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The map label for this gene is groES

Identifier: 82703462

GI number: 82703462

Start: 2672987

End: 2673277

Strand: Reverse

Name: groES

Synonym: Nmul_A2345

Alternate gene names: 82703462

Gene position: 2673277-2672987 (Counterclockwise)

Preceding gene: 82703464

Following gene: 82703461

Centisome position: 83.95

GC content: 53.61

Gene sequence:

>291_bases
ATGCAGATTCGTCCCTTACACGACCGCGTCATCGTCAAGCGGCTGGAAGAAGAGCGCAAGACCGCATCCGGTATTGTCAT
ACCTGACAGCGCTGCGGAGAAGCCGGATCAGGGCGAAATTATCGCGGTAGGTAAAGGCAAGGTCGGCGACGACGGCAATG
TCCGTCCGCTGGAAGTGAAAGTCGGCGATAAGGTATTGTTCGGCAAATATTCCGGACAGACCGTGAAGATATCGGGAGAA
GAACTTCTGGTGATGCGCGAAGAAGACATCATGGGCGTTGTTGAAGGTTAA

Upstream 100 bases:

>100_bases
GTGCTAATAATTTCGGTAAATGGCTCGGGAAACCCCATGCCAGCGGCAATCCCGAAGGATTTCATTCGTTTTAATTTTTT
AAAACACAGGAGAAGAAAAC

Downstream 100 bases:

>100_bases
TTTTCGCAAGACGTCTTGCACAATATTTTCTGGAAATTAGGAGAAACGGATTATGGCAGCGAAAGAGGTTAAATTCAGCG
ATTCAGCTCGCCACAAGATG

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 96; Mature: 96

Protein sequence:

>96_residues
MQIRPLHDRVIVKRLEEERKTASGIVIPDSAAEKPDQGEIIAVGKGKVGDDGNVRPLEVKVGDKVLFGKYSGQTVKISGE
ELLVMREEDIMGVVEG

Sequences:

>Translated_96_residues
MQIRPLHDRVIVKRLEEERKTASGIVIPDSAAEKPDQGEIIAVGKGKVGDDGNVRPLEVKVGDKVLFGKYSGQTVKISGE
ELLVMREEDIMGVVEG
>Mature_96_residues
MQIRPLHDRVIVKRLEEERKTASGIVIPDSAAEKPDQGEIIAVGKGKVGDDGNVRPLEVKVGDKVLFGKYSGQTVKISGE
ELLVMREEDIMGVVEG

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Escherichia coli, GI1790585, Length=97, Percent_Identity=54.639175257732, Blast_Score=102, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17555568, Length=93, Percent_Identity=35.4838709677419, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324594, Length=91, Percent_Identity=40.6593406593407, Blast_Score=75, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356029, Length=97, Percent_Identity=39.1752577319588, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_NITMU (Q2Y6I5)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_413028.1
- ProteinModelPortal:   Q2Y6I5
- SMR:   Q2Y6I5
- STRING:   Q2Y6I5
- GeneID:   3784749
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A2345
- eggNOG:   COG0234
- HOGENOM:   HBG703377
- OMA:   QDRIIVK
- PhylomeDB:   Q2Y6I5
- ProtClustDB:   PRK00364
- BioCyc:   NMUL323848:NMUL_A2345-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10455; Mature: 10455

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIRPLHDRVIVKRLEEERKTASGIVIPDSAAEKPDQGEIIAVGKGKVGDDGNVRPLEVK
CCCCCCHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEE
VGDKVLFGKYSGQTVKISGEELLVMREEDIMGVVEG
ECCEEEEEECCCCEEEECCCEEEEEECCCEEEEECC
>Mature Secondary Structure
MQIRPLHDRVIVKRLEEERKTASGIVIPDSAAEKPDQGEIIAVGKGKVGDDGNVRPLEVK
CCCCCCHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEE
VGDKVLFGKYSGQTVKISGEELLVMREEDIMGVVEG
ECCEEEEEECCCCEEEECCCEEEEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA