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The map label for this gene is treR [H]

Identifier: 82750183

GI number: 82750183

Start: 467652

End: 468359

Strand: Direct

Name: treR [H]

Synonym: SAB0425

Alternate gene names: 82750183

Gene position: 467652-468359 (Clockwise)

Preceding gene: 82750182

Following gene: 82750184

Centisome position: 17.05

GC content: 33.76

Gene sequence:

>708_bases
ATGAAGATTTATGAGGCGTTGAAAGAAGATATACTAAACGGGCAGATTCAATATGGTGAACAAATTCCGTCTGAACATGA
TTTGGTGCAATTGTACCAGTCATCTCGAGAGACCGTGCGTAAGGCATTAGATTTGTTGGCATTAGACGGTATGATTCAAA
AGATTCATGGTAAAGGGTCACTTGTCATTTATCAGGAGGTTACAGAGTTTCCATTTTCTGAACTTGTTAGTTTTAAAGAA
ATGCAAGAAGAAATGGGTGTCGCATATTTAACTGAAGTTGTTGTGAATGAGGTTGTTGAAGCGCATGAAGTTCCAGAAGT
TCAACATGCTTTAAACATCAATTCTAGTGAATCACTCATTCATATTGTTAGAACTCGTCGGCTTAACCAACATGTGAAGA
TTGTTGATGAAGATTATTTTCTAAAGTCGATTGTTTCAGATATAGGTAATGATGTTGCGAGTGATTCTATTTATGATTAT
TTGGAAAAGGTATTAAATCTTAATATTAGTTATTCAAGTAAGTCTATTACTTTTGAACCGTTTGATGAACAAGCATATCA
ATTGTTTGGGGATGTATCGGTGGCTTATTCAGCAACAGTTCGAAGTATTGTGTATTTAGAAAATACAATGCCGTTTCAAT
ATAATATTTCAAAACATCTTGCAAATGAATTTAAATTTAATGACTTCTCAAGACGTCGTACAAAGTAA

Upstream 100 bases:

>100_bases
GGAAAATAATACGATAAGCGGGTTTGGTGCAATTGTAATCGAAACAAACGCGTAAAATAAATTGAGTGGATGCGTTTATA
TGGTGAAGCAAAAGAAGTTT

Downstream 100 bases:

>100_bases
ACAATGATATAAATGATTTATACTTGCAATTAACTATTAAAATATAGTAATATATATCTTGCCGTGCTAGGTGGGGAGGT
AGCGGTTCCCTGTACTCGAA

Product: trehalose operon transcriptional repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MKIYEALKEDILNGQIQYGEQIPSEHDLVQLYQSSRETVRKALDLLALDGMIQKIHGKGSLVIYQEVTEFPFSELVSFKE
MQEEMGVAYLTEVVVNEVVEAHEVPEVQHALNINSSESLIHIVRTRRLNQHVKIVDEDYFLKSIVSDIGNDVASDSIYDY
LEKVLNLNISYSSKSITFEPFDEQAYQLFGDVSVAYSATVRSIVYLENTMPFQYNISKHLANEFKFNDFSRRRTK

Sequences:

>Translated_235_residues
MKIYEALKEDILNGQIQYGEQIPSEHDLVQLYQSSRETVRKALDLLALDGMIQKIHGKGSLVIYQEVTEFPFSELVSFKE
MQEEMGVAYLTEVVVNEVVEAHEVPEVQHALNINSSESLIHIVRTRRLNQHVKIVDEDYFLKSIVSDIGNDVASDSIYDY
LEKVLNLNISYSSKSITFEPFDEQAYQLFGDVSVAYSATVRSIVYLENTMPFQYNISKHLANEFKFNDFSRRRTK
>Mature_235_residues
MKIYEALKEDILNGQIQYGEQIPSEHDLVQLYQSSRETVRKALDLLALDGMIQKIHGKGSLVIYQEVTEFPFSELVSFKE
MQEEMGVAYLTEVVVNEVVEAHEVPEVQHALNINSSESLIHIVRTRRLNQHVKIVDEDYFLKSIVSDIGNDVASDSIYDY
LEKVLNLNISYSSKSITFEPFDEQAYQLFGDVSVAYSATVRSIVYLENTMPFQYNISKHLANEFKFNDFSRRRTK

Specific function: Repressor for the trehalose operon (treP and treA). Binds trehalose-6-phosphate, which probably acts as an inducer [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=237, Percent_Identity=24.8945147679325, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI87082252, Length=137, Percent_Identity=31.3868613138686, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR012770
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27089; Mature: 27089

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIYEALKEDILNGQIQYGEQIPSEHDLVQLYQSSRETVRKALDLLALDGMIQKIHGKGS
CCHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LVIYQEVTEFPFSELVSFKEMQEEMGVAYLTEVVVNEVVEAHEVPEVQHALNINSSESLI
EEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHH
HIVRTRRLNQHVKIVDEDYFLKSIVSDIGNDVASDSIYDYLEKVLNLNISYSSKSITFEP
HHHHHHHHCCHHEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEECCCCCEECC
FDEQAYQLFGDVSVAYSATVRSIVYLENTMPFQYNISKHLANEFKFNDFSRRRTK
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHCCCCCHHHHCCC
>Mature Secondary Structure
MKIYEALKEDILNGQIQYGEQIPSEHDLVQLYQSSRETVRKALDLLALDGMIQKIHGKGS
CCHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LVIYQEVTEFPFSELVSFKEMQEEMGVAYLTEVVVNEVVEAHEVPEVQHALNINSSESLI
EEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHH
HIVRTRRLNQHVKIVDEDYFLKSIVSDIGNDVASDSIYDYLEKVLNLNISYSSKSITFEP
HHHHHHHHCCHHEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEECCCCCEECC
FDEQAYQLFGDVSVAYSATVRSIVYLENTMPFQYNISKHLANEFKFNDFSRRRTK
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8917076; 8969503; 9384377; 7651129; 8755887 [H]