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The map label for this gene is ctaA

Identifier: 82702333

GI number: 82702333

Start: 1390187

End: 1391257

Strand: Direct

Name: ctaA

Synonym: Nmul_A1204

Alternate gene names: 82702333

Gene position: 1390187-1391257 (Clockwise)

Preceding gene: 82702332

Following gene: 82702342

Centisome position: 43.66

GC content: 51.91

Gene sequence:

>1071_bases
ATGCAGTTTGTCCAAACTTCAACACTTCCGCAAAAAACCGATCAAAAGTTTGCTGTGCAGAAACCGATTGCTATCTGGTT
GTTCGTTTGCTGCGCTCTGGTATTCGCCATGGTGGTTGTAGGCGGTGTAACCCGTCTTACCGATTCAGGGCTTTCCATCG
TCGAATGGCAACCCCTCGTTGGCACGGTTCCTCCACTCAGCCAGAATGACTGGGATGAGCTCTTCGAGAAATATCACCAG
ACGCCTCAGTATAAAAAGGTAAATCTTGGCATGAGCCTGGAAGAGTTCAAGACAATCTTCTGGTGGGAATATTTCCACCG
CTTATTGGGGCGCGTCATCGGGTTGGCATTTTTCATACCATTCCTGTATTTTCTGATGAAAAAGGCAGTCGACCGGCCAC
TGGGACTGAAGTTGTCAGGAATTTTCCTGCTGGGGGCTTTGCAGGGTGGGATGGGATGGTACATGGTAAAGAGCGGGTTG
GTGGATAACCCCCACGTCAGCCAGTATCGTCTGACTGCGCACTTGGGTCTCGCTTTCGCGATTTATGCCGCAATGTTCTG
GGTAGCCCTCGATCTGCTCAATCCCGGCCGCGGTTTGTCCGCAAACAGCGGACTGCGTGGTTTGCTCAATTTCTCCACCA
TGCTGTCTGCCCTGGTATTCATAATGGTTTTATCGGGCGGGTTCGTGGCAGGCATTCGGGCAGGTCTGGCTTACAATACT
TTTCCACTCATGGATGGCCACTTCATCCCCCCGGAACTATTCATGCTGGAACCCTGGTACCGGAATTTCTTCGACAATAT
GACCACTGTGCAATTCGACCATCGCCTGATTGCATGGACACTGGCAATTCTCGTTCCGATTTTCTGGCTCAAATCGAGAG
CAGTGCCACTTTCAGGCTCGGCTCGTCTTGCATGCACTCTACTGTTGATCATGCTGGCAGTGCAGATCACTCTGGGGATT
TCCACGCTGCTGCTGGTTGTTCCTCTAACCCTCGCGGCAGCACATCAGGCAGGCGCACTACTGTTGTTTACCGCTGCCCT
TTGGGTGAATCATGAGCTACGGCGCCAATAG

Upstream 100 bases:

>100_bases
GCGAATCCGAGAAGCAGAAAGAGTGGGAACGCGACAAGCAGCGGTTGATGCGTCCAAAATAATCCTCGATATTTTATAAC
CTTAGATCAAATTCCTAGCC

Downstream 100 bases:

>100_bases
TTGAGCGTTTCAGTCCGTCGGCAGCGGGCCGCTCCAGGAGTTTGGCCTCGACGCCTTTATCCACCGCGCAGGGCATGGTC
GGTGAATGATTTTTTTGATT

Product: cytochrome oxidase assembly

Products: NA

Alternate protein names: HAS; Cytochrome aa3-controlling protein

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MQFVQTSTLPQKTDQKFAVQKPIAIWLFVCCALVFAMVVVGGVTRLTDSGLSIVEWQPLVGTVPPLSQNDWDELFEKYHQ
TPQYKKVNLGMSLEEFKTIFWWEYFHRLLGRVIGLAFFIPFLYFLMKKAVDRPLGLKLSGIFLLGALQGGMGWYMVKSGL
VDNPHVSQYRLTAHLGLAFAIYAAMFWVALDLLNPGRGLSANSGLRGLLNFSTMLSALVFIMVLSGGFVAGIRAGLAYNT
FPLMDGHFIPPELFMLEPWYRNFFDNMTTVQFDHRLIAWTLAILVPIFWLKSRAVPLSGSARLACTLLLIMLAVQITLGI
STLLLVVPLTLAAAHQAGALLLFTAALWVNHELRRQ

Sequences:

>Translated_356_residues
MQFVQTSTLPQKTDQKFAVQKPIAIWLFVCCALVFAMVVVGGVTRLTDSGLSIVEWQPLVGTVPPLSQNDWDELFEKYHQ
TPQYKKVNLGMSLEEFKTIFWWEYFHRLLGRVIGLAFFIPFLYFLMKKAVDRPLGLKLSGIFLLGALQGGMGWYMVKSGL
VDNPHVSQYRLTAHLGLAFAIYAAMFWVALDLLNPGRGLSANSGLRGLLNFSTMLSALVFIMVLSGGFVAGIRAGLAYNT
FPLMDGHFIPPELFMLEPWYRNFFDNMTTVQFDHRLIAWTLAILVPIFWLKSRAVPLSGSARLACTLLLIMLAVQITLGI
STLLLVVPLTLAAAHQAGALLLFTAALWVNHELRRQ
>Mature_356_residues
MQFVQTSTLPQKTDQKFAVQKPIAIWLFVCCALVFAMVVVGGVTRLTDSGLSIVEWQPLVGTVPPLSQNDWDELFEKYHQ
TPQYKKVNLGMSLEEFKTIFWWEYFHRLLGRVIGLAFFIPFLYFLMKKAVDRPLGLKLSGIFLLGALQGGMGWYMVKSGL
VDNPHVSQYRLTAHLGLAFAIYAAMFWVALDLLNPGRGLSANSGLRGLLNFSTMLSALVFIMVLSGGFVAGIRAGLAYNT
FPLMDGHFIPPELFMLEPWYRNFFDNMTTVQFDHRLIAWTLAILVPIFWLKSRAVPLSGSARLACTLLLIMLAVQITLGI
STLLLVVPLTLAAAHQAGALLLFTAALWVNHELRRQ

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 2 subfamily

Homologues:

Organism=Homo sapiens, GI17921985, Length=356, Percent_Identity=44.3820224719101, Blast_Score=283, Evalue=1e-76,
Organism=Homo sapiens, GI17921987, Length=316, Percent_Identity=42.0886075949367, Blast_Score=237, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI17536069, Length=353, Percent_Identity=41.643059490085, Blast_Score=246, Evalue=1e-65,
Organism=Saccharomyces cerevisiae, GI6320989, Length=379, Percent_Identity=39.8416886543536, Blast_Score=247, Evalue=2e-66,
Organism=Drosophila melanogaster, GI19922860, Length=371, Percent_Identity=40.1617250673854, Blast_Score=251, Evalue=7e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CTAA_NITMU (Q2Y9R4)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_411899.1
- STRING:   Q2Y9R4
- GeneID:   3786135
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A1204
- eggNOG:   COG1612
- HOGENOM:   HBG628966
- OMA:   GLSIVEW
- PhylomeDB:   Q2Y9R4
- ProtClustDB:   CLSK2758227
- BioCyc:   NMUL323848:NMUL_A1204-MONOMER
- HAMAP:   MF_01665
- InterPro:   IPR003780

Pfam domain/function: PF02628 COX15-CtaA

EC number: NA

Molecular weight: Translated: 39860; Mature: 39860

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: BINDING 335-335

Signals:

None

Transmembrane regions:

HASH(0x10590628)-; HASH(0x13402fc0)-; HASH(0x1331b730)-; HASH(0x1333427c)-; HASH(0x131c2e04)-; HASH(0x128c8410)-; HASH(0x13423468)-; HASH(0x13402e70)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFVQTSTLPQKTDQKFAVQKPIAIWLFVCCALVFAMVVVGGVTRLTDSGLSIVEWQPLV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEECCCCC
GTVPPLSQNDWDELFEKYHQTPQYKKVNLGMSLEEFKTIFWWEYFHRLLGRVIGLAFFIP
CCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLYFLMKKAVDRPLGLKLSGIFLLGALQGGMGWYMVKSGLVDNPHVSQYRLTAHLGLAFA
HHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
IYAAMFWVALDLLNPGRGLSANSGLRGLLNFSTMLSALVFIMVLSGGFVAGIRAGLAYNT
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCC
FPLMDGHFIPPELFMLEPWYRNFFDNMTTVQFDHRLIAWTLAILVPIFWLKSRAVPLSGS
CCCCCCCCCCCHHEEECHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ARLACTLLLIMLAVQITLGISTLLLVVPLTLAAAHQAGALLLFTAALWVNHELRRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MQFVQTSTLPQKTDQKFAVQKPIAIWLFVCCALVFAMVVVGGVTRLTDSGLSIVEWQPLV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEECCCCC
GTVPPLSQNDWDELFEKYHQTPQYKKVNLGMSLEEFKTIFWWEYFHRLLGRVIGLAFFIP
CCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLYFLMKKAVDRPLGLKLSGIFLLGALQGGMGWYMVKSGLVDNPHVSQYRLTAHLGLAFA
HHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
IYAAMFWVALDLLNPGRGLSANSGLRGLLNFSTMLSALVFIMVLSGGFVAGIRAGLAYNT
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCC
FPLMDGHFIPPELFMLEPWYRNFFDNMTTVQFDHRLIAWTLAILVPIFWLKSRAVPLSGS
CCCCCCCCCCCHHEEECHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ARLACTLLLIMLAVQITLGISTLLLVVPLTLAAAHQAGALLLFTAALWVNHELRRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA