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The map label for this gene is dhaK [H]

Identifier: 82703839

GI number: 82703839

Start: 3128080

End: 3129750

Strand: Direct

Name: dhaK [H]

Synonym: Nmul_A2726

Alternate gene names: 82703839

Gene position: 3128080-3129750 (Clockwise)

Preceding gene: 82703838

Following gene: 82703840

Centisome position: 98.24

GC content: 62.06

Gene sequence:

>1671_bases
ATGTTGCGTGCGCAGCTTTTTGATCAGCAAAAATTCAGTCAGATAGGAGAAAACATGGCCCAGTTCATCAACACCAAAGA
AAACATCGTCACCGAAGCGGTCGATGCTCTGGTCGCGGCCTCTGGCGGTAAGCTGGCGCGGCTCGACGGCTATCCACATA
TACGGGTGGTCGTACGCAATGACTGGGATAAGTCCAAGGTCGCGTTGATTTCGGGAGGCGGATCGGGCCACGAACCGGCA
CATGCGGGTTTCGTCGGGAAAGGAATGCTGACGGCTGCGGTGTGCGGCGACATCTTCGCCTCCCCTACAGTCGACGCGGT
ACTGGCAGGCATCCTTGCCGTGACGGGATCGTCCGGCTGCCTGCTCATCGTCAAGAATTATACCGGTGACCGATTGAATT
TCGGGCTGGCGGCCGAACGCGCTCGCCCGTTCGGCTTGAATGTCGAGATAGTCATCGTCGGCGATGATGTGGCGTTGCCC
GGCTTGCCGCAAGCCCGCGGCGTCGCCGGCACGCTTTTCGTGCACAAGATAGCCGGCGCGTTGGCCGAGAATGGAGCCGA
CTTGGCGCATGTCGCCGCAGCCGCGCGCAAGGTGGTGTCAAAGACAAAAAGCATCGGCATCTCGCTAAACACCTGCACCA
TCCCAGGTTTGCCAAAGGAGGATCGCATCCCGCCCGGCATGGCCGAGCTTGGGCTTGGCATCCACGGTGAAGCCGGGGTT
GAGCAGGTCGAATTCAAGGACGCGACCGGAGCTGTCGCTGCCATGGTCGAGCGCCTGTCAGCTGCAATGGAAGAAAAGCC
GCATGTCGTTATGGTCAACAATCTCGGCGGCACGTCGGTCATCGAGATGTCGATCATCCTCAACGAAATCCGGCGGTCAG
CGATTGGCGAGCAGATAACCCACGTCATCGGGCCGGCGGCCATGATGACATCTCTCGATATGCATGGCTTCTCGATTTCA
GCCTATCCTGCCGACGATGCAGAGATCGCCCTTCTCAAGCAGCACACGCCGCTGGCAGCATGGCCCGGGGTCTCCCGGTT
GGGTCAGGTCGCGATTCAGGCGCTTCCGGACGGCCTGACGCCAGTCGTTCCGATGCCCTCGATGCACAGGCCGACCAGGG
AGTTCCTGATCAGGTGCTGCGAGGTTCTGATCGCCGCCGAGAACGACCTTAACGCGCTCGACGCGAAGTCAGGCGATGGC
GACACCGGCAGCACGCTAGCCGGGGCGGCACGTGCCCTGATCAGCGCCGTGGACCGATTGCCGCTTGCCGACCATACCCA
GCTCTATCGAGCCATTGGCTTGGAGCTTTCCCAAACCATGGGAGGCTCGTGCGGTGTGCTCCTCGCGATCTTCTTCGCCG
CTGCGGGCGACGCCGCCTCAAGCGGCTCGCCAATGCGCGAAGCGTTGCAGGCCGGGTTGCGGAGAATGCAGGAAATCGGC
GGGGCTCGCCCGGGTGACCGCACCATGGTCGATGCCCTTGCGCCGGCCCTTGATGTCCTGGAAGAGAGCCTGTCCGAGGC
GGCGAAAGCCGCGCGTGCGGGCGCCGATCGCACTGCCCACATGAGCAAGGCGAATGCGGGTCGCGCTTCCTATGTCAATG
CCAGGCATTTGGTCGGTCACGCTGATCCAGGTGCTGAGGCGGTCGCGCGACTGTTTGAACACTTGGCCTAG

Upstream 100 bases:

>100_bases
GAGTAATAAATAAGCTTGTCAACCGCCCGTTTCTTTCAGAGACCAGCAAAACGATATCTTCCAGTGACGCGCGCGCATTT
ATACCCGGGTTGAGCAACGG

Downstream 100 bases:

>100_bases
GTTTAGATTGTAAGCATCTGTTGAATCGCCCTGATTTTTGAGCTGGATAATTTTTCCCGCGATCACAAAGAAAACTGCTT
CTCCCCTTTTGCTATTTTTA

Product: Glycerone kinase

Products: NA

Alternate protein names: DHA kinase; Glycerone kinase [H]

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MLRAQLFDQQKFSQIGENMAQFINTKENIVTEAVDALVAASGGKLARLDGYPHIRVVVRNDWDKSKVALISGGGSGHEPA
HAGFVGKGMLTAAVCGDIFASPTVDAVLAGILAVTGSSGCLLIVKNYTGDRLNFGLAAERARPFGLNVEIVIVGDDVALP
GLPQARGVAGTLFVHKIAGALAENGADLAHVAAAARKVVSKTKSIGISLNTCTIPGLPKEDRIPPGMAELGLGIHGEAGV
EQVEFKDATGAVAAMVERLSAAMEEKPHVVMVNNLGGTSVIEMSIILNEIRRSAIGEQITHVIGPAAMMTSLDMHGFSIS
AYPADDAEIALLKQHTPLAAWPGVSRLGQVAIQALPDGLTPVVPMPSMHRPTREFLIRCCEVLIAAENDLNALDAKSGDG
DTGSTLAGAARALISAVDRLPLADHTQLYRAIGLELSQTMGGSCGVLLAIFFAAAGDAASSGSPMREALQAGLRRMQEIG
GARPGDRTMVDALAPALDVLEESLSEAAKAARAGADRTAHMSKANAGRASYVNARHLVGHADPGAEAVARLFEHLA

Sequences:

>Translated_556_residues
MLRAQLFDQQKFSQIGENMAQFINTKENIVTEAVDALVAASGGKLARLDGYPHIRVVVRNDWDKSKVALISGGGSGHEPA
HAGFVGKGMLTAAVCGDIFASPTVDAVLAGILAVTGSSGCLLIVKNYTGDRLNFGLAAERARPFGLNVEIVIVGDDVALP
GLPQARGVAGTLFVHKIAGALAENGADLAHVAAAARKVVSKTKSIGISLNTCTIPGLPKEDRIPPGMAELGLGIHGEAGV
EQVEFKDATGAVAAMVERLSAAMEEKPHVVMVNNLGGTSVIEMSIILNEIRRSAIGEQITHVIGPAAMMTSLDMHGFSIS
AYPADDAEIALLKQHTPLAAWPGVSRLGQVAIQALPDGLTPVVPMPSMHRPTREFLIRCCEVLIAAENDLNALDAKSGDG
DTGSTLAGAARALISAVDRLPLADHTQLYRAIGLELSQTMGGSCGVLLAIFFAAAGDAASSGSPMREALQAGLRRMQEIG
GARPGDRTMVDALAPALDVLEESLSEAAKAARAGADRTAHMSKANAGRASYVNARHLVGHADPGAEAVARLFEHLA
>Mature_556_residues
MLRAQLFDQQKFSQIGENMAQFINTKENIVTEAVDALVAASGGKLARLDGYPHIRVVVRNDWDKSKVALISGGGSGHEPA
HAGFVGKGMLTAAVCGDIFASPTVDAVLAGILAVTGSSGCLLIVKNYTGDRLNFGLAAERARPFGLNVEIVIVGDDVALP
GLPQARGVAGTLFVHKIAGALAENGADLAHVAAAARKVVSKTKSIGISLNTCTIPGLPKEDRIPPGMAELGLGIHGEAGV
EQVEFKDATGAVAAMVERLSAAMEEKPHVVMVNNLGGTSVIEMSIILNEIRRSAIGEQITHVIGPAAMMTSLDMHGFSIS
AYPADDAEIALLKQHTPLAAWPGVSRLGQVAIQALPDGLTPVVPMPSMHRPTREFLIRCCEVLIAAENDLNALDAKSGDG
DTGSTLAGAARALISAVDRLPLADHTQLYRAIGLELSQTMGGSCGVLLAIFFAAAGDAASSGSPMREALQAGLRRMQEIG
GARPGDRTMVDALAPALDVLEESLSEAAKAARAGADRTAHMSKANAGRASYVNARHLVGHADPGAEAVARLFEHLA

Specific function: Catalyzes the phosphorylation of dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaL domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=566, Percent_Identity=39.9293286219081, Blast_Score=321, Evalue=1e-87,
Organism=Escherichia coli, GI87081857, Length=312, Percent_Identity=38.1410256410256, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1787449, Length=200, Percent_Identity=30, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17565018, Length=568, Percent_Identity=36.7957746478873, Blast_Score=292, Evalue=4e-79,
Organism=Saccharomyces cerevisiae, GI6321055, Length=586, Percent_Identity=34.8122866894198, Blast_Score=242, Evalue=1e-64,
Organism=Saccharomyces cerevisiae, GI6323570, Length=557, Percent_Identity=33.7522441651706, Blast_Score=242, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR004007
- InterPro:   IPR012734 [H]

Pfam domain/function: PF02733 Dak1; PF02734 Dak2 [H]

EC number: =2.7.1.29 [H]

Molecular weight: Translated: 57676; Mature: 57676

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRAQLFDQQKFSQIGENMAQFINTKENIVTEAVDALVAASGGKLARLDGYPHIRVVVRN
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEEC
DWDKSKVALISGGGSGHEPAHAGFVGKGMLTAAVCGDIFASPTVDAVLAGILAVTGSSGC
CCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCE
LLIVKNYTGDRLNFGLAAERARPFGLNVEIVIVGDDVALPGLPQARGVAGTLFVHKIAGA
EEEEECCCCCCEECCCHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
LAENGADLAHVAAAARKVVSKTKSIGISLNTCTIPGLPKEDRIPPGMAELGLGIHGEAGV
HHHCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCC
EQVEFKDATGAVAAMVERLSAAMEEKPHVVMVNNLGGTSVIEMSIILNEIRRSAIGEQIT
CCEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
HVIGPAAMMTSLDMHGFSISAYPADDAEIALLKQHTPLAAWPGVSRLGQVAIQALPDGLT
HHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCC
PVVPMPSMHRPTREFLIRCCEVLIAAENDLNALDAKSGDGDTGSTLAGAARALISAVDRL
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
PLADHTQLYRAIGLELSQTMGGSCGVLLAIFFAAAGDAASSGSPMREALQAGLRRMQEIG
CCCHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHC
GARPGDRTMVDALAPALDVLEESLSEAAKAARAGADRTAHMSKANAGRASYVNARHLVGH
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHCCHHHHCCC
ADPGAEAVARLFEHLA
CCCCHHHHHHHHHHCC
>Mature Secondary Structure
MLRAQLFDQQKFSQIGENMAQFINTKENIVTEAVDALVAASGGKLARLDGYPHIRVVVRN
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEEC
DWDKSKVALISGGGSGHEPAHAGFVGKGMLTAAVCGDIFASPTVDAVLAGILAVTGSSGC
CCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCE
LLIVKNYTGDRLNFGLAAERARPFGLNVEIVIVGDDVALPGLPQARGVAGTLFVHKIAGA
EEEEECCCCCCEECCCHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
LAENGADLAHVAAAARKVVSKTKSIGISLNTCTIPGLPKEDRIPPGMAELGLGIHGEAGV
HHHCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCC
EQVEFKDATGAVAAMVERLSAAMEEKPHVVMVNNLGGTSVIEMSIILNEIRRSAIGEQIT
CCEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
HVIGPAAMMTSLDMHGFSISAYPADDAEIALLKQHTPLAAWPGVSRLGQVAIQALPDGLT
HHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCC
PVVPMPSMHRPTREFLIRCCEVLIAAENDLNALDAKSGDGDTGSTLAGAARALISAVDRL
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
PLADHTQLYRAIGLELSQTMGGSCGVLLAIFFAAAGDAASSGSPMREALQAGLRRMQEIG
CCCHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHC
GARPGDRTMVDALAPALDVLEESLSEAAKAARAGADRTAHMSKANAGRASYVNARHLVGH
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHCCHHHHCCC
ADPGAEAVARLFEHLA
CCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA