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The map label for this gene is pyc [H]

Identifier: 82750722

GI number: 82750722

Start: 1060107

End: 1063559

Strand: Direct

Name: pyc [H]

Synonym: SAB0979

Alternate gene names: 82750722

Gene position: 1060107-1063559 (Clockwise)

Preceding gene: 82750721

Following gene: 82750724

Centisome position: 38.65

GC content: 35.42

Gene sequence:

>3453_bases
TTGAAACAAATAAAAAAGTTACTTGTTGCTAACCGTGGAGAAATTGCAATTCGTATATTCAGAGCGGCAGCAGAATTAGA
CATCAGCACAGTTGCAATTTATTCGAATGAAGACAAAAGTTCATTACATAGATATAAAGCAGATGAATCCTATTTAGTTG
GAAGTGATTTAGGTCCTGCTGAAAGTTATTTAAATATTGAGCGTATCATTGATGTAGCAAAACAAGCGAATGTGGATGCG
ATTCATCCTGGCTATGGATTTTTAAGTGAAAATGAACAATTTGCGCGTCGTTGTGCAGAAGAAGGGATTAAATTTATTGG
TCCTCATTTAGAACATTTAGATATGTTTGGAGATAAAGTTAAAGCTCGTACAACGGCTATCAAGGCAGATTTACCAGTTA
TTCCTGGTACAGAGGGTCCAATTAAATCATATGAATTAGCAAAAGAATTTGCAGAAGAAGCTGGTTTCCCGCTAATGATT
AAAGCCACAAGTGGTGGCGGCGGTAAAGGTATGAGAATCGTTCGTGAAGAAAGTGAATTAGAAGATGCTTTCCATAGAGC
AAAATCAGAAGCAGAAAAATCATTTGGTAATAGTGAAGTTTACATAGAAAGATACATTGATAATCCAAAGCATATTGAAG
TACAAGTCATAGGTGACGAACATGGAAATATCGTACACTTATTTGAACGTGATTGTTCAGTACAACGTCGTCATCAAAAA
GTTGTAGAAGTTGCACCATCAGTTGGATTATCACCAACATTACGTCAACGTATTTGTGATGCTGCAATTCAATTGATGGA
AAATATTAAATATGTCAATGCAGGTACTGTTGAGTTTCTAGTATCTGGTGACGAATTCTTCTTTATAGAAGTTAACCCTC
GTGTACAAGTAGAGCATACAATTACAGAGATGGTAACAGGAATTGATATTGTTAAGACACAAATTTTAGTTGCAGCAGGT
GCCGATTTATTTGGTGAAGAGATTAATATGCCGCAACAAAAAGATATTACAACATTGGGCTATGCCATCCAATGTCGTAT
TACAACAGAAGCTCCGTTAAATGATTTCATGCCGGATACTGGAACAATCATTGCTTATCGTTCAAGCGGTGGCTTTGGTG
TACGTCTTGATGCTGGAGATGGTTTCCAAGGTGCTGAGATATCACCTTATTATGATTCATTACTCGTAAAATTATCTACA
CATGCGATATCATTTAAACAAGCAGAAGAAAAAATGGTACGTTCATTACGAGAAATGCGTATTCGTGGTGTTAAAACTAA
TATTCCATTCTTAATTAATGTAATGAAGAATAAAAAGTTCACAAGTGGTGATTACACAACTAAATTTATTGAAGAAACAC
CAGAACTTTTCGACATTCAGCCGTCTCTAGATAGAGGTACTAAAACATTAGAATATATAGGTAATGTAACAATTAATGGT
TTCCCAAATGTTGAGAAACGTCCGAAACCAGACTATGAATTAGCATCAATTCCAACTGTATCTTCAAGTAAAATCGCTTC
ATTTAGTGGTACGAAACAATTGCTTGATGAAGTAGGTCCAAAAGGTGTAGCTGAATGGGTTAAAAAGCAGGATGATGTCT
TACTAACAGATACAACCTTTAGAGATGCACACCAATCATTATTAGCTACACGAGTTAGAACTAAGGATATGATTAATATC
GCATCCAAAACAGCGGACGTATTTAAAGACGGTTTCTCACTAGAAATGTGGGGCGGTGCTACATTTGATGTGGCATATAA
TTTCTTGAAGGAAAACCCATGGGAACGACTTGAACGTCTACGTAAAGCTATTCCAAATGTATTATTCCAAATGTTGTTAC
GTGCTTCAAACGCAGTTGGTTATAAAAACTATCCTGATAATGTTATTCATAAATTCGTACAAGAAAGTGCTAAAGCAGGC
ATAGATGTCTTTAGAATTTTCGATTCATTAAACTGGGTAGATCAAATGAAAGTTGCCAATGAAGCAGTACAAGAAGCGGG
CAAAATCTCAGAAGGTACTATTTGTTATACAGGTGACATTTTAAATCCTGAGCGATCAAACATTTATACTTTAGAGTATT
ATGTCAAACTAGCTAAAGAGTTAGAACGTGAAGGTTTCCATATTTTAGCGATTAAAGATATGGCAGGCTTATTAAAACCT
AAAGCTGCTTACGAATTGATTGGTGAGTTAAAAGCAGCAGTAGATTTACCAATCCATCTTCACACTCATGATACAAGTGG
TAATGGTTTATTAACGTACAAACAAGCAATAGATGCTGGTGTCGATATCATTGATACTGCTGTTGCTTCAATGAGTGGTT
TAACAAGTCAGCCAAGCGCCAATTCGTTATATTATGCATTAAATGGCTTCCCACGTCACCTTAGAACTGATATTGAAGGT
ATGGAGTCACTTAGTCATTATTGGTCAACTGTACGTACTTATTATTCAGACTTTGAGAGTGATATCAAATCACCGAATAC
TGAAATTTATCAACATGAAATGCCTGGTGGACAGTATTCGAATTTAAGTCAACAAGCTAAAAGTTTAGGTTTAGGCGAAA
GATTTGATGAAGTCAAAGATATGTATCGCAGAGTGAACTTCTTATTTGGTGATATCGTAAAAGTAACTCCATCGTCTAAA
GTAGTTGGTGATATGGCACTTTATATGGTTCAAAATGATCTTGATGAACAATCCGTGATTACAGATGGCTATAAATTAGA
TTTCCCAGAATCAGTAGTGTCGTTCTTCAAAGGTGAAATAGGACAACCTGTAAATGGTTTTAATAAAGATTTACAAGCGG
TTATTTTAAAAGGCCAAGAAGCATTAACAGCTCGTCCAGGTGAATATCTAGAGCCAGTTGATTTTGAAAAAGTCCGTGAG
TTGCTTGAAGAAGAGCAACAAGGTCCTGTTACGGAGCAAGATATTATTAGTTATGTATTATATCCAAAAGTATATGAACA
ATATATTCAAACTAGAAATCAATACGGAAACTTATCGTTACTTGATACGCCTACATTCTTCTTTGGAATGCGTAATGGTG
AAACAGTAGAAATCGAAATCGATAAAGGTAAACGATTAATTATTAAACTAGAAACGATTAGTGAACCAGATGAAAATGGT
AATAGAACGATTTACTATGCGATGAATGGTCAAGCGAGACGTATTTATATTAAAGATGAAAATGTGCATACAAATGCGAA
CGTTAAGCCAAAAGCAGATAAAAGTAATCCAAGTCATATCGGTGCGCAAATGCCAGGTTCAGTAACTGAAGTCAAGGTTA
GTGTAGGTGAAACTGTGAAAGCTAATCAACCGTTGCTAATTACTGAAGCTATGAAAATGGAAACAACAATTCAAGCACCA
TTTGACGGTATGATTAAACAAGTAACTGTAAATAATGGTGACACAATAGCGACAGGTGATTTATTAATCGAAATTGAAAA
AGCAACTGACTAA

Upstream 100 bases:

>100_bases
AAAATTTGAAACATAACTATAGCAAAACAGAGCGCTTTAAGATAAAATTTTATTATCTAATTAGTTAGAAAATTCTAATA
GTTTGAGGAGTGTATCGCTA

Downstream 100 bases:

>100_bases
AATGATTAAAATAAAACGAGATTACACAACAATTGACGTGTAATCTCGTTTTTACTTGTCTTAGGTTTAATTTTAAATAT
TGATATAAAAAACCGTAATT

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1150; Mature: 1150

Protein sequence:

>1150_residues
MKQIKKLLVANRGEIAIRIFRAAAELDISTVAIYSNEDKSSLHRYKADESYLVGSDLGPAESYLNIERIIDVAKQANVDA
IHPGYGFLSENEQFARRCAEEGIKFIGPHLEHLDMFGDKVKARTTAIKADLPVIPGTEGPIKSYELAKEFAEEAGFPLMI
KATSGGGGKGMRIVREESELEDAFHRAKSEAEKSFGNSEVYIERYIDNPKHIEVQVIGDEHGNIVHLFERDCSVQRRHQK
VVEVAPSVGLSPTLRQRICDAAIQLMENIKYVNAGTVEFLVSGDEFFFIEVNPRVQVEHTITEMVTGIDIVKTQILVAAG
ADLFGEEINMPQQKDITTLGYAIQCRITTEAPLNDFMPDTGTIIAYRSSGGFGVRLDAGDGFQGAEISPYYDSLLVKLST
HAISFKQAEEKMVRSLREMRIRGVKTNIPFLINVMKNKKFTSGDYTTKFIEETPELFDIQPSLDRGTKTLEYIGNVTING
FPNVEKRPKPDYELASIPTVSSSKIASFSGTKQLLDEVGPKGVAEWVKKQDDVLLTDTTFRDAHQSLLATRVRTKDMINI
ASKTADVFKDGFSLEMWGGATFDVAYNFLKENPWERLERLRKAIPNVLFQMLLRASNAVGYKNYPDNVIHKFVQESAKAG
IDVFRIFDSLNWVDQMKVANEAVQEAGKISEGTICYTGDILNPERSNIYTLEYYVKLAKELEREGFHILAIKDMAGLLKP
KAAYELIGELKAAVDLPIHLHTHDTSGNGLLTYKQAIDAGVDIIDTAVASMSGLTSQPSANSLYYALNGFPRHLRTDIEG
MESLSHYWSTVRTYYSDFESDIKSPNTEIYQHEMPGGQYSNLSQQAKSLGLGERFDEVKDMYRRVNFLFGDIVKVTPSSK
VVGDMALYMVQNDLDEQSVITDGYKLDFPESVVSFFKGEIGQPVNGFNKDLQAVILKGQEALTARPGEYLEPVDFEKVRE
LLEEEQQGPVTEQDIISYVLYPKVYEQYIQTRNQYGNLSLLDTPTFFFGMRNGETVEIEIDKGKRLIIKLETISEPDENG
NRTIYYAMNGQARRIYIKDENVHTNANVKPKADKSNPSHIGAQMPGSVTEVKVSVGETVKANQPLLITEAMKMETTIQAP
FDGMIKQVTVNNGDTIATGDLLIEIEKATD

Sequences:

>Translated_1150_residues
MKQIKKLLVANRGEIAIRIFRAAAELDISTVAIYSNEDKSSLHRYKADESYLVGSDLGPAESYLNIERIIDVAKQANVDA
IHPGYGFLSENEQFARRCAEEGIKFIGPHLEHLDMFGDKVKARTTAIKADLPVIPGTEGPIKSYELAKEFAEEAGFPLMI
KATSGGGGKGMRIVREESELEDAFHRAKSEAEKSFGNSEVYIERYIDNPKHIEVQVIGDEHGNIVHLFERDCSVQRRHQK
VVEVAPSVGLSPTLRQRICDAAIQLMENIKYVNAGTVEFLVSGDEFFFIEVNPRVQVEHTITEMVTGIDIVKTQILVAAG
ADLFGEEINMPQQKDITTLGYAIQCRITTEAPLNDFMPDTGTIIAYRSSGGFGVRLDAGDGFQGAEISPYYDSLLVKLST
HAISFKQAEEKMVRSLREMRIRGVKTNIPFLINVMKNKKFTSGDYTTKFIEETPELFDIQPSLDRGTKTLEYIGNVTING
FPNVEKRPKPDYELASIPTVSSSKIASFSGTKQLLDEVGPKGVAEWVKKQDDVLLTDTTFRDAHQSLLATRVRTKDMINI
ASKTADVFKDGFSLEMWGGATFDVAYNFLKENPWERLERLRKAIPNVLFQMLLRASNAVGYKNYPDNVIHKFVQESAKAG
IDVFRIFDSLNWVDQMKVANEAVQEAGKISEGTICYTGDILNPERSNIYTLEYYVKLAKELEREGFHILAIKDMAGLLKP
KAAYELIGELKAAVDLPIHLHTHDTSGNGLLTYKQAIDAGVDIIDTAVASMSGLTSQPSANSLYYALNGFPRHLRTDIEG
MESLSHYWSTVRTYYSDFESDIKSPNTEIYQHEMPGGQYSNLSQQAKSLGLGERFDEVKDMYRRVNFLFGDIVKVTPSSK
VVGDMALYMVQNDLDEQSVITDGYKLDFPESVVSFFKGEIGQPVNGFNKDLQAVILKGQEALTARPGEYLEPVDFEKVRE
LLEEEQQGPVTEQDIISYVLYPKVYEQYIQTRNQYGNLSLLDTPTFFFGMRNGETVEIEIDKGKRLIIKLETISEPDENG
NRTIYYAMNGQARRIYIKDENVHTNANVKPKADKSNPSHIGAQMPGSVTEVKVSVGETVKANQPLLITEAMKMETTIQAP
FDGMIKQVTVNNGDTIATGDLLIEIEKATD
>Mature_1150_residues
MKQIKKLLVANRGEIAIRIFRAAAELDISTVAIYSNEDKSSLHRYKADESYLVGSDLGPAESYLNIERIIDVAKQANVDA
IHPGYGFLSENEQFARRCAEEGIKFIGPHLEHLDMFGDKVKARTTAIKADLPVIPGTEGPIKSYELAKEFAEEAGFPLMI
KATSGGGGKGMRIVREESELEDAFHRAKSEAEKSFGNSEVYIERYIDNPKHIEVQVIGDEHGNIVHLFERDCSVQRRHQK
VVEVAPSVGLSPTLRQRICDAAIQLMENIKYVNAGTVEFLVSGDEFFFIEVNPRVQVEHTITEMVTGIDIVKTQILVAAG
ADLFGEEINMPQQKDITTLGYAIQCRITTEAPLNDFMPDTGTIIAYRSSGGFGVRLDAGDGFQGAEISPYYDSLLVKLST
HAISFKQAEEKMVRSLREMRIRGVKTNIPFLINVMKNKKFTSGDYTTKFIEETPELFDIQPSLDRGTKTLEYIGNVTING
FPNVEKRPKPDYELASIPTVSSSKIASFSGTKQLLDEVGPKGVAEWVKKQDDVLLTDTTFRDAHQSLLATRVRTKDMINI
ASKTADVFKDGFSLEMWGGATFDVAYNFLKENPWERLERLRKAIPNVLFQMLLRASNAVGYKNYPDNVIHKFVQESAKAG
IDVFRIFDSLNWVDQMKVANEAVQEAGKISEGTICYTGDILNPERSNIYTLEYYVKLAKELEREGFHILAIKDMAGLLKP
KAAYELIGELKAAVDLPIHLHTHDTSGNGLLTYKQAIDAGVDIIDTAVASMSGLTSQPSANSLYYALNGFPRHLRTDIEG
MESLSHYWSTVRTYYSDFESDIKSPNTEIYQHEMPGGQYSNLSQQAKSLGLGERFDEVKDMYRRVNFLFGDIVKVTPSSK
VVGDMALYMVQNDLDEQSVITDGYKLDFPESVVSFFKGEIGQPVNGFNKDLQAVILKGQEALTARPGEYLEPVDFEKVRE
LLEEEQQGPVTEQDIISYVLYPKVYEQYIQTRNQYGNLSLLDTPTFFFGMRNGETVEIEIDKGKRLIIKLETISEPDENG
NRTIYYAMNGQARRIYIKDENVHTNANVKPKADKSNPSHIGAQMPGSVTEVKVSVGETVKANQPLLITEAMKMETTIQAP
FDGMIKQVTVNNGDTIATGDLLIEIEKATD

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1154, Percent_Identity=48.0935875216638, Blast_Score=1085, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1154, Percent_Identity=48.0935875216638, Blast_Score=1085, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1154, Percent_Identity=48.0935875216638, Blast_Score=1085, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=456, Percent_Identity=44.9561403508772, Blast_Score=392, Evalue=1e-109,
Organism=Homo sapiens, GI189095269, Length=464, Percent_Identity=44.8275862068966, Blast_Score=371, Evalue=1e-102,
Organism=Homo sapiens, GI65506442, Length=463, Percent_Identity=44.9244060475162, Blast_Score=370, Evalue=1e-102,
Organism=Homo sapiens, GI295821183, Length=463, Percent_Identity=44.9244060475162, Blast_Score=370, Evalue=1e-102,
Organism=Homo sapiens, GI134142062, Length=510, Percent_Identity=30.9803921568627, Blast_Score=236, Evalue=1e-61,
Organism=Homo sapiens, GI38679960, Length=517, Percent_Identity=30.174081237911, Blast_Score=235, Evalue=1e-61,
Organism=Homo sapiens, GI38679971, Length=517, Percent_Identity=30.174081237911, Blast_Score=235, Evalue=2e-61,
Organism=Homo sapiens, GI38679974, Length=517, Percent_Identity=30.174081237911, Blast_Score=235, Evalue=2e-61,
Organism=Homo sapiens, GI38679977, Length=517, Percent_Identity=30.174081237911, Blast_Score=235, Evalue=2e-61,
Organism=Homo sapiens, GI38679967, Length=517, Percent_Identity=30.174081237911, Blast_Score=235, Evalue=2e-61,
Organism=Escherichia coli, GI1789654, Length=451, Percent_Identity=43.0155210643016, Blast_Score=359, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17562816, Length=1150, Percent_Identity=47.8260869565217, Blast_Score=1096, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17567343, Length=456, Percent_Identity=42.5438596491228, Blast_Score=352, Evalue=6e-97,
Organism=Caenorhabditis elegans, GI71987519, Length=463, Percent_Identity=41.6846652267819, Blast_Score=344, Evalue=2e-94,
Organism=Caenorhabditis elegans, GI133931226, Length=492, Percent_Identity=29.0650406504065, Blast_Score=214, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI71997168, Length=511, Percent_Identity=28.7671232876712, Blast_Score=209, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI71997163, Length=511, Percent_Identity=28.7671232876712, Blast_Score=209, Evalue=6e-54,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1161, Percent_Identity=48.9233419465978, Blast_Score=1112, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1158, Percent_Identity=49.9136442141624, Blast_Score=1107, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=450, Percent_Identity=40, Blast_Score=309, Evalue=2e-84,
Organism=Saccharomyces cerevisiae, GI6323863, Length=437, Percent_Identity=35.0114416475973, Blast_Score=239, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6324343, Length=513, Percent_Identity=30.4093567251462, Blast_Score=228, Evalue=4e-60,
Organism=Saccharomyces cerevisiae, GI6322331, Length=300, Percent_Identity=22, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24652212, Length=1160, Percent_Identity=48.7931034482759, Blast_Score=1116, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1160, Percent_Identity=48.7931034482759, Blast_Score=1116, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1160, Percent_Identity=48.7931034482759, Blast_Score=1116, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1160, Percent_Identity=48.7931034482759, Blast_Score=1116, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1160, Percent_Identity=48.7931034482759, Blast_Score=1116, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1168, Percent_Identity=48.5445205479452, Blast_Score=1109, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1168, Percent_Identity=48.5445205479452, Blast_Score=1109, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1168, Percent_Identity=48.5445205479452, Blast_Score=1109, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1168, Percent_Identity=48.5445205479452, Blast_Score=1109, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1168, Percent_Identity=48.5445205479452, Blast_Score=1109, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=457, Percent_Identity=44.2013129102845, Blast_Score=373, Evalue=1e-103,
Organism=Drosophila melanogaster, GI24651759, Length=416, Percent_Identity=43.9903846153846, Blast_Score=332, Evalue=1e-90,
Organism=Drosophila melanogaster, GI24586458, Length=510, Percent_Identity=30.1960784313725, Blast_Score=230, Evalue=5e-60,
Organism=Drosophila melanogaster, GI161076409, Length=510, Percent_Identity=29.8039215686275, Blast_Score=230, Evalue=5e-60,
Organism=Drosophila melanogaster, GI161076407, Length=510, Percent_Identity=30.1960784313725, Blast_Score=230, Evalue=5e-60,
Organism=Drosophila melanogaster, GI24586460, Length=510, Percent_Identity=30.1960784313725, Blast_Score=230, Evalue=5e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 128545; Mature: 128545

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQIKKLLVANRGEIAIRIFRAAAELDISTVAIYSNEDKSSLHRYKADESYLVGSDLGPA
CHHHHHHHHCCCCCEEEEEEEHHHHCCEEEEEEEECCCHHHHHHHCCCCCEEECCCCCCH
ESYLNIERIIDVAKQANVDAIHPGYGFLSENEQFARRCAEEGIKFIGPHLEHLDMFGDKV
HHHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHCCHHHHCCHHHHHHHHHHHH
KARTTAIKADLPVIPGTEGPIKSYELAKEFAEEAGFPLMIKATSGGGGKGMRIVREESEL
HHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEEHHHHH
EDAFHRAKSEAEKSFGNSEVYIERYIDNPKHIEVQVIGDEHGNIVHLFERDCSVQRRHQK
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEEECCCCCEEEEECCCCHHHHHHHH
VVEVAPSVGLSPTLRQRICDAAIQLMENIKYVNAGTVEFLVSGDEFFFIEVNPRVQVEHT
HHHHCCCCCCCHHHHHHHHHHHHHHHHCCEECCCCCEEEEEECCEEEEEEECCCEEEHHH
ITEMVTGIDIVKTQILVAAGADLFGEEINMPQQKDITTLGYAIQCRITTEAPLNDFMPDT
HHHHHHHHHHHHHHHHEECCCHHHHHHCCCCCCCCCEEECEEEEEEEECCCCHHHCCCCC
GTIIAYRSSGGFGVRLDAGDGFQGAEISPYYDSLLVKLSTHAISFKQAEEKMVRSLREMR
CCEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRGVKTNIPFLINVMKNKKFTSGDYTTKFIEETPELFDIQPSLDRGTKTLEYIGNVTING
HCCCCCCCCEEEEECCCCCCCCCCCHHHHHHCCCCCEECCCCCCCCHHHHHHHCCEEECC
FPNVEKRPKPDYELASIPTVSSSKIASFSGTKQLLDEVGPKGVAEWVKKQDDVLLTDTTF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHCCCCEEEEECCH
RDAHQSLLATRVRTKDMINIASKTADVFKDGFSLEMWGGATFDVAYNFLKENPWERLERL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEHHHHHHHHHCCHHHHHHHH
RKAIPNVLFQMLLRASNAVGYKNYPDNVIHKFVQESAKAGIDVFRIFDSLNWVDQMKVAN
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHH
EAVQEAGKISEGTICYTGDILNPERSNIYTLEYYVKLAKELEREGFHILAIKDMAGLLKP
HHHHHHCCCCCCEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHCCEEEEEEHHHHHHHCC
KAAYELIGELKAAVDLPIHLHTHDTSGNGLLTYKQAIDAGVDIIDTAVASMSGLTSQPSA
HHHHHHHHHHHHHEECEEEEEECCCCCCCEEEEHHHHHCCCHHHHHHHHHHCCCCCCCCC
NSLYYALNGFPRHLRTDIEGMESLSHYWSTVRTYYSDFESDIKSPNTEIYQHEMPGGQYS
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCC
NLSQQAKSLGLGERFDEVKDMYRRVNFLFGDIVKVTPSSKVVGDMALYMVQNDLDEQSVI
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHCCCCCHHHC
TDGYKLDFPESVVSFFKGEIGQPVNGFNKDLQAVILKGQEALTARPGEYLEPVDFEKVRE
CCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCHHHCCCCCCCCCCCCHHHHHH
LLEEEQQGPVTEQDIISYVLYPKVYEQYIQTRNQYGNLSLLDTPTFFFGMRNGETVEIEI
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEECCCCCEEEEEE
DKGKRLIIKLETISEPDENGNRTIYYAMNGQARRIYIKDENVHTNANVKPKADKSNPSHI
CCCCEEEEEEEECCCCCCCCCEEEEEEECCCEEEEEEECCCEECCCCCCCCCCCCCCCCC
GAQMPGSVTEVKVSVGETVKANQPLLITEAMKMETTIQAPFDGMIKQVTVNNGDTIATGD
CCCCCCCCEEEEEECCCEECCCCCEEEEEHHHHHHEECCCCCCCEEEEEECCCCEEEECE
LLIEIEKATD
EEEEEECCCC
>Mature Secondary Structure
MKQIKKLLVANRGEIAIRIFRAAAELDISTVAIYSNEDKSSLHRYKADESYLVGSDLGPA
CHHHHHHHHCCCCCEEEEEEEHHHHCCEEEEEEEECCCHHHHHHHCCCCCEEECCCCCCH
ESYLNIERIIDVAKQANVDAIHPGYGFLSENEQFARRCAEEGIKFIGPHLEHLDMFGDKV
HHHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHCCHHHHCCHHHHHHHHHHHH
KARTTAIKADLPVIPGTEGPIKSYELAKEFAEEAGFPLMIKATSGGGGKGMRIVREESEL
HHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEEHHHHH
EDAFHRAKSEAEKSFGNSEVYIERYIDNPKHIEVQVIGDEHGNIVHLFERDCSVQRRHQK
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEEECCCCCEEEEECCCCHHHHHHHH
VVEVAPSVGLSPTLRQRICDAAIQLMENIKYVNAGTVEFLVSGDEFFFIEVNPRVQVEHT
HHHHCCCCCCCHHHHHHHHHHHHHHHHCCEECCCCCEEEEEECCEEEEEEECCCEEEHHH
ITEMVTGIDIVKTQILVAAGADLFGEEINMPQQKDITTLGYAIQCRITTEAPLNDFMPDT
HHHHHHHHHHHHHHHHEECCCHHHHHHCCCCCCCCCEEECEEEEEEEECCCCHHHCCCCC
GTIIAYRSSGGFGVRLDAGDGFQGAEISPYYDSLLVKLSTHAISFKQAEEKMVRSLREMR
CCEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRGVKTNIPFLINVMKNKKFTSGDYTTKFIEETPELFDIQPSLDRGTKTLEYIGNVTING
HCCCCCCCCEEEEECCCCCCCCCCCHHHHHHCCCCCEECCCCCCCCHHHHHHHCCEEECC
FPNVEKRPKPDYELASIPTVSSSKIASFSGTKQLLDEVGPKGVAEWVKKQDDVLLTDTTF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHCCCCEEEEECCH
RDAHQSLLATRVRTKDMINIASKTADVFKDGFSLEMWGGATFDVAYNFLKENPWERLERL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEHHHHHHHHHCCHHHHHHHH
RKAIPNVLFQMLLRASNAVGYKNYPDNVIHKFVQESAKAGIDVFRIFDSLNWVDQMKVAN
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHH
EAVQEAGKISEGTICYTGDILNPERSNIYTLEYYVKLAKELEREGFHILAIKDMAGLLKP
HHHHHHCCCCCCEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHCCEEEEEEHHHHHHHCC
KAAYELIGELKAAVDLPIHLHTHDTSGNGLLTYKQAIDAGVDIIDTAVASMSGLTSQPSA
HHHHHHHHHHHHHEECEEEEEECCCCCCCEEEEHHHHHCCCHHHHHHHHHHCCCCCCCCC
NSLYYALNGFPRHLRTDIEGMESLSHYWSTVRTYYSDFESDIKSPNTEIYQHEMPGGQYS
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCC
NLSQQAKSLGLGERFDEVKDMYRRVNFLFGDIVKVTPSSKVVGDMALYMVQNDLDEQSVI
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHCCCCCHHHC
TDGYKLDFPESVVSFFKGEIGQPVNGFNKDLQAVILKGQEALTARPGEYLEPVDFEKVRE
CCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCHHHCCCCCCCCCCCCHHHHHH
LLEEEQQGPVTEQDIISYVLYPKVYEQYIQTRNQYGNLSLLDTPTFFFGMRNGETVEIEI
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEECCCCCEEEEEE
DKGKRLIIKLETISEPDENGNRTIYYAMNGQARRIYIKDENVHTNANVKPKADKSNPSHI
CCCCEEEEEEEECCCCCCCCCEEEEEEECCCEEEEEEECCCEECCCCCCCCCCCCCCCCC
GAQMPGSVTEVKVSVGETVKANQPLLITEAMKMETTIQAPFDGMIKQVTVNNGDTIATGD
CCCCCCCCEEEEEECCCEECCCCCEEEEEHHHHHHEECCCCCCCEEEEEECCCCEEEECE
LLIEIEKATD
EEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]