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The map label for this gene is cotA [H]

Identifier: 82702734

GI number: 82702734

Start: 1844740

End: 1846803

Strand: Direct

Name: cotA [H]

Synonym: Nmul_A1607

Alternate gene names: 82702734

Gene position: 1844740-1846803 (Clockwise)

Preceding gene: 82702733

Following gene: 82702735

Centisome position: 57.93

GC content: 56.88

Gene sequence:

>2064_bases
ATGGTTTCGCGGCGCGGATTCCTTAAATATACTGCCGGGGGCTTGCTAACCCTTTTTGGATCTGATCGGCTTAACGGCCT
CTCCAGAGCGATTGCCGCGATTCCCGGCGGGTCACTCAACCCGGAACTTGTCGATAAATTCCGGACACCACTATTCATTC
CACCGGCGATGCCTGCCGCTGGAAAGAAAGTCATTGGGGATGGACGCCGTGTGGATTACTACGAAATTTCGGTAAAACAG
TTTTCACAGCAGATATTGCCTCGCGGGTTTCCTCCGACAACCGTATGGGGATACGGCCCCGCCTTTCCTGAAAAGCGGCG
ATCTTTTGCTCATCGCGCCCCAGGTTTTACCATTGAGGCAAAATGGCAGGAACCAGTGATTGTAAAATGGATCAACGGCC
TCAAGGATGCCACTACCGCAGGCTTCCTCCCGCCCTTGCTGCCGGTCGATCCCACCCTGCATTGGGCAAACCCGCCAGGC
GGCATAGCTCATCGCGACATGAGTCCCTCTTTCAGGGCGACCCCCGCCGCCTATCGCGGCCCTGTCCCGATTGTCACCCA
TCTGCATGGCGCGATCGGGGTTGCCGGTCATAGCGACGGCCACCCTGAAGCGTGGTACCTGCCGGCGGCGGCAGGCATTC
CTTCGGAATATGCCGCGTTTGGAACCTGGTATCAATTCTTCAATCGCGAGGCGAGCCTCGACGTGGGAGCGTGGGAGCCG
GGCAGCGCTACGTTCACTTATCCCAACATGCAGACTTCGATGCTCTGGTACCACGATCATGCGTTGGGGATGACGCGTAC
GAACGTCTATGCCGGCCTGGCGGGCATTTATATGATCCGCGGGGGCCCTGAAGGAGACGGTGCGATAAGGGATGCCCGAA
GCGGCATGCGAGGCGTCCTGCCTCGCTCCACTTCCACGCATGGCCCGATGCATCTTCCGCAGCACAGGAATATCCGTGAA
ATTCCCCTCATGATACAGGACCGGTCATTCAATATCGACGGCTCTCTCTTCTATCCTCATTCGAGGGCCTTTTTTGACGG
GATCCCGGGGCCATTCATTCCTGACACCGATATTCCGCCCATCTGGAACCCGGAGTTTTTCGCCAATATGATGGTGGTAA
ACGGAAATACATGGCCCTTCCAGACAGTTGAGCAGGCCCGTTACCGGTATCGGCTGTTGAACGCCTGCAACTCGCGTTTT
CTCATTCTCGACTTTAACAGCATTCCCGGTATCGAGGTCTGGATGATAGGTGGCGACAGCGGTTTTCTTCCGGCGCCGGC
AAACATGACAGCAGTGAATGCAAACCGCATTCTCCTGGGGCCTTCCGAGCGGGCGGATGTGATCGTCGATTTCACTCGGG
TGCCCATCGGACGACATGTACTGAAAAATATCGGTCCGGATGAACCCTTTGGGGGAGGAGTGCCGGGCACCGATTTTCAA
ATGGCGGACCCTCGCTCTAGCGGGCTGATCATGCAGTTTCACGTGACTCTCGCTCAAGAGGAGGACCGTTCGACGCCGCC
GCAATACCTGCTGCTTCCGAATACTCCTCCCCTCCCGCGAGAGACATTTATCCGTCGCCTGGCGCTGCTGGAAAAGGAAT
CCTCAAGCTTCGACGAATCCCCCGCCGCCGCCTTTTTAGGTATCGTTCTGGGCGACCCGGGAGCGGGTCCGGCGGCCTGC
ATCGCCCGTGGATGGAAGGATCCCGTTACTCAGAACCCGGCAGTGGGGACAACGGAAATCTGGGAGTTCTACAATATGAC
GGAAGATGCGCATCCCATGCATGTCCACGCCGTATCCTTCGAATTGGTCAACAGACAGGCCATACTTGTAAATGAAGAAA
GCGGGACAGTCCAGCTGGAAGCGGGATCGTCTCCTGTATCCCCCGAACCTTGGGAGTTGGGGCGCAAGGATACGGTTATT
GCCTACCCCAGCCAAGTTACGCGCGTGCGCATGACCTTCATCAGAGAAGGACAATACGTCTGGCATTGCCACATCCTCGA
ACACGAAGACAATCAAATGATGCTACCGTATCGCATCGGTCAGGCGAAACAACGAATACCGTAG

Upstream 100 bases:

>100_bases
CAACAATAAATACTGCATAACTCCCGATATCTCCGAAGCTGGCACGTGCAAATCGAGAAGAATAGGAGCTTTGCTGGATG
TGGATCAGAAGGAGCTCCTA

Downstream 100 bases:

>100_bases
CAACTCCCAGCCGGCGGACAACCGCTGGCGTGCGGCAGCCAGGTGTGCGGGATTCCGCGGATAAGAAGAATCCGGCTTCA
GGAAAAAGACGTTTGCCTGG

Product: multicopper oxidase, type 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 687; Mature: 687

Protein sequence:

>687_residues
MVSRRGFLKYTAGGLLTLFGSDRLNGLSRAIAAIPGGSLNPELVDKFRTPLFIPPAMPAAGKKVIGDGRRVDYYEISVKQ
FSQQILPRGFPPTTVWGYGPAFPEKRRSFAHRAPGFTIEAKWQEPVIVKWINGLKDATTAGFLPPLLPVDPTLHWANPPG
GIAHRDMSPSFRATPAAYRGPVPIVTHLHGAIGVAGHSDGHPEAWYLPAAAGIPSEYAAFGTWYQFFNREASLDVGAWEP
GSATFTYPNMQTSMLWYHDHALGMTRTNVYAGLAGIYMIRGGPEGDGAIRDARSGMRGVLPRSTSTHGPMHLPQHRNIRE
IPLMIQDRSFNIDGSLFYPHSRAFFDGIPGPFIPDTDIPPIWNPEFFANMMVVNGNTWPFQTVEQARYRYRLLNACNSRF
LILDFNSIPGIEVWMIGGDSGFLPAPANMTAVNANRILLGPSERADVIVDFTRVPIGRHVLKNIGPDEPFGGGVPGTDFQ
MADPRSSGLIMQFHVTLAQEEDRSTPPQYLLLPNTPPLPRETFIRRLALLEKESSSFDESPAAAFLGIVLGDPGAGPAAC
IARGWKDPVTQNPAVGTTEIWEFYNMTEDAHPMHVHAVSFELVNRQAILVNEESGTVQLEAGSSPVSPEPWELGRKDTVI
AYPSQVTRVRMTFIREGQYVWHCHILEHEDNQMMLPYRIGQAKQRIP

Sequences:

>Translated_687_residues
MVSRRGFLKYTAGGLLTLFGSDRLNGLSRAIAAIPGGSLNPELVDKFRTPLFIPPAMPAAGKKVIGDGRRVDYYEISVKQ
FSQQILPRGFPPTTVWGYGPAFPEKRRSFAHRAPGFTIEAKWQEPVIVKWINGLKDATTAGFLPPLLPVDPTLHWANPPG
GIAHRDMSPSFRATPAAYRGPVPIVTHLHGAIGVAGHSDGHPEAWYLPAAAGIPSEYAAFGTWYQFFNREASLDVGAWEP
GSATFTYPNMQTSMLWYHDHALGMTRTNVYAGLAGIYMIRGGPEGDGAIRDARSGMRGVLPRSTSTHGPMHLPQHRNIRE
IPLMIQDRSFNIDGSLFYPHSRAFFDGIPGPFIPDTDIPPIWNPEFFANMMVVNGNTWPFQTVEQARYRYRLLNACNSRF
LILDFNSIPGIEVWMIGGDSGFLPAPANMTAVNANRILLGPSERADVIVDFTRVPIGRHVLKNIGPDEPFGGGVPGTDFQ
MADPRSSGLIMQFHVTLAQEEDRSTPPQYLLLPNTPPLPRETFIRRLALLEKESSSFDESPAAAFLGIVLGDPGAGPAAC
IARGWKDPVTQNPAVGTTEIWEFYNMTEDAHPMHVHAVSFELVNRQAILVNEESGTVQLEAGSSPVSPEPWELGRKDTVI
AYPSQVTRVRMTFIREGQYVWHCHILEHEDNQMMLPYRIGQAKQRIP
>Mature_687_residues
MVSRRGFLKYTAGGLLTLFGSDRLNGLSRAIAAIPGGSLNPELVDKFRTPLFIPPAMPAAGKKVIGDGRRVDYYEISVKQ
FSQQILPRGFPPTTVWGYGPAFPEKRRSFAHRAPGFTIEAKWQEPVIVKWINGLKDATTAGFLPPLLPVDPTLHWANPPG
GIAHRDMSPSFRATPAAYRGPVPIVTHLHGAIGVAGHSDGHPEAWYLPAAAGIPSEYAAFGTWYQFFNREASLDVGAWEP
GSATFTYPNMQTSMLWYHDHALGMTRTNVYAGLAGIYMIRGGPEGDGAIRDARSGMRGVLPRSTSTHGPMHLPQHRNIRE
IPLMIQDRSFNIDGSLFYPHSRAFFDGIPGPFIPDTDIPPIWNPEFFANMMVVNGNTWPFQTVEQARYRYRLLNACNSRF
LILDFNSIPGIEVWMIGGDSGFLPAPANMTAVNANRILLGPSERADVIVDFTRVPIGRHVLKNIGPDEPFGGGVPGTDFQ
MADPRSSGLIMQFHVTLAQEEDRSTPPQYLLLPNTPPLPRETFIRRLALLEKESSSFDESPAAAFLGIVLGDPGAGPAAC
IARGWKDPVTQNPAVGTTEIWEFYNMTEDAHPMHVHAVSFELVNRQAILVNEESGTVQLEAGSSPVSPEPWELGRKDTVI
AYPSQVTRVRMTFIREGQYVWHCHILEHEDNQMMLPYRIGQAKQRIP

Specific function: Involved in brown pigmentation during sporogenesis [H]

COG id: COG2132

COG function: function code Q; Putative multicopper oxidases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To S.antibioticus phenoxazinone synthase (phsA) [H]

Homologues:

Organism=Escherichia coli, GI1789394, Length=200, Percent_Identity=28, Blast_Score=73, Evalue=7e-14,

Paralogues:

None

Copy number: 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001117
- InterPro:   IPR011706
- InterPro:   IPR011707
- InterPro:   IPR008972 [H]

Pfam domain/function: PF00394 Cu-oxidase; PF07731 Cu-oxidase_2; PF07732 Cu-oxidase_3 [H]

EC number: NA

Molecular weight: Translated: 75913; Mature: 75913

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSRRGFLKYTAGGLLTLFGSDRLNGLSRAIAAIPGGSLNPELVDKFRTPLFIPPAMPAA
CCCCCCCEEEECCCEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEECCCCCCC
GKKVIGDGRRVDYYEISVKQFSQQILPRGFPPTTVWGYGPAFPEKRRSFAHRAPGFTIEA
CCCEECCCCEEEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEE
KWQEPVIVKWINGLKDATTAGFLPPLLPVDPTLHWANPPGGIAHRDMSPSFRATPAAYRG
CCCCCCHHHHHHCCHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCC
PVPIVTHLHGAIGVAGHSDGHPEAWYLPAAAGIPSEYAAFGTWYQFFNREASLDVGAWEP
CCCHHHHCCCCEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
GSATFTYPNMQTSMLWYHDHALGMTRTNVYAGLAGIYMIRGGPEGDGAIRDARSGMRGVL
CCEEEECCCCCEEEEEEECCCCCCCHHHHHHCEEEEEEEECCCCCCCHHHHHHCCCCCCC
PRSTSTHGPMHLPQHRNIREIPLMIQDRSFNIDGSLFYPHSRAFFDGIPGPFIPDTDIPP
CCCCCCCCCCCCCCCCCCEECCEEEECCCCCCCCEEECCCCHHHHCCCCCCCCCCCCCCC
IWNPEFFANMMVVNGNTWPFQTVEQARYRYRLLNACNSRFLILDFNSIPGIEVWMIGGDS
CCCHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECCC
GFLPAPANMTAVNANRILLGPSERADVIVDFTRVPIGRHVLKNIGPDEPFGGGVPGTDFQ
CCCCCCCCEEEECCCEEEECCCCCCCEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCE
MADPRSSGLIMQFHVTLAQEEDRSTPPQYLLLPNTPPLPRETFIRRLALLEKESSSFDES
ECCCCCCCEEEEEEEEEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCC
PAAAFLGIVLGDPGAGPAACIARGWKDPVTQNPAVGTTEIWEFYNMTEDAHPMHVHAVSF
CCCEEEEEEECCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEEEEE
ELVNRQAILVNEESGTVQLEAGSSPVSPEPWELGRKDTVIAYPSQVTRVRMTFIREGQYV
EEECCEEEEEECCCCEEEEECCCCCCCCCCHHCCCCCEEEECCCHHHHEEEEEEECCCEE
WHCHILEHEDNQMMLPYRIGQAKQRIP
EEEEEEEECCCCEEEEEECCCHHHCCC
>Mature Secondary Structure
MVSRRGFLKYTAGGLLTLFGSDRLNGLSRAIAAIPGGSLNPELVDKFRTPLFIPPAMPAA
CCCCCCCEEEECCCEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEECCCCCCC
GKKVIGDGRRVDYYEISVKQFSQQILPRGFPPTTVWGYGPAFPEKRRSFAHRAPGFTIEA
CCCEECCCCEEEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEE
KWQEPVIVKWINGLKDATTAGFLPPLLPVDPTLHWANPPGGIAHRDMSPSFRATPAAYRG
CCCCCCHHHHHHCCHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCC
PVPIVTHLHGAIGVAGHSDGHPEAWYLPAAAGIPSEYAAFGTWYQFFNREASLDVGAWEP
CCCHHHHCCCCEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
GSATFTYPNMQTSMLWYHDHALGMTRTNVYAGLAGIYMIRGGPEGDGAIRDARSGMRGVL
CCEEEECCCCCEEEEEEECCCCCCCHHHHHHCEEEEEEEECCCCCCCHHHHHHCCCCCCC
PRSTSTHGPMHLPQHRNIREIPLMIQDRSFNIDGSLFYPHSRAFFDGIPGPFIPDTDIPP
CCCCCCCCCCCCCCCCCCEECCEEEECCCCCCCCEEECCCCHHHHCCCCCCCCCCCCCCC
IWNPEFFANMMVVNGNTWPFQTVEQARYRYRLLNACNSRFLILDFNSIPGIEVWMIGGDS
CCCHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECCC
GFLPAPANMTAVNANRILLGPSERADVIVDFTRVPIGRHVLKNIGPDEPFGGGVPGTDFQ
CCCCCCCCEEEECCCEEEECCCCCCCEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCE
MADPRSSGLIMQFHVTLAQEEDRSTPPQYLLLPNTPPLPRETFIRRLALLEKESSSFDES
ECCCCCCCEEEEEEEEEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCC
PAAAFLGIVLGDPGAGPAACIARGWKDPVTQNPAVGTTEIWEFYNMTEDAHPMHVHAVSF
CCCEEEEEEECCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEEEEE
ELVNRQAILVNEESGTVQLEAGSSPVSPEPWELGRKDTVIAYPSQVTRVRMTFIREGQYV
EEECCEEEEEECCCCEEEEECCCCCCCCCCHHCCCCCEEEECCCHHHHEEEEEEECCCEE
WHCHILEHEDNQMMLPYRIGQAKQRIP
EEEEEEEECCCCEEEEEECCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969499; 9455482; 9384377; 2821284; 3135411 [H]