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The map label for this gene is msrA1

Identifier: 82750953

GI number: 82750953

Start: 1331972

End: 1332481

Strand: Reverse

Name: msrA1

Synonym: SAB1217c

Alternate gene names: 82750953

Gene position: 1332481-1331972 (Counterclockwise)

Preceding gene: 82750956

Following gene: 82750946

Centisome position: 48.59

GC content: 33.73

Gene sequence:

>510_bases
ATGAATATTAATACAGCTTATTTTGCCGGAGGTTGTTTTTGGTGTATGACGAAACCATTTGACACCTTTGACGGCATAGA
AAAAGTAACTTCTGGATATATGGGCGGACATATTGAAAATCCTACTTACGAACAAGTAAAATCAGGTACGAGTGGTCATT
TAGAAACTGTTGAAATTCAATATGATGTTGCATTATTCTCATACAATAAGTTATTAGAAATATTTTTCTCAGTCATTGAC
CCATTAGATACAGGTGGTCAATATCAAGACCGTGGTCCTCAATATCAAACAGCTATTTTCTACACTAATGATCATCAAAA
AGAACTCGCTGAGACTTATATCGAGCAGCTTAAAAATACGATTAATGCTGATAAGGCAATTGCAACAAAAATATTACCCG
CGTCACAATTTTACAAAGCCGAAGACTATCACCAAGATTTTTATAAGAAAAATCCAGAGCGCTATGCAGAAGAACAAAAA
ATACGCCAAGAATACAAAAATAATCAATAA

Upstream 100 bases:

>100_bases
TGTACTATAATAATCACATATTAACGTTATATAAAAACAATTCAAAAAGCAAGTGATTTCTTAATAAATCGTACTAAGGT
CTAATGAAAGGATGTCAAAA

Downstream 100 bases:

>100_bases
CATTTATACTTGATGAAACTGATTGAACTGATAATAAAAGTTAGGCGACTTAACTTAAGCTCATTTCAATATTAAAATAC
GGTACAGATAGGAAACTTAA

Product: methionine sulfoxide reductase A

Products: NA

Alternate protein names: Protein-methionine-S-oxide reductase 1; Peptide-methionine (S)-S-oxide reductase 1; Peptide Met(O) reductase 1 [H]

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MNINTAYFAGGCFWCMTKPFDTFDGIEKVTSGYMGGHIENPTYEQVKSGTSGHLETVEIQYDVALFSYNKLLEIFFSVID
PLDTGGQYQDRGPQYQTAIFYTNDHQKELAETYIEQLKNTINADKAIATKILPASQFYKAEDYHQDFYKKNPERYAEEQK
IRQEYKNNQ

Sequences:

>Translated_169_residues
MNINTAYFAGGCFWCMTKPFDTFDGIEKVTSGYMGGHIENPTYEQVKSGTSGHLETVEIQYDVALFSYNKLLEIFFSVID
PLDTGGQYQDRGPQYQTAIFYTNDHQKELAETYIEQLKNTINADKAIATKILPASQFYKAEDYHQDFYKKNPERYAEEQK
IRQEYKNNQ
>Mature_169_residues
MNINTAYFAGGCFWCMTKPFDTFDGIEKVTSGYMGGHIENPTYEQVKSGTSGHLETVEIQYDVALFSYNKLLEIFFSVID
PLDTGGQYQDRGPQYQTAIFYTNDHQKELAETYIEQLKNTINADKAIATKILPASQFYKAEDYHQDFYKKNPERYAEEQK
IRQEYKNNQ

Specific function: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine [H]

COG id: COG0225

COG function: function code O; Peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrA Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI6912516, Length=153, Percent_Identity=35.9477124183007, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI208609995, Length=153, Percent_Identity=35.9477124183007, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI208609993, Length=151, Percent_Identity=31.1258278145695, Blast_Score=65, Evalue=3e-11,
Organism=Escherichia coli, GI1790665, Length=153, Percent_Identity=39.2156862745098, Blast_Score=114, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17533973, Length=146, Percent_Identity=36.986301369863, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6320881, Length=158, Percent_Identity=32.2784810126582, Blast_Score=74, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24664627, Length=149, Percent_Identity=30.8724832214765, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45553131, Length=143, Percent_Identity=30.0699300699301, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24664631, Length=149, Percent_Identity=30.2013422818792, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002569 [H]

Pfam domain/function: PF01625 PMSR [H]

EC number: =1.8.4.11 [H]

Molecular weight: Translated: 19597; Mature: 19597

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNINTAYFAGGCFWCMTKPFDTFDGIEKVTSGYMGGHIENPTYEQVKSGTSGHLETVEIQ
CCCCCEEECCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCEEEEEEE
YDVALFSYNKLLEIFFSVIDPLDTGGQYQDRGPQYQTAIFYTNDHQKELAETYIEQLKNT
EHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHH
INADKAIATKILPASQFYKAEDYHQDFYKKNPERYAEEQKIRQEYKNNQ
HCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNINTAYFAGGCFWCMTKPFDTFDGIEKVTSGYMGGHIENPTYEQVKSGTSGHLETVEIQ
CCCCCEEECCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCEEEEEEE
YDVALFSYNKLLEIFFSVIDPLDTGGQYQDRGPQYQTAIFYTNDHQKELAETYIEQLKNT
EHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHH
INADKAIATKILPASQFYKAEDYHQDFYKKNPERYAEEQKIRQEYKNNQ
HCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA