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The map label for this gene is cobC [C]

Identifier: 83309640

GI number: 83309640

Start: 588736

End: 589347

Strand: Reverse

Name: cobC [C]

Synonym: amb0541

Alternate gene names: 83309640

Gene position: 589347-588736 (Counterclockwise)

Preceding gene: 83309646

Following gene: 83309636

Centisome position: 11.86

GC content: 72.71

Gene sequence:

>612_bases
ATGAGTTCCCATTCCACCCGCTGGTGGCTGCTGCGCCACGCTCCGGTCCCCTGCCCCCACGGCCGCATCACCGGCCGCCT
GGACGTGGCGTGCGACACCTCGGAGGACGAGGTCTTCCAGTCCCTGGCCCGCGCCCTGCCGGTCAATCCGGTCCTGGTGG
AAAGCGGCCTGATCCGCTGCCGCCAGACGGCGGGGGCGCTGGAGGCCGGCGGCTTGCTGCTGCCGCCGCCCATGGTCGAG
CCCGATCTGGCCGAGCAGGATTTCGGCCGCTGGCAGGGGCGGTCATGGATGGAACTGGAAGCCGCCAAGGACCCGGACCT
CGCCGCCTTCTGGGCCGACCCGGCCACCGCCACCCCGCCCGGGGGCGAAAGTTTCGCCGCCATGGTGGAGCGGGTCCGCG
CCGCCGTGGAGCAGATCACCGCCGCCCAGGCGGGGCGCGATATCCTGGCCGTGGTGCATGCGGGAACGGTCCGCGCCGCC
CTGGCGGTGGCGCTGGATCTCAAGCCGGAACAGGCGCTGCGCGTCGCGGTCAAGCCGCTGTCACTGACCCGCCTCGACGC
CACGGCTTCGGGCTGGCGCGTCGAAATGGTCAACGCCCAGCCCTATGCCTGA

Upstream 100 bases:

>100_bases
CACGGCGCGCCCTGGGCGGCTATACCGGCGACGTGCTGGGCGCCGTGCAACAAGCCACAGAGATCGGCGTCCTGCTGGCC
GCCGCAGGAGTCCTTAGTCC

Downstream 100 bases:

>100_bases
GGCCCGAGGGGGAGCCCCCCTCGGAGCCCAGGATCAGAATTTCACCGTCACCCCGGCGTTGAACGACCGGCCCGGCGCCG
GCAGGGCGCCCACCTGGCCG

Product: fructose-2,6-bisphosphatase

Products: NA

Alternate protein names: Phosphoglycerate Mutase Family Protein; Phosphoglycerate/Bisphosphoglycerate Mutase; Alpha-Ribazole Phosphatase; Alpha-Ribazole-5-Phosphate Phosphatase; Alpha-Ribazole-5`-Phosphate Phosphatase CobC; Fructose-2 6-Bisphosphatase; Alpha-Ribazole-5-Phosphate Phosphatase CobC; Cobalamin Synthesis Protein

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MSSHSTRWWLLRHAPVPCPHGRITGRLDVACDTSEDEVFQSLARALPVNPVLVESGLIRCRQTAGALEAGGLLLPPPMVE
PDLAEQDFGRWQGRSWMELEAAKDPDLAAFWADPATATPPGGESFAAMVERVRAAVEQITAAQAGRDILAVVHAGTVRAA
LAVALDLKPEQALRVAVKPLSLTRLDATASGWRVEMVNAQPYA

Sequences:

>Translated_203_residues
MSSHSTRWWLLRHAPVPCPHGRITGRLDVACDTSEDEVFQSLARALPVNPVLVESGLIRCRQTAGALEAGGLLLPPPMVE
PDLAEQDFGRWQGRSWMELEAAKDPDLAAFWADPATATPPGGESFAAMVERVRAAVEQITAAQAGRDILAVVHAGTVRAA
LAVALDLKPEQALRVAVKPLSLTRLDATASGWRVEMVNAQPYA
>Mature_202_residues
SSHSTRWWLLRHAPVPCPHGRITGRLDVACDTSEDEVFQSLARALPVNPVLVESGLIRCRQTAGALEAGGLLLPPPMVEP
DLAEQDFGRWQGRSWMELEAAKDPDLAAFWADPATATPPGGESFAAMVERVRAAVEQITAAQAGRDILAVVHAGTVRAAL
AVALDLKPEQALRVAVKPLSLTRLDATASGWRVEMVNAQPYA

Specific function: Converts N1-(5-Phospho-Alpha-D-Ribosyl)-5,6- Dimethylbenzimidazole Into N1-Alpha-D-Ribosyl-5,6- Dimethylbenzimidazole; Involved In The Assembly Of The Nucleotide Loop Of Cobalamin. [C]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.3.73 [C]

Molecular weight: Translated: 21803; Mature: 21672

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSHSTRWWLLRHAPVPCPHGRITGRLDVACDTSEDEVFQSLARALPVNPVLVESGLIRC
CCCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCEEHHHHHHHH
RQTAGALEAGGLLLPPPMVEPDLAEQDFGRWQGRSWMELEAAKDPDLAAFWADPATATPP
HHHCCCCCCCCEECCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCEEEEECCCCCCCCC
GGESFAAMVERVRAAVEQITAAQAGRDILAVVHAGTVRAALAVALDLKPEQALRVAVKPL
CCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHCCC
SLTRLDATASGWRVEMVNAQPYA
EEEEECCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
SSHSTRWWLLRHAPVPCPHGRITGRLDVACDTSEDEVFQSLARALPVNPVLVESGLIRC
CCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCEEHHHHHHHH
RQTAGALEAGGLLLPPPMVEPDLAEQDFGRWQGRSWMELEAAKDPDLAAFWADPATATPP
HHHCCCCCCCCEECCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCEEEEECCCCCCCCC
GGESFAAMVERVRAAVEQITAAQAGRDILAVVHAGTVRAALAVALDLKPEQALRVAVKPL
CCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHCCC
SLTRLDATASGWRVEMVNAQPYA
EEEEECCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA