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The map label for this gene is ctaB

Identifier: 82750724

GI number: 82750724

Start: 1065050

End: 1065961

Strand: Direct

Name: ctaB

Synonym: SAB0981

Alternate gene names: 82750724

Gene position: 1065050-1065961 (Clockwise)

Preceding gene: 82750722

Following gene: 82750725

Centisome position: 38.83

GC content: 32.24

Gene sequence:

>912_bases
ATGAGCAAAGAGCATACTTTGTCACAAAATATTAGCAGAGTTAACTTCAAAGAATTGCAACAGATAATTAAAATGGGACT
TGTTCAAGGTAACTTAATTCCGGCTTTTGCGGGCGCATGGCTAGCAGTTGTAATGACAAATCATTCCTTCTTATCATCAA
TACCTCAAATTTTATTAATGCTATTAGGATCTACTTTAATTATGGGTGGCGCATGTGCGTTAAATAATTATTACGACCAA
GATATTGATCGTATTATGCCTAGTAAACAAAATAGACCAACTGTAAATAATAGAATTACAGATCAAAATTTATTATTATT
AAGTTTTGGTATGATGTTAGTTGGAGAAATTTGTTTGTTTTTATTGAATATACCATCAGGCGTACTTGGTCTTATGGGGA
TTGTAGGTTATGTGTCTTATTACTCAATATGGTCTAAAAGACATACAACATGGAACACAGTGATTGGGAGTTTTCCTGGA
GCAGTACCACCACTAATTGGGTGGGTTGCAATTGAAGGACAAATTAGTTTAACAGCGATTGCGCTGTTTTTAGTTGTATT
TTGTTGGCAACCAATTCATTTTTATGCCTTAGCTATTAAACGTAAAGATGAATATGCACTTGCAAATATTCCAATGTTAC
CATCAGTTAAGGGCTTTAAACGTACACGTGTCAGTATGTTTATCTGGTTGATTATTTTATTGCCAGTACCTTTATTACTA
ATAAATTTAGGTGTCGTATTCGTAGTGTTAGCTACATTATTAAATTTAGGATGGATTGCATTAGGTTTAACAACATTTAA
GAAAAATTCAGATCAAACAAAATGGGCAACACAAATGTTTATATATTCACTAAATTATTTAGTGATCTTTTTCGTGTTAG
CTGTGATTGTTTCATTACTTACTTTGATCTAG

Upstream 100 bases:

>100_bases
CTTGTCGTTAATTTGTCACAATTTAATTTTATTAAACCTAGTCTTTTTATGCAATCTAAGATATCATAATCTTATATGAA
CAAATTTAAGGAGGGGGATT

Downstream 100 bases:

>100_bases
ATTAATTAAGTTAGGATGAAAAATATGGGCGTTCCAATTTTACCAACGATTAGTACGACATGTATTGTCATTAGTGCAAT
TTTAATTGCCATTGGTTGGA

Product: protoheme IX farnesyltransferase

Products: NA

Alternate protein names: Heme B farnesyltransferase; Heme O synthase [H]

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MSKEHTLSQNISRVNFKELQQIIKMGLVQGNLIPAFAGAWLAVVMTNHSFLSSIPQILLMLLGSTLIMGGACALNNYYDQ
DIDRIMPSKQNRPTVNNRITDQNLLLLSFGMMLVGEICLFLLNIPSGVLGLMGIVGYVSYYSIWSKRHTTWNTVIGSFPG
AVPPLIGWVAIEGQISLTAIALFLVVFCWQPIHFYALAIKRKDEYALANIPMLPSVKGFKRTRVSMFIWLIILLPVPLLL
INLGVVFVVLATLLNLGWIALGLTTFKKNSDQTKWATQMFIYSLNYLVIFFVLAVIVSLLTLI

Sequences:

>Translated_303_residues
MSKEHTLSQNISRVNFKELQQIIKMGLVQGNLIPAFAGAWLAVVMTNHSFLSSIPQILLMLLGSTLIMGGACALNNYYDQ
DIDRIMPSKQNRPTVNNRITDQNLLLLSFGMMLVGEICLFLLNIPSGVLGLMGIVGYVSYYSIWSKRHTTWNTVIGSFPG
AVPPLIGWVAIEGQISLTAIALFLVVFCWQPIHFYALAIKRKDEYALANIPMLPSVKGFKRTRVSMFIWLIILLPVPLLL
INLGVVFVVLATLLNLGWIALGLTTFKKNSDQTKWATQMFIYSLNYLVIFFVLAVIVSLLTLI
>Mature_302_residues
SKEHTLSQNISRVNFKELQQIIKMGLVQGNLIPAFAGAWLAVVMTNHSFLSSIPQILLMLLGSTLIMGGACALNNYYDQD
IDRIMPSKQNRPTVNNRITDQNLLLLSFGMMLVGEICLFLLNIPSGVLGLMGIVGYVSYYSIWSKRHTTWNTVIGSFPGA
VPPLIGWVAIEGQISLTAIALFLVVFCWQPIHFYALAIKRKDEYALANIPMLPSVKGFKRTRVSMFIWLIILLPVPLLLI
NLGVVFVVLATLLNLGWIALGLTTFKKNSDQTKWATQMFIYSLNYLVIFFVLAVIVSLLTLI

Specific function: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group [H]

COG id: COG0109

COG function: function code O; Polyprenyltransferase (cytochrome oxidase assembly factor)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI17921982, Length=162, Percent_Identity=30.8641975308642, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1786631, Length=274, Percent_Identity=34.6715328467153, Blast_Score=148, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6325085, Length=188, Percent_Identity=28.7234042553192, Blast_Score=69, Evalue=8e-13,
Organism=Drosophila melanogaster, GI19921064, Length=234, Percent_Identity=26.0683760683761, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006369
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 33825; Mature: 33694

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKEHTLSQNISRVNFKELQQIIKMGLVQGNLIPAFAGAWLAVVMTNHSFLSSIPQILLM
CCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LLGSTLIMGGACALNNYYDQDIDRIMPSKQNRPTVNNRITDQNLLLLSFGMMLVGEICLF
HHHHHHHHCCHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LLNIPSGVLGLMGIVGYVSYYSIWSKRHTTWNTVIGSFPGAVPPLIGWVAIEGQISLTAI
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHEECCCHHHHHH
ALFLVVFCWQPIHFYALAIKRKDEYALANIPMLPSVKGFKRTRVSMFIWLIILLPVPLLL
HHHHHHHHHHHHHHHHHHHHCCCCHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
INLGVVFVVLATLLNLGWIALGLTTFKKNSDQTKWATQMFIYSLNYLVIFFVLAVIVSLL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLI
HHC
>Mature Secondary Structure 
SKEHTLSQNISRVNFKELQQIIKMGLVQGNLIPAFAGAWLAVVMTNHSFLSSIPQILLM
CCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH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HHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA