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The map label for this gene is purN

Identifier: 82750683

GI number: 82750683

Start: 1018831

End: 1019397

Strand: Direct

Name: purN

Synonym: SAB0939

Alternate gene names: 82750683

Gene position: 1018831-1019397 (Clockwise)

Preceding gene: 82750682

Following gene: 82750684

Centisome position: 37.15

GC content: 31.92

Gene sequence:

>567_bases
ATGGTTAAAATTGCGATTTTTGCATCAGGTTCAGGAAGTAACTTTGAAAATATAGTTGAGCATGTTGAATCAGGAAAACT
TGAAAATATTGAAGTTACGTCGCTATATACGGATCATCAAAATGCGTTTTGTATAGATAGAGCAAAAAAGCATGATATTC
CTGTTTATATTAATGAACCAAAAAAATTTGATTCAAAAGCAGCGTATGAACAACATTTAGTAACATTATTAAATGAAGAT
AAGGTAGAGTGGATTATTTTAGCTGGCTACATGCGTCTAATTGGTCCAGACTTATTAGCTTCATTTGAAGGTAAAATATT
GAATATACATCCATCTCTATTGCCGAAATATAAGGGGATTGACGCAATAGGCCAAGCATATCATAGTGGCGATACTATTA
CTGGTTCGACAGTACATTATGTTGATAGTGGTATGGATACGGGAGAAATTATTGAACAGAGACAATGTGATATTAGACCG
GACGATTCAAAAGAACAATTAGAAGAGAAAGTAAAAAAATTGGAATATGAGTTATATCCAAGTGTTATTGCTAAAATTGT
AAAATAA

Upstream 100 bases:

>100_bases
GCGCTTTGAAGATTTTAGCAGAACAAAATGTGGAAGCCTATCAAATTGGTCATATTGTGAAAAATGAGTCAACTGCAATC
GAATTGTTGGGGGTATAACA

Downstream 100 bases:

>100_bases
GGAGTATGTATGTGATGAAGAAAGCTATTTTGAGCGTATCAAATAAAACAGGTATTGTAGAGTTTGCTAAAGCGTTAACG
CAATTAAATTATGAATTATA

Product: phosphoribosylformylglycinamidine formyltransferase

Products: NA

Alternate protein names: 5'-phosphoribosylglycinamide transformylase; GAR transformylase; GART [H]

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MVKIAIFASGSGSNFENIVEHVESGKLENIEVTSLYTDHQNAFCIDRAKKHDIPVYINEPKKFDSKAAYEQHLVTLLNED
KVEWIILAGYMRLIGPDLLASFEGKILNIHPSLLPKYKGIDAIGQAYHSGDTITGSTVHYVDSGMDTGEIIEQRQCDIRP
DDSKEQLEEKVKKLEYELYPSVIAKIVK

Sequences:

>Translated_188_residues
MVKIAIFASGSGSNFENIVEHVESGKLENIEVTSLYTDHQNAFCIDRAKKHDIPVYINEPKKFDSKAAYEQHLVTLLNED
KVEWIILAGYMRLIGPDLLASFEGKILNIHPSLLPKYKGIDAIGQAYHSGDTITGSTVHYVDSGMDTGEIIEQRQCDIRP
DDSKEQLEEKVKKLEYELYPSVIAKIVK
>Mature_188_residues
MVKIAIFASGSGSNFENIVEHVESGKLENIEVTSLYTDHQNAFCIDRAKKHDIPVYINEPKKFDSKAAYEQHLVTLLNED
KVEWIILAGYMRLIGPDLLASFEGKILNIHPSLLPKYKGIDAIGQAYHSGDTITGSTVHYVDSGMDTGEIIEQRQCDIRP
DDSKEQLEEKVKKLEYELYPSVIAKIVK

Specific function: De novo purine biosynthesis; third step. [C]

COG id: COG0299

COG function: function code F; Folate-dependent phosphoribosylglycinamide formyltransferase PurN

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GART family [H]

Homologues:

Organism=Homo sapiens, GI4503915, Length=181, Percent_Identity=29.8342541436464, Blast_Score=114, Evalue=4e-26,
Organism=Homo sapiens, GI209869995, Length=181, Percent_Identity=29.8342541436464, Blast_Score=114, Evalue=4e-26,
Organism=Homo sapiens, GI209869993, Length=181, Percent_Identity=29.8342541436464, Blast_Score=114, Evalue=4e-26,
Organism=Escherichia coli, GI1788846, Length=183, Percent_Identity=32.2404371584699, Blast_Score=124, Evalue=3e-30,
Organism=Escherichia coli, GI1787483, Length=151, Percent_Identity=27.8145695364238, Blast_Score=75, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17567511, Length=191, Percent_Identity=32.4607329842932, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6320616, Length=198, Percent_Identity=26.7676767676768, Blast_Score=77, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24582400, Length=186, Percent_Identity=33.8709677419355, Blast_Score=128, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002376
- InterPro:   IPR004607 [H]

Pfam domain/function: PF00551 Formyl_trans_N [H]

EC number: =2.1.2.2 [H]

Molecular weight: Translated: 21167; Mature: 21167

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKIAIFASGSGSNFENIVEHVESGKLENIEVTSLYTDHQNAFCIDRAKKHDIPVYINEP
CEEEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEEEECCCCEEEECCCCCCCCCEEECCC
KKFDSKAAYEQHLVTLLNEDKVEWIILAGYMRLIGPDLLASFEGKILNIHPSLLPKYKGI
CCCCHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHCHHHHHHCCCCEEEECHHHCCCCCCH
DAIGQAYHSGDTITGSTVHYVDSGMDTGEIIEQRQCDIRPDDSKEQLEEKVKKLEYELYP
HHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
SVIAKIVK
HHHHHHCC
>Mature Secondary Structure
MVKIAIFASGSGSNFENIVEHVESGKLENIEVTSLYTDHQNAFCIDRAKKHDIPVYINEP
CEEEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEEEECCCCEEEECCCCCCCCCEEECCC
KKFDSKAAYEQHLVTLLNEDKVEWIILAGYMRLIGPDLLASFEGKILNIHPSLLPKYKGI
CCCCHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHCHHHHHHCCCCEEEECHHHCCCCCCH
DAIGQAYHSGDTITGSTVHYVDSGMDTGEIIEQRQCDIRPDDSKEQLEEKVKKLEYELYP
HHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
SVIAKIVK
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA