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The map label for this gene is fabF

Identifier: 82750596

GI number: 82750596

Start: 921329

End: 922573

Strand: Direct

Name: fabF

Synonym: SAB0849

Alternate gene names: 82750596

Gene position: 921329-922573 (Clockwise)

Preceding gene: 82750595

Following gene: 82750599

Centisome position: 33.59

GC content: 39.12

Gene sequence:

>1245_bases
ATGAGTCAAAATAAAAGAGTAGTTATTACAGGTATGGGAGCCCTTTCTCCAATCGGTAATGATGTCAAAACAACATGGGA
GAATGCTCTAAAAGGCGTAAATGGTATCGATAAAATTACACGTATCGATACTGAACCTTATAGCGTTCACTTAGCAGGAG
AACTTAAAAACTTTAATATTGAAGATCATATCGACAAAAAAGAAGCGCGTCGTATGGATAGATTTACTCAATATGCAATT
GTAGCAGCTAGAGAGGCTGTTAAAGATGCGCAATTAGATATCAATGAAAATACTGCAGATCGAATCGGTGTATGGATTGG
TTCTGGTATCGGTGGTATGGAAACATTTGAAATTGCACATAAACAATTAATGGATAAAGGCCCAAGACGTGTGAGTCCAT
TTTTCGTACCAATGTTAATTCCTGATATGGCAACTGGACAAGTATCAATTGACTTAGGTGCAAAAGGACCAAATGGTGCA
ACAGTTACAGCATGTGCAACAGGTACAAACTCAATCGGAGAAGCATTTAAAATTGTGCAACGCGGTGATGCAGATGCAAT
GATTACTGGTGGTACAGAAGCACCAATTACTCATATGGCAATTGCAGGTTTCAGTGCAAGTCGAGCGCTTTCTACAAATG
ATGACATTGAAACAGCATGTCGTCCATTCCAAGAAGGCAGAGACGGTTTTGTTATGGGTGAAGGTGCTGGTATTTTAGTA
ATCGAATCTTTAGAATCAGCACAAGCTCGAGGTGCCAATATCTATGCTGAGATAGTTGGCTATGGTACTACAGGTGATGC
TTATCATATTACAGCGCCAGCTCCAGAAGGTGAAGGCGGTTCTAGAGCAATGCAAGCAGCTATGGATGATGCTGGTATTG
AACCTAAAGATGTACAATACTTAAATGCCCATGGTACAAGTACTCCTGTTGGTGACTTAAATGAAGTTAAAGCTATAAAA
AATACATTTGGTGAAGCAGCTAAACACTTAAAAGTTAGCTCAACAAAATCAATGACTGGTCACTTACTTGGTGCAACAGG
TGGAATTGAAGCAATCTTCTCAGCGTTTTCAATTAAAGACTCTAAAGTCGCACCGACAATTCATGCGGTAACACCAGATC
CAGAATGTGATTTGGATATTGTTCCAAATGAAGCGCAAGACCTTGATATTACTTATGCAATGAGTAATAGCTTAGGATTC
GGTGGACATAACGCAGTATTAGTATTCAAGAAATTTGAAGCATAA

Upstream 100 bases:

>100_bases
GTAAACTCAAAGATGATGATACAATTGTTCTTGTCGGATTCGGTGGCGGCCTAACTTGGGGCGCAATGACAATAAAATGG
GGAAAATAGGAGGATAACGA

Downstream 100 bases:

>100_bases
TTATAAAAATCTGGCTCTATGTCAAATTGGACTGATGCGTTCAATATCGGAAGTTAGGCAACTAAACATTGCTTAACTTC
CTTTTTACTTTTTGGAGCGT

Product: 3-oxoacyl-ACP synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MSQNKRVVITGMGALSPIGNDVKTTWENALKGVNGIDKITRIDTEPYSVHLAGELKNFNIEDHIDKKEARRMDRFTQYAI
VAAREAVKDAQLDINENTADRIGVWIGSGIGGMETFEIAHKQLMDKGPRRVSPFFVPMLIPDMATGQVSIDLGAKGPNGA
TVTACATGTNSIGEAFKIVQRGDADAMITGGTEAPITHMAIAGFSASRALSTNDDIETACRPFQEGRDGFVMGEGAGILV
IESLESAQARGANIYAEIVGYGTTGDAYHITAPAPEGEGGSRAMQAAMDDAGIEPKDVQYLNAHGTSTPVGDLNEVKAIK
NTFGEAAKHLKVSSTKSMTGHLLGATGGIEAIFSAFSIKDSKVAPTIHAVTPDPECDLDIVPNEAQDLDITYAMSNSLGF
GGHNAVLVFKKFEA

Sequences:

>Translated_414_residues
MSQNKRVVITGMGALSPIGNDVKTTWENALKGVNGIDKITRIDTEPYSVHLAGELKNFNIEDHIDKKEARRMDRFTQYAI
VAAREAVKDAQLDINENTADRIGVWIGSGIGGMETFEIAHKQLMDKGPRRVSPFFVPMLIPDMATGQVSIDLGAKGPNGA
TVTACATGTNSIGEAFKIVQRGDADAMITGGTEAPITHMAIAGFSASRALSTNDDIETACRPFQEGRDGFVMGEGAGILV
IESLESAQARGANIYAEIVGYGTTGDAYHITAPAPEGEGGSRAMQAAMDDAGIEPKDVQYLNAHGTSTPVGDLNEVKAIK
NTFGEAAKHLKVSSTKSMTGHLLGATGGIEAIFSAFSIKDSKVAPTIHAVTPDPECDLDIVPNEAQDLDITYAMSNSLGF
GGHNAVLVFKKFEA
>Mature_413_residues
SQNKRVVITGMGALSPIGNDVKTTWENALKGVNGIDKITRIDTEPYSVHLAGELKNFNIEDHIDKKEARRMDRFTQYAIV
AAREAVKDAQLDINENTADRIGVWIGSGIGGMETFEIAHKQLMDKGPRRVSPFFVPMLIPDMATGQVSIDLGAKGPNGAT
VTACATGTNSIGEAFKIVQRGDADAMITGGTEAPITHMAIAGFSASRALSTNDDIETACRPFQEGRDGFVMGEGAGILVI
ESLESAQARGANIYAEIVGYGTTGDAYHITAPAPEGEGGSRAMQAAMDDAGIEPKDVQYLNAHGTSTPVGDLNEVKAIKN
TFGEAAKHLKVSSTKSMTGHLLGATGGIEAIFSAFSIKDSKVAPTIHAVTPDPECDLDIVPNEAQDLDITYAMSNSLGFG
GHNAVLVFKKFEA

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=416, Percent_Identity=44.7115384615385, Blast_Score=347, Evalue=1e-95,
Organism=Homo sapiens, GI223972627, Length=170, Percent_Identity=45.8823529411765, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI41872631, Length=420, Percent_Identity=25, Blast_Score=117, Evalue=3e-26,
Organism=Escherichia coli, GI1787337, Length=410, Percent_Identity=51.4634146341463, Blast_Score=396, Evalue=1e-111,
Organism=Escherichia coli, GI1788663, Length=416, Percent_Identity=39.4230769230769, Blast_Score=238, Evalue=7e-64,
Organism=Caenorhabditis elegans, GI71983541, Length=417, Percent_Identity=35.9712230215827, Blast_Score=254, Evalue=4e-68,
Organism=Caenorhabditis elegans, GI71983535, Length=258, Percent_Identity=41.0852713178295, Blast_Score=197, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI212642053, Length=424, Percent_Identity=27.122641509434, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17550940, Length=350, Percent_Identity=23.1428571428571, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320904, Length=448, Percent_Identity=37.9464285714286, Blast_Score=284, Evalue=2e-77,
Organism=Drosophila melanogaster, GI24644341, Length=420, Percent_Identity=43.0952380952381, Blast_Score=333, Evalue=9e-92,
Organism=Drosophila melanogaster, GI221330659, Length=425, Percent_Identity=25.1764705882353, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI19920632, Length=425, Percent_Identity=25.1764705882353, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24581345, Length=421, Percent_Identity=22.5653206650831, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 43774; Mature: 43643

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQNKRVVITGMGALSPIGNDVKTTWENALKGVNGIDKITRIDTEPYSVHLAGELKNFNI
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCHHHHHEECCCCEEEEEEEECCCCCC
EDHIDKKEARRMDRFTQYAIVAAREAVKDAQLDINENTADRIGVWIGSGIGGMETFEIAH
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCEEEEEEECCCCCHHHHHHHH
KQLMDKGPRRVSPFFVPMLIPDMATGQVSIDLGAKGPNGATVTACATGTNSIGEAFKIVQ
HHHHHCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHH
RGDADAMITGGTEAPITHMAIAGFSASRALSTNDDIETACRPFQEGRDGFVMGEGAGILV
CCCCCEEEECCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCEEE
IESLESAQARGANIYAEIVGYGTTGDAYHITAPAPEGEGGSRAMQAAMDDAGIEPKDVQY
EECCHHHHCCCCEEEEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEE
LNAHGTSTPVGDLNEVKAIKNTFGEAAKHLKVSSTKSMTGHLLGATGGIEAIFSAFSIKD
EECCCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCEEEECCCCHHHHHHHHCCCC
SKVAPTIHAVTPDPECDLDIVPNEAQDLDITYAMSNSLGFGGHNAVLVFKKFEA
CCCCCEEEEECCCCCCCEEECCCCCCCCEEEEEECCCCCCCCCCEEEEEEECCC
>Mature Secondary Structure 
SQNKRVVITGMGALSPIGNDVKTTWENALKGVNGIDKITRIDTEPYSVHLAGELKNFNI
CCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCHHHHHEECCCCEEEEEEEECCCCCC
EDHIDKKEARRMDRFTQYAIVAAREAVKDAQLDINENTADRIGVWIGSGIGGMETFEIAH
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCEEEEEEECCCCCHHHHHHHH
KQLMDKGPRRVSPFFVPMLIPDMATGQVSIDLGAKGPNGATVTACATGTNSIGEAFKIVQ
HHHHHCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHH
RGDADAMITGGTEAPITHMAIAGFSASRALSTNDDIETACRPFQEGRDGFVMGEGAGILV
CCCCCEEEECCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCEEE
IESLESAQARGANIYAEIVGYGTTGDAYHITAPAPEGEGGSRAMQAAMDDAGIEPKDVQY
EECCHHHHCCCCEEEEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEE
LNAHGTSTPVGDLNEVKAIKNTFGEAAKHLKVSSTKSMTGHLLGATGGIEAIFSAFSIKD
EECCCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCEEEECCCCHHHHHHHHCCCC
SKVAPTIHAVTPDPECDLDIVPNEAQDLDITYAMSNSLGFGGHNAVLVFKKFEA
CCCCCEEEEECCCCCCCEEECCCCCCCCEEEEEECCCCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA