Click here to switch to the map view.

The map label for this gene is ucpA [C]

Identifier: 83309843

GI number: 83309843

Start: 805961

End: 806722

Strand: Reverse

Name: ucpA [C]

Synonym: amb0744

Alternate gene names: 83309843

Gene position: 806722-805961 (Counterclockwise)

Preceding gene: 83309844

Following gene: 83309841

Centisome position: 16.24

GC content: 71.13

Gene sequence:

>762_bases
ATGACAAAGCCGTTCAGCTCCGTCCTGATCACCGGCGCCTCGTCGGGCCTGGGAGCCGGGCTGGCGCGGATCTGCGCGGC
GCCCGGCGTCACCTTGCACCTGTCGGGCCGCGACCGGAACCGCCTCGACGCGGCGGCGAAGCAGTGCGAAGCGCTGGGAG
CGGCTGTCCACGCCACCCCGTTGGACGTCACCGATTCAGCCGCCACGGCGCGCTGGGTCACGGATTCCGACGCCATCCGG
CCGCTGGATCTGGTCATCGCCAATGCCGGCATCTCGGCGGGCACCGGCGGCGGCGGCGAGACGGAGGCCCAGACCCGGGC
CATCTTCGCCGTCAATGTGAACGGCGTGTTCAACACGGTGATGCCCGCCATTCCCCTGCTGCGGCAACGCCGCCGGGGGC
AGGTCGGCATCATGAGTTCCCTGGCGGGCTTTCGCGGCTTTGCCGGAGCGCCCGCCTATTGCGCCTCCAAGGCCGCAATC
AGGGTCTGGGGCGAATCCCTGCGCGCCGAGCTGGCCCCCGCCGGCATCGGCGTCTCGGTGATCTGCCCCGGCTTCGTGGA
GACGCCCATGACGGCGGTGAACCGGTTCCGCATGCCGTTCCTGATGGACGTGGAGCGGGCCAGCCGCATCATGGTTCGCG
GACTGGCCCGCAACCGGGGCCGCATCGCCTTTCCCTGGCCCATGCACCTGATGGCCCGCCTGGCGGGGTGCCTGCCCAGC
GCGCTGATGGACCGCATCGCGGCGGGATTGCCGAGGAAGTAG

Upstream 100 bases:

>100_bases
TCTTCGACACCGCCCGCCACGACCTGCCGCCCCTGCTGGGGCCGCTGCGCGCCCTGCTCAACGAGCGGAACGGCAATGGC
AACGGGAACGGCAACGGCGG

Downstream 100 bases:

>100_bases
GGGGCCCCTACTTCACCGCCTCCATGCTGAATTCCTTGAATACCAGGGCCTCCACATAGACCCGGTCGGACGGCACCGCC
ACGCCGGCCCGGCGGTCATA

Product: dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MTKPFSSVLITGASSGLGAGLARICAAPGVTLHLSGRDRNRLDAAAKQCEALGAAVHATPLDVTDSAATARWVTDSDAIR
PLDLVIANAGISAGTGGGGETEAQTRAIFAVNVNGVFNTVMPAIPLLRQRRRGQVGIMSSLAGFRGFAGAPAYCASKAAI
RVWGESLRAELAPAGIGVSVICPGFVETPMTAVNRFRMPFLMDVERASRIMVRGLARNRGRIAFPWPMHLMARLAGCLPS
ALMDRIAAGLPRK

Sequences:

>Translated_253_residues
MTKPFSSVLITGASSGLGAGLARICAAPGVTLHLSGRDRNRLDAAAKQCEALGAAVHATPLDVTDSAATARWVTDSDAIR
PLDLVIANAGISAGTGGGGETEAQTRAIFAVNVNGVFNTVMPAIPLLRQRRRGQVGIMSSLAGFRGFAGAPAYCASKAAI
RVWGESLRAELAPAGIGVSVICPGFVETPMTAVNRFRMPFLMDVERASRIMVRGLARNRGRIAFPWPMHLMARLAGCLPS
ALMDRIAAGLPRK
>Mature_252_residues
TKPFSSVLITGASSGLGAGLARICAAPGVTLHLSGRDRNRLDAAAKQCEALGAAVHATPLDVTDSAATARWVTDSDAIRP
LDLVIANAGISAGTGGGGETEAQTRAIFAVNVNGVFNTVMPAIPLLRQRRRGQVGIMSSLAGFRGFAGAPAYCASKAAIR
VWGESLRAELAPAGIGVSVICPGFVETPMTAVNRFRMPFLMDVERASRIMVRGLARNRGRIAFPWPMHLMARLAGCLPSA
LMDRIAAGLPRK

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI210032110, Length=246, Percent_Identity=26.0162601626016, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI150247226, Length=216, Percent_Identity=32.8703703703704, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI7706318, Length=254, Percent_Identity=28.740157480315, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI142976729, Length=257, Percent_Identity=28.0155642023346, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI20149619, Length=196, Percent_Identity=31.1224489795918, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI4503817, Length=193, Percent_Identity=29.5336787564767, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI40807363, Length=241, Percent_Identity=28.6307053941909, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI7657478, Length=188, Percent_Identity=30.8510638297872, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI33667109, Length=215, Percent_Identity=27.4418604651163, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI31543615, Length=220, Percent_Identity=24.0909090909091, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI223718074, Length=192, Percent_Identity=32.8125, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI87082100, Length=187, Percent_Identity=32.0855614973262, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787335, Length=187, Percent_Identity=30.4812834224599, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790717, Length=187, Percent_Identity=27.2727272727273, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787820, Length=188, Percent_Identity=26.5957446808511, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193203115, Length=248, Percent_Identity=26.2096774193548, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193203117, Length=248, Percent_Identity=26.2096774193548, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17508895, Length=246, Percent_Identity=26.4227642276423, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=241, Percent_Identity=24.896265560166, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17567345, Length=223, Percent_Identity=26.9058295964126, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=197, Percent_Identity=28.4263959390863, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=187, Percent_Identity=32.0855614973262, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI32563809, Length=200, Percent_Identity=29.5, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17507613, Length=200, Percent_Identity=29.5, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=187, Percent_Identity=25.668449197861, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=188, Percent_Identity=26.5957446808511, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=190, Percent_Identity=28.9473684210526, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=199, Percent_Identity=30.6532663316583, Blast_Score=90, Evalue=3e-19,
Organism=Drosophila melanogaster, GI23397609, Length=184, Percent_Identity=36.4130434782609, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21355319, Length=185, Percent_Identity=27.027027027027, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21358495, Length=193, Percent_Identity=32.1243523316062, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24644339, Length=188, Percent_Identity=32.9787234042553, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28571526, Length=188, Percent_Identity=32.4468085106383, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21357041, Length=185, Percent_Identity=28.6486486486486, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24643142, Length=188, Percent_Identity=33.5106382978723, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24580925, Length=193, Percent_Identity=30.5699481865285, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26433; Mature: 26302

Theoretical pI: Translated: 11.57; Mature: 11.57

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPFSSVLITGASSGLGAGLARICAAPGVTLHLSGRDRNRLDAAAKQCEALGAAVHATP
CCCCCCCEEEECCCCCHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCC
LDVTDSAATARWVTDSDAIRPLDLVIANAGISAGTGGGGETEAQTRAIFAVNVNGVFNTV
CCCCCCCCCEEEECCCCCCCHHHHEEEECCCCCCCCCCCCCCCCEEEEEEEECCHHHHHH
MPAIPLLRQRRRGQVGIMSSLAGFRGFAGAPAYCASKAAIRVWGESLRAELAPAGIGVSV
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
ICPGFVETPMTAVNRFRMPFLMDVERASRIMVRGLARNRGRIAFPWPMHLMARLAGCLPS
ECCCHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHH
ALMDRIAAGLPRK
HHHHHHHHCCCCC
>Mature Secondary Structure 
TKPFSSVLITGASSGLGAGLARICAAPGVTLHLSGRDRNRLDAAAKQCEALGAAVHATP
CCCCCCEEEECCCCCHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCC
LDVTDSAATARWVTDSDAIRPLDLVIANAGISAGTGGGGETEAQTRAIFAVNVNGVFNTV
CCCCCCCCCEEEECCCCCCCHHHHEEEECCCCCCCCCCCCCCCCEEEEEEEECCHHHHHH
MPAIPLLRQRRRGQVGIMSSLAGFRGFAGAPAYCASKAAIRVWGESLRAELAPAGIGVSV
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
ICPGFVETPMTAVNRFRMPFLMDVERASRIMVRGLARNRGRIAFPWPMHLMARLAGCLPS
ECCCHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHH
ALMDRIAAGLPRK
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1730672 [H]