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The map label for this gene is trpD

Identifier: 82750960

GI number: 82750960

Start: 1340167

End: 1341174

Strand: Direct

Name: trpD

Synonym: SAB1224

Alternate gene names: 82750960

Gene position: 1340167-1341174 (Clockwise)

Preceding gene: 82750959

Following gene: 82750961

Centisome position: 48.87

GC content: 33.93

Gene sequence:

>1008_bases
ATGAAAACCATGACATTACTAACAAGAATAAAAACTGAAACTATATTACTTGAAAGCGACATTAAAGAGCTAATCGAAAT
ACTTATTTCTCCTAGTATTGGAACTGATATTAAATATGAATTACTTAGTTCCTATTCGGAGCGAGAAATCCAACAACAAG
AATTGACATATATTGTACGTAGTTTAATTAATACAATGTACCCACATCAACCATGTTATGAAGGGGCTATGTGTGTGTGC
GGCACAGGTGGTGACAAGTCAAATAGTTTCAACATTTCAACAACTGTAGCTTTTGTCGTAGCAAGTGCTGGTGTTAAAGT
CATTAAACATGGTAATAAAAGCATTACCTCAAATTCAGGTAGTACGGATTTGTTAAATCAAATGAAGATACAAACAACAA
CTGTTGATGATACACCTAACCAATTAAATGAAAAAGACCTTGTATTCATTGGTGCAACTGAATCATATCCAATCATGAAG
TATATGCAACCAGTTAGAAAAATGATTGGAAAGCCTACAATATTAAACCTTGTGGGTCCATTAATTAATCCATATCACTT
AACGTATCAAATGGTAGGCGTCTTTGATCCTACAAAGTTAAAGTTAGTTGCTAAAACGATTAAAGATTTAGGCAGAAAAC
GTGCAATCGTTTTACATGGTGCAAATGGTATGGATGAAGCAACACTATCTGGTGATAATTTGATATATGAATTGACTGAA
GATGGAGAAATCAAAAATTACACATTAAATGCGACTGATTATGGTTTGAAACATGCGCCGAATAGCGATTTTAAAGGTGG
TTCACCTGAAGAAAATTTAACAATCTCCCTTAATATCTTGAATGGTAAAGATCAGTCAAGTCGACGTGATGTGGTTGTCT
TAAATGCAGGTTTAAGCCTTTATGTTGCAGAGAAAGTGGATACCATCGCAGAAGGCATAGAACTTGCAACTACATTGATT
GATAATGGTGAAGCATTGAAAAAATATTATCGAATGAGAGGTGAATAA

Upstream 100 bases:

>100_bases
AAGAAAGACCGCATTATGGTATTCAGTACCATCCTGAATCATTTGCTACAGACTATGGTGTCAAAATAATTACTAATTTT
ATTAATCTAGTGAAGAAAGG

Downstream 100 bases:

>100_bases
TATGACGATTTTAGCAGAAATTGTTAAATATAAACAGTCACTTTTACAAAATGGGTATTATCAAGACAAACTTAATACCT
TGAAAAGTGTGAAGATTCAG

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKTMTLLTRIKTETILLESDIKELIEILISPSIGTDIKYELLSSYSEREIQQQELTYIVRSLINTMYPHQPCYEGAMCVC
GTGGDKSNSFNISTTVAFVVASAGVKVIKHGNKSITSNSGSTDLLNQMKIQTTTVDDTPNQLNEKDLVFIGATESYPIMK
YMQPVRKMIGKPTILNLVGPLINPYHLTYQMVGVFDPTKLKLVAKTIKDLGRKRAIVLHGANGMDEATLSGDNLIYELTE
DGEIKNYTLNATDYGLKHAPNSDFKGGSPEENLTISLNILNGKDQSSRRDVVVLNAGLSLYVAEKVDTIAEGIELATTLI
DNGEALKKYYRMRGE

Sequences:

>Translated_335_residues
MKTMTLLTRIKTETILLESDIKELIEILISPSIGTDIKYELLSSYSEREIQQQELTYIVRSLINTMYPHQPCYEGAMCVC
GTGGDKSNSFNISTTVAFVVASAGVKVIKHGNKSITSNSGSTDLLNQMKIQTTTVDDTPNQLNEKDLVFIGATESYPIMK
YMQPVRKMIGKPTILNLVGPLINPYHLTYQMVGVFDPTKLKLVAKTIKDLGRKRAIVLHGANGMDEATLSGDNLIYELTE
DGEIKNYTLNATDYGLKHAPNSDFKGGSPEENLTISLNILNGKDQSSRRDVVVLNAGLSLYVAEKVDTIAEGIELATTLI
DNGEALKKYYRMRGE
>Mature_335_residues
MKTMTLLTRIKTETILLESDIKELIEILISPSIGTDIKYELLSSYSEREIQQQELTYIVRSLINTMYPHQPCYEGAMCVC
GTGGDKSNSFNISTTVAFVVASAGVKVIKHGNKSITSNSGSTDLLNQMKIQTTTVDDTPNQLNEKDLVFIGATESYPIMK
YMQPVRKMIGKPTILNLVGPLINPYHLTYQMVGVFDPTKLKLVAKTIKDLGRKRAIVLHGANGMDEATLSGDNLIYELTE
DGEIKNYTLNATDYGLKHAPNSDFKGGSPEENLTISLNILNGKDQSSRRDVVVLNAGLSLYVAEKVDTIAEGIELATTLI
DNGEALKKYYRMRGE

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=206, Percent_Identity=42.7184466019417, Blast_Score=153, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6320561, Length=266, Percent_Identity=29.3233082706767, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312 [H]

Pfam domain/function: PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 36985; Mature: 36985

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTMTLLTRIKTETILLESDIKELIEILISPSIGTDIKYELLSSYSEREIQQQELTYIVR
CCHHHHHHHHHHHEEEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SLINTMYPHQPCYEGAMCVCGTGGDKSNSFNISTTVAFVVASAGVKVIKHGNKSITSNSG
HHHHHHCCCCCCCCCCEEEEECCCCCCCCEEHHHHHHHHHHHCCEEEEECCCCCCCCCCC
STDLLNQMKIQTTTVDDTPNQLNEKDLVFIGATESYPIMKYMQPVRKMIGKPTILNLVGP
CHHHHHHEEEEEEECCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHH
LINPYHLTYQMVGVFDPTKLKLVAKTIKDLGRKRAIVLHGANGMDEATLSGDNLIYELTE
HCCCEEEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEECCCCEEEEECC
DGEIKNYTLNATDYGLKHAPNSDFKGGSPEENLTISLNILNGKDQSSRRDVVVLNAGLSL
CCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEECCCEE
YVAEKVDTIAEGIELATTLIDNGEALKKYYRMRGE
EEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure
MKTMTLLTRIKTETILLESDIKELIEILISPSIGTDIKYELLSSYSEREIQQQELTYIVR
CCHHHHHHHHHHHEEEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SLINTMYPHQPCYEGAMCVCGTGGDKSNSFNISTTVAFVVASAGVKVIKHGNKSITSNSG
HHHHHHCCCCCCCCCCEEEEECCCCCCCCEEHHHHHHHHHHHCCEEEEECCCCCCCCCCC
STDLLNQMKIQTTTVDDTPNQLNEKDLVFIGATESYPIMKYMQPVRKMIGKPTILNLVGP
CHHHHHHEEEEEEECCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHH
LINPYHLTYQMVGVFDPTKLKLVAKTIKDLGRKRAIVLHGANGMDEATLSGDNLIYELTE
HCCCEEEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEECCCCEEEEECC
DGEIKNYTLNATDYGLKHAPNSDFKGGSPEENLTISLNILNGKDQSSRRDVVVLNAGLSL
CCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEECCCEE
YVAEKVDTIAEGIELATTLIDNGEALKKYYRMRGE
EEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA