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The map label for this gene is argJ [H]

Identifier: 83309609

GI number: 83309609

Start: 546435

End: 547667

Strand: Reverse

Name: argJ [H]

Synonym: amb0510

Alternate gene names: 83309609

Gene position: 547667-546435 (Counterclockwise)

Preceding gene: 83309610

Following gene: 83309608

Centisome position: 11.03

GC content: 68.61

Gene sequence:

>1233_bases
ATGACCACCGCCATCTCCCCCCTCGCCCCCGAGCGCTTCCCCGACATGCCCGTCATCGCCGGCATCCGGCTGGCCAGCCA
CGCCTGCGGCGTGCGCTATGCCGGACGCACCGACCTGCTGATGGTCGAGATGGACAAGGGCACCACGGCCGCCGGCGTCT
TCACCCGCTCGCTGACCGCCTCCGCCCCGGTGGAATGGTGCCGCGCCGCCGTGGCCAAGGGCTCGGCCCGCGCCCTGGTG
GTCAATTCCGGCAATGCCAACGCCTTCACCGGCTCGGTGGGCGTGGCCTCGGTCAAGCGCACGGTGGAGTCCACCGCCGC
CCTGGTGGGCTGCAAGGACTCCGAGGTCTACATCGCGTCGACCGGCACCATCGGCGTGCGCCTGCCCGACGAGAAGATCA
CCGCCGCCCTGGGCGACGTGCGCGCCAAGCTGCAGCCCGGCAACTGGCTGGAGGCCGCCCAGGCCATCATGACCACCGAC
ACCTACCCCAAGGGCGCCAGCCGCACGGCGGTGATCGACGGCACCACGGTGATCATCAACGGCATCGCCAAGGGCGCCGG
CATGATCGCGCCCGACATGGCCACCATGCTGTCCTACGTCTTCACCGACGCCGCCCTGCCGGCCGAGGTGCTGCAGGACC
TGCTGAGCAAGGGCGTGGACAAGTCGTTCAACGCCATCACCGTGGATTCCGACACCTCGACCAGCGACACCCTGATGCTG
TTCGCCACGGGCAAGGCCGGCAACAAGGTGATCAAGGACGCCAAGGACAAGCGCCTGGCCGATTTCAAGGCCAAGCTGTT
CGACCTGCTGCTCGACCTGGCCCTGCAGGTGGTCCGGGACGGCGAGGGCGCCACCAAGTTCGTCACCATCCACGTGACCG
GCGCCGCCGGCAAGAAGGCGGCGCGGACCATCGGCATGTCCATCGCCAACTCCCCCCTGGTCAAGACCGCCATCGCCGGC
GAGGACGCCAATTGGGGTCGCGTGGTCGCCGCCGTCGGCAAGGCCGGCGAGAAGGCCAACCGCGACCGGCTCTCCATCCG
CATGGGCGGCGTGCTGGTGGCCGACAAGGGCGAAATGGCCCACGGCTATGACGAGGCCCCGGTGGCCGCCCACTTCAAGG
GCAAGGACATCGTCATCGAGGTGGATGTGGGCGTGGGCAAGGGACGGTCGACCGTCTATACTTGCGACCTGACGCACGCG
TATATCGACATCAATGGGTCCTATCGGACCTGA

Upstream 100 bases:

>100_bases
CGACGGCACGCCGCTCGAAGCGGCCAAGAAGTAAAAGCCTGAATGGCCCGGCCGTCGAAAACGGCCGGGCCTTTTACCCT
GCGACAACGGATTTCCCGCC

Downstream 100 bases:

>100_bases
GGAACGGAGACGGCATCATGGCGGAGCGGGGTTGCCGGGAACCGGGCACGGTCTGGGCGGGTCATCCCCTGCTCACGGCC
CGTCTGCGCCTGCGGCCGGT

Product: N-acetylglutamate synthase

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS [H]

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MTTAISPLAPERFPDMPVIAGIRLASHACGVRYAGRTDLLMVEMDKGTTAAGVFTRSLTASAPVEWCRAAVAKGSARALV
VNSGNANAFTGSVGVASVKRTVESTAALVGCKDSEVYIASTGTIGVRLPDEKITAALGDVRAKLQPGNWLEAAQAIMTTD
TYPKGASRTAVIDGTTVIINGIAKGAGMIAPDMATMLSYVFTDAALPAEVLQDLLSKGVDKSFNAITVDSDTSTSDTLML
FATGKAGNKVIKDAKDKRLADFKAKLFDLLLDLALQVVRDGEGATKFVTIHVTGAAGKKAARTIGMSIANSPLVKTAIAG
EDANWGRVVAAVGKAGEKANRDRLSIRMGGVLVADKGEMAHGYDEAPVAAHFKGKDIVIEVDVGVGKGRSTVYTCDLTHA
YIDINGSYRT

Sequences:

>Translated_410_residues
MTTAISPLAPERFPDMPVIAGIRLASHACGVRYAGRTDLLMVEMDKGTTAAGVFTRSLTASAPVEWCRAAVAKGSARALV
VNSGNANAFTGSVGVASVKRTVESTAALVGCKDSEVYIASTGTIGVRLPDEKITAALGDVRAKLQPGNWLEAAQAIMTTD
TYPKGASRTAVIDGTTVIINGIAKGAGMIAPDMATMLSYVFTDAALPAEVLQDLLSKGVDKSFNAITVDSDTSTSDTLML
FATGKAGNKVIKDAKDKRLADFKAKLFDLLLDLALQVVRDGEGATKFVTIHVTGAAGKKAARTIGMSIANSPLVKTAIAG
EDANWGRVVAAVGKAGEKANRDRLSIRMGGVLVADKGEMAHGYDEAPVAAHFKGKDIVIEVDVGVGKGRSTVYTCDLTHA
YIDINGSYRT
>Mature_409_residues
TTAISPLAPERFPDMPVIAGIRLASHACGVRYAGRTDLLMVEMDKGTTAAGVFTRSLTASAPVEWCRAAVAKGSARALVV
NSGNANAFTGSVGVASVKRTVESTAALVGCKDSEVYIASTGTIGVRLPDEKITAALGDVRAKLQPGNWLEAAQAIMTTDT
YPKGASRTAVIDGTTVIINGIAKGAGMIAPDMATMLSYVFTDAALPAEVLQDLLSKGVDKSFNAITVDSDTSTSDTLMLF
ATGKAGNKVIKDAKDKRLADFKAKLFDLLLDLALQVVRDGEGATKFVTIHVTGAAGKKAARTIGMSIANSPLVKTAIAGE
DANWGRVVAAVGKAGEKANRDRLSIRMGGVLVADKGEMAHGYDEAPVAAHFKGKDIVIEVDVGVGKGRSTVYTCDLTHAY
IDINGSYRT

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate [H]

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=417, Percent_Identity=37.8896882494005, Blast_Score=236, Evalue=7e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002813
- InterPro:   IPR016117 [H]

Pfam domain/function: PF01960 ArgJ [H]

EC number: =2.3.1.35; =2.3.1.1 [H]

Molecular weight: Translated: 42670; Mature: 42539

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAISPLAPERFPDMPVIAGIRLASHACGVRYAGRTDLLMVEMDKGTTAAGVFTRSLTA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCEEECCCCCEEEEEECCCCEEHHEEEECCCC
SAPVEWCRAAVAKGSARALVVNSGNANAFTGSVGVASVKRTVESTAALVGCKDSEVYIAS
CCCHHHHHHHHHCCCCEEEEEECCCCCEEECCCHHHHHHHHHHHHHHEEECCCCCEEEEE
TGTIGVRLPDEKITAALGDVRAKLQPGNWLEAAQAIMTTDTYPKGASRTAVIDGTTVIIN
CCEEEEEECCHHHHHHHHHHHEECCCCCHHHHHHHHHCCCCCCCCCCCEEEECCCEEEEE
GIAKGAGMIAPDMATMLSYVFTDAALPAEVLQDLLSKGVDKSFNAITVDSDTSTSDTLML
ECCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEEE
FATGKAGNKVIKDAKDKRLADFKAKLFDLLLDLALQVVRDGEGATKFVTIHVTGAAGKKA
EEECCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCHH
ARTIGMSIANSPLVKTAIAGEDANWGRVVAAVGKAGEKANRDRLSIRMGGVLVADKGEMA
HHHHHHHHCCCCCEEEEECCCCCCCCHHEEECCCCCCCCCCCEEEEEECCEEEECCCCCC
HGYDEAPVAAHFKGKDIVIEVDVGVGKGRSTVYTCDLTHAYIDINGSYRT
CCCCCCCEEEEECCCEEEEEEECCCCCCCCEEEEEEEEEEEEEECCCCCC
>Mature Secondary Structure 
TTAISPLAPERFPDMPVIAGIRLASHACGVRYAGRTDLLMVEMDKGTTAAGVFTRSLTA
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCEEECCCCCEEEEEECCCCEEHHEEEECCCC
SAPVEWCRAAVAKGSARALVVNSGNANAFTGSVGVASVKRTVESTAALVGCKDSEVYIAS
CCCHHHHHHHHHCCCCEEEEEECCCCCEEECCCHHHHHHHHHHHHHHEEECCCCCEEEEE
TGTIGVRLPDEKITAALGDVRAKLQPGNWLEAAQAIMTTDTYPKGASRTAVIDGTTVIIN
CCEEEEEECCHHHHHHHHHHHEECCCCCHHHHHHHHHCCCCCCCCCCCEEEECCCEEEEE
GIAKGAGMIAPDMATMLSYVFTDAALPAEVLQDLLSKGVDKSFNAITVDSDTSTSDTLML
ECCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEEE
FATGKAGNKVIKDAKDKRLADFKAKLFDLLLDLALQVVRDGEGATKFVTIHVTGAAGKKA
EEECCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCHH
ARTIGMSIANSPLVKTAIAGEDANWGRVVAAVGKAGEKANRDRLSIRMGGVLVADKGEMA
HHHHHHHHCCCCCEEEEECCCCCCCCHHEEECCCCCCCCCCCEEEEEECCEEEECCCCCC
HGYDEAPVAAHFKGKDIVIEVDVGVGKGRSTVYTCDLTHAYIDINGSYRT
CCCCCCCEEEEECCCEEEEEEECCCCCCCCEEEEEEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]