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The map label for this gene is plc

Identifier: 82749815

GI number: 82749815

Start: 48181

End: 49167

Strand: Direct

Name: plc

Synonym: SAB0038

Alternate gene names: 82749815

Gene position: 48181-49167 (Clockwise)

Preceding gene: 82749814

Following gene: 82749816

Centisome position: 1.76

GC content: 33.64

Gene sequence:

>987_bases
ATGAAAAAGTGTATTAAGACTTTGTTTTTAAGTATCATTTTAGTAGTGATGAGTGGTTTATATCATTCAGCACATGCGTC
AAATTCGTTGAGTAAAAGTCCAGAAAATTGGATGAGTAAACTTGATGAAAGCAAACATTTAACTGAGATTAATATGCCAG
GCTCACATGATAGTGGCTCATTCACTTTAACTGATCCGGTAAAATCAGTTTGGGCAAAGACTCAAGATAAAGATTACCTT
ACTCAAATGAAGTCAGGAGTCAGATTTTTTGATATTAGAGGTAGAGCAAGTGCTGATAATATGATTTCAGTTCATCACGG
CATGGTTTATCTGCATCATGAACTAGGTAAATTTTTAGATGATGCTAAATATTACTTGAGTGCTTATCCAAATGAAACAA
TAGTGATGTCTATGAAAAAGGACTACGATAGCGACTCTAAAGTTACGAAGACATTTGAAGAAATTTTCAGAGAATCTTAT
TTTAATAACCCGCAATATCAAAATCTTTTTTACACAGGAAGTAATGCGAATCCTACTTTAAAAGAAACGAAAGGTAAAAT
TGTCCTATTCAATAGAATGGGGGGTACATACATAAAGAGTGGTTATGGTGCTGACACGTCAGGTATTCAATGGGCAGACA
ACGCGACATTTGAAACGAAAATTAATAATGGTAACTTAAATTTACAGGTACAAGATGAGTATAAAGATTATTACGATAAG
AAAGTAGAAGCTGTTAAAAATTTATTGGCTAAAGCAAAAACGGATAGTAACAAAGACAATCTATATGTGAATTTCTTGAG
TGTGGCGTCTGGAGGCAGCGCATTTAATAGTACTTATAACTATGCATCACATATAAATCCTGAAATTGCAAAAACGATTA
AAGCAAATGGAAAAGCTAGAACGGGTTGGCTGATTGTTGACTATGCAGGGTATCCGTGGCCTGGATATGATGATATCGTA
AGCGAAATTATAGATAGTAATAAATAA

Upstream 100 bases:

>100_bases
TTATTGAAACATCAATTAAATAAGTTTTAAAATTTTACACATATTTTTATTTAAAAAAGATGTATAATTAATGTATTAAA
TATAGAAAGAAGTTGATATT

Downstream 100 bases:

>100_bases
GGATTCAATAATGATATTAAGACGAGTATGAAAATAGTTAGATTCTAATTATTTTCATACTCGTTTTTATTTTGAAAATA
AGTAATGATTCAACAATATT

Product: 1-phosphatidylinositol phosphodiesterase

Products: NA

Alternate protein names: Phosphatidylinositol diacylglycerol-lyase; Phosphatidylinositol-specific phospholipase C; PI-PLC [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MKKCIKTLFLSIILVVMSGLYHSAHASNSLSKSPENWMSKLDESKHLTEINMPGSHDSGSFTLTDPVKSVWAKTQDKDYL
TQMKSGVRFFDIRGRASADNMISVHHGMVYLHHELGKFLDDAKYYLSAYPNETIVMSMKKDYDSDSKVTKTFEEIFRESY
FNNPQYQNLFYTGSNANPTLKETKGKIVLFNRMGGTYIKSGYGADTSGIQWADNATFETKINNGNLNLQVQDEYKDYYDK
KVEAVKNLLAKAKTDSNKDNLYVNFLSVASGGSAFNSTYNYASHINPEIAKTIKANGKARTGWLIVDYAGYPWPGYDDIV
SEIIDSNK

Sequences:

>Translated_328_residues
MKKCIKTLFLSIILVVMSGLYHSAHASNSLSKSPENWMSKLDESKHLTEINMPGSHDSGSFTLTDPVKSVWAKTQDKDYL
TQMKSGVRFFDIRGRASADNMISVHHGMVYLHHELGKFLDDAKYYLSAYPNETIVMSMKKDYDSDSKVTKTFEEIFRESY
FNNPQYQNLFYTGSNANPTLKETKGKIVLFNRMGGTYIKSGYGADTSGIQWADNATFETKINNGNLNLQVQDEYKDYYDK
KVEAVKNLLAKAKTDSNKDNLYVNFLSVASGGSAFNSTYNYASHINPEIAKTIKANGKARTGWLIVDYAGYPWPGYDDIV
SEIIDSNK
>Mature_328_residues
MKKCIKTLFLSIILVVMSGLYHSAHASNSLSKSPENWMSKLDESKHLTEINMPGSHDSGSFTLTDPVKSVWAKTQDKDYL
TQMKSGVRFFDIRGRASADNMISVHHGMVYLHHELGKFLDDAKYYLSAYPNETIVMSMKKDYDSDSKVTKTFEEIFRESY
FNNPQYQNLFYTGSNANPTLKETKGKIVLFNRMGGTYIKSGYGADTSGIQWADNATFETKINNGNLNLQVQDEYKDYYDK
KVEAVKNLLAKAKTDSNKDNLYVNFLSVASGGSAFNSTYNYASHINPEIAKTIKANGKARTGWLIVDYAGYPWPGYDDIV
SEIIDSNK

Specific function: Cleaves glycosylphosphatidylinositol (GPI) and phosphatidylinositol (PI) anchors but not PI phosphates. Potential virulence factor [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PI-PLC X-box domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017946
- InterPro:   IPR000909 [H]

Pfam domain/function: PF00388 PI-PLC-X [H]

EC number: =4.6.1.13 [H]

Molecular weight: Translated: 36993; Mature: 36993

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: PS50007 PIPLC_X_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKCIKTLFLSIILVVMSGLYHSAHASNSLSKSPENWMSKLDESKHLTEINMPGSHDSGS
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCEEECCCCCCCCCC
FTLTDPVKSVWAKTQDKDYLTQMKSGVRFFDIRGRASADNMISVHHGMVYLHHELGKFLD
EEECHHHHHHHHCCCCHHHHHHHHCCCEEEEECCCCCCCCEEEECCCEEEEHHHHHHHHH
DAKYYLSAYPNETIVMSMKKDYDSDSKVTKTFEEIFRESYFNNPQYQNLFYTGSNANPTL
HHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCH
KETKGKIVLFNRMGGTYIKSGYGADTSGIQWADNATFETKINNGNLNLQVQDEYKDYYDK
HHCCCCEEEEECCCCCEEECCCCCCCCCCEECCCCEEEEEECCCEEEEEEEHHHHHHHHH
KVEAVKNLLAKAKTDSNKDNLYVNFLSVASGGSAFNSTYNYASHINPEIAKTIKANGKAR
HHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCHHCCCCCHHHHCCHHHHHHHHCCCCCE
TGWLIVDYAGYPWPGYDDIVSEIIDSNK
ECEEEEECCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MKKCIKTLFLSIILVVMSGLYHSAHASNSLSKSPENWMSKLDESKHLTEINMPGSHDSGS
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCEEECCCCCCCCCC
FTLTDPVKSVWAKTQDKDYLTQMKSGVRFFDIRGRASADNMISVHHGMVYLHHELGKFLD
EEECHHHHHHHHCCCCHHHHHHHHCCCEEEEECCCCCCCCEEEECCCEEEEHHHHHHHHH
DAKYYLSAYPNETIVMSMKKDYDSDSKVTKTFEEIFRESYFNNPQYQNLFYTGSNANPTL
HHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCH
KETKGKIVLFNRMGGTYIKSGYGADTSGIQWADNATFETKINNGNLNLQVQDEYKDYYDK
HHCCCCEEEEECCCCCEEECCCCCCCCCCEECCCCEEEEEECCCEEEEEEEHHHHHHHHH
KVEAVKNLLAKAKTDSNKDNLYVNFLSVASGGSAFNSTYNYASHINPEIAKTIKANGKAR
HHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCHHCCCCCHHHHCCHHHHHHHHCCCCCE
TGWLIVDYAGYPWPGYDDIVSEIIDSNK
ECEEEEECCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8225585 [H]