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The map label for this gene is pqqL [C]

Identifier: 82703850

GI number: 82703850

Start: 3142054

End: 3143451

Strand: Reverse

Name: pqqL [C]

Synonym: Nmul_A2737

Alternate gene names: 82703850

Gene position: 3143451-3142054 (Counterclockwise)

Preceding gene: 82703855

Following gene: 82703849

Centisome position: 98.72

GC content: 57.15

Gene sequence:

>1398_bases
ATGACTTATCCGTGCTTTCGCTTTTTGCCGGCTTGCTTATGGGCGGCTCTCGTAATCCCCGTCTCGCTGTTCTCCTCCGC
CGCTCTTGCCAGCACGCATGAATTCACTCTGGGTAATGGCTTGCGGCTCATCGTCAAGGAAGATCATCGTTCCCCGGTCG
TCATCTCGCAAATCTGGTACAAGGCCGGGAGCATCGACGAGGTAAACGGCAGGACTGGCGTCGCCCACGTGCTTGAACAC
ATGATGTTCAAGGGCACGAAGAAAGTACCGGGCGGCGAGTTTTCCCGCCTCATCGCAGCGGCGGGGGGCCGTGAAAACGC
TTTCACGGCGCAGGATTATACGGCCTATTTTCAGCAATTGCATAAGTCCCGGCTGCCGCTGGCGATGGAACTGGAATCGG
ACAGGATGCGCAATCTGGTGCTGACAGAAGAGGAGTTTTCCAAGGAAATCAAAGTCGTGATGGAAGAACGGCGGTTACGT
ACGGACGATCAGGCGCGCTCTCTGGTCCATGAGACACTTATGGCGACCTCCTATCAGTCGCACCCTTACCGGCATCCGGT
GATAGGCTGGATGAACGATCTGCAGAACATGACTGTGGGGGACGCCCGGCAATGGTATGAACGCTGGTATGCGCCCAACA
ATGCTGTGCTTGTGGTGGTCGGGGATGTAGACCCCCGGCAGACCTTCAATCTGGCGCGAAAATACTACGGACAGATAAAG
GCGAAGCCCGTGCTGTCCCTGGACCAACGCAAGCCACAGATCGAGCCGAAGCAGCTCGGCGTCAAGCGGCTGACAGTAAA
AGCGCCCGCGCAATTGCCCTACGTTGCAATGGCTTATCATGCTATATCGCTGAGCAAGCCGGAAACGGACTGGGAGCCGT
ATGCACTCGAGATGCTGGCGGGCGTGCTCGATGGGAATGAATCGGCGCGGCTCAATAAAGCCCTGGTGCGTGAGCAGCGC
ATCGCCAGCACGGCCGGAGCCAGCTATGATTCCACCGCGCGAGGTCCCGCGGTGTTTTATCTCGATGGCACACCGAGCGA
AGGCAAAACAGTGGGTGAGGTGGAAGCGGCGTTGCGTGCCGAGATCGAAAAGCTCGTACGTGACGGCGTGACAGAGGAGG
AGCTTGCGCGCGTCAAGGCACAGGTGGTGGCGGGACACGTTTTTCAGCTCGATTCCATGTTTTTCCAGGCAATGCAGATC
GGCCAGCTCGAAAGTATAGGATTGTCCTATCGCGATGTGGACACCATATTGCGTAAATTGCAGGCTGTTACCGCCGAACA
GGTGCGCGAGGTGGCAAAAAAATACTTGAAGGACGATAATCTGACGATTGCAGTACTCGATCCGCAGCCCCTGGAACAGA
AAGCACCCGCGGCAGTACCGGCGGGTTTGCGGCATTAA

Upstream 100 bases:

>100_bases
GGTAGGCTGTCAGTATTTGAGACCTCGAAGTAAACCTCACGCAATCTTATTCTGGATTTTATTCTGTTTATCCGGATTCA
GGTATTAATTAAAAAAGAAG

Downstream 100 bases:

>100_bases
GCGGCGAGGTTGAGAGATGCTCCGTCACCTGTTTTTCCTTTTCCTGGGCTTTTATTCCCAATGGGCGTACGCCACTCTGC
CAATCCAGCACTGGCAGGCA

Product: peptidase M16-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MTYPCFRFLPACLWAALVIPVSLFSSAALASTHEFTLGNGLRLIVKEDHRSPVVISQIWYKAGSIDEVNGRTGVAHVLEH
MMFKGTKKVPGGEFSRLIAAAGGRENAFTAQDYTAYFQQLHKSRLPLAMELESDRMRNLVLTEEEFSKEIKVVMEERRLR
TDDQARSLVHETLMATSYQSHPYRHPVIGWMNDLQNMTVGDARQWYERWYAPNNAVLVVVGDVDPRQTFNLARKYYGQIK
AKPVLSLDQRKPQIEPKQLGVKRLTVKAPAQLPYVAMAYHAISLSKPETDWEPYALEMLAGVLDGNESARLNKALVREQR
IASTAGASYDSTARGPAVFYLDGTPSEGKTVGEVEAALRAEIEKLVRDGVTEEELARVKAQVVAGHVFQLDSMFFQAMQI
GQLESIGLSYRDVDTILRKLQAVTAEQVREVAKKYLKDDNLTIAVLDPQPLEQKAPAAVPAGLRH

Sequences:

>Translated_465_residues
MTYPCFRFLPACLWAALVIPVSLFSSAALASTHEFTLGNGLRLIVKEDHRSPVVISQIWYKAGSIDEVNGRTGVAHVLEH
MMFKGTKKVPGGEFSRLIAAAGGRENAFTAQDYTAYFQQLHKSRLPLAMELESDRMRNLVLTEEEFSKEIKVVMEERRLR
TDDQARSLVHETLMATSYQSHPYRHPVIGWMNDLQNMTVGDARQWYERWYAPNNAVLVVVGDVDPRQTFNLARKYYGQIK
AKPVLSLDQRKPQIEPKQLGVKRLTVKAPAQLPYVAMAYHAISLSKPETDWEPYALEMLAGVLDGNESARLNKALVREQR
IASTAGASYDSTARGPAVFYLDGTPSEGKTVGEVEAALRAEIEKLVRDGVTEEELARVKAQVVAGHVFQLDSMFFQAMQI
GQLESIGLSYRDVDTILRKLQAVTAEQVREVAKKYLKDDNLTIAVLDPQPLEQKAPAAVPAGLRH
>Mature_464_residues
TYPCFRFLPACLWAALVIPVSLFSSAALASTHEFTLGNGLRLIVKEDHRSPVVISQIWYKAGSIDEVNGRTGVAHVLEHM
MFKGTKKVPGGEFSRLIAAAGGRENAFTAQDYTAYFQQLHKSRLPLAMELESDRMRNLVLTEEEFSKEIKVVMEERRLRT
DDQARSLVHETLMATSYQSHPYRHPVIGWMNDLQNMTVGDARQWYERWYAPNNAVLVVVGDVDPRQTFNLARKYYGQIKA
KPVLSLDQRKPQIEPKQLGVKRLTVKAPAQLPYVAMAYHAISLSKPETDWEPYALEMLAGVLDGNESARLNKALVREQRI
ASTAGASYDSTARGPAVFYLDGTPSEGKTVGEVEAALRAEIEKLVRDGVTEEELARVKAQVVAGHVFQLDSMFFQAMQIG
QLESIGLSYRDVDTILRKLQAVTAEQVREVAKKYLKDDNLTIAVLDPQPLEQKAPAAVPAGLRH

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=422, Percent_Identity=25.1184834123223, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI46593007, Length=279, Percent_Identity=28.3154121863799, Blast_Score=108, Evalue=1e-23,
Organism=Escherichia coli, GI1787770, Length=215, Percent_Identity=32.093023255814, Blast_Score=99, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17553678, Length=204, Percent_Identity=29.9019607843137, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71999683, Length=225, Percent_Identity=25.7777777777778, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI72001443, Length=250, Percent_Identity=25.6, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323192, Length=426, Percent_Identity=23.2394366197183, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6323421, Length=320, Percent_Identity=22.5, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21357875, Length=434, Percent_Identity=24.8847926267281, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24646943, Length=434, Percent_Identity=24.8847926267281, Blast_Score=104, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 52011; Mature: 51880

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYPCFRFLPACLWAALVIPVSLFSSAALASTHEFTLGNGLRLIVKEDHRSPVVISQIWY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEEEECCCCCEEHHHHHH
KAGSIDEVNGRTGVAHVLEHMMFKGTKKVPGGEFSRLIAAAGGRENAFTAQDYTAYFQQL
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
HKSRLPLAMELESDRMRNLVLTEEEFSKEIKVVMEERRLRTDDQARSLVHETLMATSYQS
HHCCCCEEEEECHHHHHHEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
HPYRHPVIGWMNDLQNMTVGDARQWYERWYAPNNAVLVVVGDVDPRQTFNLARKYYGQIK
CCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCC
AKPVLSLDQRKPQIEPKQLGVKRLTVKAPAQLPYVAMAYHAISLSKPETDWEPYALEMLA
CCCCCCCCCCCCCCCHHHCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHH
GVLDGNESARLNKALVREQRIASTAGASYDSTARGPAVFYLDGTPSEGKTVGEVEAALRA
HHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHH
EIEKLVRDGVTEEELARVKAQVVAGHVFQLDSMFFQAMQIGQLESIGLSYRDVDTILRKL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHH
QAVTAEQVREVAKKYLKDDNLTIAVLDPQPLEQKAPAAVPAGLRH
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHCCCCCCCCCCCC
>Mature Secondary Structure 
TYPCFRFLPACLWAALVIPVSLFSSAALASTHEFTLGNGLRLIVKEDHRSPVVISQIWY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEEEECCCCCEEHHHHHH
KAGSIDEVNGRTGVAHVLEHMMFKGTKKVPGGEFSRLIAAAGGRENAFTAQDYTAYFQQL
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
HKSRLPLAMELESDRMRNLVLTEEEFSKEIKVVMEERRLRTDDQARSLVHETLMATSYQS
HHCCCCEEEEECHHHHHHEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
HPYRHPVIGWMNDLQNMTVGDARQWYERWYAPNNAVLVVVGDVDPRQTFNLARKYYGQIK
CCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCC
AKPVLSLDQRKPQIEPKQLGVKRLTVKAPAQLPYVAMAYHAISLSKPETDWEPYALEMLA
CCCCCCCCCCCCCCCHHHCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHH
GVLDGNESARLNKALVREQRIASTAGASYDSTARGPAVFYLDGTPSEGKTVGEVEAALRA
HHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHH
EIEKLVRDGVTEEELARVKAQVVAGHVFQLDSMFFQAMQIGQLESIGLSYRDVDTILRKL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHH
QAVTAEQVREVAKKYLKDDNLTIAVLDPQPLEQKAPAAVPAGLRH
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]