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The map label for this gene is trpF

Identifier: 82750962

GI number: 82750962

Start: 1341958

End: 1342590

Strand: Direct

Name: trpF

Synonym: SAB1226

Alternate gene names: 82750962

Gene position: 1341958-1342590 (Clockwise)

Preceding gene: 82750961

Following gene: 82750963

Centisome position: 48.93

GC content: 32.07

Gene sequence:

>633_bases
ATGAAATTGAAATTTTGTGGCTTTACATCAATCGAGGATGTTACAGCGGCCAGTCAATTACCTATTGATGCGATAGGTTT
CATTCATTATGAAAAAAGTAAAAGTCATCAAACAATTACCCAAATAAAAAAGTTAGCGTCTGCTGTTCCAGAACATATTG
ACAAAGTATGTGTCGTGGTAAATCCTGATTTAACAACTATTGAACACGTATTAAGCAATACGCCAATTAACACAATACAG
TTACACGGCACAGAATCTATTGATTTTATACAGGAAATTAAAAAGAAGTATTCAAGCATTAAGATTACTAAAGCTTTAGC
TGCAGATGAAAACATAATCCAAAACATAAATAAATATAAAGGTTTCGTAGATTTATTTATTATCGACACACCCTCAGTGT
CGTATGGTGGTACCGGTCAAACATATGACTGGACTATTTTGAAGCACATAAAAGACATACCTTACTTGATAGCAGGAGGC
ATTAACTCTGAAAATATACAAACAGTTAATCAACTTAAATTATCACATCAAGGTTTTGATCTTGCATCAGGTATAGAAGT
AAATGGGCGAAAAGATATAGAAAAAATGACAGCAATTGTAAATATTGTGAAAGGAGATAGAGAAAATGAATAA

Upstream 100 bases:

>100_bases
ATAGTGGTATCGATGGCTTACTAATAGGTGAGGCGCTTATGCGTTGTGACAATCTATCTGAATTTTTACCACAACTAAAA
ATGCAAAAGGTGAAGTCATG

Downstream 100 bases:

>100_bases
ACAAATACAAACAGAAGCAGATGAATTAGGTTTCTTTGGTGAATATGGAGGGCAATATGTTCCAGAAACATTAATGCCAG
CAATTATTGAGTTGAAAAAA

Product: N-(5'-phosphoribosyl)anthranilate isomerase

Products: NA

Alternate protein names: PRAI [H]

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MKLKFCGFTSIEDVTAASQLPIDAIGFIHYEKSKSHQTITQIKKLASAVPEHIDKVCVVVNPDLTTIEHVLSNTPINTIQ
LHGTESIDFIQEIKKKYSSIKITKALAADENIIQNINKYKGFVDLFIIDTPSVSYGGTGQTYDWTILKHIKDIPYLIAGG
INSENIQTVNQLKLSHQGFDLASGIEVNGRKDIEKMTAIVNIVKGDRENE

Sequences:

>Translated_210_residues
MKLKFCGFTSIEDVTAASQLPIDAIGFIHYEKSKSHQTITQIKKLASAVPEHIDKVCVVVNPDLTTIEHVLSNTPINTIQ
LHGTESIDFIQEIKKKYSSIKITKALAADENIIQNINKYKGFVDLFIIDTPSVSYGGTGQTYDWTILKHIKDIPYLIAGG
INSENIQTVNQLKLSHQGFDLASGIEVNGRKDIEKMTAIVNIVKGDRENE
>Mature_210_residues
MKLKFCGFTSIEDVTAASQLPIDAIGFIHYEKSKSHQTITQIKKLASAVPEHIDKVCVVVNPDLTTIEHVLSNTPINTIQ
LHGTESIDFIQEIKKKYSSIKITKALAADENIIQNINKYKGFVDLFIIDTPSVSYGGTGQTYDWTILKHIKDIPYLIAGG
INSENIQTVNQLKLSHQGFDLASGIEVNGRKDIEKMTAIVNIVKGDRENE

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00697 PRAI [H]

EC number: =5.3.1.24 [H]

Molecular weight: Translated: 23312; Mature: 23312

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKFCGFTSIEDVTAASQLPIDAIGFIHYEKSKSHQTITQIKKLASAVPEHIDKVCVVV
CEEEECCCCCHHHHHHHHCCCCHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEEE
NPDLTTIEHVLSNTPINTIQLHGTESIDFIQEIKKKYSSIKITKALAADENIIQNINKYK
CCCHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
GFVDLFIIDTPSVSYGGTGQTYDWTILKHIKDIPYLIAGGINSENIQTVNQLKLSHQGFD
CEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHCCCCC
LASGIEVNGRKDIEKMTAIVNIVKGDRENE
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKLKFCGFTSIEDVTAASQLPIDAIGFIHYEKSKSHQTITQIKKLASAVPEHIDKVCVVV
CEEEECCCCCHHHHHHHHCCCCHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEEE
NPDLTTIEHVLSNTPINTIQLHGTESIDFIQEIKKKYSSIKITKALAADENIIQNINKYK
CCCHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
GFVDLFIIDTPSVSYGGTGQTYDWTILKHIKDIPYLIAGGINSENIQTVNQLKLSHQGFD
CEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHCCCCC
LASGIEVNGRKDIEKMTAIVNIVKGDRENE
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA