Click here to switch to the map view.

The map label for this gene is ycgR

Identifier: 82702733

GI number: 82702733

Start: 1843655

End: 1844431

Strand: Direct

Name: ycgR

Synonym: Nmul_A1606

Alternate gene names: 82702733

Gene position: 1843655-1844431 (Clockwise)

Preceding gene: 82702727

Following gene: 82702734

Centisome position: 57.9

GC content: 50.32

Gene sequence:

>777_bases
ATGAGCAGGACCTGGATAGATATCATGGCAGACAGCAAACCCGACCTTCCTGATAACAACAAGAAATATCGCATTTCGTC
GAAAAGCGGCATTCTCTCCGTGCTGCGAGTGATGATAAGGAATAATTCGCAAGCCACCTGTTATTTTGGTGATGCCGGCA
GCTTTTTCCCGACCGCTCTTTTGAATCTCGACAGCCAGCGGGGGGAAATGGTGCTCGATTATGGTCCGAATGAGGAAATC
AACCAGCAGGCATTGCAAGTTGAAAAATGGAATGTTGTTGCATTTCCCAACCAGGTGAAGGTTCAATTTTCCTGCCAGCA
AATCGGGAAAACAGAGTTCGAGGGGCGCAATGCCTTCCTTGCACAGATCCCCACAAGTCTGTTGCGTATGCAAAAGCGGG
AGTACTATCGCGTTGCCACACCTACGACTGCTCCCGTAAAATGTGTGATTCCCCTACTTCTGGGAAAATCGCCTTCCACC
GTGGAAGTACTCCTGCAGGACCTCAGCTGCGGTGGGATGGCTGTTATCGACTCGAACGGTAGAAGCAATTTCGAGGAAGG
AAGCGTTTACGAAAATTGCTGCATTGTATTACCCGATATCGGTACGGTTAATGTATCCATGCGGATAATCCGCGTGGAAC
CGGCCGATACCGGATTCGTACATGATCTCCAATCCCAGCGCGTCAGTTGCGAGTTTGCCGATGCAGGCGAAAATGCGCTG
TCTCTGATCCAGCGTTACATAACCAGACTGGAGCTGGAGCAGAAGCGGGCATCATAG

Upstream 100 bases:

>100_bases
GATGCGAAAGCGATGTTGCAGTGACAGGACTTAAGGTGAAGAGTGATATTTCCGCTTGCACCAGTTGTGATTGGAGCAGC
ACGGCGAAATCCGAATAGGA

Downstream 100 bases:

>100_bases
GGCATTCCATCGTCCGCATCCCCGGACTCCCCGGGGATTCGTGAAAACCTACTTTAAGCAGTTCGGCAACCGACGTTCTG
AGTATAGACATTTGCAATCG

Product: YcgR

Products: NA

Alternate protein names: Cyclic di-GMP binding protein YcgR

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MSRTWIDIMADSKPDLPDNNKKYRISSKSGILSVLRVMIRNNSQATCYFGDAGSFFPTALLNLDSQRGEMVLDYGPNEEI
NQQALQVEKWNVVAFPNQVKVQFSCQQIGKTEFEGRNAFLAQIPTSLLRMQKREYYRVATPTTAPVKCVIPLLLGKSPST
VEVLLQDLSCGGMAVIDSNGRSNFEEGSVYENCCIVLPDIGTVNVSMRIIRVEPADTGFVHDLQSQRVSCEFADAGENAL
SLIQRYITRLELEQKRAS

Sequences:

>Translated_258_residues
MSRTWIDIMADSKPDLPDNNKKYRISSKSGILSVLRVMIRNNSQATCYFGDAGSFFPTALLNLDSQRGEMVLDYGPNEEI
NQQALQVEKWNVVAFPNQVKVQFSCQQIGKTEFEGRNAFLAQIPTSLLRMQKREYYRVATPTTAPVKCVIPLLLGKSPST
VEVLLQDLSCGGMAVIDSNGRSNFEEGSVYENCCIVLPDIGTVNVSMRIIRVEPADTGFVHDLQSQRVSCEFADAGENAL
SLIQRYITRLELEQKRAS
>Mature_257_residues
SRTWIDIMADSKPDLPDNNKKYRISSKSGILSVLRVMIRNNSQATCYFGDAGSFFPTALLNLDSQRGEMVLDYGPNEEIN
QQALQVEKWNVVAFPNQVKVQFSCQQIGKTEFEGRNAFLAQIPTSLLRMQKREYYRVATPTTAPVKCVIPLLLGKSPSTV
EVLLQDLSCGGMAVIDSNGRSNFEEGSVYENCCIVLPDIGTVNVSMRIIRVEPADTGFVHDLQSQRVSCEFADAGENALS
LIQRYITRLELEQKRAS

Specific function: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility

COG id: COG5581

COG function: function code M; Predicted glycosyltransferase

Gene ontology:

Cell location: Bacterial flagellum basal body

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PilZ domain

Homologues:

Organism=Escherichia coli, GI1787443, Length=190, Percent_Identity=25.7894736842105, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YCGR_NITMU (Q2Y8L4)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_412299.1
- ProteinModelPortal:   Q2Y8L4
- STRING:   Q2Y8L4
- GeneID:   3784838
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A1606
- eggNOG:   COG5581
- OMA:   QLGFRFL
- PhylomeDB:   Q2Y8L4
- BioCyc:   NMUL323848:NMUL_A1606-MONOMER
- HAMAP:   MF_01457
- InterPro:   IPR009875
- InterPro:   IPR012349
- InterPro:   IPR009926
- Gene3D:   G3DSA:2.30.110.10

Pfam domain/function: PF07238 PilZ; PF07317 YcgR

EC number: NA

Molecular weight: Translated: 28797; Mature: 28666

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRTWIDIMADSKPDLPDNNKKYRISSKSGILSVLRVMIRNNSQATCYFGDAGSFFPTAL
CCCEEEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHH
LNLDSQRGEMVLDYGPNEEINQQALQVEKWNVVAFPNQVKVQFSCQQIGKTEFEGRNAFL
HCCCCCCCCEEEECCCCCHHHHHHHEEECCEEEECCCEEEEEEEHHHCCCCCCCCCCEEH
AQIPTSLLRMQKREYYRVATPTTAPVKCVIPLLLGKSPSTVEVLLQDLSCGGMAVIDSNG
HHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEECCC
RSNFEEGSVYENCCIVLPDIGTVNVSMRIIRVEPADTGFVHDLQSQRVSCEFADAGENAL
CCCCCCCCCCCCEEEEECCCCEEEEEEEEEEECCCCCCHHHHHHCCCEEEEECCCCHHHH
SLIQRYITRLELEQKRAS
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRTWIDIMADSKPDLPDNNKKYRISSKSGILSVLRVMIRNNSQATCYFGDAGSFFPTAL
CCEEEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHH
LNLDSQRGEMVLDYGPNEEINQQALQVEKWNVVAFPNQVKVQFSCQQIGKTEFEGRNAFL
HCCCCCCCCEEEECCCCCHHHHHHHEEECCEEEECCCEEEEEEEHHHCCCCCCCCCCEEH
AQIPTSLLRMQKREYYRVATPTTAPVKCVIPLLLGKSPSTVEVLLQDLSCGGMAVIDSNG
HHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEECCC
RSNFEEGSVYENCCIVLPDIGTVNVSMRIIRVEPADTGFVHDLQSQRVSCEFADAGENAL
CCCCCCCCCCCCEEEEECCCCEEEEEEEEEEECCCCCCHHHHHHCCCEEEEECCCCHHHH
SLIQRYITRLELEQKRAS
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA