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The map label for this gene is ccmE

Identifier: 82702339

GI number: 82702339

Start: 1396402

End: 1396848

Strand: Reverse

Name: ccmE

Synonym: Nmul_A1210

Alternate gene names: 82702339

Gene position: 1396848-1396402 (Counterclockwise)

Preceding gene: 82702340

Following gene: 82702338

Centisome position: 43.87

GC content: 55.03

Gene sequence:

>447_bases
ATGAAACCACGTCATAAAAAATTGGCAATCATCGCTTCGAGCGTGACCGCGCTGGGCGTTGCTTCGGTGCTGGTTTTAAA
CGCATTTCAGAGTAATCTCGTATTTTTCTTCAGCCCTACCCAGGTGGCCAATAATGAAGCACCCGTTGGCAAGAGTTTCC
GTATCGGCGGCCTCGTGGAAGAAGGCAGCGTCAAACGCCAGGCCGACGGCGTGACGGTCAATTTCCTGGTGACGGATACC
GCAAAGGTTATTCCGGTCGTATATACCGGCATCCTTCCCGACCTGTTCAAGGAAGGCAAAGGCGTGGTAGCCCAGGGCAA
GCTGGCTTCGGATGGCATTTTCCGGGCGGACGAGGTGCTCGCGAAGCACGATGAAAATTATATGCCACCGGAAGCCGCGG
GCGCGCTTGATCAAGCCGACAAGGCTCGCAAGACAGTGATGCAGTAG

Upstream 100 bases:

>100_bases
ATCTGCATTGCAGGGGAAATCGTTCTGGTTTCCAACCGCAGGCGAACTTTGCTCAGGCATCTCAGTCTGATTCATCAGTC
AACAAAACAAGAGAAGGGAA

Downstream 100 bases:

>100_bases
CAAAAAGTTTCGCCCCGAGCCCTTCCCGAACCGAAAGGGCTCTGTCATTCCTGCTCATATCTATTCATATTTTCCATAAC
CCACAGCCTCAGCCATGATT

Product: cytochrome c-type biogenesis protein CcmE

Products: NA

Alternate protein names: Cytochrome c maturation protein E; Heme chaperone CcmE

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MKPRHKKLAIIASSVTALGVASVLVLNAFQSNLVFFFSPTQVANNEAPVGKSFRIGGLVEEGSVKRQADGVTVNFLVTDT
AKVIPVVYTGILPDLFKEGKGVVAQGKLASDGIFRADEVLAKHDENYMPPEAAGALDQADKARKTVMQ

Sequences:

>Translated_148_residues
MKPRHKKLAIIASSVTALGVASVLVLNAFQSNLVFFFSPTQVANNEAPVGKSFRIGGLVEEGSVKRQADGVTVNFLVTDT
AKVIPVVYTGILPDLFKEGKGVVAQGKLASDGIFRADEVLAKHDENYMPPEAAGALDQADKARKTVMQ
>Mature_148_residues
MKPRHKKLAIIASSVTALGVASVLVLNAFQSNLVFFFSPTQVANNEAPVGKSFRIGGLVEEGSVKRQADGVTVNFLVTDT
AKVIPVVYTGILPDLFKEGKGVVAQGKLASDGIFRADEVLAKHDENYMPPEAAGALDQADKARKTVMQ

Specific function: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH

COG id: COG2332

COG function: function code O; Cytochrome c-type biogenesis protein CcmE

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmE/CycJ family

Homologues:

Organism=Escherichia coli, GI1788525, Length=140, Percent_Identity=41.4285714285714, Blast_Score=111, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CCME_NITMU (Q2Y9Q8)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_411905.1
- ProteinModelPortal:   Q2Y9Q8
- SMR:   Q2Y9Q8
- STRING:   Q2Y9Q8
- GeneID:   3786141
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A1210
- eggNOG:   COG2332
- HOGENOM:   HBG296631
- OMA:   ICFCSAC
- PhylomeDB:   Q2Y9Q8
- ProtClustDB:   PRK13254
- BioCyc:   NMUL323848:NMUL_A1210-MONOMER
- HAMAP:   MF_01959
- InterPro:   IPR004329
- InterPro:   IPR012340
- Gene3D:   G3DSA:2.40.50.140

Pfam domain/function: PF03100 CcmE; SSF82093 Pyrv/PenolPyrv_Kinase_cat

EC number: NA

Molecular weight: Translated: 15755; Mature: 15755

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: BINDING 123-123

Signals:

None

Transmembrane regions:

HASH(0x133fbee8)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPRHKKLAIIASSVTALGVASVLVLNAFQSNLVFFFSPTQVANNEAPVGKSFRIGGLVE
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHCCCCCCCCCCEEECCEEC
EGSVKRQADGVTVNFLVTDTAKVIPVVYTGILPDLFKEGKGVVAQGKLASDGIFRADEVL
CCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHH
AKHDENYMPPEAAGALDQADKARKTVMQ
HHCCCCCCCCHHCCCHHHHHHHHHHHCH
>Mature Secondary Structure
MKPRHKKLAIIASSVTALGVASVLVLNAFQSNLVFFFSPTQVANNEAPVGKSFRIGGLVE
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHCCCCCCCCCCEEECCEEC
EGSVKRQADGVTVNFLVTDTAKVIPVVYTGILPDLFKEGKGVVAQGKLASDGIFRADEVL
CCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHH
AKHDENYMPPEAAGALDQADKARKTVMQ
HHCCCCCCCCHHCCCHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA