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The map label for this gene is ptsG [H]

Identifier: 82749970

GI number: 82749970

Start: 253574

End: 254365

Strand: Direct

Name: ptsG [H]

Synonym: SAB0204

Alternate gene names: 82749970

Gene position: 253574-254365 (Clockwise)

Preceding gene: 82749968

Following gene: 82749971

Centisome position: 9.25

GC content: 34.85

Gene sequence:

>792_bases
ATGAGTAATAAATATAAAGACCAAGCCCAAGACATTCTTATAGCTGTGGGTGGTGTCGAAAACATTGTTGATGTAACGTA
TGACACGAAGTGCATTACAATTCATATGCAACATACAATTCCTTCTACAGCAAATGAAGTGAAACAAATAGTTGATGTGA
CATCTGTAGCAGAAAATGATGTGCAGTTAGTCATAAAATTAAACGGAAATGTCGATGAAGTGTATCAGCAATTACAGCGA
TTAATTAAGAATACTAATGTTGAAAAGGATGCGAATACTGACAATATTAATAGCCAAGATACAAGTTATACACCTCAAGT
AAAAGTAACAACACCAATTTTAGTGAAAGCACCAATCGCTGGTCGTCGTATTTTACTTAAAGAAGTAAGAGATTCAATTT
TTAGAGAGAAAATGGTAGGCGAAGGCTTGGCAATCAAAGCTCATGAAGAATCCAAAGTAATCGCACCGTTCAATGGCTTA
GTATCTATGATTGTACCAACTAAGCATGCAGTTGGTATTCAATCAGAAGACGGTGTGGACATAGTCATTCATATTGGTGT
GAATACAGTTGACTTGGAAGGTAAAGGATTCAAGTGCTTTGTAAAGCAAAATGATCGTGTTGAAGCAGGGCAAACGTTGT
TACAATTCGATCAACAATATATTCAGGAACAAGGTTATAACTCAGACGTTATTGTCGTTATTAGCAACTCTGCCGATTTA
GGAAAAGTAGAACTGACAATGAATGAAATCATTACGACTGAAGATGTTATTTTTAAAATATTTAAAAACTAG

Upstream 100 bases:

>100_bases
TTATAATTGTATCGGCTTTTACAAATTGAACCGGTACAATTATAATTAGAGATAAGTAAATACATTTTCATTCTACTATC
AAGTTGAGGGGGTAATATTT

Downstream 100 bases:

>100_bases
GAGTGTGTTGTAATAATCACAAAATTACCGCAAAATTTTATGTGGGGTGGCGCTCTTGCCGCAAATCAATTTGAAGGTGG
ATATGATAAAGGTGGCAAAG

Product: PTS system transport protein

Products: NA

Alternate protein names: EIICBA-Glc; EII-Glc; EIICBA-Glc 1; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MSNKYKDQAQDILIAVGGVENIVDVTYDTKCITIHMQHTIPSTANEVKQIVDVTSVAENDVQLVIKLNGNVDEVYQQLQR
LIKNTNVEKDANTDNINSQDTSYTPQVKVTTPILVKAPIAGRRILLKEVRDSIFREKMVGEGLAIKAHEESKVIAPFNGL
VSMIVPTKHAVGIQSEDGVDIVIHIGVNTVDLEGKGFKCFVKQNDRVEAGQTLLQFDQQYIQEQGYNSDVIVVISNSADL
GKVELTMNEIITTEDVIFKIFKN

Sequences:

>Translated_263_residues
MSNKYKDQAQDILIAVGGVENIVDVTYDTKCITIHMQHTIPSTANEVKQIVDVTSVAENDVQLVIKLNGNVDEVYQQLQR
LIKNTNVEKDANTDNINSQDTSYTPQVKVTTPILVKAPIAGRRILLKEVRDSIFREKMVGEGLAIKAHEESKVIAPFNGL
VSMIVPTKHAVGIQSEDGVDIVIHIGVNTVDLEGKGFKCFVKQNDRVEAGQTLLQFDQQYIQEQGYNSDVIVVISNSADL
GKVELTMNEIITTEDVIFKIFKN
>Mature_262_residues
SNKYKDQAQDILIAVGGVENIVDVTYDTKCITIHMQHTIPSTANEVKQIVDVTSVAENDVQLVIKLNGNVDEVYQQLQRL
IKNTNVEKDANTDNINSQDTSYTPQVKVTTPILVKAPIAGRRILLKEVRDSIFREKMVGEGLAIKAHEESKVIAPFNGLV
SMIVPTKHAVGIQSEDGVDIVIHIGVNTVDLEGKGFKCFVKQNDRVEAGQTLLQFDQQYIQEQGYNSDVIVVISNSADLG
KVELTMNEIITTEDVIFKIFKN

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG2190

COG function: function code G; Phosphotransferase system IIA components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788757, Length=129, Percent_Identity=38.7596899224806, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1790159, Length=126, Percent_Identity=38.0952380952381, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1786894, Length=124, Percent_Identity=38.7096774193548, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: 3540 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 140 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 29183; Mature: 29051

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS51098 PTS_EIIB_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKYKDQAQDILIAVGGVENIVDVTYDTKCITIHMQHTIPSTANEVKQIVDVTSVAEND
CCCCHHCCCCEEEEEECCCCCEEEEEECCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCC
VQLVIKLNGNVDEVYQQLQRLIKNTNVEKDANTDNINSQDTSYTPQVKVTTPILVKAPIA
EEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCEEEECCCC
GRRILLKEVRDSIFREKMVGEGLAIKAHEESKVIAPFNGLVSMIVPTKHAVGIQSEDGVD
CHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEECHHHHHHHHCCCCHHCCCCCCCCCE
IVIHIGVNTVDLEGKGFKCFVKQNDRVEAGQTLLQFDQQYIQEQGYNSDVIVVISNSADL
EEEEECCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCC
GKVELTMNEIITTEDVIFKIFKN
CEEEEEHHHHCCHHHHHHHHHCC
>Mature Secondary Structure 
SNKYKDQAQDILIAVGGVENIVDVTYDTKCITIHMQHTIPSTANEVKQIVDVTSVAEND
CCCHHCCCCEEEEEECCCCCEEEEEECCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCC
VQLVIKLNGNVDEVYQQLQRLIKNTNVEKDANTDNINSQDTSYTPQVKVTTPILVKAPIA
EEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCEEEECCCC
GRRILLKEVRDSIFREKMVGEGLAIKAHEESKVIAPFNGLVSMIVPTKHAVGIQSEDGVD
CHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEECHHHHHHHHCCCCHHCCCCCCCCCE
IVIHIGVNTVDLEGKGFKCFVKQNDRVEAGQTLLQFDQQYIQEQGYNSDVIVVISNSADL
EEEEECCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCC
GKVELTMNEIITTEDVIFKIFKN
CEEEEEHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8602153; 10974121 [H]