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The map label for this gene is luxQ [H]

Identifier: 82702320

GI number: 82702320

Start: 1378191

End: 1380284

Strand: Reverse

Name: luxQ [H]

Synonym: Nmul_A1191

Alternate gene names: 82702320

Gene position: 1380284-1378191 (Counterclockwise)

Preceding gene: 82702328

Following gene: 82702319

Centisome position: 43.35

GC content: 53.96

Gene sequence:

>2094_bases
ATGAACATCAGAAACTTTATCAGTTTTTCCAATGTCACCCTTGCGCTCCTGCTTGCGGCGATCGGTGCCCTCGTCTTTCA
TTCGATGGGTATTCGCCAGGAGATCAACATCGCGGAACGGCACCGGTTCCAGGCGCTGCTGCTCGGGGATGAACTGCTTC
ACACCTCCAACGACCTCACACGCATGGCCCGCACGTATGTGATCACCGGCGACCCGGTCTACAAGCGGTATTTCAACGAA
ATACTGGATATTCGCAACGGACTCCATCCACGCCCGGTGAATTATTCCCCGACATACTGGGACCTGATGATGGCGGGAAA
AACTCCCGTCGTCAGGCAAGGGCGTGCCGTTCCTTTGCGGGAGAGGTTTCAGCAAGAAGGCCTGAACAATGAAGAATATG
GCTTGCTGCAGCAATCGCTGGAACGCTCCGACAGGCTGGTCAAGCTTGAGCAGCGCGCCTTTGCCGCAATGGAAGGCTTA
TATGACGACGGTGAAGGCAATTTTACCGTGCGCGGCAAACCCGACCGTGACCTCGCGATAAAGCTTCTGTTCAGTGAGCA
GTATATTGCAGAAAAAGCCGCTGTCATGGAGCCGATTCAGGCGTTCATGGACTTATTCGGTGAACGCATGCAAACTCAAT
CAAATCTCGGGCTGGCGCGACTCGAGCGCCAGATCATCTTCGAGATGGCGCTTATCTTCGTTGCCCTGGTAGCCACCATG
GGCATCATTTTTTATACCCGGCTCAACATACTACGGCCGTTGGCCGATCTGGGCCGGCAGGTCGCGGGAGCCACTCGGGG
CATTCTTCCCAGCCGCTATGGGAAAGCGACGAGTAATGAGGTTGCCAAGCTCGGCGAAGCATTAGCCCTCGCAGATGCGG
AAAAACGGCAACTTCTCGAGAATGAAACAATCGCCCGAAATGAAGCTGAGCGCGCAAGCCGCCTCAAGGACGAGTTTCTG
GCAACCCTTTCTCATGAATTGAGAACCCCGTTAAACGCAATCCTGGGATGGTCCCAACTCATCCTGAGTGGAAACCTTAA
AAAAGAGGACATCCACCGGGGACTGGAAACGATCGAGCGAAATGCGCGTGTCCAGAACAAGCTGATTGAAGACCTCCTCG
ACATGAGCAGCATCATCTCCGGAAAAGTCAGGCTGGATATGCGGCGGCAGGATATCGCCAACCTGGTCGAGACAGCGGTC
GAATCAGTAAAGCCGACAGCGCAGGCCAAAGGAGTCATTCTGAAAAAAACGCTGGGCAAAAAATTCGATTCCATCATCGG
AGATTCCAACCGGCTCCAGCAGATACTCTGGAACCTGCTCTCCAATTCGATAAAATTCACGCCCAAGGGGGGGAAAATAG
AAGTTACAGTAGAACAGCGAAACTTGTTCCTCGAAATCAGGATAAGCGACTCCGGTTCGGGAATCACTTCCGCATTCATG
CCCTATGTCTTTGATCGCTTCCGGCAGGGAGACGCTTCGCTTACGCGGCAGTACGGCGGCCTCGGTCTTGGTCTTGCCAT
TGTGAAACAACTGGTGGAACTTCACGGTGGAACGGTGCGTGCAGAAAGTCCGGGTGAGGGACAAGGATCATCCTTTATCG
TAAACCTGCCGGTCGCTCCTCCTGTTTCCGAAACAAAAAGCGAACCGCTCCCTCCGCAGGAATGCATCGAACCGCAGGCG
TTATTCAAGGGATTGAAAGTGCTGGTTGTCGATGATGAACTGGATGCACGCGAACTCATCAGGCGGATTCTGGCGCAGCA
GGAAGCAAGTGTGATTACGGCTGCACGGGCGACAGATGGCCTGGAACTCTTAAAGACCGAGAAGCCGGATATCGTTATCA
GCGATATCAGCATGCCCGAAAAAAACGGGTATCAGTTCATCGCCGAGGTGAGAAGCCTTTCGGCAGAAAATGGGGGAACA
ATCCCGGCTATCGCCCTCACGGCATTCGCCCATCCGGAGGACAGGGCCAAAATGATGAGCGCAGGCTACCAGAAACACCT
GCCCAAGCCCGTGGATTCCGTTGCATTGATTATAGCCATCGATAACCTGGTCGGCTCAAAAAAGCTGGCCCATACCAGCA
CTAGCGCTACCTGA

Upstream 100 bases:

>100_bases
AGTCTGTAAATAAATCGCGCTCCGGAGTCCAGGCGTATAAAATTAAAACAGGCAATTGATGCGATAGAAAATGGACGGGC
AATTGCAGCGGGATGGGTTT

Downstream 100 bases:

>100_bases
CCAACCATATCTTCAGGTGCCGCAACCGCATTAACTTGTCATCCCGGCCCTCAAGATTCTCCTCCCCGAACGGATTCCCC
CGCTGCGCATCTCCAGGTTG

Product: periplasmic sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 697; Mature: 697

Protein sequence:

>697_residues
MNIRNFISFSNVTLALLLAAIGALVFHSMGIRQEINIAERHRFQALLLGDELLHTSNDLTRMARTYVITGDPVYKRYFNE
ILDIRNGLHPRPVNYSPTYWDLMMAGKTPVVRQGRAVPLRERFQQEGLNNEEYGLLQQSLERSDRLVKLEQRAFAAMEGL
YDDGEGNFTVRGKPDRDLAIKLLFSEQYIAEKAAVMEPIQAFMDLFGERMQTQSNLGLARLERQIIFEMALIFVALVATM
GIIFYTRLNILRPLADLGRQVAGATRGILPSRYGKATSNEVAKLGEALALADAEKRQLLENETIARNEAERASRLKDEFL
ATLSHELRTPLNAILGWSQLILSGNLKKEDIHRGLETIERNARVQNKLIEDLLDMSSIISGKVRLDMRRQDIANLVETAV
ESVKPTAQAKGVILKKTLGKKFDSIIGDSNRLQQILWNLLSNSIKFTPKGGKIEVTVEQRNLFLEIRISDSGSGITSAFM
PYVFDRFRQGDASLTRQYGGLGLGLAIVKQLVELHGGTVRAESPGEGQGSSFIVNLPVAPPVSETKSEPLPPQECIEPQA
LFKGLKVLVVDDELDARELIRRILAQQEASVITAARATDGLELLKTEKPDIVISDISMPEKNGYQFIAEVRSLSAENGGT
IPAIALTAFAHPEDRAKMMSAGYQKHLPKPVDSVALIIAIDNLVGSKKLAHTSTSAT

Sequences:

>Translated_697_residues
MNIRNFISFSNVTLALLLAAIGALVFHSMGIRQEINIAERHRFQALLLGDELLHTSNDLTRMARTYVITGDPVYKRYFNE
ILDIRNGLHPRPVNYSPTYWDLMMAGKTPVVRQGRAVPLRERFQQEGLNNEEYGLLQQSLERSDRLVKLEQRAFAAMEGL
YDDGEGNFTVRGKPDRDLAIKLLFSEQYIAEKAAVMEPIQAFMDLFGERMQTQSNLGLARLERQIIFEMALIFVALVATM
GIIFYTRLNILRPLADLGRQVAGATRGILPSRYGKATSNEVAKLGEALALADAEKRQLLENETIARNEAERASRLKDEFL
ATLSHELRTPLNAILGWSQLILSGNLKKEDIHRGLETIERNARVQNKLIEDLLDMSSIISGKVRLDMRRQDIANLVETAV
ESVKPTAQAKGVILKKTLGKKFDSIIGDSNRLQQILWNLLSNSIKFTPKGGKIEVTVEQRNLFLEIRISDSGSGITSAFM
PYVFDRFRQGDASLTRQYGGLGLGLAIVKQLVELHGGTVRAESPGEGQGSSFIVNLPVAPPVSETKSEPLPPQECIEPQA
LFKGLKVLVVDDELDARELIRRILAQQEASVITAARATDGLELLKTEKPDIVISDISMPEKNGYQFIAEVRSLSAENGGT
IPAIALTAFAHPEDRAKMMSAGYQKHLPKPVDSVALIIAIDNLVGSKKLAHTSTSAT
>Mature_697_residues
MNIRNFISFSNVTLALLLAAIGALVFHSMGIRQEINIAERHRFQALLLGDELLHTSNDLTRMARTYVITGDPVYKRYFNE
ILDIRNGLHPRPVNYSPTYWDLMMAGKTPVVRQGRAVPLRERFQQEGLNNEEYGLLQQSLERSDRLVKLEQRAFAAMEGL
YDDGEGNFTVRGKPDRDLAIKLLFSEQYIAEKAAVMEPIQAFMDLFGERMQTQSNLGLARLERQIIFEMALIFVALVATM
GIIFYTRLNILRPLADLGRQVAGATRGILPSRYGKATSNEVAKLGEALALADAEKRQLLENETIARNEAERASRLKDEFL
ATLSHELRTPLNAILGWSQLILSGNLKKEDIHRGLETIERNARVQNKLIEDLLDMSSIISGKVRLDMRRQDIANLVETAV
ESVKPTAQAKGVILKKTLGKKFDSIIGDSNRLQQILWNLLSNSIKFTPKGGKIEVTVEQRNLFLEIRISDSGSGITSAFM
PYVFDRFRQGDASLTRQYGGLGLGLAIVKQLVELHGGTVRAESPGEGQGSSFIVNLPVAPPVSETKSEPLPPQECIEPQA
LFKGLKVLVVDDELDARELIRRILAQQEASVITAARATDGLELLKTEKPDIVISDISMPEKNGYQFIAEVRSLSAENGGT
IPAIALTAFAHPEDRAKMMSAGYQKHLPKPVDSVALIIAIDNLVGSKKLAHTSTSAT

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=246, Percent_Identity=38.2113821138211, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1788713, Length=389, Percent_Identity=30.5912596401028, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI48994928, Length=378, Percent_Identity=33.0687830687831, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI87081816, Length=389, Percent_Identity=28.2776349614396, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI145693157, Length=240, Percent_Identity=35, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1788393, Length=229, Percent_Identity=30.1310043668122, Blast_Score=106, Evalue=6e-24,
Organism=Escherichia coli, GI1786783, Length=314, Percent_Identity=27.3885350318471, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1786912, Length=255, Percent_Identity=30.5882352941176, Blast_Score=102, Evalue=9e-23,
Organism=Escherichia coli, GI1790436, Length=245, Percent_Identity=28.1632653061224, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1786600, Length=223, Percent_Identity=28.6995515695067, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788279, Length=214, Percent_Identity=31.3084112149533, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1790861, Length=347, Percent_Identity=28.8184438040346, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1788549, Length=250, Percent_Identity=30, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790346, Length=236, Percent_Identity=28.8135593220339, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787894, Length=324, Percent_Identity=24.3827160493827, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI87082128, Length=321, Percent_Identity=25.2336448598131, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1789403, Length=229, Percent_Identity=25.3275109170306, Blast_Score=63, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=91, Percent_Identity=40.6593406593407, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 77304; Mature: 77304

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIRNFISFSNVTLALLLAAIGALVFHSMGIRQEINIAERHRFQALLLGDELLHTSNDLT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHCCHHHH
RMARTYVITGDPVYKRYFNEILDIRNGLHPRPVNYSPTYWDLMMAGKTPVVRQGRAVPLR
HHHHHEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHEECCCCCHHCCCCCCCHH
ERFQQEGLNNEEYGLLQQSLERSDRLVKLEQRAFAAMEGLYDDGEGNFTVRGKPDRDLAI
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCEE
KLLFSEQYIAEKAAVMEPIQAFMDLFGERMQTQSNLGLARLERQIIFEMALIFVALVATM
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
GIIFYTRLNILRPLADLGRQVAGATRGILPSRYGKATSNEVAKLGEALALADAEKRQLLE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
NETIARNEAERASRLKDEFLATLSHELRTPLNAILGWSQLILSGNLKKEDIHRGLETIER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
NARVQNKLIEDLLDMSSIISGKVRLDMRRQDIANLVETAVESVKPTAQAKGVILKKTLGK
HHHHHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHH
KFDSIIGDSNRLQQILWNLLSNSIKFTPKGGKIEVTVEQRNLFLEIRISDSGSGITSAFM
HHHHHHCCHHHHHHHHHHHHCCCEEECCCCCEEEEEEEECCEEEEEEECCCCCCHHHHHH
PYVFDRFRQGDASLTRQYGGLGLGLAIVKQLVELHGGTVRAESPGEGQGSSFIVNLPVAP
HHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEECCCCC
PVSETKSEPLPPQECIEPQALFKGLKVLVVDDELDARELIRRILAQQEASVITAARATDG
CCCCCCCCCCCHHHHCCHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
LELLKTEKPDIVISDISMPEKNGYQFIAEVRSLSAENGGTIPAIALTAFAHPEDRAKMMS
HHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHH
AGYQKHLPKPVDSVALIIAIDNLVGSKKLAHTSTSAT
CCHHHCCCCCHHHEEEEEEEHHHHCCCHHCCCCCCCC
>Mature Secondary Structure
MNIRNFISFSNVTLALLLAAIGALVFHSMGIRQEINIAERHRFQALLLGDELLHTSNDLT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHCCHHHH
RMARTYVITGDPVYKRYFNEILDIRNGLHPRPVNYSPTYWDLMMAGKTPVVRQGRAVPLR
HHHHHEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHEECCCCCHHCCCCCCCHH
ERFQQEGLNNEEYGLLQQSLERSDRLVKLEQRAFAAMEGLYDDGEGNFTVRGKPDRDLAI
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCEE
KLLFSEQYIAEKAAVMEPIQAFMDLFGERMQTQSNLGLARLERQIIFEMALIFVALVATM
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
GIIFYTRLNILRPLADLGRQVAGATRGILPSRYGKATSNEVAKLGEALALADAEKRQLLE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
NETIARNEAERASRLKDEFLATLSHELRTPLNAILGWSQLILSGNLKKEDIHRGLETIER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
NARVQNKLIEDLLDMSSIISGKVRLDMRRQDIANLVETAVESVKPTAQAKGVILKKTLGK
HHHHHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHH
KFDSIIGDSNRLQQILWNLLSNSIKFTPKGGKIEVTVEQRNLFLEIRISDSGSGITSAFM
HHHHHHCCHHHHHHHHHHHHCCCEEECCCCCEEEEEEEECCEEEEEEECCCCCCHHHHHH
PYVFDRFRQGDASLTRQYGGLGLGLAIVKQLVELHGGTVRAESPGEGQGSSFIVNLPVAP
HHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEECCCCC
PVSETKSEPLPPQECIEPQALFKGLKVLVVDDELDARELIRRILAQQEASVITAARATDG
CCCCCCCCCCCHHHHCCHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
LELLKTEKPDIVISDISMPEKNGYQFIAEVRSLSAENGGTIPAIALTAFAHPEDRAKMMS
HHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHH
AGYQKHLPKPVDSVALIIAIDNLVGSKKLAHTSTSAT
CCHHHCCCCCHHHEEEEEEEHHHHCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]