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The map label for this gene is arsB

Identifier: 82751359

GI number: 82751359

Start: 1777941

End: 1779233

Strand: Direct

Name: arsB

Synonym: SAB1631

Alternate gene names: 82751359

Gene position: 1777941-1779233 (Clockwise)

Preceding gene: 82751358

Following gene: 82751360

Centisome position: 64.83

GC content: 31.25

Gene sequence:

>1293_bases
ATGATGACAACTTTAGCGACACTCATTTTTCTAGTAACTTTATTATTTGTATTATGGCAACCTAAAGGCCTAGATATTGG
CATTACCGCATTAACTGGTGCCTTTATTGCTATTATTACTGGTGTTGTAAGTTTTTCCGATGTTTTCGAAGTAACAGGTA
TTGTTTGGAATGCTACTTTGACTTTTGTCTCAGTCATTCTTATTTCATTAATATTAGATAAAGTTGGATTATTCGAATGG
TCAGCTATTCACATGCTTCATGCTTCAAAAGGCAATGGTTTAAAAATGTTCGTTTATATCATATTATTATGTGCCATTGT
TGCTGCATTTTTCGCAAATGATGGCGCAGCGTTAATCTTAACGCCTATTGTATTAGCGATGGTTAAAAATATTGGATTTA
ATAAGCGCGCAATATTTCCATTTATTATTGCAAGTGGTTTTATTGCTGATACAACGTCTTTACCTTTAATTGTAAGTAAT
CTAGTGAATATTATATCTGCCTATTATTTTCATGTAGGATTCGTTCGATATTTTAGTAGAATGTTTATACCTAATTTATT
CTCACTTTTAGCAAGTATTATAGTATTGTGGTTATATTTTAGAAAAGCGATACCTAAAACGTTTGATGATAATAATATAA
AGCGCCCTAAAGATGCTATTAATGATTTAAAGCTATTTAAAATTTCATGGATTGTTCTAGTTATATTACTTTTCGGCTAT
CTAATCAGTGAATTTACTAAAATTCCGGTATCAATTTTCACTGGAATCATTGCTTTTATATTTCTAATGTTGGCTCGTAA
ATCAAATGCTGTAAATATTAAGGAAGTCATTAAGGGCGCACCTTGGAATATAGTATTATTTTCAATTGGTATGTATATCG
TCGTATTCGGCTTAAGAAATGCTGGCATTACTTTAATATTGGCTAAAATATTAGAATATATTTCCAATTACGGTCTATTT
AGCACCATTTTGGGAATGGGCTTCATTTCAGCATTTTTATCATCAATAATGAATAATATGCCTACAGTTTTAATAGATGC
GATTGCTATTGGTCAATCAAATGTCCATGGCATGTTAAAAGAAGGCCTAATTTATGCGAATGTTATCGGTTCTGATTTAG
GCCCAAAAATTACACCGATAGGCTCTTTAGCTACATTACTGTGGTTACACGTCTTAACACAAAAAGATGTTAAGATTTCT
TGGGGCACATACTTTAAAACTGGTATCATCTTTACAATTCCAGTACTATTTATAACCCTCATAGGGTTGTATCTAACACT
TATCATATTTTAA

Upstream 100 bases:

>100_bases
TTAATCATAATATTTTTGAGTCCGTAATTAATAACTTGTCTAAGGTTCATACCTCTAACCAACGATGTATTTGTCATAAC
CTTAAGACTGGTGAATGCTA

Downstream 100 bases:

>100_bases
TTAATTAGGAGATTGTTATGACTAAAAAAACAATTTATTTTATATGTACAGGCAACTCATGTCGAAGTCAAATGGCTGAA
GGTTGGGCTAAACAAATCTT

Product: arsenic efflux pump protein

Products: ADP; phosphate; arsenite [Periplasm] [C]

Alternate protein names: Arsenic efflux pump protein [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MMTTLATLIFLVTLLFVLWQPKGLDIGITALTGAFIAIITGVVSFSDVFEVTGIVWNATLTFVSVILISLILDKVGLFEW
SAIHMLHASKGNGLKMFVYIILLCAIVAAFFANDGAALILTPIVLAMVKNIGFNKRAIFPFIIASGFIADTTSLPLIVSN
LVNIISAYYFHVGFVRYFSRMFIPNLFSLLASIIVLWLYFRKAIPKTFDDNNIKRPKDAINDLKLFKISWIVLVILLFGY
LISEFTKIPVSIFTGIIAFIFLMLARKSNAVNIKEVIKGAPWNIVLFSIGMYIVVFGLRNAGITLILAKILEYISNYGLF
STILGMGFISAFLSSIMNNMPTVLIDAIAIGQSNVHGMLKEGLIYANVIGSDLGPKITPIGSLATLLWLHVLTQKDVKIS
WGTYFKTGIIFTIPVLFITLIGLYLTLIIF

Sequences:

>Translated_430_residues
MMTTLATLIFLVTLLFVLWQPKGLDIGITALTGAFIAIITGVVSFSDVFEVTGIVWNATLTFVSVILISLILDKVGLFEW
SAIHMLHASKGNGLKMFVYIILLCAIVAAFFANDGAALILTPIVLAMVKNIGFNKRAIFPFIIASGFIADTTSLPLIVSN
LVNIISAYYFHVGFVRYFSRMFIPNLFSLLASIIVLWLYFRKAIPKTFDDNNIKRPKDAINDLKLFKISWIVLVILLFGY
LISEFTKIPVSIFTGIIAFIFLMLARKSNAVNIKEVIKGAPWNIVLFSIGMYIVVFGLRNAGITLILAKILEYISNYGLF
STILGMGFISAFLSSIMNNMPTVLIDAIAIGQSNVHGMLKEGLIYANVIGSDLGPKITPIGSLATLLWLHVLTQKDVKIS
WGTYFKTGIIFTIPVLFITLIGLYLTLIIF
>Mature_430_residues
MMTTLATLIFLVTLLFVLWQPKGLDIGITALTGAFIAIITGVVSFSDVFEVTGIVWNATLTFVSVILISLILDKVGLFEW
SAIHMLHASKGNGLKMFVYIILLCAIVAAFFANDGAALILTPIVLAMVKNIGFNKRAIFPFIIASGFIADTTSLPLIVSN
LVNIISAYYFHVGFVRYFSRMFIPNLFSLLASIIVLWLYFRKAIPKTFDDNNIKRPKDAINDLKLFKISWIVLVILLFGY
LISEFTKIPVSIFTGIIAFIFLMLARKSNAVNIKEVIKGAPWNIVLFSIGMYIVVFGLRNAGITLILAKILEYISNYGLF
STILGMGFISAFLSSIMNNMPTVLIDAIAIGQSNVHGMLKEGLIYANVIGSDLGPKITPIGSLATLLWLHVLTQKDVKIS
WGTYFKTGIIFTIPVLFITLIGLYLTLIIF

Specific function: Involved in arsenical resistance. Thought to form the channel of an arsenite pump [H]

COG id: COG1055

COG function: function code P; Na+/H+ antiporter NhaD and related arsenite permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsB family [H]

Homologues:

Organism=Escherichia coli, GI87082277, Length=423, Percent_Identity=54.8463356973995, Blast_Score=448, Evalue=1e-127,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000802 [H]

Pfam domain/function: PF02040 ArsB [H]

EC number: NA

Molecular weight: Translated: 47496; Mature: 47496

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHC
>Mature Secondary Structure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HHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; arsenite [Cytoplasm]; H2O [C]

Specific reaction: ATP + arsenite [Cytoplasm] + H2O = ADP + phosphate + arsenite [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA