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The map label for this gene is scn [H]

Identifier: 82750765

GI number: 82750765

Start: 1105122

End: 1105472

Strand: Direct

Name: scn [H]

Synonym: SAB1022

Alternate gene names: 82750765

Gene position: 1105122-1105472 (Clockwise)

Preceding gene: 82750764

Following gene: 82750771

Centisome position: 40.3

GC content: 29.06

Gene sequence:

>351_bases
ATGAAATTTAAAAAATATATATTAACAGGAACATTAGCATTACTTTTATCATCAACTGCGATAGCAACTATAGAAGGGAA
TAAAGCAGATGCAAGTAGTCTGGACAAATATTTAACTGAAAGTCAGTTTCATGATAAACGCATAGCAGAAGAATTAAGAA
CTTTACTTAATAAATCGAATGTATATGCATTAGCTGCAGGCAGCTTAAATCCATATTATAAACGTACGATTATGATGAAT
GAATATAGAGCTAAAGCGGCACTTAGGAGTAATAACTTCGCTAAAATGGCTGATGCTAAAGTTGCATTAGAAAAAATATA
CAAAGAAATTAATGAAATTATAAATAGATAA

Upstream 100 bases:

>100_bases
TTATTAATGAAAAAAAGTAATCTATTTAATGACAGGTTAATGTAATTGTCATGAAATTGACTATATACTCAGTAAGTATC
AATTTTAAGGAAAGTTTACA

Downstream 100 bases:

>100_bases
TAAATAAAACAGGTTGAGACAAAAAATGGTCTTAACCTGTTTTCAATTAGCAAATGTGATAAATTCTATATCAAATTACT
TATGTATAATGAATGACATT

Product: fibrinogen-binding protein precursor

Products: NA

Alternate protein names: SCIN [H]

Number of amino acids: Translated: 116; Mature: 116

Protein sequence:

>116_residues
MKFKKYILTGTLALLLSSTAIATIEGNKADASSLDKYLTESQFHDKRIAEELRTLLNKSNVYALAAGSLNPYYKRTIMMN
EYRAKAALRSNNFAKMADAKVALEKIYKEINEIINR

Sequences:

>Translated_116_residues
MKFKKYILTGTLALLLSSTAIATIEGNKADASSLDKYLTESQFHDKRIAEELRTLLNKSNVYALAAGSLNPYYKRTIMMN
EYRAKAALRSNNFAKMADAKVALEKIYKEINEIINR
>Mature_116_residues
MKFKKYILTGTLALLLSSTAIATIEGNKADASSLDKYLTESQFHDKRIAEELRTLLNKSNVYALAAGSLNPYYKRTIMMN
EYRAKAALRSNNFAKMADAKVALEKIYKEINEIINR

Specific function: Involved in countering the first line of host defense mechanisms. Efficiently inhibits opsonization, phagocytosis and killing of S.aureus by human neutrophils. Acts by binding and stabilizing human C3 convertases (C4b2a and C3bBb), leading to their inacti

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SCIN family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021612 [H]

Pfam domain/function: PF11546 CompInhib_SCIN [H]

EC number: NA

Molecular weight: Translated: 13126; Mature: 13126

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFKKYILTGTLALLLSSTAIATIEGNKADASSLDKYLTESQFHDKRIAEELRTLLNKSN
CCHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VYALAAGSLNPYYKRTIMMNEYRAKAALRSNNFAKMADAKVALEKIYKEINEIINR
EEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFKKYILTGTLALLLSSTAIATIEGNKADASSLDKYLTESQFHDKRIAEELRTLLNKSN
CCHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VYALAAGSLNPYYKRTIMMNEYRAKAALRSNNFAKMADAKVALEKIYKEINEIINR
EEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA