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The map label for this gene is rnr

Identifier: 82750488

GI number: 82750488

Start: 808775

End: 811147

Strand: Direct

Name: rnr

Synonym: SAB0736

Alternate gene names: 82750488

Gene position: 808775-811147 (Clockwise)

Preceding gene: 82750487

Following gene: 82750489

Centisome position: 29.49

GC content: 34.89

Gene sequence:

>2373_bases
ATGAATTTAAAGCAATCAATAGAAGAGATTATTAATCAACCTGAATATGAACCTATGTCAGTGTCAGATTTTCAAGATGC
ATTAGGTTTAAGCAGTGCCGACTCGTTTAGAGATTTAATTAAGGTGCTTGTGGAGTTAGAACAATCAGGATTAATCGAAC
GTTCGAAAACAGATAGATACCAAAAAAAGCATAGTTCCAAAGGTCAATCGAAATTAATTAAAGGAACATTAAGTCAAAAC
AAAAAAGGTTTTGCTTTCCTAAGACCTGAAGACAAAGATATGGAAGATATATTTATTCCCCCAACAAAAATTAATCGTGC
CTTGGATGGAGATACTGTTATTGTAGAAATCCATCAATCAAAAGGTGAGCATAAAGGTAAAATTGAAGGGGAAGTAAAGT
CAATTGAGAAGCATTCAGTAACTCAAGTGGTTGGTACGTATAGTCAGGCTAGACATTTTGGTTTTGTCATTCCAGATGAT
AAACGAATTATGCAAGATATTTTCATTCCTAAAGGTCAAAGCTTAGGTGCAGTAGATGGTCACAAAGTATTAGTTCAAAT
TACTAAGTATGCTGACGGTTCAGATAATCCAGAAGGACATATTTCTGCTATTTTAGGACATAAAAATGATCCTGGCGTAG
ATATTTTATCTATTATCTATCAACATGGCATAGAAATTGAATTTCCTGATGAAGTGTTACAAGAAGCTGAAGCAACACCA
GACAATATAGAAGATAGTGAAATTAAAGGACGTCATGATTTACGTAATGAATTGACCATCACTATTGATGGCGCGGATGC
TAAAGACTTAGATGACGCAATTAGTGTTAAAAAGTTAGCGAACGGTAATACGCAATTAACTGTAAGTATTGCTGATGTCA
GCTATTATGTAACAGAAGGTTCTGCATTGGATAAAGAGGCCTATGATAGAGCTACAAGTGTATATCTTGTTGACCGTGTA
ATTCCAATGATTCCACATCGATTAAGTAATGGTATTTGTTCATTGAATCCTAATGTTGATCGTTTAACTTTAAGCTGTCG
CATGGAAATCGATGATAGTGGTCGCGTTGTAAAACATGAAATCTTTGATAGTGTGATTCATTCTGATTATCGAATGACGT
ATGATGCGGTAAATCAGATTATTACTGAAAATGATCCTACGATTCGAGAGCAGTATAATGAAATTACGCCTATGCTAGAT
TTAGCACAAGATTTATCAAATCGTTTAATTCAAATGAGAAAACGCCGTGGTGAAATTGATTTTGATATTAGCGAAGCGAA
AGTACTAGTTAACGAAGATGGTATACCTACAGATGTTCAATTGAGACAACGTGGTGAAGGCGAACGTCTTATTGAGTCAT
TCATGTTAATTGCAAATGAAACAGTTGCTGAACATTTTAGTAAGTTAGATGTACCATTTATTTACCGAGTGCATGAGCAA
CCTAAATCAGATCGCTTAAGACAATTCTTTGATTTTATTACAAACTTTGGCATCATGATTAAGGGTACTGGCGAAGATAT
TCATCCAACAACACTTCAAAAGGTTCAAGAAGAAGTAGAAGGTCGACCTGAACAAATGGTCATTTCAACAATGATGTTAC
GTTCAATGCAACAAGCGCATTATGACGATGTGAACTTGGGACATTTTGGCTTATCAGCTGAATATTATACGCATTTTACA
TCACCAATAAGACGTTATCCTGATTTAACAGTTCATCGTTTAATCCGTAAGTATTTAATTGAGAAATCAATGGATAACAA
AGAAGTGAAGCGTTGGGAAGACAAATTGCCTGAGTTAGCTGAACATACTTCTAAACGTGAACGTCGTGCTATTGAGGCAG
AACGTGACACTGATGAATTGAAAAAAGCAGAATATATGATTCAACATATTGGTGATGAATTTGAAGGTATTGTCAGCTCA
GTAGCTAACTTCGGTATGTTCATTGAATTGCCAAATACGATAGAAGGTATGGTTCATATTGCGAATATGACTAATGATTA
TTACCGTTTTGAAGAGCGTCAAATGGCATTAATTGGTGAGCGTCAAGCTAAAGTATTTAGAATTGGGGACACAGTTAAGG
TTAAAGTGACGCATGTTGATGTAGATGAACGATTAATTGATTTTCAAATTGTAGGTATGCCTTTACCGAAAAATGATCGA
TCACAGCGCCCAGCGCGAGGTAAGACAATTCAAGCTAAAACGCGTGGTAAATCATTAGATAAATCGAAATCTGATGATAA
AGGTCATAAGAAAAAAGGTAAGCAACGAAAAGGTAAAAATGAACGTAAAAATGACAAATCAGGAAACAGTAAACATAAGC
CATTTTATAAAGATAAAAGTGTGAAAAAGAAAGCACGTCGTAAGAAAAAATAA

Upstream 100 bases:

>100_bases
TAAAGAAAAAGAACAAGTTTTCGATGATATTTATCAATTTTTAGAGTCATTAGACTGGTCAGAATAAAAAGAGATTTTAA
CATTAGAAAGGAGGGGCATA

Downstream 100 bases:

>100_bases
GCAGCAATGAGGTGAGTATGAATGGCTAAGAAGAAATCACCAGGTACATTAGCGGAAAATCGTAAAGCTAGACATGATTA
TAATATTGAAGACACGATTG

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 790; Mature: 790

Protein sequence:

>790_residues
MNLKQSIEEIINQPEYEPMSVSDFQDALGLSSADSFRDLIKVLVELEQSGLIERSKTDRYQKKHSSKGQSKLIKGTLSQN
KKGFAFLRPEDKDMEDIFIPPTKINRALDGDTVIVEIHQSKGEHKGKIEGEVKSIEKHSVTQVVGTYSQARHFGFVIPDD
KRIMQDIFIPKGQSLGAVDGHKVLVQITKYADGSDNPEGHISAILGHKNDPGVDILSIIYQHGIEIEFPDEVLQEAEATP
DNIEDSEIKGRHDLRNELTITIDGADAKDLDDAISVKKLANGNTQLTVSIADVSYYVTEGSALDKEAYDRATSVYLVDRV
IPMIPHRLSNGICSLNPNVDRLTLSCRMEIDDSGRVVKHEIFDSVIHSDYRMTYDAVNQIITENDPTIREQYNEITPMLD
LAQDLSNRLIQMRKRRGEIDFDISEAKVLVNEDGIPTDVQLRQRGEGERLIESFMLIANETVAEHFSKLDVPFIYRVHEQ
PKSDRLRQFFDFITNFGIMIKGTGEDIHPTTLQKVQEEVEGRPEQMVISTMMLRSMQQAHYDDVNLGHFGLSAEYYTHFT
SPIRRYPDLTVHRLIRKYLIEKSMDNKEVKRWEDKLPELAEHTSKRERRAIEAERDTDELKKAEYMIQHIGDEFEGIVSS
VANFGMFIELPNTIEGMVHIANMTNDYYRFEERQMALIGERQAKVFRIGDTVKVKVTHVDVDERLIDFQIVGMPLPKNDR
SQRPARGKTIQAKTRGKSLDKSKSDDKGHKKKGKQRKGKNERKNDKSGNSKHKPFYKDKSVKKKARRKKK

Sequences:

>Translated_790_residues
MNLKQSIEEIINQPEYEPMSVSDFQDALGLSSADSFRDLIKVLVELEQSGLIERSKTDRYQKKHSSKGQSKLIKGTLSQN
KKGFAFLRPEDKDMEDIFIPPTKINRALDGDTVIVEIHQSKGEHKGKIEGEVKSIEKHSVTQVVGTYSQARHFGFVIPDD
KRIMQDIFIPKGQSLGAVDGHKVLVQITKYADGSDNPEGHISAILGHKNDPGVDILSIIYQHGIEIEFPDEVLQEAEATP
DNIEDSEIKGRHDLRNELTITIDGADAKDLDDAISVKKLANGNTQLTVSIADVSYYVTEGSALDKEAYDRATSVYLVDRV
IPMIPHRLSNGICSLNPNVDRLTLSCRMEIDDSGRVVKHEIFDSVIHSDYRMTYDAVNQIITENDPTIREQYNEITPMLD
LAQDLSNRLIQMRKRRGEIDFDISEAKVLVNEDGIPTDVQLRQRGEGERLIESFMLIANETVAEHFSKLDVPFIYRVHEQ
PKSDRLRQFFDFITNFGIMIKGTGEDIHPTTLQKVQEEVEGRPEQMVISTMMLRSMQQAHYDDVNLGHFGLSAEYYTHFT
SPIRRYPDLTVHRLIRKYLIEKSMDNKEVKRWEDKLPELAEHTSKRERRAIEAERDTDELKKAEYMIQHIGDEFEGIVSS
VANFGMFIELPNTIEGMVHIANMTNDYYRFEERQMALIGERQAKVFRIGDTVKVKVTHVDVDERLIDFQIVGMPLPKNDR
SQRPARGKTIQAKTRGKSLDKSKSDDKGHKKKGKQRKGKNERKNDKSGNSKHKPFYKDKSVKKKARRKKK
>Mature_790_residues
MNLKQSIEEIINQPEYEPMSVSDFQDALGLSSADSFRDLIKVLVELEQSGLIERSKTDRYQKKHSSKGQSKLIKGTLSQN
KKGFAFLRPEDKDMEDIFIPPTKINRALDGDTVIVEIHQSKGEHKGKIEGEVKSIEKHSVTQVVGTYSQARHFGFVIPDD
KRIMQDIFIPKGQSLGAVDGHKVLVQITKYADGSDNPEGHISAILGHKNDPGVDILSIIYQHGIEIEFPDEVLQEAEATP
DNIEDSEIKGRHDLRNELTITIDGADAKDLDDAISVKKLANGNTQLTVSIADVSYYVTEGSALDKEAYDRATSVYLVDRV
IPMIPHRLSNGICSLNPNVDRLTLSCRMEIDDSGRVVKHEIFDSVIHSDYRMTYDAVNQIITENDPTIREQYNEITPMLD
LAQDLSNRLIQMRKRRGEIDFDISEAKVLVNEDGIPTDVQLRQRGEGERLIESFMLIANETVAEHFSKLDVPFIYRVHEQ
PKSDRLRQFFDFITNFGIMIKGTGEDIHPTTLQKVQEEVEGRPEQMVISTMMLRSMQQAHYDDVNLGHFGLSAEYYTHFT
SPIRRYPDLTVHRLIRKYLIEKSMDNKEVKRWEDKLPELAEHTSKRERRAIEAERDTDELKKAEYMIQHIGDEFEGIVSS
VANFGMFIELPNTIEGMVHIANMTNDYYRFEERQMALIGERQAKVFRIGDTVKVKVTHVDVDERLIDFQIVGMPLPKNDR
SQRPARGKTIQAKTRGKSLDKSKSDDKGHKKKGKQRKGKNERKNDKSGNSKHKPFYKDKSVKKKARRKKK

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI134288890, Length=421, Percent_Identity=31.5914489311164, Blast_Score=207, Evalue=5e-53,
Organism=Homo sapiens, GI190014625, Length=633, Percent_Identity=28.5939968404423, Blast_Score=193, Evalue=5e-49,
Organism=Homo sapiens, GI190014623, Length=633, Percent_Identity=28.5939968404423, Blast_Score=193, Evalue=5e-49,
Organism=Homo sapiens, GI219521928, Length=670, Percent_Identity=26.2686567164179, Blast_Score=172, Evalue=1e-42,
Organism=Homo sapiens, GI19115966, Length=670, Percent_Identity=26.2686567164179, Blast_Score=172, Evalue=1e-42,
Organism=Homo sapiens, GI156105695, Length=212, Percent_Identity=28.7735849056604, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI156105693, Length=211, Percent_Identity=28.9099526066351, Blast_Score=75, Evalue=3e-13,
Organism=Escherichia coli, GI87082383, Length=648, Percent_Identity=37.037037037037, Blast_Score=447, Evalue=1e-126,
Organism=Escherichia coli, GI1787542, Length=599, Percent_Identity=26.2103505843072, Blast_Score=161, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17553506, Length=431, Percent_Identity=31.554524361949, Blast_Score=185, Evalue=8e-47,
Organism=Caenorhabditis elegans, GI212645896, Length=627, Percent_Identity=26.3157894736842, Blast_Score=159, Evalue=5e-39,
Organism=Saccharomyces cerevisiae, GI6324552, Length=511, Percent_Identity=29.1585127201566, Blast_Score=187, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6320499, Length=408, Percent_Identity=23.2843137254902, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6323943, Length=384, Percent_Identity=24.4791666666667, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24649634, Length=659, Percent_Identity=28.6798179059181, Blast_Score=206, Evalue=7e-53,
Organism=Drosophila melanogaster, GI19922976, Length=422, Percent_Identity=29.8578199052133, Blast_Score=169, Evalue=7e-42,
Organism=Drosophila melanogaster, GI24654597, Length=422, Percent_Identity=29.8578199052133, Blast_Score=169, Evalue=7e-42,
Organism=Drosophila melanogaster, GI24654592, Length=423, Percent_Identity=30.2600472813239, Blast_Score=169, Evalue=8e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805 [H]

Pfam domain/function: PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 90294; Mature: 90294

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKQSIEEIINQPEYEPMSVSDFQDALGLSSADSFRDLIKVLVELEQSGLIERSKTDRY
CCHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHH
QKKHSSKGQSKLIKGTLSQNKKGFAFLRPEDKDMEDIFIPPTKINRALDGDTVIVEIHQS
HHHHCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCEECCCHHHHHCCCCCEEEEEEECC
KGEHKGKIEGEVKSIEKHSVTQVVGTYSQARHFGFVIPDDKRIMQDIFIPKGQSLGAVDG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEECCCHHHHHHHHCCCCCCCCCCCCC
HKVLVQITKYADGSDNPEGHISAILGHKNDPGVDILSIIYQHGIEIEFPDEVLQEAEATP
CEEEEEEEECCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCEECCHHHHHHHCCCC
DNIEDSEIKGRHDLRNELTITIDGADAKDLDDAISVKKLANGNTQLTVSIADVSYYVTEG
CCCCCCCCCCCHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEEEEEEEEEECC
SALDKEAYDRATSVYLVDRVIPMIPHRLSNGICSLNPNVDRLTLSCRMEIDDSGRVVKHE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEEEEEEECCCCCCHHHH
IFDSVIHSDYRMTYDAVNQIITENDPTIREQYNEITPMLDLAQDLSNRLIQMRKRRGEID
HHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FDISEAKVLVNEDGIPTDVQLRQRGEGERLIESFMLIANETVAEHFSKLDVPFIYRVHEQ
EECCCCEEEECCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
PKSDRLRQFFDFITNFGIMIKGTGEDIHPTTLQKVQEEVEGRPEQMVISTMMLRSMQQAH
CCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
YDDVNLGHFGLSAEYYTHFTSPIRRYPDLTVHRLIRKYLIEKSMDNKEVKRWEDKLPELA
CCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EHTSKRERRAIEAERDTDELKKAEYMIQHIGDEFEGIVSSVANFGMFIELPNTIEGMVHI
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCEEEECCCHHHHHEEH
ANMTNDYYRFEERQMALIGERQAKVFRIGDTVKVKVTHVDVDERLIDFQIVGMPLPKNDR
HHCCCHHHHHHHHHHHHHCCCCCEEEEECCEEEEEEEEECCCHHEEEEEEEECCCCCCCC
SQRPARGKTIQAKTRGKSLDKSKSDDKGHKKKGKQRKGKNERKNDKSGNSKHKPFYKDKS
CCCCCCCCEEEEHHCCCCCCCCCCCCCHHHHHCHHHCCCCCCCCCCCCCCCCCCCCCCHH
VKKKARRKKK
HHHHHHHCCC
>Mature Secondary Structure
MNLKQSIEEIINQPEYEPMSVSDFQDALGLSSADSFRDLIKVLVELEQSGLIERSKTDRY
CCHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHH
QKKHSSKGQSKLIKGTLSQNKKGFAFLRPEDKDMEDIFIPPTKINRALDGDTVIVEIHQS
HHHHCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCEECCCHHHHHCCCCCEEEEEEECC
KGEHKGKIEGEVKSIEKHSVTQVVGTYSQARHFGFVIPDDKRIMQDIFIPKGQSLGAVDG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEECCCHHHHHHHHCCCCCCCCCCCCC
HKVLVQITKYADGSDNPEGHISAILGHKNDPGVDILSIIYQHGIEIEFPDEVLQEAEATP
CEEEEEEEECCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCEECCHHHHHHHCCCC
DNIEDSEIKGRHDLRNELTITIDGADAKDLDDAISVKKLANGNTQLTVSIADVSYYVTEG
CCCCCCCCCCCHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEEEEEEEEEECC
SALDKEAYDRATSVYLVDRVIPMIPHRLSNGICSLNPNVDRLTLSCRMEIDDSGRVVKHE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEEEEEEECCCCCCHHHH
IFDSVIHSDYRMTYDAVNQIITENDPTIREQYNEITPMLDLAQDLSNRLIQMRKRRGEID
HHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FDISEAKVLVNEDGIPTDVQLRQRGEGERLIESFMLIANETVAEHFSKLDVPFIYRVHEQ
EECCCCEEEECCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
PKSDRLRQFFDFITNFGIMIKGTGEDIHPTTLQKVQEEVEGRPEQMVISTMMLRSMQQAH
CCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
YDDVNLGHFGLSAEYYTHFTSPIRRYPDLTVHRLIRKYLIEKSMDNKEVKRWEDKLPELA
CCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EHTSKRERRAIEAERDTDELKKAEYMIQHIGDEFEGIVSSVANFGMFIELPNTIEGMVHI
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCEEEECCCHHHHHEEH
ANMTNDYYRFEERQMALIGERQAKVFRIGDTVKVKVTHVDVDERLIDFQIVGMPLPKNDR
HHCCCHHHHHHHHHHHHHCCCCCEEEEECCEEEEEEEEECCCHHEEEEEEEECCCCCCCC
SQRPARGKTIQAKTRGKSLDKSKSDDKGHKKKGKQRKGKNERKNDKSGNSKHKPFYKDKS
CCCCCCCCEEEEHHCCCCCCCCCCCCCHHHHHCHHHCCCCCCCCCCCCCCCCCCCCCCHH
VKKKARRKKK
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]