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The map label for this gene is yegE [C]

Identifier: 82703838

GI number: 82703838

Start: 3125852

End: 3127291

Strand: Direct

Name: yegE [C]

Synonym: Nmul_A2725

Alternate gene names: 82703838

Gene position: 3125852-3127291 (Clockwise)

Preceding gene: 82703820

Following gene: 82703839

Centisome position: 98.17

GC content: 50.35

Gene sequence:

>1440_bases
GTGAACAAAGAGAAAGCTACGGCACCAGGACGAGTAAATAAAAAACTGTTGTCAGCTATCGAGAAACAGAGGGTAACAGC
GCTCGGACTTTCACATGCGAAGCTTCGCCCAGAGAGGATTCTGGACGGTATTACTGATGCGTTTTATACCTTGGATCGCG
AATGGCGCTTCACGTGCCTAAATAAGGAAGCAGAAAATCTGCTGCGACGCTCTCGCAGTGATCTTCTGGGCAAGGTGATC
TGGGAAGAATTCAAGGAGGCAGTAGGAACAATCTTCGATCATGAATGCCGCCGGGCGCTCGTGGAAAATACCACAGTGAA
ATTTGAAAACTTCTACGCTCCTCTAGACGGCTGGTTCGAGGTACACGTTTATCCTTTGGAAGATGGTCTGGCTGTTTATT
TTAATGACATTACGAAGCGTAAACAATCTGAGCAGGCGCGCCAGGAGGCCGAGGCCCGCATTCGCCAGCAGGCTTCCCTG
CTTGATAAGGCAACCGACGCGATCATTGTTCACGGAATCGATCATCGCATTCAGTTTTGGAATCAGGGCGCGCAGCGGTT
ATACGGATGGACCCCTGAAGAGGTCCTCGGTAAATCCATAGAGATGCTGTATGACAATCCCTTAGCCTTCCATGAAGCGA
GCAAATTGCTATTGAATAAAGGCGAATGGAGGGGGGAGATCGCACAGCGGCGCAAAGATGGGAGTATATTGCTTGCTGAA
GCACACTGGACTTTGGTTAAAAATGACGAGGGGCAAGCGCAATCTGTTTTCGCAATCAACACCGATATTACCCAGCGCAA
GATGGCGGAAAACAAAATCGAACACCTCGCCTTCTATGATTCCTTGACCGGATTGCCCAATAGGCAACTCCTGCTGGACC
GGCTGAGTCAGGCACTCTCGGCGAGAGCCCGGAAACATCGCATGGGCGCGTTACTGTTTATCGACCTCGATAACTTTAAA
TTACTCAATGATACGTTCGGCCACGATTTGGGGGACCTGTTGCTGCAGCAGCTGGCTCCTCGCCTGATCTCCTGCATACG
GGAAAGCGACACGGTCGCTCGCCTGGGCGGCGACGAGTTTGTAGTAATACTGATAACGGACTTTAGCGAAAATTATGAAG
AATCCCTTGCTCAGATAAAGGCCATTTGCGAGAGGATTCACAGCGCATTCAATCAGCCTTTTAATCTCCGTGCATATAAA
CATCACAGCACGGCGAGCATCGGCGTCGTACTATTTAACGATCAATCGCACACGACAGACGAGTTGCTCAAGCAGGCGGA
TCTCGCGATGTATCAGGCAAAAGCATCAGGCCGCAACGCAATGTGCTTTTTCGATCCGGACGCAAGCGGCAATGAATGCC
TGCACCCTTCTGGAGGCGGATTTGCACAAAAGCTGGAAGAGAAACGAATTTGTTCTCCATTATCAGCCCCGGATGGATAG

Upstream 100 bases:

>100_bases
CCGGGGCCAGTAGTCAAAAATATGCCCTTTCATATCGAAGGATCGTTAAAATCGTAGGTGAACTTAGGTAGAGTTTTGAA
TCTATCAGGAGATCATCTCA

Downstream 100 bases:

>100_bases
CAGCGACTTATGGGGGCCGAAGCGCTCATTCGGTGGCAGCGGCTTGTTTTCTCCAGAGTGATTTCTGGGGAGAAACTGCA
CGCCCGGGATGGGGGTATGC

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MNKEKATAPGRVNKKLLSAIEKQRVTALGLSHAKLRPERILDGITDAFYTLDREWRFTCLNKEAENLLRRSRSDLLGKVI
WEEFKEAVGTIFDHECRRALVENTTVKFENFYAPLDGWFEVHVYPLEDGLAVYFNDITKRKQSEQARQEAEARIRQQASL
LDKATDAIIVHGIDHRIQFWNQGAQRLYGWTPEEVLGKSIEMLYDNPLAFHEASKLLLNKGEWRGEIAQRRKDGSILLAE
AHWTLVKNDEGQAQSVFAINTDITQRKMAENKIEHLAFYDSLTGLPNRQLLLDRLSQALSARARKHRMGALLFIDLDNFK
LLNDTFGHDLGDLLLQQLAPRLISCIRESDTVARLGGDEFVVILITDFSENYEESLAQIKAICERIHSAFNQPFNLRAYK
HHSTASIGVVLFNDQSHTTDELLKQADLAMYQAKASGRNAMCFFDPDASGNECLHPSGGGFAQKLEEKRICSPLSAPDG

Sequences:

>Translated_479_residues
MNKEKATAPGRVNKKLLSAIEKQRVTALGLSHAKLRPERILDGITDAFYTLDREWRFTCLNKEAENLLRRSRSDLLGKVI
WEEFKEAVGTIFDHECRRALVENTTVKFENFYAPLDGWFEVHVYPLEDGLAVYFNDITKRKQSEQARQEAEARIRQQASL
LDKATDAIIVHGIDHRIQFWNQGAQRLYGWTPEEVLGKSIEMLYDNPLAFHEASKLLLNKGEWRGEIAQRRKDGSILLAE
AHWTLVKNDEGQAQSVFAINTDITQRKMAENKIEHLAFYDSLTGLPNRQLLLDRLSQALSARARKHRMGALLFIDLDNFK
LLNDTFGHDLGDLLLQQLAPRLISCIRESDTVARLGGDEFVVILITDFSENYEESLAQIKAICERIHSAFNQPFNLRAYK
HHSTASIGVVLFNDQSHTTDELLKQADLAMYQAKASGRNAMCFFDPDASGNECLHPSGGGFAQKLEEKRICSPLSAPDG
>Mature_479_residues
MNKEKATAPGRVNKKLLSAIEKQRVTALGLSHAKLRPERILDGITDAFYTLDREWRFTCLNKEAENLLRRSRSDLLGKVI
WEEFKEAVGTIFDHECRRALVENTTVKFENFYAPLDGWFEVHVYPLEDGLAVYFNDITKRKQSEQARQEAEARIRQQASL
LDKATDAIIVHGIDHRIQFWNQGAQRLYGWTPEEVLGKSIEMLYDNPLAFHEASKLLLNKGEWRGEIAQRRKDGSILLAE
AHWTLVKNDEGQAQSVFAINTDITQRKMAENKIEHLAFYDSLTGLPNRQLLLDRLSQALSARARKHRMGALLFIDLDNFK
LLNDTFGHDLGDLLLQQLAPRLISCIRESDTVARLGGDEFVVILITDFSENYEESLAQIKAICERIHSAFNQPFNLRAYK
HHSTASIGVVLFNDQSHTTDELLKQADLAMYQAKASGRNAMCFFDPDASGNECLHPSGGGFAQKLEEKRICSPLSAPDG

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=320, Percent_Identity=33.125, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1787541, Length=187, Percent_Identity=34.7593582887701, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI87081977, Length=160, Percent_Identity=40, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786584, Length=178, Percent_Identity=36.5168539325843, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87081881, Length=184, Percent_Identity=34.2391304347826, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788956, Length=160, Percent_Identity=37.5, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1787816, Length=213, Percent_Identity=31.4553990610329, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI145693134, Length=177, Percent_Identity=36.1581920903955, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787262, Length=168, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87082007, Length=189, Percent_Identity=30.1587301587302, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87081974, Length=108, Percent_Identity=40.7407407407407, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1787802, Length=190, Percent_Identity=28.9473684210526, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 54370; Mature: 54370

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKEKATAPGRVNKKLLSAIEKQRVTALGLSHAKLRPERILDGITDAFYTLDREWRFTCL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHCCCCCEEEEE
NKEAENLLRRSRSDLLGKVIWEEFKEAVGTIFDHECRRALVENTTVKFENFYAPLDGWFE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCEEE
VHVYPLEDGLAVYFNDITKRKQSEQARQEAEARIRQQASLLDKATDAIIVHGIDHRIQFW
EEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHH
NQGAQRLYGWTPEEVLGKSIEMLYDNPLAFHEASKLLLNKGEWRGEIAQRRKDGSILLAE
HHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCEEEEE
AHWTLVKNDEGQAQSVFAINTDITQRKMAENKIEHLAFYDSLTGLPNRQLLLDRLSQALS
EEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ARARKHRMGALLFIDLDNFKLLNDTFGHDLGDLLLQQLAPRLISCIRESDTVARLGGDEF
HHHHHHHCCEEEEEECCCCEEHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCE
VVILITDFSENYEESLAQIKAICERIHSAFNQPFNLRAYKHHSTASIGVVLFNDQSHTTD
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCCCCHH
ELLKQADLAMYQAKASGRNAMCFFDPDASGNECLHPSGGGFAQKLEEKRICSPLSAPDG
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNKEKATAPGRVNKKLLSAIEKQRVTALGLSHAKLRPERILDGITDAFYTLDREWRFTCL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHCCCCCEEEEE
NKEAENLLRRSRSDLLGKVIWEEFKEAVGTIFDHECRRALVENTTVKFENFYAPLDGWFE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCEEE
VHVYPLEDGLAVYFNDITKRKQSEQARQEAEARIRQQASLLDKATDAIIVHGIDHRIQFW
EEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHH
NQGAQRLYGWTPEEVLGKSIEMLYDNPLAFHEASKLLLNKGEWRGEIAQRRKDGSILLAE
HHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCEEEEE
AHWTLVKNDEGQAQSVFAINTDITQRKMAENKIEHLAFYDSLTGLPNRQLLLDRLSQALS
EEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ARARKHRMGALLFIDLDNFKLLNDTFGHDLGDLLLQQLAPRLISCIRESDTVARLGGDEF
HHHHHHHCCEEEEEECCCCEEHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCE
VVILITDFSENYEESLAQIKAICERIHSAFNQPFNLRAYKHHSTASIGVVLFNDQSHTTD
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCCCCHH
ELLKQADLAMYQAKASGRNAMCFFDPDASGNECLHPSGGGFAQKLEEKRICSPLSAPDG
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]