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The map label for this gene is est [H]

Identifier: 82750487

GI number: 82750487

Start: 808001

End: 808741

Strand: Direct

Name: est [H]

Synonym: SAB0735

Alternate gene names: 82750487

Gene position: 808001-808741 (Clockwise)

Preceding gene: 82750486

Following gene: 82750488

Centisome position: 29.46

GC content: 34.28

Gene sequence:

>741_bases
ATGCAAATAAAGTTACCAAAGCCTTTCTTTTTTGAGGAAGGTAAACGTGCCGTGTTATTACTACATGGTTTTACAGGCAA
TTCGTCTGATGTTCGTCAATTAGGTCGATTTTTACAAAAGAAAGGTTATACATCGTATACACCGCAATATGAAGGCCATG
CAGCACCACCAGAAGAGATACTTCAATCAAGTCCTTTTGTTTGGTTTAAAGATGCCTTAGATGGCTATGACTACCTTGTT
GAACAAGGTTATGATGAAATCGTTGTTGCTGGCTTGTCTTTAGGTGGCGATTTTGCATTAAAATTAAGCTTAAATCGAGA
TGTAAAGGGTATTGTAACGATGTGTGCTCCTATGGGTGGCAAAACTGAAGGTGCCATTTATGAAGGCTTTTTAGAATATG
CACGTAATTTTAAAAAGTATGAGGGTAAAGATAAAGAAACGATTGATAACGAAATGCATCATTTCAAACCAACTGAAACT
TTAAAAGAATTAAGTGAAGCATTAGATACGATTAAAGATCAAGTTGATGAGGTGTTTGACCCAATTTTAGTGATTCAAGC
AGAAAACGACAATATGATTGATCCACAATCCGCAAATTATATATATGAACATGTAGACTCTGACGAAAAAGATATCAAAT
GGTATAGTCAGTCAGGACATGTTATTACAATTGATAAAGAAAAAGAACAAGTTTTCGATGATATTTATCAATTTTTAGAG
TCATTAGACTGGTCAGAATAA

Upstream 100 bases:

>100_bases
TTATTTATAATTAGAATAATAAAGGACTCATGTTCAATTATTAGAAACATATTCTTTAATTAAGTACGTTTGTTAATTGT
GAAAAAGGAGCGTTAGATTT

Downstream 100 bases:

>100_bases
AAAGAGATTTTAACATTAGAAAGGAGGGGCATAATGAATTTAAAGCAATCAATAGAAGAGATTATTAATCAACCTGAATA
TGAACCTATGTCAGTGTCAG

Product: carboxylesterase precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MQIKLPKPFFFEEGKRAVLLLHGFTGNSSDVRQLGRFLQKKGYTSYTPQYEGHAAPPEEILQSSPFVWFKDALDGYDYLV
EQGYDEIVVAGLSLGGDFALKLSLNRDVKGIVTMCAPMGGKTEGAIYEGFLEYARNFKKYEGKDKETIDNEMHHFKPTET
LKELSEALDTIKDQVDEVFDPILVIQAENDNMIDPQSANYIYEHVDSDEKDIKWYSQSGHVITIDKEKEQVFDDIYQFLE
SLDWSE

Sequences:

>Translated_246_residues
MQIKLPKPFFFEEGKRAVLLLHGFTGNSSDVRQLGRFLQKKGYTSYTPQYEGHAAPPEEILQSSPFVWFKDALDGYDYLV
EQGYDEIVVAGLSLGGDFALKLSLNRDVKGIVTMCAPMGGKTEGAIYEGFLEYARNFKKYEGKDKETIDNEMHHFKPTET
LKELSEALDTIKDQVDEVFDPILVIQAENDNMIDPQSANYIYEHVDSDEKDIKWYSQSGHVITIDKEKEQVFDDIYQFLE
SLDWSE
>Mature_246_residues
MQIKLPKPFFFEEGKRAVLLLHGFTGNSSDVRQLGRFLQKKGYTSYTPQYEGHAAPPEEILQSSPFVWFKDALDGYDYLV
EQGYDEIVVAGLSLGGDFALKLSLNRDVKGIVTMCAPMGGKTEGAIYEGFLEYARNFKKYEGKDKETIDNEMHHFKPTET
LKELSEALDTIKDQVDEVFDPILVIQAENDNMIDPQSANYIYEHVDSDEKDIKWYSQSGHVITIDKEKEQVFDDIYQFLE
SLDWSE

Specific function: Involved in the detoxification of xenobiotics. Shows maximal activity with C6 substrates, with gradually decreasing activity from C8 to C12 substrates. No activity for higher chain length substrates acids rather than long-chain ones [H]

COG id: COG1647

COG function: function code R; Esterase/lipase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipase/esterase LIP3/BchO family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012354
- InterPro:   IPR001375 [H]

Pfam domain/function: PF00326 Peptidase_S9 [H]

EC number: =3.1.1.1 [H]

Molecular weight: Translated: 28195; Mature: 28195

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIKLPKPFFFEEGKRAVLLLHGFTGNSSDVRQLGRFLQKKGYTSYTPQYEGHAAPPEEI
CCCCCCCCHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHH
LQSSPFVWFKDALDGYDYLVEQGYDEIVVAGLSLGGDFALKLSLNRDVKGIVTMCAPMGG
HCCCCCEEEHHHHCHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHCCCCC
KTEGAIYEGFLEYARNFKKYEGKDKETIDNEMHHFKPTETLKELSEALDTIKDQVDEVFD
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
PILVIQAENDNMIDPQSANYIYEHVDSDEKDIKWYSQSGHVITIDKEKEQVFDDIYQFLE
CEEEEEECCCCCCCCCCCCHHHHHCCCCHHHHEEECCCCCEEEEECHHHHHHHHHHHHHH
SLDWSE
HCCCCC
>Mature Secondary Structure
MQIKLPKPFFFEEGKRAVLLLHGFTGNSSDVRQLGRFLQKKGYTSYTPQYEGHAAPPEEI
CCCCCCCCHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHH
LQSSPFVWFKDALDGYDYLVEQGYDEIVVAGLSLGGDFALKLSLNRDVKGIVTMCAPMGG
HCCCCCEEEHHHHCHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHCCCCC
KTEGAIYEGFLEYARNFKKYEGKDKETIDNEMHHFKPTETLKELSEALDTIKDQVDEVFD
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
PILVIQAENDNMIDPQSANYIYEHVDSDEKDIKWYSQSGHVITIDKEKEQVFDDIYQFLE
CEEEEEECCCCCCCCCCCCHHHHHCCCCHHHHEEECCCCCEEEEECHHHHHHHHHHHHHH
SLDWSE
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1369099 [H]