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The map label for this gene is hlgA [H]

Identifier: 82750532

GI number: 82750532

Start: 850702

End: 851628

Strand: Direct

Name: hlgA [H]

Synonym: SAB0782

Alternate gene names: 82750532

Gene position: 850702-851628 (Clockwise)

Preceding gene: 82750531

Following gene: 82750533

Centisome position: 31.02

GC content: 33.33

Gene sequence:

>927_bases
ATGTTTAAGAGAAAATTATTAGTTACAACTTTGTCGCTAGGTCTAATTGTTCCTATAGCTACACCATTTCAAGGTTCTAA
GGCTACTACTAATGCAGAAGATATTGGCGACGATGCAGAAGTGATTAAACGTACGGAAGATGTAAGTAGTAGGAAATGGG
GTGTAACACAAAATGTCCAATTTGATTTCGTAAAAGATAAAAAATATAACAAAGACGCATTAATTATTAAGATGCAAGGT
TTTATCAATTCTAGGACAACTTTCAATGATGTTAAACAAAATAGAGCAAATAAAAGAATGGTTTGGCCATTTCAATATAA
TATCGGTCTTACATCAAAAGACCAAAATACGAGCTTAATCAATTATCTTCCTAAAAATAAAATAGAAACAGTTGATGTTG
GTCAAACTTTAGGATATAACATTGGAGGTAAATTCCAGTCAGCACCATCTATAGGCGGAAATGGATCATTTAATTATTCT
AAGAGTATTAAATATTCCCAAAAGAGTTATGTCAGCGAAGTTGAACAACAAAGCTCAAAAACTATTAAGTGGGGGGTTAA
AGCAAATTCTTTTGTTATAGCAGGGCATCGATGGTCTGCTTACGATGAATTATTGTTTATAAGAAATACGACAAGAGGAC
CTAATGCTAGAGACTATTTTGTAGACGATAATGAATTGCCCCCTTTAATAACAAGTGGATTTAATCCGTCTTTTATCGCG
ACAGTATCTCACGAAAAAGATTCAGGCGATACGAGCGAATTTGAAATTACTTACGGTAGAAATATGGATGTTACCTATGC
AACCTACCTTCCTAAACAAGGTCTTTATCCAGAAAGAAAACATAATGAATTTGTAAACAGAAACTTTGTGGTCAAATATG
AAGTGAATTGGAAAACGCACGAAATTAAAGTAAAGGGGCACAACTAA

Upstream 100 bases:

>100_bases
TAACCTTATTGAATTTTTAATAAATTTTTAATTATATAATTATGAATTATGTAATAGTATAAATTTGTATTAAAAATATA
AAGAGAAAGAAAGTGAAACT

Downstream 100 bases:

>100_bases
TATGAAAATTAAGAATATAGTCAAATCATCAGTCGCTACATCAATTACATTTATCATGCTATCAAATACAGTTGATGCAG
CTCAACATATCACACCTGTC

Product: leukocidin chain lukM precursor

Products: NA

Alternate protein names: H-gamma-2; H-gamma-II [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MFKRKLLVTTLSLGLIVPIATPFQGSKATTNAEDIGDDAEVIKRTEDVSSRKWGVTQNVQFDFVKDKKYNKDALIIKMQG
FINSRTTFNDVKQNRANKRMVWPFQYNIGLTSKDQNTSLINYLPKNKIETVDVGQTLGYNIGGKFQSAPSIGGNGSFNYS
KSIKYSQKSYVSEVEQQSSKTIKWGVKANSFVIAGHRWSAYDELLFIRNTTRGPNARDYFVDDNELPPLITSGFNPSFIA
TVSHEKDSGDTSEFEITYGRNMDVTYATYLPKQGLYPERKHNEFVNRNFVVKYEVNWKTHEIKVKGHN

Sequences:

>Translated_308_residues
MFKRKLLVTTLSLGLIVPIATPFQGSKATTNAEDIGDDAEVIKRTEDVSSRKWGVTQNVQFDFVKDKKYNKDALIIKMQG
FINSRTTFNDVKQNRANKRMVWPFQYNIGLTSKDQNTSLINYLPKNKIETVDVGQTLGYNIGGKFQSAPSIGGNGSFNYS
KSIKYSQKSYVSEVEQQSSKTIKWGVKANSFVIAGHRWSAYDELLFIRNTTRGPNARDYFVDDNELPPLITSGFNPSFIA
TVSHEKDSGDTSEFEITYGRNMDVTYATYLPKQGLYPERKHNEFVNRNFVVKYEVNWKTHEIKVKGHN
>Mature_308_residues
MFKRKLLVTTLSLGLIVPIATPFQGSKATTNAEDIGDDAEVIKRTEDVSSRKWGVTQNVQFDFVKDKKYNKDALIIKMQG
FINSRTTFNDVKQNRANKRMVWPFQYNIGLTSKDQNTSLINYLPKNKIETVDVGQTLGYNIGGKFQSAPSIGGNGSFNYS
KSIKYSQKSYVSEVEQQSSKTIKWGVKANSFVIAGHRWSAYDELLFIRNTTRGPNARDYFVDDNELPPLITSGFNPSFIA
TVSHEKDSGDTSEFEITYGRNMDVTYATYLPKQGLYPERKHNEFVNRNFVVKYEVNWKTHEIKVKGHN

Specific function: Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aerolysin family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003963
- InterPro:   IPR001340
- InterPro:   IPR016183 [H]

Pfam domain/function: PF07968 Leukocidin [H]

EC number: NA

Molecular weight: Translated: 35065; Mature: 35065

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKRKLLVTTLSLGLIVPIATPFQGSKATTNAEDIGDDAEVIKRTEDVSSRKWGVTQNVQ
CCCCEEEEEEHHCEEEEEEECCCCCCCCCCCHHHCCCHHHHHHHHHCCCCCCCCCCCCCE
FDFVKDKKYNKDALIIKMQGFINSRTTFNDVKQNRANKRMVWPFQYNIGLTSKDQNTSLI
EEEEECCCCCCCEEEEEEECCCCCCCCHHHHHHCCCCCEEEEEEEEECCCCCCCCCCHHE
NYLPKNKIETVDVGQTLGYNIGGKFQSAPSIGGNGSFNYSKSIKYSQKSYVSEVEQQSSK
EECCCCCCEEEECCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
TIKWGVKANSFVIAGHRWSAYDELLFIRNTTRGPNARDYFVDDNELPPLITSGFNPSFIA
EEEEEECCCCEEEECCCCCCCCEEEEEEECCCCCCCCEEEECCCCCCCCEECCCCCCEEE
TVSHEKDSGDTSEFEITYGRNMDVTYATYLPKQGLYPERKHNEFVNRNFVVKYEVNWKTH
EEECCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHCCCEEEEEEECCEEE
EIKVKGHN
EEEEECCC
>Mature Secondary Structure
MFKRKLLVTTLSLGLIVPIATPFQGSKATTNAEDIGDDAEVIKRTEDVSSRKWGVTQNVQ
CCCCEEEEEEHHCEEEEEEECCCCCCCCCCCHHHCCCHHHHHHHHHCCCCCCCCCCCCCE
FDFVKDKKYNKDALIIKMQGFINSRTTFNDVKQNRANKRMVWPFQYNIGLTSKDQNTSLI
EEEEECCCCCCCEEEEEEECCCCCCCCHHHHHHCCCCCEEEEEEEEECCCCCCCCCCHHE
NYLPKNKIETVDVGQTLGYNIGGKFQSAPSIGGNGSFNYSKSIKYSQKSYVSEVEQQSSK
EECCCCCCEEEECCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
TIKWGVKANSFVIAGHRWSAYDELLFIRNTTRGPNARDYFVDDNELPPLITSGFNPSFIA
EEEEEECCCCEEEECCCCCCCCEEEEEEECCCCCCCCEEEECCCCCCCCEECCCCCCEEE
TVSHEKDSGDTSEFEITYGRNMDVTYATYLPKQGLYPERKHNEFVNRNFVVKYEVNWKTH
EEECCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHCCCEEEEEEECCEEE
EIKVKGHN
EEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA