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The map label for this gene is motA [H]

Identifier: 82702436

GI number: 82702436

Start: 1497351

End: 1498211

Strand: Direct

Name: motA [H]

Synonym: Nmul_A1307

Alternate gene names: 82702436

Gene position: 1497351-1498211 (Clockwise)

Preceding gene: 82702435

Following gene: 82702437

Centisome position: 47.02

GC content: 52.73

Gene sequence:

>861_bases
ATGTTGGTCATTATTGGATCTCTCATTGTGCTGGGATCGGTGTTCGGTGGTTTTGCTTTGACTGGCGGACACCTGGCTGC
GCTGTTTCAACCAGTGGAGCTTCTCATGATCGGGGGTGCGGCAATGGGCGCATTTACCCTGGGCAATACGAAAAAAGCCC
TCAAAGCCACCCTCAAGTCACTTCCCAAGGTTGTGCAGCCTCCCCGGTACACCAAAGCCTTGTATATGGACCTGATGGCG
CTGCTCTATGATCTTCTGGTCAAGGTTCGCAAGGAAGGATTGATGTCGATCGAGCCTGATGTCGACGATCCCAATGAAAG
CGCGATTTTTGCCAATTATCCCGATATTCTTGCCGAGCCAGTTGCGCTCGAGTTCTTGACCGACTACCTTCGTCTCATGG
TGGCAGGCAATCTCAACGCGTTCGAACTGGAAAACCTGATGGATAACGAAATAGAGACTCATCACCAGGAAGGCGAAATC
CCCGTGCATTGCATAAGCCGGTTGGCAGACAGCATGCCGGCATTCGGCATTGTTGCAGCGGTAATGGGAGTGATACATAC
CATGGCATCTGTAGGCCTACCGCCTTCGGAACTGGGTGTGCTTGTCGCTCAAGCGCTCGTGGGAACTTTCCTCGGTATTC
TTCTCGGGTACGGATTCGTCGGGCCCGTTGCCTCGATACTGGAACAGAGGCTCAATGAATCGACGAAGATACTGCAATGC
ATCCGGGTCACCTTGCTGGCAAGCATCAATGGCTATACTCCTGCACTGGCAGTCGAATTTGGACGAAAAGTGCTCTACTC
GACGGAGCGGCCCAGTTTCGCTGAACTGGAAAGCCACGTCAGACGGGCAAAAGACAAATAA

Upstream 100 bases:

>100_bases
AGCGGCAATATTGCTTGAACCAAGCTCTGGATTACCGGCGTGCTTCTAAAATTATCTATTCCAGCAGTGCAATAGTCGAT
ACAGGAAATATCAGAAAAAG

Downstream 100 bases:

>100_bases
GAAAGGGGAAAGAGGTCAGCCGTGGCCCAGACGCAGCATCGTATCGTCATAAAGAAAGTAAGGAGACAAAGCCAGGGGCA
CGGAGGCCAGTGGAAGATTG

Product: chemotaxis (motility protein A) transmembrane

Products: NA

Alternate protein names: Chemotaxis protein MotA [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MLVIIGSLIVLGSVFGGFALTGGHLAALFQPVELLMIGGAAMGAFTLGNTKKALKATLKSLPKVVQPPRYTKALYMDLMA
LLYDLLVKVRKEGLMSIEPDVDDPNESAIFANYPDILAEPVALEFLTDYLRLMVAGNLNAFELENLMDNEIETHHQEGEI
PVHCISRLADSMPAFGIVAAVMGVIHTMASVGLPPSELGVLVAQALVGTFLGILLGYGFVGPVASILEQRLNESTKILQC
IRVTLLASINGYTPALAVEFGRKVLYSTERPSFAELESHVRRAKDK

Sequences:

>Translated_286_residues
MLVIIGSLIVLGSVFGGFALTGGHLAALFQPVELLMIGGAAMGAFTLGNTKKALKATLKSLPKVVQPPRYTKALYMDLMA
LLYDLLVKVRKEGLMSIEPDVDDPNESAIFANYPDILAEPVALEFLTDYLRLMVAGNLNAFELENLMDNEIETHHQEGEI
PVHCISRLADSMPAFGIVAAVMGVIHTMASVGLPPSELGVLVAQALVGTFLGILLGYGFVGPVASILEQRLNESTKILQC
IRVTLLASINGYTPALAVEFGRKVLYSTERPSFAELESHVRRAKDK
>Mature_286_residues
MLVIIGSLIVLGSVFGGFALTGGHLAALFQPVELLMIGGAAMGAFTLGNTKKALKATLKSLPKVVQPPRYTKALYMDLMA
LLYDLLVKVRKEGLMSIEPDVDDPNESAIFANYPDILAEPVALEFLTDYLRLMVAGNLNAFELENLMDNEIETHHQEGEI
PVHCISRLADSMPAFGIVAAVMGVIHTMASVGLPPSELGVLVAQALVGTFLGILLGYGFVGPVASILEQRLNESTKILQC
IRVTLLASINGYTPALAVEFGRKVLYSTERPSFAELESHVRRAKDK

Specific function: MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel. Overexpression of MotA, with or without MotB, restores motility in a yhjH disruption, (a c-di-GM

COG id: COG1291

COG function: function code N; Flagellar motor component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MotA family [H]

Homologues:

Organism=Escherichia coli, GI1788199, Length=285, Percent_Identity=57.1929824561403, Blast_Score=363, Evalue=1e-102,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000540
- InterPro:   IPR022522
- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 30838; Mature: 30838

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS01307 MOTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVIIGSLIVLGSVFGGFALTGGHLAALFQPVELLMIGGAAMGAFTLGNTKKALKATLKS
CEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHH
LPKVVQPPRYTKALYMDLMALLYDLLVKVRKEGLMSIEPDVDDPNESAIFANYPDILAEP
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCHHHHHHH
VALEFLTDYLRLMVAGNLNAFELENLMDNEIETHHQEGEIPVHCISRLADSMPAFGIVAA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHH
VMGVIHTMASVGLPPSELGVLVAQALVGTFLGILLGYGFVGPVASILEQRLNESTKILQC
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
IRVTLLASINGYTPALAVEFGRKVLYSTERPSFAELESHVRRAKDK
HHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MLVIIGSLIVLGSVFGGFALTGGHLAALFQPVELLMIGGAAMGAFTLGNTKKALKATLKS
CEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHH
LPKVVQPPRYTKALYMDLMALLYDLLVKVRKEGLMSIEPDVDDPNESAIFANYPDILAEP
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCHHHHHHH
VALEFLTDYLRLMVAGNLNAFELENLMDNEIETHHQEGEIPVHCISRLADSMPAFGIVAA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHH
VMGVIHTMASVGLPPSELGVLVAQALVGTFLGILLGYGFVGPVASILEQRLNESTKILQC
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
IRVTLLASINGYTPALAVEFGRKVLYSTERPSFAELESHVRRAKDK
HHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6090403; 9097040; 9278503; 3007435; 1719217; 7643400 [H]