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The map label for this gene is yuxJ [H]

Identifier: 82749833

GI number: 82749833

Start: 75522

End: 76778

Strand: Direct

Name: yuxJ [H]

Synonym: SAB0058

Alternate gene names: 82749833

Gene position: 75522-76778 (Clockwise)

Preceding gene: 82749832

Following gene: 82749834

Centisome position: 2.75

GC content: 38.58

Gene sequence:

>1257_bases
ATGATTAATCAGACTATATGGCGCAGTAACTTTCGCATTTTATGGCTCAGTCAGTTTATAGCGATTGCTGGACTGACAGT
ACTTGTGCCATTATTGCCAATTTATATGGCATCACTACAAAATCTATCAGTCGTAGAAATACAGTTGTGGAGTGGTATAG
CGATTGCTGCTCCAGCTGTAACGACGATGATAGCTTCGCCGATATGGGGGAAGCTAGGTGATAAGATCAGCCGAAAATGG
ATGGTGTTAAGAGCGTTACTTGGTTTGGCGGTATGCTTATTTTTAATGGCATTGTGTACTACACCATTACAGTTTGTACT
TGTGAGGTTATTGCAGGGACTATTTGGTGGTGTTGTTGATGCATCAAGTGCGTTTGCGAGTGCAGAGGCGCCAGCTGAAG
ATCGTGGAAAGGTATTAGGAAGACTGCAAAGTTCAGTCAGCGCAGGGTCTCTTGTGGGACCATTAATTGGCAGTGTTACA
GCTTCGATATTAGGTTTTAGTGCGTTACTGATGAGTATTGCCGTTATTACTTTTATTGTCTGTATTTTCGGTGCATTAAA
ATTGATTGAAACGACACATATGCCAAAATCGCAAATACCAAATATTAATAAAGGTATTCGCCGTTCATTTCAATGTCTAC
TATGCACACAACAAACGTGTCGATTTATTATCGTTGGCGTTTTAGCAAACTTTGCTATGTATGGCATGCTAACTGCATTA
TCACCACTTGCTTCATCAGTGAATCATACAGCGATAGATGACCGTAGTGTGATTGGATTTTTACAGTCCGCATTTTGGAC
GGCTTCGATATTAAGCGCGCCTTTATGGGGTCGCTTTAATGATAAATCATATGTTAAATCAGTATATATATTTGCCACGA
TTGCATGTGGTTGTAGTGCGATACTGCAAGGTTTAGCGACGAATATAGAGTTTTTAATGGCTGCAAGAATACTTCAAGGA
TTAACATATAGTGCATTGATTCAAAGTGTCATGTTTGTTGTTGTAAATGCTTGTCATCAGCAACTTAAAGGCACATTTGT
TGGAACGACGAACAGTATGTTAGTTATTGGTCAAATTATTGGTAGTCTTAGTGGCGCTGCCATTACAAGTTATACTACAC
CAGCTACTACGTTTATCGTTATGGGCATAGTATTTGCTGTAAGTAGTTTATTTTTAATTTGTTCAACCATTACTAATCAA
ATCAACGATCACACATTAATGAAATTATGGGAGTTGAAACAAAAAAGTGCAAAATAA

Upstream 100 bases:

>100_bases
CCATTTAAACAAATTTTATTACCATTGCTATATCAACGTGATAGTGGTGGAGGTAGTATGCCTTCAGGTTTAACTACCGT
ACCAAATCCAATGGTGACAT

Downstream 100 bases:

>100_bases
AGAATTAATACAACATGCAGCGTATGCGGCTATCGAACGCATTTTAAATGAATATTTTAGAAAAGAAAATTTATATCAAG
TACCACCTCAAAATCATCAA

Product: membrane transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: ORF1 [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MINQTIWRSNFRILWLSQFIAIAGLTVLVPLLPIYMASLQNLSVVEIQLWSGIAIAAPAVTTMIASPIWGKLGDKISRKW
MVLRALLGLAVCLFLMALCTTPLQFVLVRLLQGLFGGVVDASSAFASAEAPAEDRGKVLGRLQSSVSAGSLVGPLIGSVT
ASILGFSALLMSIAVITFIVCIFGALKLIETTHMPKSQIPNINKGIRRSFQCLLCTQQTCRFIIVGVLANFAMYGMLTAL
SPLASSVNHTAIDDRSVIGFLQSAFWTASILSAPLWGRFNDKSYVKSVYIFATIACGCSAILQGLATNIEFLMAARILQG
LTYSALIQSVMFVVVNACHQQLKGTFVGTTNSMLVIGQIIGSLSGAAITSYTTPATTFIVMGIVFAVSSLFLICSTITNQ
INDHTLMKLWELKQKSAK

Sequences:

>Translated_418_residues
MINQTIWRSNFRILWLSQFIAIAGLTVLVPLLPIYMASLQNLSVVEIQLWSGIAIAAPAVTTMIASPIWGKLGDKISRKW
MVLRALLGLAVCLFLMALCTTPLQFVLVRLLQGLFGGVVDASSAFASAEAPAEDRGKVLGRLQSSVSAGSLVGPLIGSVT
ASILGFSALLMSIAVITFIVCIFGALKLIETTHMPKSQIPNINKGIRRSFQCLLCTQQTCRFIIVGVLANFAMYGMLTAL
SPLASSVNHTAIDDRSVIGFLQSAFWTASILSAPLWGRFNDKSYVKSVYIFATIACGCSAILQGLATNIEFLMAARILQG
LTYSALIQSVMFVVVNACHQQLKGTFVGTTNSMLVIGQIIGSLSGAAITSYTTPATTFIVMGIVFAVSSLFLICSTITNQ
INDHTLMKLWELKQKSAK
>Mature_418_residues
MINQTIWRSNFRILWLSQFIAIAGLTVLVPLLPIYMASLQNLSVVEIQLWSGIAIAAPAVTTMIASPIWGKLGDKISRKW
MVLRALLGLAVCLFLMALCTTPLQFVLVRLLQGLFGGVVDASSAFASAEAPAEDRGKVLGRLQSSVSAGSLVGPLIGSVT
ASILGFSALLMSIAVITFIVCIFGALKLIETTHMPKSQIPNINKGIRRSFQCLLCTQQTCRFIIVGVLANFAMYGMLTAL
SPLASSVNHTAIDDRSVIGFLQSAFWTASILSAPLWGRFNDKSYVKSVYIFATIACGCSAILQGLATNIEFLMAARILQG
LTYSALIQSVMFVVVNACHQQLKGTFVGTTNSMLVIGQIIGSLSGAAITSYTTPATTFIVMGIVFAVSSLFLICSTITNQ
INDHTLMKLWELKQKSAK

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787291, Length=383, Percent_Identity=27.9373368146214, Blast_Score=113, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001958 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44920; Mature: 44920

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINQTIWRSNFRILWLSQFIAIAGLTVLVPLLPIYMASLQNLSVVEIQLWSGIAIAAPAV
CCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHH
TTMIASPIWGKLGDKISRKWMVLRALLGLAVCLFLMALCTTPLQFVLVRLLQGLFGGVVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
ASSAFASAEAPAEDRGKVLGRLQSSVSAGSLVGPLIGSVTASILGFSALLMSIAVITFIV
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CIFGALKLIETTHMPKSQIPNINKGIRRSFQCLLCTQQTCRFIIVGVLANFAMYGMLTAL
HHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SPLASSVNHTAIDDRSVIGFLQSAFWTASILSAPLWGRFNDKSYVKSVYIFATIACGCSA
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ILQGLATNIEFLMAARILQGLTYSALIQSVMFVVVNACHQQLKGTFVGTTNSMLVIGQII
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
GSLSGAAITSYTTPATTFIVMGIVFAVSSLFLICSTITNQINDHTLMKLWELKQKSAK
HCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MINQTIWRSNFRILWLSQFIAIAGLTVLVPLLPIYMASLQNLSVVEIQLWSGIAIAAPAV
CCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHH
TTMIASPIWGKLGDKISRKWMVLRALLGLAVCLFLMALCTTPLQFVLVRLLQGLFGGVVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
ASSAFASAEAPAEDRGKVLGRLQSSVSAGSLVGPLIGSVTASILGFSALLMSIAVITFIV
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CIFGALKLIETTHMPKSQIPNINKGIRRSFQCLLCTQQTCRFIIVGVLANFAMYGMLTAL
HHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SPLASSVNHTAIDDRSVIGFLQSAFWTASILSAPLWGRFNDKSYVKSVYIFATIACGCSA
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ILQGLATNIEFLMAARILQGLTYSALIQSVMFVVVNACHQQLKGTFVGTTNSMLVIGQII
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
GSLSGAAITSYTTPATTFIVMGIVFAVSSLFLICSTITNQINDHTLMKLWELKQKSAK
HCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377; 10568751; 7961491 [H]