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The map label for this gene is trxB [H]

Identifier: 83309762

GI number: 83309762

Start: 714464

End: 715414

Strand: Reverse

Name: trxB [H]

Synonym: amb0663

Alternate gene names: 83309762

Gene position: 715414-714464 (Counterclockwise)

Preceding gene: 83309763

Following gene: 83309761

Centisome position: 14.4

GC content: 66.56

Gene sequence:

>951_bases
ATGGCGCATCACCACTCCAAGGTCCTGATTCTGGGTTCCGGTCCGGCCGGCTGCACCGCGGCCATCTACGCGGCGCGCGC
CAATCTCGAGCCCATGCTGGTGGCCGGGCTGCAGCCCGGCGGCCAGTTGACCATCACCACTGATGTGGAAAACTTCCCAG
GCTTCGCCGAGGCGGTCCAGGGGCCCTGGCTGATGGAACAGATGCAGGCCCAGGCCGAGCATGTGGGCACCCGCTTCATG
GACGACACCATCGTCTCGGTGGACCTGTCCAAGCGCCCCTTCACCGCCGTGGGCGATTCCGGCGACACCTATGCCGGCGA
TACGCTGATCATCTGCACCGGCGCCACCGCCCGCTGGCTGGGCCTGGAATCGGAAAAGAAGTTCTCCGGCTTCGGCGTGT
CGGCTTGCGCCACCTGCGACGGCTTCTTCTTCCGCGGCAAGGAAGTGGCGGTGATGGGCGGCGGCAATTCGGCGGTGGAA
GAGGCCATCTATCTGGCCGGCATCGCCTCCAAGGTCACCCTGATCCATCGCCGCGACACGCTGCGGGCCGAAAAGATCGC
CCAGGACCGCCTGTTCGCCAATCCCAAGGTCGCCGTGGTCTGGGACAGCGTCATCGACGAGATCGTCGGCGACGACAACC
CTCCTGGCGTCACCGGGGTGCGCCTCAAGAACGTCAAGACCGGCGCGCTGTCCGTGCTGCCAGTGGACGGCGTGTTCATC
GCCATCGGCCACACGCCCAACACCGAGCTGTTCAAGGGCGCCCTGGAAATGGATTCCGAGGGCTATCTGATCACCAAGGC
CGGCGCCACCTCCACCAACATTCCCGGCGTGTTCGCCGCCGGCGACGTGCAGGACAAGATCTATCGCCAGGCGGTCACCG
CCGCCGGCACCGGCTGCATGGCCGCGCTGGAGGCCGAGCGCTTCCTCACCGCGCATGGACACACGGGTTAA

Upstream 100 bases:

>100_bases
TAAGGCTTTTGTAAGATAGGGAGGGCGCGCCGCTTGCCAGCGGCGCGCCCTCTCCTTATGCTGTGACGCAATAATTTCGA
AAAGTCCGGGAAGCATCGCG

Downstream 100 bases:

>100_bases
GTTGCGGCACAGTAGCCGGTATGAAATGGGAGGGCGGAAACCATAATCCGCCGCGGGGAGGAGACCGGTCGCCACATGGA
CTGGGATAAGCTGAGGGTTT

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MAHHHSKVLILGSGPAGCTAAIYAARANLEPMLVAGLQPGGQLTITTDVENFPGFAEAVQGPWLMEQMQAQAEHVGTRFM
DDTIVSVDLSKRPFTAVGDSGDTYAGDTLIICTGATARWLGLESEKKFSGFGVSACATCDGFFFRGKEVAVMGGGNSAVE
EAIYLAGIASKVTLIHRRDTLRAEKIAQDRLFANPKVAVVWDSVIDEIVGDDNPPGVTGVRLKNVKTGALSVLPVDGVFI
AIGHTPNTELFKGALEMDSEGYLITKAGATSTNIPGVFAAGDVQDKIYRQAVTAAGTGCMAALEAERFLTAHGHTG

Sequences:

