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The map label for this gene is bglA

Identifier: 82749971

GI number: 82749971

Start: 254405

End: 255817

Strand: Direct

Name: bglA

Synonym: SAB0205

Alternate gene names: 82749971

Gene position: 254405-255817 (Clockwise)

Preceding gene: 82749970

Following gene: 82749972

Centisome position: 9.28

GC content: 36.52

Gene sequence:

>1413_bases
ATGTGGGGTGGCGCTCTTGCCGCAAATCAATTTGAAGGTGGATATGATAAAGGTGGCAAAGGATTAAGTGTAATTGATGT
TATGACGAGTGGTGCACATGGCAAAGCACGTCAGATTACAGAATCTATAGACCCCAATCACTATTATCCAAATCATGAAG
GTATTGATTTTTATCATCGTTATAAGGAAGATATTGCCTTGTTTAAAGAAATGGGATTGAAATGTTTACGTACGTCGATT
GCGTGGACACGTATCTTTCCAAATGGGGATGAAGATGTGCCAAATGAAGAAGGACTCGCCTTTTATGATCGTATCTTTGA
TGAATTAATTGCACAAGGTATTGAACCTGTTGTGACTTTATCACATTTTGAGATGCCACTTCATTTAGCGAAACATTATG
GTGGATTTAGAAATAGAGAAGTTGTCGATTATTTTGTGCATTTTGCGCGTGTTGTATTTGAAAGATATAAAGATAAAGTG
ACATATTGGATGACGTTTAATGAAATTAATAATCAGATGGACACATCAAATCCTATCTTTTTATGGACGAATTCTGGGGT
AGCATTAACAGAAAATGATAATCCCGAAGAAGTCTTGTATCAAGTAGCACATCATGAACTTTTAGCCAGTGCTTTAGCGG
TTCGTCTTGGTAAAGAGATTAATCCGAAATTTAAGATTGGAACAATGATTTCACATGTACCCATTTATCCATATTCGTGT
CATCCTAAAGATATGATGGAAGCACAAATTGCTAATCGCTTACGCTTCTTTTTCCCGGATGTTCAAGTAAGAGGTTATTA
TCCAAGCTATGCTAAAAAAATGTTGGCACGAAAAGGATATGATTTTGGATGGCAAGAAGGGGACGACAGTATTTTACAGC
AGGGCACGGTTGATTATATTGCCTTTAGTTATTACATGTCTACGGCTGTAAAACATGATGTTGATACTACAGTTGAAAAC
AACATCGTCAACGGTGGTTTGAATCATTCTGTGGAGAATCCGCATATCGCAACGAGTGATTGGGGTTGGGCGATTGATCC
AGATGGCTTAAGATATACAATGAATGTGTTATATGATCGTTATCAGTTGCCACTTTTTATTGTGAAAAATGGTTTTGGTG
CAGTTGATGAAGTGGTAGATGGACATATTCATGATGATTATCGCATTGAATATTTAAAAGCACATATTACAGCAGCGATA
GAAGCAGTTGATCAAGATGGTGTAGATTTAATCGGTTATACGCCATGGGGAATCATTGATATTGTTTCATTTACAACTGG
TGAAATGAAGAAACGCTATGGTTTAATATATGTTGATCGAGATAATGATGGTCATGGCACGATGGAACGCTTGAAAAAAG
ATTCTTTCTATTGGTATCAACAAGTGATAGCATCAAATGGAGATAAATTATAA

Upstream 100 bases:

>100_bases
ACTGACAATGAATGAAATCATTACGACTGAAGATGTTATTTTTAAAATATTTAAAAACTAGGAGTGTGTTGTAATAATCA
CAAAATTACCGCAAAATTTT

Downstream 100 bases:

>100_bases
AGGTATATTATAAGTATTTTAGGGTTAGATCCCGAGACATAAATTAATGTCTCAGGCCCTACAGTGTTATATTGGCGGGG
GCCCCCAACACAGAAGTTGG

Product: 6-phospho-beta-glucosidase

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MWGGALAANQFEGGYDKGGKGLSVIDVMTSGAHGKARQITESIDPNHYYPNHEGIDFYHRYKEDIALFKEMGLKCLRTSI
AWTRIFPNGDEDVPNEEGLAFYDRIFDELIAQGIEPVVTLSHFEMPLHLAKHYGGFRNREVVDYFVHFARVVFERYKDKV
TYWMTFNEINNQMDTSNPIFLWTNSGVALTENDNPEEVLYQVAHHELLASALAVRLGKEINPKFKIGTMISHVPIYPYSC
HPKDMMEAQIANRLRFFFPDVQVRGYYPSYAKKMLARKGYDFGWQEGDDSILQQGTVDYIAFSYYMSTAVKHDVDTTVEN
NIVNGGLNHSVENPHIATSDWGWAIDPDGLRYTMNVLYDRYQLPLFIVKNGFGAVDEVVDGHIHDDYRIEYLKAHITAAI
EAVDQDGVDLIGYTPWGIIDIVSFTTGEMKKRYGLIYVDRDNDGHGTMERLKKDSFYWYQQVIASNGDKL

Sequences:

>Translated_470_residues
MWGGALAANQFEGGYDKGGKGLSVIDVMTSGAHGKARQITESIDPNHYYPNHEGIDFYHRYKEDIALFKEMGLKCLRTSI
AWTRIFPNGDEDVPNEEGLAFYDRIFDELIAQGIEPVVTLSHFEMPLHLAKHYGGFRNREVVDYFVHFARVVFERYKDKV
TYWMTFNEINNQMDTSNPIFLWTNSGVALTENDNPEEVLYQVAHHELLASALAVRLGKEINPKFKIGTMISHVPIYPYSC
HPKDMMEAQIANRLRFFFPDVQVRGYYPSYAKKMLARKGYDFGWQEGDDSILQQGTVDYIAFSYYMSTAVKHDVDTTVEN
NIVNGGLNHSVENPHIATSDWGWAIDPDGLRYTMNVLYDRYQLPLFIVKNGFGAVDEVVDGHIHDDYRIEYLKAHITAAI
EAVDQDGVDLIGYTPWGIIDIVSFTTGEMKKRYGLIYVDRDNDGHGTMERLKKDSFYWYQQVIASNGDKL
>Mature_470_residues
MWGGALAANQFEGGYDKGGKGLSVIDVMTSGAHGKARQITESIDPNHYYPNHEGIDFYHRYKEDIALFKEMGLKCLRTSI
AWTRIFPNGDEDVPNEEGLAFYDRIFDELIAQGIEPVVTLSHFEMPLHLAKHYGGFRNREVVDYFVHFARVVFERYKDKV
TYWMTFNEINNQMDTSNPIFLWTNSGVALTENDNPEEVLYQVAHHELLASALAVRLGKEINPKFKIGTMISHVPIYPYSC
HPKDMMEAQIANRLRFFFPDVQVRGYYPSYAKKMLARKGYDFGWQEGDDSILQQGTVDYIAFSYYMSTAVKHDVDTTVEN
NIVNGGLNHSVENPHIATSDWGWAIDPDGLRYTMNVLYDRYQLPLFIVKNGFGAVDEVVDGHIHDDYRIEYLKAHITAAI
EAVDQDGVDLIGYTPWGIIDIVSFTTGEMKKRYGLIYVDRDNDGHGTMERLKKDSFYWYQQVIASNGDKL

Specific function: Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. Bgl

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=488, Percent_Identity=27.6639344262295, Blast_Score=158, Evalue=9e-39,
Organism=Homo sapiens, GI13273313, Length=483, Percent_Identity=25.6728778467909, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI110681710, Length=505, Percent_Identity=26.3366336633663, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI24497614, Length=488, Percent_Identity=28.8934426229508, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI28376633, Length=484, Percent_Identity=26.2396694214876, Blast_Score=131, Evalue=1e-30,
Organism=Escherichia coli, GI2367174, Length=471, Percent_Identity=60.5095541401274, Blast_Score=602, Evalue=1e-173,
Organism=Escherichia coli, GI1789070, Length=475, Percent_Identity=49.0526315789474, Blast_Score=491, Evalue=1e-140,
Organism=Escherichia coli, GI2367270, Length=476, Percent_Identity=50.2100840336134, Blast_Score=455, Evalue=1e-129,
Organism=Caenorhabditis elegans, GI17552856, Length=483, Percent_Identity=28.9855072463768, Blast_Score=158, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17539390, Length=492, Percent_Identity=28.0487804878049, Blast_Score=148, Evalue=5e-36,
Organism=Drosophila melanogaster, GI21356577, Length=463, Percent_Identity=25.7019438444924, Blast_Score=125, Evalue=8e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 53828; Mature: 53828

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWGGALAANQFEGGYDKGGKGLSVIDVMTSGAHGKARQITESIDPNHYYPNHEGIDFYHR
CCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCHHHHH
YKEDIALFKEMGLKCLRTSIAWTRIFPNGDEDVPNEEGLAFYDRIFDELIAQGIEPVVTL
HHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEH
SHFEMPLHLAKHYGGFRNREVVDYFVHFARVVFERYKDKVTYWMTFNEINNQMDTSNPIF
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHCCCCCCCCCEE
LWTNSGVALTENDNPEEVLYQVAHHELLASALAVRLGKEINPKFKIGTMISHVPIYPYSC
EEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECHHHHCCCCCCCCC
HPKDMMEAQIANRLRFFFPDVQVRGYYPSYAKKMLARKGYDFGWQEGDDSILQQGTVDYI
CHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHHHCCCHHHH
AFSYYMSTAVKHDVDTTVENNIVNGGLNHSVENPHIATSDWGWAIDPDGLRYTMNVLYDR
HHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCEEEECCCCCEECCCCHHHHHHHHHHH
YQLPLFIVKNGFGAVDEVVDGHIHDDYRIEYLKAHITAAIEAVDQDGVDLIGYTPWGIID
HCCCEEEEECCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHH
IVSFTTGEMKKRYGLIYVDRDNDGHGTMERLKKDSFYWYQQVIASNGDKL
HHHCCCHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MWGGALAANQFEGGYDKGGKGLSVIDVMTSGAHGKARQITESIDPNHYYPNHEGIDFYHR
CCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCHHHHH
YKEDIALFKEMGLKCLRTSIAWTRIFPNGDEDVPNEEGLAFYDRIFDELIAQGIEPVVTL
HHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEH
SHFEMPLHLAKHYGGFRNREVVDYFVHFARVVFERYKDKVTYWMTFNEINNQMDTSNPIF
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHCCCCCCCCCEE
LWTNSGVALTENDNPEEVLYQVAHHELLASALAVRLGKEINPKFKIGTMISHVPIYPYSC
EEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECHHHHCCCCCCCCC
HPKDMMEAQIANRLRFFFPDVQVRGYYPSYAKKMLARKGYDFGWQEGDDSILQQGTVDYI
CHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHHHCCCHHHH
AFSYYMSTAVKHDVDTTVENNIVNGGLNHSVENPHIATSDWGWAIDPDGLRYTMNVLYDR
HHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCEEEECCCCCEECCCCHHHHHHHHHHH
YQLPLFIVKNGFGAVDEVVDGHIHDDYRIEYLKAHITAAIEAVDQDGVDLIGYTPWGIID
HCCCEEEEECCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHH
IVSFTTGEMKKRYGLIYVDRDNDGHGTMERLKKDSFYWYQQVIASNGDKL
HHHCCCHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8125345; 9384377 [H]