Click here to switch to the map view.

The map label for this gene is icaR

Identifier: 82752243

GI number: 82752243

Start: 2696628

End: 2697188

Strand: Reverse

Name: icaR

Synonym: SAB2540c

Alternate gene names: 82752243

Gene position: 2697188-2696628 (Counterclockwise)

Preceding gene: 82752248

Following gene: 82752242

Centisome position: 98.35

GC content: 27.45

Gene sequence:

>561_bases
TTGAAGGATAAGATTATTGATAACGCAATAACCTTATTTTCAGAGAAGGGGTATGACGGTACAACACTTGATGATATAGC
TAAAAGTGTAAATATAAAAAAAGCGAGTTTATATTACCATTTTGACTCGAAAAAAAGTATTTACGAACAAAGTGTTAAAT
GCTGTTTTGATTACCTTAATAATATTATTATGATGAATCAAAATAAATCGAACTATTCAATTGATGCTTTATATCAATTC
TTATTTGAGTTTATTTTCGACATCGAAGAAAGGTATATTAGAATGTACGTTCAATTATCTAATACGCCTGAGGAATTTTC
TGGAAATATTTACGGACAAATACAAGATTTAAATCAATCGTTAAGTAAAGAGATAGCAAAATTCTATGATGAATCAAAGA
TAAAGATGACAAAAGAAGACTTTCAGAATTTAATATTGCTGTTTCTTGAAAGTTGGTATTTGAAAGCATCCTTTTCGCAA
AAATTTGGAGCAATGGAAGAAAGTAAAAGTCAATTCAAAGATGAAGTGTATTCGCTACTAAATATATTTTTGAAGAAATA
A

Upstream 100 bases:

>100_bases
TGCAATAGATTGTTGTTATAATTAAACGGAAATATTTGTAATTGCAACTTAATTTTCCTGTAACATAGTGTGATTAATTT
TCAGTAGGGGGTTATAAAAA

Downstream 100 bases:

>100_bases
TTTTTGTTATTAGTTTGTAATAATTAACTTACTTTTGTAAAAAAAGACATGAGATTATTTTTTTAAATCTATATAAAGTT
GACAATACAACTCGAAATTG

Product: ica operon transcription regulator

Products: NA

Alternate protein names: Intercellular adhesion protein R [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MKDKIIDNAITLFSEKGYDGTTLDDIAKSVNIKKASLYYHFDSKKSIYEQSVKCCFDYLNNIIMMNQNKSNYSIDALYQF
LFEFIFDIEERYIRMYVQLSNTPEEFSGNIYGQIQDLNQSLSKEIAKFYDESKIKMTKEDFQNLILLFLESWYLKASFSQ
KFGAMEESKSQFKDEVYSLLNIFLKK

Sequences:

>Translated_186_residues
MKDKIIDNAITLFSEKGYDGTTLDDIAKSVNIKKASLYYHFDSKKSIYEQSVKCCFDYLNNIIMMNQNKSNYSIDALYQF
LFEFIFDIEERYIRMYVQLSNTPEEFSGNIYGQIQDLNQSLSKEIAKFYDESKIKMTKEDFQNLILLFLESWYLKASFSQ
KFGAMEESKSQFKDEVYSLLNIFLKK
>Mature_186_residues
MKDKIIDNAITLFSEKGYDGTTLDDIAKSVNIKKASLYYHFDSKKSIYEQSVKCCFDYLNNIIMMNQNKSNYSIDALYQF
LFEFIFDIEERYIRMYVQLSNTPEEFSGNIYGQIQDLNQSLSKEIAKFYDESKIKMTKEDFQNLILLFLESWYLKASFSQ
KFGAMEESKSQFKDEVYSLLNIFLKK

Specific function: Represses transcription of the icaADBC operon necessary for biofilm production [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22019; Mature: 22019

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDKIIDNAITLFSEKGYDGTTLDDIAKSVNIKKASLYYHFDSKKSIYEQSVKCCFDYLN
CCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHHHHHHC
NIIMMNQNKSNYSIDALYQFLFEFIFDIEERYIRMYVQLSNTPEEFSGNIYGQIQDLNQS
CEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHH
LSKEIAKFYDESKIKMTKEDFQNLILLFLESWYLKASFSQKFGAMEESKSQFKDEVYSLL
HHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
NIFLKK
HHHHCC
>Mature Secondary Structure
MKDKIIDNAITLFSEKGYDGTTLDDIAKSVNIKKASLYYHFDSKKSIYEQSVKCCFDYLN
CCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHHHHHHC
NIIMMNQNKSNYSIDALYQFLFEFIFDIEERYIRMYVQLSNTPEEFSGNIYGQIQDLNQS
CEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHH
LSKEIAKFYDESKIKMTKEDFQNLILLFLESWYLKASFSQKFGAMEESKSQFKDEVYSLL
HHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
NIFLKK
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10496925 [H]