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The map label for this gene is treP [H]

Identifier: 82750181

GI number: 82750181

Start: 464475

End: 465902

Strand: Direct

Name: treP [H]

Synonym: SAB0423

Alternate gene names: 82750181

Gene position: 464475-465902 (Clockwise)

Preceding gene: 82750180

Following gene: 82750182

Centisome position: 16.94

GC content: 37.54

Gene sequence:

>1428_bases
ATGGCTGTAAAAAGAGAAGATGTAAAAGCCATCGTAACCGCTATTGGGGGAAAAGAAAATCTTGAAGCTGCAACGCATTG
TGTAACACGATTACGTTTAGTGCTGAAGGATGAAAGTAAAGTTGATAAAGACGCATTAAGTAATAAGGCGTTGGTCAAGG
GGCAGTTCAAAGCAGACCATCAATATCAAATTGTCATTGGTCCAGGAACAGTCGATGAAGTGTATAAGCAGTTTATTGAT
GAAACAGGTGCTCAAGAAGCTTCGAAAGATGAAGCGAAACAAGCAGCTGCGCAAAAAGGGAATCCAGTACAACGTTTGAT
CAAATTGTTGGGGGATATTTTTATACCAATATTACCTGCGATTGTGACAGCTGGTTTGTTAATGGGGATCAATAATTTAC
TTACAATGAAAGGTTTATTTGGTCCAAAAGCACTTATTGAGATGTATCCACAAATTGCTGATATTTCAAACATCATTAAT
GTGATTGCGAGTACGGCATTTATTTTCTTACCAGCATTAATTGGTTGGAGTAGTATGCGTGTATTTGGTGGTAGTCCGAT
TCTAGGCTTAGTCTTAGGTTTGATTTTAATGCACCCGCAATTAGTATCTCAGTATGATTTGGCAAAAGGGAATATTCCGA
CGTGGAACTTATTTGGCTTAGAGATTAAGCAGTTGAATTACCAAGGTCAAGTGTTGCCAGTTTTAATTGCAGCTTATGTT
CTAGCTAAAATTGAAAAAGGATTAAATAAAGTCGTTCACGATTCGATAAAAATGTTGGTCGTTGGACCCGTAGCGCTTTT
AGTTACTGGATTTTTAGCATTTATTATCATTGGACCAGTTGCATTATTGATTGGTACAGGTATTACATCTGGTGTTACAT
TTATATTCCAACATGCAGGATGGCTTGGCGGAGCAATATATGGATTGTTATATGCACCACTTGTAATTACAGGACTACAC
CATATGTTTTTAGCAGTAGATTTCCAATTGATGGGTAGCAGCTTAGGTGGTACGTACTTATGGCCAATCGTTGCGATTTC
AAATATTTGTCAGGGGTCTGCAGCATTTGGAGCATGGTTTGTCTATAAACGTCGTAAAATGGTTAAAGAAGAAGGCTTGG
CATTAACATCTGGTATTTCTGGTATGTTAGGTGTTACTGAACCAGCTATGTTTGGTGTGAACTTACCTCTGAAATATCCA
TTTATCGCTGCGATATCAACGTCTTGTGTATTGGGGGCAATCGTTGGTATGAATAACGTACTTGGAAAAGTTGGTGTTGG
TGGTGTGCCAGCATTCATTTCAATTCAAAAAGAATTTTGGCCAGTATATCTTATTGTGACAGCTATTGCTATTGTTGTAC
CATGTATACTAACAATTGTGATGTCTCATTTTAGTAAACAAAAAGCGAAAGAAATTGTTGAAGATTAA

Upstream 100 bases:

>100_bases
CCAGATAATTGTGACAAAATAAAAATATTTTGTTGAAAGCCTTTACATAACTTGTCTAGACAAGTTATACTCGTTTTAAG
ACATTAAGGGAGTGAAATAT

Downstream 100 bases:

>100_bases
TAAAATAAAAAAGGGGCGTTCGTTATTTGGACGTCCTTTATTACGTTATAAGGTGGTAATTGTGTGTCGAAAGAAATAGA
TTGGAGAAAATCCGTTGTAT

Product: PTS system trehalose-specific IIBC component

Products: NA

Alternate protein names: EIIBC-Tre; EII-Tre; Trehalose-specific phosphotransferase enzyme IIB component; PTS system trehalose-specific EIIB component; Trehalose permease IIC component; PTS system trehalose-specific EIIC component [H]

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MAVKREDVKAIVTAIGGKENLEAATHCVTRLRLVLKDESKVDKDALSNKALVKGQFKADHQYQIVIGPGTVDEVYKQFID
ETGAQEASKDEAKQAAAQKGNPVQRLIKLLGDIFIPILPAIVTAGLLMGINNLLTMKGLFGPKALIEMYPQIADISNIIN
VIASTAFIFLPALIGWSSMRVFGGSPILGLVLGLILMHPQLVSQYDLAKGNIPTWNLFGLEIKQLNYQGQVLPVLIAAYV
LAKIEKGLNKVVHDSIKMLVVGPVALLVTGFLAFIIIGPVALLIGTGITSGVTFIFQHAGWLGGAIYGLLYAPLVITGLH
HMFLAVDFQLMGSSLGGTYLWPIVAISNICQGSAAFGAWFVYKRRKMVKEEGLALTSGISGMLGVTEPAMFGVNLPLKYP
FIAAISTSCVLGAIVGMNNVLGKVGVGGVPAFISIQKEFWPVYLIVTAIAIVVPCILTIVMSHFSKQKAKEIVED

Sequences:

>Translated_475_residues
MAVKREDVKAIVTAIGGKENLEAATHCVTRLRLVLKDESKVDKDALSNKALVKGQFKADHQYQIVIGPGTVDEVYKQFID
ETGAQEASKDEAKQAAAQKGNPVQRLIKLLGDIFIPILPAIVTAGLLMGINNLLTMKGLFGPKALIEMYPQIADISNIIN
VIASTAFIFLPALIGWSSMRVFGGSPILGLVLGLILMHPQLVSQYDLAKGNIPTWNLFGLEIKQLNYQGQVLPVLIAAYV
LAKIEKGLNKVVHDSIKMLVVGPVALLVTGFLAFIIIGPVALLIGTGITSGVTFIFQHAGWLGGAIYGLLYAPLVITGLH
HMFLAVDFQLMGSSLGGTYLWPIVAISNICQGSAAFGAWFVYKRRKMVKEEGLALTSGISGMLGVTEPAMFGVNLPLKYP
FIAAISTSCVLGAIVGMNNVLGKVGVGGVPAFISIQKEFWPVYLIVTAIAIVVPCILTIVMSHFSKQKAKEIVED
>Mature_474_residues
AVKREDVKAIVTAIGGKENLEAATHCVTRLRLVLKDESKVDKDALSNKALVKGQFKADHQYQIVIGPGTVDEVYKQFIDE
TGAQEASKDEAKQAAAQKGNPVQRLIKLLGDIFIPILPAIVTAGLLMGINNLLTMKGLFGPKALIEMYPQIADISNIINV
IASTAFIFLPALIGWSSMRVFGGSPILGLVLGLILMHPQLVSQYDLAKGNIPTWNLFGLEIKQLNYQGQVLPVLIAAYVL
AKIEKGLNKVVHDSIKMLVVGPVALLVTGFLAFIIIGPVALLIGTGITSGVTFIFQHAGWLGGAIYGLLYAPLVITGLHH
MFLAVDFQLMGSSLGGTYLWPIVAISNICQGSAAFGAWFVYKRRKMVKEEGLALTSGISGMLGVTEPAMFGVNLPLKYPF
IAAISTSCVLGAIVGMNNVLGKVGVGGVPAFISIQKEFWPVYLIVTAIAIVVPCILTIVMSHFSKQKAKEIVED

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI2367362, Length=443, Percent_Identity=36.568848758465, Blast_Score=301, Evalue=5e-83,
Organism=Escherichia coli, GI1790159, Length=478, Percent_Identity=26.5690376569038, Blast_Score=165, Evalue=6e-42,
Organism=Escherichia coli, GI48994906, Length=466, Percent_Identity=27.0386266094421, Blast_Score=153, Evalue=3e-38,
Organism=Escherichia coli, GI1788769, Length=464, Percent_Identity=28.448275862069, Blast_Score=150, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011296 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 50906; Mature: 50775

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVKREDVKAIVTAIGGKENLEAATHCVTRLRLVLKDESKVDKDALSNKALVKGQFKADH
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEEECCCCCCC
QYQIVIGPGTVDEVYKQFIDETGAQEASKDEAKQAAAQKGNPVQRLIKLLGDIFIPILPA
EEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
IVTAGLLMGINNLLTMKGLFGPKALIEMYPQIADISNIINVIASTAFIFLPALIGWSSMR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
VFGGSPILGLVLGLILMHPQLVSQYDLAKGNIPTWNLFGLEIKQLNYQGQVLPVLIAAYV
HCCCCCHHHHHHHHHHHCHHHHHHHHCCCCCCCCEEEECEEEEECCCCCCHHHHHHHHHH
LAKIEKGLNKVVHDSIKMLVVGPVALLVTGFLAFIIIGPVALLIGTGITSGVTFIFQHAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
WLGGAIYGLLYAPLVITGLHHMFLAVDFQLMGSSLGGTYLWPIVAISNICQGSAAFGAWF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHH
VYKRRKMVKEEGLALTSGISGMLGVTEPAMFGVNLPLKYPFIAAISTSCVLGAIVGMNNV
HHHHHHHHHHCCCCHHCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LGKVGVGGVPAFISIQKEFWPVYLIVTAIAIVVPCILTIVMSHFSKQKAKEIVED
HHHCCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AVKREDVKAIVTAIGGKENLEAATHCVTRLRLVLKDESKVDKDALSNKALVKGQFKADH
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEEECCCCCCC
QYQIVIGPGTVDEVYKQFIDETGAQEASKDEAKQAAAQKGNPVQRLIKLLGDIFIPILPA
EEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
IVTAGLLMGINNLLTMKGLFGPKALIEMYPQIADISNIINVIASTAFIFLPALIGWSSMR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
VFGGSPILGLVLGLILMHPQLVSQYDLAKGNIPTWNLFGLEIKQLNYQGQVLPVLIAAYV
HCCCCCHHHHHHHHHHHCHHHHHHHHCCCCCCCCEEEECEEEEECCCCCCHHHHHHHHHH
LAKIEKGLNKVVHDSIKMLVVGPVALLVTGFLAFIIIGPVALLIGTGITSGVTFIFQHAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
WLGGAIYGLLYAPLVITGLHHMFLAVDFQLMGSSLGGTYLWPIVAISNICQGSAAFGAWF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHH
VYKRRKMVKEEGLALTSGISGMLGVTEPAMFGVNLPLKYPFIAAISTSCVLGAIVGMNNV
HHHHHHHHHHCCCCHHCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LGKVGVGGVPAFISIQKEFWPVYLIVTAIAIVVPCILTIVMSHFSKQKAKEIVED
HHHCCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8917076; 8969503; 9272861; 9384377; 7651129 [H]