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The map label for this gene is treA [H]

Identifier: 82750182

GI number: 82750182

Start: 465966

End: 467606

Strand: Direct

Name: treA [H]

Synonym: SAB0424

Alternate gene names: 82750182

Gene position: 465966-467606 (Clockwise)

Preceding gene: 82750181

Following gene: 82750183

Centisome position: 16.99

GC content: 36.14

Gene sequence:

>1641_bases
GTGTCGAAAGAAATAGATTGGAGAAAATCCGTTGTATATCAAATTTATCCTAAGTCGTTTAATGATACGACGGGGAATGG
TATAGGAGATATTAACGGAATTATAGAAAAATTGGATTATATCAAGTTATTGGGTGTTGATTATATTTGGTTAACACCAG
TGTATGAATCACCGATGAATGATAATGGCTATGATATCAGCAATTATTTAGAAATCAATGAAGACTTTGGAACGATGGAT
GATTTTGAAAAGTTAATCAAAGTTGCTCATCAAAAAGACTTGAAAGTGATGTTAGATATTGTCATTAATCATACGTCTAC
GGAGCATGAATGGTTTAAAGAAGCCCGTAAATCTAAAGACAACTCTTATAGAGATTATTACTTTTTCAGATCATCTGAAG
ACGGACCGCCAACAAATTGGTATTCTAAATTTGGTGGTAATGCATGGAAGTATGATTCTGAGACAGATGAATATTATTTA
CATTTATTTGATGTCAGTCAAGCTGATTTAAATTGGGATAATCCGGAAGTACGTCAATCGTTATATCGCATTGTCAATCA
TTGGATAGACTTCGGCGTTGATGGTTTTCGATTTGATGTCATTAACTTAATTTCTAAAGGTGAATTTAAGGACTCTGACA
AAATAGGTAAAGAATTTTATACGGATGGTCCTAGAGTGCATGAGTTTCTGCATGAATTAAATCGTCAAACGTTTGGTAAC
ACTGACATGATGACTGTAGGAGAAATGTCTTCGACGACGATTGAAAATTGTATTAAGTATACACAGCCAGAACGCCAAGA
ATTGAATAGTGTTTTTAATTTTCATCATCTAAAGGTTGATTATGTTGATGGTGAAAAGTGGACAAATGCGAAGCTTGATT
TTCATAAGTTAAAGGAAATTCTGATGCAATGGCAACGAGGTATTTATGACGGTGGCGGATGGAACGCGATTTTCTGGTGT
AATCATGATCAGCCACGGGTAGTGTCTAGATTTGGTGATGATACGTCGGAAGAGATGAGGATACAAAGTGCTAAAATGTT
AGCTATCGCACTGCATATGTTGCAAGGGACGCCATATATTTACCAAGGTGAAGAAATTGGTATGACGGACCCACATTTTA
CATCAATAGCACAATATCGTGATGTTGAATCGATTAATGCCTACCATCAGTTGTTAAGTGAAGGGCATGCTGAAGCGGAT
GTGTTAGCGATTTTAGGACAGAAGTCACGAGACAATTCGAGAACGCCTATGCAATGGAGTGATGATGTTAATGCTGGATT
TACAGCTGGTAAGCCTTGGATTGATATTTCGGAAAATTATCATCAGGTCAACGTTAGACAAGCACTTCAGAATAAAGATT
CTATTTTCTATACGTATCAAAAATTAATACAATTAAGACATACGCATGATATTATTACGTATGGAGACATTGTGCCACGT
TTTATGGATTATGATCATTTATTTGTTTATGAACGTCATTATAAGAATCAACAATGGCTAGTAATTGCGAATTTCTCAGC
ATCGGCTGTTGATTTGCCAGAAGGATTGGCTAGCGAAGGTCGTGTTGTGATTCAAACAGGCACGGTGGAAAATAATACGA
TAAGCGGGTTTGGTGCAATTGTAATCGAAACAAACGCGTAA

Upstream 100 bases:

>100_bases
TAGTAAACAAAAAGCGAAAGAAATTGTTGAAGATTAATAAAATAAAAAAGGGGCGTTCGTTATTTGGACGTCCTTTATTA
CGTTATAAGGTGGTAATTGT

Downstream 100 bases:

>100_bases
AATAAATTGAGTGGATGCGTTTATATGGTGAAGCAAAAGAAGTTTATGAAGATTTATGAGGCGTTGAAAGAAGATATACT
AAACGGGCAGATTCAATATG

Product: alpha-glucosidase

Products: NA

Alternate protein names: Alpha,alpha-phosphotrehalase [H]

Number of amino acids: Translated: 546; Mature: 545

Protein sequence:

>546_residues
MSKEIDWRKSVVYQIYPKSFNDTTGNGIGDINGIIEKLDYIKLLGVDYIWLTPVYESPMNDNGYDISNYLEINEDFGTMD
DFEKLIKVAHQKDLKVMLDIVINHTSTEHEWFKEARKSKDNSYRDYYFFRSSEDGPPTNWYSKFGGNAWKYDSETDEYYL
HLFDVSQADLNWDNPEVRQSLYRIVNHWIDFGVDGFRFDVINLISKGEFKDSDKIGKEFYTDGPRVHEFLHELNRQTFGN
TDMMTVGEMSSTTIENCIKYTQPERQELNSVFNFHHLKVDYVDGEKWTNAKLDFHKLKEILMQWQRGIYDGGGWNAIFWC
NHDQPRVVSRFGDDTSEEMRIQSAKMLAIALHMLQGTPYIYQGEEIGMTDPHFTSIAQYRDVESINAYHQLLSEGHAEAD
VLAILGQKSRDNSRTPMQWSDDVNAGFTAGKPWIDISENYHQVNVRQALQNKDSIFYTYQKLIQLRHTHDIITYGDIVPR
FMDYDHLFVYERHYKNQQWLVIANFSASAVDLPEGLASEGRVVIQTGTVENNTISGFGAIVIETNA

Sequences:

>Translated_546_residues
MSKEIDWRKSVVYQIYPKSFNDTTGNGIGDINGIIEKLDYIKLLGVDYIWLTPVYESPMNDNGYDISNYLEINEDFGTMD
DFEKLIKVAHQKDLKVMLDIVINHTSTEHEWFKEARKSKDNSYRDYYFFRSSEDGPPTNWYSKFGGNAWKYDSETDEYYL
HLFDVSQADLNWDNPEVRQSLYRIVNHWIDFGVDGFRFDVINLISKGEFKDSDKIGKEFYTDGPRVHEFLHELNRQTFGN
TDMMTVGEMSSTTIENCIKYTQPERQELNSVFNFHHLKVDYVDGEKWTNAKLDFHKLKEILMQWQRGIYDGGGWNAIFWC
NHDQPRVVSRFGDDTSEEMRIQSAKMLAIALHMLQGTPYIYQGEEIGMTDPHFTSIAQYRDVESINAYHQLLSEGHAEAD
VLAILGQKSRDNSRTPMQWSDDVNAGFTAGKPWIDISENYHQVNVRQALQNKDSIFYTYQKLIQLRHTHDIITYGDIVPR
FMDYDHLFVYERHYKNQQWLVIANFSASAVDLPEGLASEGRVVIQTGTVENNTISGFGAIVIETNA
>Mature_545_residues
SKEIDWRKSVVYQIYPKSFNDTTGNGIGDINGIIEKLDYIKLLGVDYIWLTPVYESPMNDNGYDISNYLEINEDFGTMDD
FEKLIKVAHQKDLKVMLDIVINHTSTEHEWFKEARKSKDNSYRDYYFFRSSEDGPPTNWYSKFGGNAWKYDSETDEYYLH
LFDVSQADLNWDNPEVRQSLYRIVNHWIDFGVDGFRFDVINLISKGEFKDSDKIGKEFYTDGPRVHEFLHELNRQTFGNT
DMMTVGEMSSTTIENCIKYTQPERQELNSVFNFHHLKVDYVDGEKWTNAKLDFHKLKEILMQWQRGIYDGGGWNAIFWCN
HDQPRVVSRFGDDTSEEMRIQSAKMLAIALHMLQGTPYIYQGEEIGMTDPHFTSIAQYRDVESINAYHQLLSEGHAEADV
LAILGQKSRDNSRTPMQWSDDVNAGFTAGKPWIDISENYHQVNVRQALQNKDSIFYTYQKLIQLRHTHDIITYGDIVPRF
MDYDHLFVYERHYKNQQWLVIANFSASAVDLPEGLASEGRVVIQTGTVENNTISGFGAIVIETNA

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=561, Percent_Identity=28.1639928698752, Blast_Score=229, Evalue=4e-60,
Organism=Escherichia coli, GI1790687, Length=503, Percent_Identity=56.2624254473161, Blast_Score=596, Evalue=1e-171,
Organism=Escherichia coli, GI1786604, Length=215, Percent_Identity=27.4418604651163, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI25147709, Length=537, Percent_Identity=23.2774674115456, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI32565753, Length=202, Percent_Identity=27.7227722772277, Blast_Score=99, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6322245, Length=545, Percent_Identity=39.6330275229358, Blast_Score=370, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6321726, Length=539, Percent_Identity=38.961038961039, Blast_Score=365, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6322241, Length=539, Percent_Identity=38.961038961039, Blast_Score=356, Evalue=6e-99,
Organism=Saccharomyces cerevisiae, GI6322021, Length=539, Percent_Identity=38.961038961039, Blast_Score=356, Evalue=6e-99,
Organism=Saccharomyces cerevisiae, GI6324416, Length=539, Percent_Identity=39.1465677179963, Blast_Score=355, Evalue=9e-99,
Organism=Saccharomyces cerevisiae, GI6321731, Length=553, Percent_Identity=37.6130198915009, Blast_Score=336, Evalue=5e-93,
Organism=Saccharomyces cerevisiae, GI6319776, Length=553, Percent_Identity=37.4321880650995, Blast_Score=335, Evalue=1e-92,
Organism=Drosophila melanogaster, GI24583745, Length=569, Percent_Identity=33.2161687170475, Blast_Score=270, Evalue=2e-72,
Organism=Drosophila melanogaster, GI221330053, Length=590, Percent_Identity=31.864406779661, Blast_Score=270, Evalue=2e-72,
Organism=Drosophila melanogaster, GI24586599, Length=545, Percent_Identity=31.9266055045872, Blast_Score=265, Evalue=5e-71,
Organism=Drosophila melanogaster, GI24586597, Length=538, Percent_Identity=32.1561338289963, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24586593, Length=500, Percent_Identity=32.8, Blast_Score=263, Evalue=3e-70,
Organism=Drosophila melanogaster, GI24583747, Length=567, Percent_Identity=33.1569664902998, Blast_Score=260, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24583749, Length=567, Percent_Identity=33.1569664902998, Blast_Score=260, Evalue=2e-69,
Organism=Drosophila melanogaster, GI24586591, Length=496, Percent_Identity=34.0725806451613, Blast_Score=250, Evalue=1e-66,
Organism=Drosophila melanogaster, GI45549022, Length=541, Percent_Identity=30.3142329020333, Blast_Score=241, Evalue=1e-63,
Organism=Drosophila melanogaster, GI24586589, Length=492, Percent_Identity=31.9105691056911, Blast_Score=236, Evalue=4e-62,
Organism=Drosophila melanogaster, GI24586587, Length=512, Percent_Identity=30.078125, Blast_Score=215, Evalue=8e-56,
Organism=Drosophila melanogaster, GI281360393, Length=448, Percent_Identity=30.5803571428571, Blast_Score=195, Evalue=6e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR012769 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.93 [H]

Molecular weight: Translated: 63512; Mature: 63381

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKEIDWRKSVVYQIYPKSFNDTTGNGIGDINGIIEKLDYIKLLGVDYIWLTPVYESPMN
CCCCCCCHHCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCC
DNGYDISNYLEINEDFGTMDDFEKLIKVAHQKDLKVMLDIVINHTSTEHEWFKEARKSKD
CCCCCCHHEEEECCCCCCHHHHHHHHHHHHHCCHHEEEHHHHCCCCCHHHHHHHHHHCCC
NSYRDYYFFRSSEDGPPTNWYSKFGGNAWKYDSETDEYYLHLFDVSQADLNWDNPEVRQS
CCCCEEEEEECCCCCCCCHHHHHHCCCCEECCCCCCCEEEEEEECCCCCCCCCCHHHHHH
LYRIVNHWIDFGVDGFRFDVINLISKGEFKDSDKIGKEFYTDGPRVHEFLHELNRQTFGN
HHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCC
TDMMTVGEMSSTTIENCIKYTQPERQELNSVFNFHHLKVDYVDGEKWTNAKLDFHKLKEI
CCCEEECCCCHHHHHHHHHCCCCHHHHHHHHHCEEEEEEEEECCCCCCCCCCCHHHHHHH
LMQWQRGIYDGGGWNAIFWCNHDQPRVVSRFGDDTSEEMRIQSAKMLAIALHMLQGTPYI
HHHHHHCCCCCCCCEEEEEECCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEE
YQGEEIGMTDPHFTSIAQYRDVESINAYHQLLSEGHAEADVLAILGQKSRDNSRTPMQWS
EECCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHEEECCCCCCCCCCCCCCC
DDVNAGFTAGKPWIDISENYHQVNVRQALQNKDSIFYTYQKLIQLRHTHDIITYGDIVPR
CCCCCCCCCCCCCEECCCCCEEEHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEHHHHHHH
FMDYDHLFVYERHYKNQQWLVIANFSASAVDLPEGLASEGRVVIQTGTVENNTISGFGAI
HCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEE
VIETNA
EEEECC
>Mature Secondary Structure 
SKEIDWRKSVVYQIYPKSFNDTTGNGIGDINGIIEKLDYIKLLGVDYIWLTPVYESPMN
CCCCCCHHCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCC
DNGYDISNYLEINEDFGTMDDFEKLIKVAHQKDLKVMLDIVINHTSTEHEWFKEARKSKD
CCCCCCHHEEEECCCCCCHHHHHHHHHHHHHCCHHEEEHHHHCCCCCHHHHHHHHHHCCC
NSYRDYYFFRSSEDGPPTNWYSKFGGNAWKYDSETDEYYLHLFDVSQADLNWDNPEVRQS
CCCCEEEEEECCCCCCCCHHHHHHCCCCEECCCCCCCEEEEEEECCCCCCCCCCHHHHHH
LYRIVNHWIDFGVDGFRFDVINLISKGEFKDSDKIGKEFYTDGPRVHEFLHELNRQTFGN
HHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCC
TDMMTVGEMSSTTIENCIKYTQPERQELNSVFNFHHLKVDYVDGEKWTNAKLDFHKLKEI
CCCEEECCCCHHHHHHHHHCCCCHHHHHHHHHCEEEEEEEEECCCCCCCCCCCHHHHHHH
LMQWQRGIYDGGGWNAIFWCNHDQPRVVSRFGDDTSEEMRIQSAKMLAIALHMLQGTPYI
HHHHHHCCCCCCCCEEEEEECCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEE
YQGEEIGMTDPHFTSIAQYRDVESINAYHQLLSEGHAEADVLAILGQKSRDNSRTPMQWS
EECCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHEEECCCCCCCCCCCCCCC
DDVNAGFTAGKPWIDISENYHQVNVRQALQNKDSIFYTYQKLIQLRHTHDIITYGDIVPR
CCCCCCCCCCCCCEECCCCCEEEHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEHHHHHHH
FMDYDHLFVYERHYKNQQWLVIANFSASAVDLPEGLASEGRVVIQTGTVENNTISGFGAI
HCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEE
VIETNA
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7651129; 8969503; 9384377; 7751281 [H]