPDHVLHACRAMLACRAATAGLNAELIANNYPPMPTRYGLHTGMAV
AGNVGCRDRMQYTALGAAVNLASRVESLNKHFGTEMLVTGEVEDVVRDQFVLRPLGPVVASGTSIPILLFELVGALEGQP
HAASPEDLARVARWREAFSAYVDGDWARAAELFRAYGAVYSNDEAGRLLQARAAANAADPGHAEFAIQFAEK

Specific function: Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00672 HAMP [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 76965; Mature: 76834

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS50885 HAMP ; PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPKGFRIRLRVGITVMFLSVMLPLTALMTAVLYRQNSQLAIQLAEHAMDSATTDVVSGV
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
GSLLGPMGRVADLSVAFGKAEGDSIRRVEGLRPLVEALEKFPDIYALFFGFARDGAFYEV
HHHHCCCCCHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEE
IRVPPPGSGITLKGRNPPPNANYALRFIDTVDDERVDNWIYITHWGEVVGLERAAKATYD
EECCCCCCCEEEECCCCCCCCCEEEEEEECCCCCCCCCEEEEEECCHHHHHHHHHHCCCC
PRNRPWYLAALKTNEIATSSLHVFSSIGRPGLTLSRQLATDDGQVIAVFGADLSIDTLSK
CCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCEEEHHCCCCCCCEEEEEECCCCHHHHHH
VLADHRIGDNGQVFILDEEGRLLGYPDPQRVLVQQGGHVEIAKAEEFSDPVLAGAVRKRA
HHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHH
AGAGDRFRATLGPDGDEYLVAFSRFPESFGKNWTIGVIAAEADFVGPLRKASGMILLIGA
CCCCCCEEEECCCCCCCEEHHHHHCHHHHCCCEEEEEEEECCHHHCCHHHHCCEEEEECH
GFLLLSSVAVVWASSLLTTPIRALTDEADRIRRLELDHDITVNSPVVEVQSLAAGLATMK
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHEEECCCCEECCCCHHHHHHHHHHHHHHH
AALRSFGAYVPKGILRRIVESGTSTEIGGERRELTILFTDIKGFTRTSEDMAPEDVLHHL
HHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHH
SVYLEGMSGAIAAHNGTVDKFIGDAVMALWNAPQHDPDHVLHACRAMLACRAATAGLNAE
HHHHHCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEE
LIANNYPPMPTRYGLHTGMAVAGNVGCRDRMQYTALGAAVNLASRVESLNKHFGTEMLVT
EEECCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
GEVEDVVRDQFVLRPLGPVVASGTSIPILLFELVGALEGQPHAASPEDLARVARWREAFS
CCHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
AYVDGDWARAAELFRAYGAVYSNDEAGRLLQARAAANAADPGHAEFAIQFAEK
HHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCC
>Mature Secondary Structure 
PPKGFRIRLRVGITVMFLSVMLPLTALMTAVLYRQNSQLAIQLAEHAMDSATTDVVSGV
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
GSLLGPMGRVADLSVAFGKAEGDSIRRVEGLRPLVEALEKFPDIYALFFGFARDGAFYEV
HHHHCCCCCHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEE
IRVPPPGSGITLKGRNPPPNANYALRFIDTVDDERVDNWIYITHWGEVVGLERAAKATYD
EECCCCCCCEEEECCCCCCCCCEEEEEEECCCCCCCCCEEEEEECCHHHHHHHHHHCCCC
PRNRPWYLAALKTNEIATSSLHVFSSIGRPGLTLSRQLATDDGQVIAVFGADLSIDTLSK
CCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCEEEHHCCCCCCCEEEEEECCCCHHHHHH
VLADHRIGDNGQVFILDEEGRLLGYPDPQRVLVQQGGHVEIAKAEEFSDPVLAGAVRKRA
HHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHH
AGAGDRFRATLGPDGDEYLVAFSRFPESFGKNWTIGVIAAEADFVGPLRKASGMILLIGA
CCCCCCEEEECCCCCCCEEHHHHHCHHHHCCCEEEEEEEECCHHHCCHHHHCCEEEEECH
GFLLLSSVAVVWASSLLTTPIRALTDEADRIRRLELDHDITVNSPVVEVQSLAAGLATMK
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHEEECCCCEECCCCHHHHHHHHHHHHHHH
AALRSFGAYVPKGILRRIVESGTSTEIGGERRELTILFTDIKGFTRTSEDMAPEDVLHHL
HHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHH
SVYLEGMSGAIAAHNGTVDKFIGDAVMALWNAPQHDPDHVLHACRAMLACRAATAGLNAE
HHHHHCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEE
LIANNYPPMPTRYGLHTGMAVAGNVGCRDRMQYTALGAAVNLASRVESLNKHFGTEMLVT
EEECCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
GEVEDVVRDQFVLRPLGPVVASGTSIPILLFELVGALEGQPHAASPEDLARVARWREAFS
CCHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
AYVDGDWARAAELFRAYGAVYSNDEAGRLLQARAAANAADPGHAEFAIQFAEK
HHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11481430; 1970565 [H]