>Translated_316_residues
MAHHHSKVLILGSGPAGCTAAIYAARANLEPMLVAGLQPGGQLTITTDVENFPGFAEAVQGPWLMEQMQAQAEHVGTRFM
DDTIVSVDLSKRPFTAVGDSGDTYAGDTLIICTGATARWLGLESEKKFSGFGVSACATCDGFFFRGKEVAVMGGGNSAVE
EAIYLAGIASKVTLIHRRDTLRAEKIAQDRLFANPKVAVVWDSVIDEIVGDDNPPGVTGVRLKNVKTGALSVLPVDGVFI
AIGHTPNTELFKGALEMDSEGYLITKAGATSTNIPGVFAAGDVQDKIYRQAVTAAGTGCMAALEAERFLTAHGHTG
>Mature_315_residues
AHHHSKVLILGSGPAGCTAAIYAARANLEPMLVAGLQPGGQLTITTDVENFPGFAEAVQGPWLMEQMQAQAEHVGTRFMD
DTIVSVDLSKRPFTAVGDSGDTYAGDTLIICTGATARWLGLESEKKFSGFGVSACATCDGFFFRGKEVAVMGGGNSAVEE
AIYLAGIASKVTLIHRRDTLRAEKIAQDRLFANPKVAVVWDSVIDEIVGDDNPPGVTGVRLKNVKTGALSVLPVDGVFIA
IGHTPNTELFKGALEMDSEGYLITKAGATSTNIPGVFAAGDVQDKIYRQAVTAAGTGCMAALEAERFLTAHGHTG

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=313, Percent_Identity=57.1884984025559, Blast_Score=345, Evalue=3e-96,
Organism=Escherichia coli, GI87081763, Length=311, Percent_Identity=36.9774919614148, Blast_Score=146, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6321898, Length=322, Percent_Identity=46.583850931677, Blast_Score=283, Evalue=3e-77,
Organism=Saccharomyces cerevisiae, GI6320560, Length=317, Percent_Identity=45.7413249211356, Blast_Score=279, Evalue=4e-76,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33129; Mature: 32998

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHHHSKVLILGSGPAGCTAAIYAARANLEPMLVAGLQPGGQLTITTDVENFPGFAEAVQ
CCCCCCEEEEEECCCCCHHHEEEHHHCCCCEEEEEECCCCCEEEEEECCCCCCCHHHHHC
GPWLMEQMQAQAEHVGTRFMDDTIVSVDLSKRPFTAVGDSGDTYAGDTLIICTGATARWL
CCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEECCCCCCCCCCEEEEECCCCEEEE
GLESEKKFSGFGVSACATCDGFFFRGKEVAVMGGGNSAVEEAIYLAGIASKVTLIHRRDT
CCCCCCCCCCCCCHHHHCCCCEEECCCEEEEEECCCHHHHHHHHHHHHHHEEEEEECCCH
LRAEKIAQDRLFANPKVAVVWDSVIDEIVGDDNPPGVTGVRLKNVKTGALSVLPVDGVFI
HHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEECCEEE
AIGHTPNTELFKGALEMDSEGYLITKAGATSTNIPGVFAAGDVQDKIYRQAVTAAGTGCM
EECCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCHH
AALEAERFLTAHGHTG
HHHHHHHEEEECCCCC
>Mature Secondary Structure 
AHHHSKVLILGSGPAGCTAAIYAARANLEPMLVAGLQPGGQLTITTDVENFPGFAEAVQ
CCCCCEEEEEECCCCCHHHEEEHHHCCCCEEEEEECCCCCEEEEEECCCCCCCHHHHHC
GPWLMEQMQAQAEHVGTRFMDDTIVSVDLSKRPFTAVGDSGDTYAGDTLIICTGATARWL
CCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEECCCCCCCCCCEEEEECCCCEEEE
GLESEKKFSGFGVSACATCDGFFFRGKEVAVMGGGNSAVEEAIYLAGIASKVTLIHRRDT
CCCCCCCCCCCCCHHHHCCCCEEECCCEEEEEECCCHHHHHHHHHHHHHHEEEEEECCCH
LRAEKIAQDRLFANPKVAVVWDSVIDEIVGDDNPPGVTGVRLKNVKTGALSVLPVDGVFI
HHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEECCEEE
AIGHTPNTELFKGALEMDSEGYLITKAGATSTNIPGVFAAGDVQDKIYRQAVTAAGTGCM
EECCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCHH
AALEAERFLTAHGHTG
HHHHHHHEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA