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The map label for this gene is arsR

Identifier: 82751358

GI number: 82751358

Start: 1777627

End: 1777941

Strand: Direct

Name: arsR

Synonym: SAB1630

Alternate gene names: 82751358

Gene position: 1777627-1777941 (Clockwise)

Preceding gene: 82751352

Following gene: 82751359

Centisome position: 64.82

GC content: 30.79

Gene sequence:

>315_bases
ATGACGTATAAAGAACTAGCAACATATTTAAAAGTTTTATCAGATTCAAGCAGATTAGAAATACTAGATTTACTTTCTTG
TGGAGAGTTATGTGCTTGTGATTTGTTAGAACATTTTCAATTCTCTCAACCCACACTTAGCTATCATATGAAAGCATTAG
TAAAAACCAACTTAGTTACGACACGAAAAATCGGAAATAAACATTTATACCAGCTTAATCATAATATTTTTGAGTCCGTA
ATTAATAACTTGTCTAAGGTTCATACCTCTAACCAACGATGTATTTGTCATAACCTTAAGACTGGTGAATGCTAA

Upstream 100 bases:

>100_bases
ACCAAATTTAGATTACATAGTCATATTCTGTAATATACCAGAGAAACATAGACATTCATCTATATAGATGATAATCTATT
TAACGTCTAGGAGGTATGTT

Downstream 100 bases:

>100_bases
TGATGACAACTTTAGCGACACTCATTTTTCTAGTAACTTTATTATTTGTATTATGGCAACCTAAAGGCCTAGATATTGGC
ATTACCGCATTAACTGGTGC

Product: arsenical resistance operon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 104; Mature: 103

Protein sequence:

>104_residues
MTYKELATYLKVLSDSSRLEILDLLSCGELCACDLLEHFQFSQPTLSYHMKALVKTNLVTTRKIGNKHLYQLNHNIFESV
INNLSKVHTSNQRCICHNLKTGEC

Sequences:

>Translated_104_residues
MTYKELATYLKVLSDSSRLEILDLLSCGELCACDLLEHFQFSQPTLSYHMKALVKTNLVTTRKIGNKHLYQLNHNIFESV
INNLSKVHTSNQRCICHNLKTGEC
>Mature_103_residues
TYKELATYLKVLSDSSRLEILDLLSCGELCACDLLEHFQFSQPTLSYHMKALVKTNLVTTRKIGNKHLYQLNHNIFESVI
NNLSKVHTSNQRCICHNLKTGEC

Specific function: Transcriptional repressor for the ars operon. ArsR is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsR is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenat

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 11915; Mature: 11784

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: PS00846 HTH_ARSR_1 ; PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
5.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYKELATYLKVLSDSSRLEILDLLSCGELCACDLLEHFQFSQPTLSYHMKALVKTNLVT
CCHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
TRKIGNKHLYQLNHNIFESVINNLSKVHTSNQRCICHNLKTGEC
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCC
>Mature Secondary Structure 
TYKELATYLKVLSDSSRLEILDLLSCGELCACDLLEHFQFSQPTLSYHMKALVKTNLVT
CHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
TRKIGNKHLYQLNHNIFESVINNLSKVHTSNQRCICHNLKTGEC
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1534328 [H]