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The map label for this gene is lspA

Identifier: 82750801

GI number: 82750801

Start: 1143377

End: 1143868

Strand: Direct

Name: lspA

Synonym: SAB1060

Alternate gene names: 82750801

Gene position: 1143377-1143868 (Clockwise)

Preceding gene: 82750800

Following gene: 82750802

Centisome position: 41.69

GC content: 27.03

Gene sequence:

>492_bases
ATGCACAAAAAATATTTTATTGGCACTTCCATTTTAATAGCAGTATTTGTCGTTATATTTGACCAAGTTACTAAATATAT
TATAGCTACTACAATGAAAATTGGAGATTCATTTGAAGTGATACCGCACTTTTTAAACATAACATCACATCGAAATAATG
GTGCTGCATGGGGAATATTGAGTGGAAAAATGACATTTTTCTTTATTATTACCATTATTATATTAATAGCCTTAGTATAT
TTCTTTATTAATGATGCTCAATATAATTTGTTTATGCAAGTTGCTATTAGTTTACTTTTTGCAGGTGCACTTGGAAACTT
TATTGATAGAGTTTTAACAGGAGAAGTTGTTGACTTTATTGATACAAATATTTTTGGTTATGATTTTCCAATATTTAATA
TCGCAGATTCAAGTTTAACAATTGGTGTAATATTAATTATTATTGCCTTATTAAAGGATACTTCCAATAAAAAGGAGAAG
GAGGTTAAGTAA

Upstream 100 bases:

>100_bases
GTAACATTAGATTTAATGTAATATGCTTACTTTTTTTATTAGCAGGTGTAAGCTATAATATAAAGAGTTGTCTTATGGAC
GATTGATTGGAGGAACGAAA

Downstream 100 bases:

>100_bases
TGGAGACTTATGAATTTAACATTACAGATAAAGAACAAACAGGTATGCGTGTAGATAAGTTGCTGCCTGAATTAAATAGT
GATTGGTCTCGTAACCAGAT

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MHKKYFIGTSILIAVFVVIFDQVTKYIIATTMKIGDSFEVIPHFLNITSHRNNGAAWGILSGKMTFFFIITIIILIALVY
FFINDAQYNLFMQVAISLLFAGALGNFIDRVLTGEVVDFIDTNIFGYDFPIFNIADSSLTIGVILIIIALLKDTSNKKEK
EVK

Sequences:

>Translated_163_residues
MHKKYFIGTSILIAVFVVIFDQVTKYIIATTMKIGDSFEVIPHFLNITSHRNNGAAWGILSGKMTFFFIITIIILIALVY
FFINDAQYNLFMQVAISLLFAGALGNFIDRVLTGEVVDFIDTNIFGYDFPIFNIADSSLTIGVILIIIALLKDTSNKKEK
EVK
>Mature_163_residues
MHKKYFIGTSILIAVFVVIFDQVTKYIIATTMKIGDSFEVIPHFLNITSHRNNGAAWGILSGKMTFFFIITIIILIALVY
FFINDAQYNLFMQVAISLLFAGALGNFIDRVLTGEVVDFIDTNIFGYDFPIFNIADSSLTIGVILIIIALLKDTSNKKEK
EVK

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=153, Percent_Identity=32.6797385620915, Blast_Score=73, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 18314; Mature: 18314

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKKYFIGTSILIAVFVVIFDQVTKYIIATTMKIGDSFEVIPHFLNITSHRNNGAAWGIL
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEE
SGKMTFFFIITIIILIALVYFFINDAQYNLFMQVAISLLFAGALGNFIDRVLTGEVVDFI
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DTNIFGYDFPIFNIADSSLTIGVILIIIALLKDTSNKKEKEVK
HCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MHKKYFIGTSILIAVFVVIFDQVTKYIIATTMKIGDSFEVIPHFLNITSHRNNGAAWGIL
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEE
SGKMTFFFIITIIILIALVYFFINDAQYNLFMQVAISLLFAGALGNFIDRVLTGEVVDFI
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DTNIFGYDFPIFNIADSSLTIGVILIIIALLKDTSNKKEKEVK
HCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA